Ctcf Protein Jobs in Usa

• Design and lead recombinant protein expression and purification strategies for challenging therapeutic targets, including optimization and scale-up (10 L or larger).
• Develop and execute advanced chromatography workflows using affinity, ion exchange, and size exclusion purification on AKTA FPLC systems.
• Innovate and implement strategies to successfully express and purify complex or difficult protein targets.
• Lead scientific troubleshooting for challenging protein production campaigns.
• Contribute to analytical characterization efforts to evaluate protein purity, stability, and functionality.
• Support and help expand the organization’s protein sciences platform and capabilities.
• Collaborate closely with structural biology, biochemistry, medicinal chemistry, and translational research teams to deliver high-quality protein reagents for discovery programs.
• Present experimental strategies, interpret results, and provide scientific insight in cross-functional team discussions.
• Influence project strategy and contribute to decisions that advance therapeutic programs.
• Foster a culture of scientific rigor, collaboration, and innovation.

Qualifications:

• Ph.D. in Biochemistry, Molecular Biology, Biology, or a related discipline.
• Approximately 3–6 years of post-graduate experience in protein expression and characterization.
• Demonstrated scientific productivity, including peer-reviewed publications.
• Extensive hands-on experience with recombinant protein expression across multiple systems, including bacterial, insect, mammalian, and/or yeast platforms.
• Deep expertise in protein purification and chromatography workflows, particularly using AKTA FPLC systems.
• Strong experience with protein characterization techniques, such as SDS-PAGE, SEC, DLS, DSF, MALS, LC-MS, and NMR.
• Proven ability to independently design experiments, troubleshoot complex challenges, and deliver results.
• Excellent communication skills with the ability to collaborate and influence across multidisciplinary teams.

Estimated Min Rate: $66.50
Estimated Max Rate: $95.00

What’s In It for You?
We welcome you to be a part of the largest and legendary global staffing companies to meet your career aspirations. Yoh’s network of client companies has been employing professionals like you for over 65 years in the U.S., UK and Canada. Join Yoh’s extensive talent community that will provide you with access to Yoh’s vast network of opportunities and gain access to this exclusive opportunity available to you. Benefit eligibility is in accordance with applicable laws and client requirements. Benefits include:

• Medical, Prescription, Dental & Vision Benefits (for employees working 20+ hours per week)
• Health Savings Account (HSA) (for employees working 20+ hours per week)
• Life & Disability Insurance (for employees working 20+ hours per week)
• MetLife Voluntary Benefits
• Employee Assistance Program (EAP)
• 401K Retirement Savings Plan
• Direct Deposit & weekly epayroll
• Referral Bonus Programs
• Certification and training opportunities

Note: Any pay ranges displayed are estimations. Actual pay is determined by an applicant's experience, technical expertise, and other qualifications as listed in the job description. All qualified applicants are welcome to apply.

Yoh, a Day & Zimmermann company, is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, or status as a protected veteran.

Visit to contact us if you are an individual with a disability and require accommodation in the application process.

For California applicants, qualified applicants with arrest or conviction records will be considered for employment in accordance with the Los Angeles County Fair Chance Ordinance for Employers and the California Fair Chance Act. All of the material job duties described in this posting are job duties for which a criminal history may have a direct, adverse, and negative relationship potentially resulting in the withdrawal of a conditional offer of employment.

It is unlawful in Massachusetts to require or administer a lie detector test as a condition of employment or continued employment. An employer who violates this law shall be subject to criminal penalties and civil liability.

By applying and submitting your resume, you authorize Yoh to review and reformat your resume to meet Yoh’s hiring clients’ preferences. To learn more about Yoh’s privacy practices, please see our Candidate Privacy Notice: 

• Mission and Purpose: At St. Jude, working is more than just a job — it’s a calling. Each member of St. Jude is united by a shared purpose: finding cures and saving children. In addition to the meaningful work you will undertake, we offer a range of perks to enhance your experience.
• Community and Belonging: St. Jude is like a warm family that welcomes you, to a large part because it is a Children’s hospital.
• The Best of Both Worlds – Industry and Academia: St. Jude provides academic freedom in research and industrial efficiency and resources. We have access to world-class shared resources/facilities led by expert scientists, coupled with state-of-the-art technology and funding, accelerating research productivity.
• World-Class Benefits: St. Jude offers a world-class benefits package ( ). Enjoy comprehensive healthcare, a competitive salary, tuition assistance for continued education, and exceptional work-life balance with ample paid time off.
• Professional Growth: You will have access to opportunities to enhance your professional growth in terms of scientific skills, soft skills, and your career (St. Jude has well defined career path).
• Diversity: St. Jude is dedicated to fostering an inclusive and diverse scientific community, where everyone’s contributions are valued. More information is available here.
• Competitive Compensation: Embark on your journey with a competitive salary (depending on experience) comprehensive benefits and generous relocation assistance, reflecting our commitment to recognize and invest in talent. Furthermore, in Memphis/Tennessee, there is no income tax.
• Personalized Guidance: Dr. Gorgulla is committed to providing hands-on mentorship tailored to your needs and career aspirations. Whether you are refining scientific techniques or soft skills, you will have his full support.
• Modern Buildings and Spaces: Our research group and wet lab is located in the newest building of the campus, the Inspiration 4 – Advanced Research Center, that cost of $400 million to construct. 
• Additional Perks: St. Jude offers many special perks, such as an on-site gym, an employee pharmacy, and many others. To learn more about the unexpected perks of working at St. Jude, visit our website at  Employer

  
  

  • St. Jude Named #2 on Forbes America's Dream Employers: Jude is a Top Employer for Women: St. Jude is also among the top 10 employers for women in the US:  Jude is a high school and college students’ top “dream employer”: According to the National Society of High School Scholars (NSHSS) 2018 Career Interest Survey:  .

  
  

  About Memphis

  
  

  St. Jude is located in the heart of Memphis, Tennessee, a vibrant and friendly city at the historic American crossroads of music, trade, food, and culture. Living in Memphis provides several unique advantages, including:

  
  

  • Breathtaking Nature: Memphis provides unique nature and scenery, such as the Mississippi (the largest river in the US) or Shelby Farms Park, with which 4,500 acres is one of the largest urban parks in the country. See   for more details.
  • Its Culture: It is for instance the home of Elvis Presley. See   for more details on the cultural aspects.
  • It’s Affordability: Memphis is one of the most affordable cities in the US, meaning the same income will bring you farther than in other places in the US (for more details, see  ).

  
  

  For a video with testimonials about how new St. Jude members experienced Memphis, see here: (depending on experience)

• St. Jude offers a generous moving allowance to cover your costs related to your move to Memphis.
• St. Jude provides temporary housing at reduced costs for several months after your move. 

Requirements

• PhD in chemistry, biochemistry, biophysics or structural biology, drug discovery, or a related area.

How to Apply

If you are interested in the above position, please apply via LinkedIn and submit:

• Cover letter (PDF format, "FirstName LastName - CĹ.pdf", sent via LinkedIn Message)
• CV (PDF format, named as "FirstName LastName - CV.pdf", sent via LinkedIn Application System)

Are you an experienced Sr Research Associate with a desire to excel? If so, then Talent Software Services may have the job for you! Our client is seeking an experienced Sr Research Associate to work in Novato, CA.

Position Summary: The selected candidate will work in the Separations and Biophysical Assays team within the Analytical Sciences group to assist in the advancement of clients' therapeutics for clinical evaluation and potential commercialisation. The candidate will be responsible for method development (separations), provide routine testing and characterization support to partner groups to help with early candidate selection, process development, and drug substance and drug product process characterization. The ideal candidate will have hands-on experience working with biologics including but not limited to proteins, peptides, protein-conjugates, enzymes, biologics with a focus on method development and in-depth characterization. The ideal candidate will be able to perform quality work under limited supervision, apply problem solving techniques to maintain accurate results, promote improvements, and assure a safe, stable, on-target operation within the laboratory. The selected candidate should possess excellent analytical, organizational and communication skills and be a self-starter willing to work efficiently and collaboratively in a dynamic environment. This role is primarily a laboratory position; contact with chemicals is part of the job. The role is fully onsite (5 days a week, 8-hour days) with occasional evening or weekend work required. The employee will be trained to use common lab equipment and minimize exposure to hazards. Desktop or laptop computer work is also a major component of the job. The work environment characteristics described here are representative of those an employee encounters while performing the essential functions of this job. Reasonable accommodations may be made to enable individuals with disabilities to perform the essential functions. While performing the duties of this job, the employee is occasionally exposed to work near moving mechanical parts; fumes or airborne particles; toxic or caustic chemicals; risk of electrical shock and vibration. The noise level in the work environment is usually moderate. The employee may frequently be required to sit and talk or hear. The employee is occasionally required to stand; walk; use hands to finger, handle, or feel; reach with hands and arms; climb or balance; stoop, knee crouch, or crawl and taste or smell. The employee must occasionally lift and/or move up to 25 pounds. Specific vision abilities in this job include close vision, depth perception and ability to adjust focus.

Primary Responsibilities/Accountabilities:

• Primary responsibility is to support the Separations and Biophysics group within Analytical Sciences
• Be a hands-on presence in the laboratory, supporting biophysical/ biochemical assay development and qualification using HPLC and CE (must have) for various modalities (preferably biologics). LC-MS (high-res) experience is also desirable.
• Provide routine analytical characterization & testing support to partner groups including Upstream and Downstream PD, Formulations, and Research & Early Development (RED).
• Document experimental results in the company electronic lab notebook (Benchling), author procedures, and contribute to technical documentation (test methods, development reports).
• Actively participate in the operational aspects of the laboratory by conducting safety inspections, lab organization, ordering supplies, and performing routine equipment maintenance.
• Present scientific literature and results from ongoing studies at group meetings and other discussion forums at the company.
• Other duties as assigned.

Qualifications:

• Bachelor's degree in Chemistry, Biochemistry, Analytical Chemistry, Chemical Engineering or a related field with 6+ years of experience in a Biologics or Pharmaceutical environment.
• Master's degree in Chemistry, Biochemistry, Analytical Chemistry, Chemical Engineering or a related field with 4+ years of experience in a Biologics or Pharmaceutical environment.
• Hands-on experience in the biotechnology industry or academic setting with a broad range of analytical techniques focused on analytical testing and characterization for proteins, peptides, and protein-conjugates is required.
• Experience with biochemical characterization methods is required:
• SEC, SCX, RP-HPLC experience is a must (Agilent/Waters/Thermo LC instruments)
• Capillary Electrophoresis (PA800 or BioPhase8800) based methods (SDS for size separation, glycan profiling)
• cIEF (Maurice) experience is highly desirable
• LC-MS (Orbitrap/QToF/QQQ) method development experience also desirable
• Technical understanding of all aspects of analytical testing, phase appropriate regulatory requirements, method qualifications, and method transfers.
• Ability to independently troubleshoot issues, ideate, and develop insights into technical challenges and propose solutions to solve them.
• Demonstrates attention-to-detail and "right-the-first time' approach
• Excellent written and oral communication skills, with the ability to communicate complex information. Be able to present data/ideas to functional and cross-functional teams.
• Ability to influence others effectively and develop collaborative relationships with partner teams.
• Familiar with use of statistical software, electronic document management, and laboratory information management.
• Ability to effectively analyze complex problems and present results effectively within and beyond the department
• Ability to flexibly adapt to changing business needs and meet timelines.
• Strong organizational skills with the ability to effectively multi-task and prioritize.

Preferred:

• Experience in method development, qualification, and transfer to/from other laboratories, such as development and quality control.
• Knowledge of biopharmaceutical process development is a plus.
• Experience with automation is a plus.
• Experience working in a cross-functional environment.
• Good understanding of root cause analysis methodology.

Bioinformatics Scientist – Antibody Discovery

A growing global veterinary pharmaceuticals organisation is looking for a Bioinformatics Scientist to support antibody discovery programmes for companion animals (dogs, cats, horses).

Working closely with senior R&D leadership, this role will focus on applying bioinformatics, sequencing data analysis and protein modelling to identify and optimize therapeutic antibody targets.

Key Responsibilities

• Analyse genomic, DNA-seq and RNA-seq datasets to support antibody discovery
• Apply bioinformatics and modelling approaches to evaluate and optimize antibody candidates
• Contribute to protein modelling and in-silico antibody engineering (e.g. liability remediation, biophysical optimization)
• Curate and integrate genomic datasets for companion animal species
• Collaborate closely with discovery biology and R&D teams

Key Requirements

• At least 1 year of experience working with therapeutic antibodies (essential)
• Experience analyzing next generation sequencing datasets (DNA / RNA-seq)
• Background in bioinformatics, computational biology or structural biology
• Familiarity with protein modelling / antibody engineering tools (e.g. MOLE, Rosetta or similar)
• Strong communication skills and ability to work cross-functionally with scientific teams

This is an exciting opportunity to contribute to cutting-edge biologics discovery in animal health, helping develop next-generation therapies for companion animals.

If interested, please reach out for a confidential discussion.

Join us and celebrate the beauty of human experience. Create for happier, healthier lives, with love for nature. Together, with our customers, we deliver food innovations, craft inspired fragrances and develop beauty and wellbeing solutions. There's much to learn and many to learn from, with more than 16,000 employees around the world to explore ideas and ambitions with.
In the USA, we develop, market and produce a wide array of solutions from our 25 most innovative sites, based across the country. Stretch your skills, create and get inspiration from passionate colleagues. Every day, your energy, your thirst for knowledge, and your creativity will shape our future, making a positive difference on billions of people. Every essence of you enriches our world. We are Givaudan. Human by nature.

Givaudan Flavors Science & Technology is looking for a Cheminformatics Scientist to join a versatile team advancing flavor ingredient discovery. You will apply cheminformatics, machine learning, and AI to develop novel aroma and taste molecules while collaborating across research teams to build data-driven discovery workflows.

Your Title: Cheminformatics Scientist

Your Location: Onsite (Givaudan facility)

You Will Report To: Flavors Science & Technology Computational Sciences Lead

Responsibilities

• 
  
• Design and implement cheminformatics algorithms and workflows to accelerate flavor ingredient discovery across aroma and taste modalities.
  
• Develop, validate, and deploy predictive models using QSAR, machine learning, artificial intelligence, and 2D/3D computational approaches for small-molecule analysis and property prediction.
  
• Apply statistical, cheminformatics, and machine learning methods to improve hit identification and hit-to-lead processes.
  
• Collaborate with chemistry and research teams to integrate AI/ML and cheminformatics into DMTA workflows.
  
• Enhance databases and computational pipelines to support data-driven research.
  
• Develop computational tools, visualizations, and analytical programs for molecular data analysis.
  
• Communicate scientific insights across teams and support collaboration.
  
• Provide mentoring and promote best practices in data integrity, reproducibility, and FAIR data principles.
  

Your Professional Profile Includes

• 
  
• PhD or Master's degree in Cheminformatics, Computational Chemistry, Chemistry, or a related discipline.
  
• Expertise in structure-based drug design (SBDD), including docking, pharmacophore modeling, virtual screening, and molecular dynamics.
  
• 3+ years of experience with ligand-based modeling (QSAR, 2D/3D virtual screening) and protein modeling (e.g., homology modeling, protein-protein docking).
  
• Data science and statistical analysis skills, including exploratory data analysis and model validation.
  
• Advanced programming skills in Python or R, plus proficiency in an additional language, following coding best practices.
  
• Experience with cheminformatics tools (e.g., RDKit, OpenEye) and molecular analysis techniques such as library enumeration, similarity analysis, clustering, and dimensionality reduction.
  
• Industry familiarity with SQL/databases, analytics tools (KNIME, Spotfire, Shiny), and NLP/LLMs in scientific contexts; relevant industry experience.
  

Compensation and Benefits

The established salary range for this position is $80,000-120,000k, depending on individual qualifications and experience. Employees receive medical, dental, and vision coverage, along with a high-matching 401(k) retirement plan.

#LI-Onsite

At Givaudan, you contribute to delightful taste and scent experiences that touch people's lives.
You work within an inspiring teamwork culture - where you can thrive, collaborate and learn from other talented and passionate people across disciplines, regions and divisions.
Every essence of you enriches our world.
Diversity of perspectives fuels innovation and fosters deeper connections with our employees, customers, and partners. At Givaudan, we are dedicated to cultivating an inclusive environment where every individual's voice is valued and has the power to shape our world. Join us in making a difference together.

Role Title - Quality Control Analyst III, Analytical

Department- QC

Reports to- QC Manager, Analytical

FLSA -Exempt

Salary Range: $80k- $90k

CORE VALUES

Respect ● Passion ● Teamwork ● Integrity ● Honesty ● Commitment ● Collaboration

COMPANY DESCRIPTION

Polaris Pharmaceuticals, Inc., an affiliate of the Polaris Group ( ), is a therapeutic protein drug manufacturer located in Vacaville, California. Polaris has a cGMP facility producing biological study drugs to support all Polaris Group clinical trials at various stages in the USA, Europe, and the Asian-Pacific region.The lead project of the company is now in clinical trials for patients with different types of cancer including mesothelioma, sarcoma, and glioblastoma. Polaris is seeking candidates to help with the production of this protein drug as well as the production of products for our clients and partners.

ROLE SUMMARY

The Quality Control Analyst, under direct or minimal supervision, is responsible for performing biochemical, physical, and chemical evaluations of process development, lot release, and stability samples compliant with cGMP guidelines. The Analyst works independently on assays that he/she has mastered. This position requires willingness to undergo training on more advanced analytical methods and always employs laboratory safety policies. The Analyst will be responsible for the timely completion of assignments. Good record keeping, organizational, written, and verbal communication skills are essential. The analyst must be willing to work overtime as required.

ROLE RESPONSIBILITIES

• Performs, under direct or minimal supervision, biochemical/physical/chemical analyses of test samples under cGMP to meet specified timelines.
• Reviews test data for accuracy, data integrity, system suitability, and conformance against defined criteria/specifications.
• Provides technical support with troubleshooting of test methods, as needed.
• Identify and contribute to OOS/OOE/OOT investigations related to testing performed.
• Initiate and author deviation and laboratory investigations.
• Maintains the laboratory in an inspection-ready state.
• Develops and maintains proficiency in a broad range of trained test methods.
• Train analysts on test methods and procedures.
• Responsible for authoring Change Control records and leading the revision of written procedures as assigned.
• Holds self and others responsible to abide by department and company policies and practices.
• Adheres to cGMP, 21CFR, USP, EP, ICH, and other applicable regulatory requirements.
• Manage reagent and equipment inventory for assigned areas of responsibilities.
• Responsible for sampling and testing of incoming raw materials

SKILLS

• Strong working knowledge of cGMP regulations, including 21CFR 210 & 211, USP, EP, and ICH.
• Ability to follow written instructions and to perform tasks with direct or minimal supervision.
• Works independently as well as in a team environment.
• Familiarity with use of a computer: e.g., Proficient in Windows, Microsoft Word, Excel.
• Good written, verbal, and communication skills.
• Strong documentation skills a must. The analyst must develop skills in the operation and routine maintenance of various analytical instruments and computers.

The analyst must develop the skills necessary to understand the operation of the equipment and gain knowledge of the equipment used for testing and to use these skills in the event of an unexpected result caused by equipment or reagent failure that warrants a laboratory investigation. Experience with Protein analytics, SDS-PAGE, separations technology for HPLC, Chromatography Data Systems (CDS) software such as OpenLab, subvisible particles testing (USP ), and CCIT preferred. The employee must occasionally lift and/or move up to 25 pounds. Specific vision abilities by this job include close vision, depth perception and ability to adjust focus.

QUALIFICATIONS

B. S./B. A. in Science/Related Field (major in biology-biochemistry-chemistry). Minimum of 5 years of relevant laboratory experience is desired.