Engineering Jobs in Charlestown

Salary Range: $90,000k- $115,000 (depending on experience)

Vaxess is developing a pipeline of next-generation therapeutics on our novel micro-array patch platform. With only five minutes of wear-time on the skin, the Vaxess’ patch combines room temperature stability with simplified application to dramatically alter the way that drugs are delivered. Vaxess is committed to enabling products that are not only more effective, but also more accessible to patients around the world.

Research & development at Vaxess is cross-disciplinary, integrating mechanical, industrial, biomedical, and chemical engineering with chemistry, biology, and human factors to address important unmet medical needs. We are seeking a talented, collaborative, and highly motivated engineer to join our growing team. This role offers a unique opportunity to build manufacturing capacity from the ground up to bring innovative technology to the global vaccine and therapeutic market.

Responsibilities:

• Characterize and improve manufacturing process unit operations by designing, executing, and analyzing process development experiments; communicate results via written reports and oral presentations to internal and project teams
• Support manufacturing scale-up by assessing novel equipment, work flows, analytical techniques/PAT, and process configurations
• Support manufacturing operations by incorporating equipment and process improvements within established processes and equipment trains, and by revising manufacturing batch records, SOPs, and other controlled documents to reflect changes; contribute to implementing and maintaining Vaxess’ Quality System.
• Supervise and mentor junior engineer(s) and technicians, including a direct report
• Collaborate closely with cross-functional teams to support product development and manufacturing activities

Qualifications:

• BS in Mechanical Engineering, Biomedical Engineering, or a related discipline
• 2 – 7 years of relevant direct R&D experience within the medical device or biopharmaceutical industries; experience working on combination products is highly desirable
• Demonstrated success using empirical and first-principles models to inform and analyze experiments; experience with statistical methodologies and working with large data sets (e.g. Six Sigma, DoEs, multivariate techniques) is a plus
• Excellent time and project management skills and proven ability to meet goals and deadlines
• Demonstrated abilities to learn new skills and fields, creatively solve challenging technical problems, think independently, and work collaboratively in diverse multidisciplinary teams
• Entrepreneurial spirit and drive to positively impact global human health

At Vaxess, we’re bringing together exceptional talent to drive our product development forward. We value collaboration, curiosity, and a dynamic work environment. To apply, please submit your CV/resume to

Job Title: Application Analyst II - EPIC Beaker AP

Location: Boston, MA (Remote)

Duration: 9+ Months

Hybrid position, remote with travel on-site at Client for kick-off and important milestone meeting, about once/month

Job Description

The Beaker AP Analyst should have the Epic Beaker AP certification as a requirement along with prior AP Beaker full cycle implementation experience.

The analyst position does not require PMP certification.

The analyst will be responsible for workflow analysis, Beaker AP build, validation testing, preparing for and supporting go-live of Beaker AP.

Position summary:

• The Applications Analyst II is a business specialist and technology generalist responsible for aligning technology solutions with business strategies.
• The Applications Analyst II is responsible for proactively identifying opportunities to apply technologies to business processes by informing and advising customers on information system technologies' functionality, costs, benefits, and implementation requirements.
• The Applications Analyst II functions as technical liaison and broker of services with various vendors.
• The Applications Analyst II must develop and maintain credibility and effective working relations with both customer management and IT personnel.
• The Applications Analyst II must demonstrate an understanding of business problems, as well as IT strategies, issues, and priorities.
• This position requires forward-thinking individuals who seek opportunities to apply technology to improving business processes within strategic system goals.

JOB REQUIREMENTS

EDUCATION

Associate's degree (or equivalent combination of formal education and experience). Bachelor's degree preferred.

EXPERIENCE:

• Requires at least 2 + years relevant experience in either of the following: Business systems analysis, preferably across multiple hardware and software platforms or
• Business unit experience that includes working closely with IT in the development and implementation of systems.

Knowledge and skills:

• Knowledge of the assigned business area's products and processes.

• Strong technical knowledge and ability to express complex technical concepts in terms that is understandable to the business.

•Understanding of project management concepts in planning and implementing multiple projects in a cross functional environment.

• Strong written communication skills, including project documentation and technical writing.

•Strong verbal communication skills while interacting with team members, other teams in the IT department, end users, and/or other departments throughout the organization

•Strong analytical and conceptual skills; a demonstrated track record in new concept development for various projects and complex technical plans.

• Ability to solve problems often spanning multiple environments in a business area.

• Understanding of how IT affects an organization and ability to link it to redesigned business process

• Ability to be a team player; flexible, friendly, congenial, and enthusiastic.

• Proficiency in Microsoft Office products.

Epic Analysts:

• Epic's Beaker AP certification required.

Additional experience desired:

• Previous experience in business process re-engineering or process improvement is desirable, involving broad-based information systems and utilizing tools and techniques to effect business change.
• Experience in the strategic use of technology in managing and growing a business.
• Experience in organizing, planning, and executing projects from vision through implementation, involving internal personnel, contractors, and vendors.
• HL7 knowledge is a plus

Immediate need for a talented Scientist I. This is a 12+ Months contract opportunity with long-term potential and is located in Waltham, MA, USA(Onsite). Please review the job description below and contact me ASAP if you are interested.

Job Diva ID: 26-08545

Pay Range: $ 46-$56 /hour. Employee benefits include, but are not limited to, health insurance (medical, dental, vision), 401(k) plan, and paid sick leave (depending on work location).

Key Responsibilities:

• Develop and optimize robust viral/non-viral vector purification process using advanced knowledge of column chromatography, filtration, and other downstream purification technology
• Lead and conduct viral/non-viral vector purification process development and process analytics
• Develop and optimize robust viral/non-viral vector purification process using advanced knowledge of column chromatography, filtration, and other downstream purification technology
• Develop, conduct, maintain analytical assays such as ELISA, DLS, Octet, QPCR/ddPCR, HPLC, and CE-SDS etc. for in-process sample testing to support process development
• Provide scientific and technical expertise for in-process sample testing activities, including product quality and process impurity methodologies
• Perform troubleshooting experiments and communicate findings with appropriate working groups
• Maintain industry knowledge and keep abreast of new and relevant technologies
• Perform data analysis, contribute to technical reports, external publications, patent applications and internal/external presentations
• Lead scale-up activities to implement a manufacturing process based on DSP development knowledge
• Communicate effectively with internal and external teams, e.g. CDMOs for tech transfer activities
• Mentor and support junior staff and build a culture of support and collaboration

Key Requirements and Technology Experience:

• Key skills: - Purification experience/ Protein Purification Chromatography
• Technical experience in modern analytical techniques such as spectrophotometry, ELISA, DLS, - Late-stage purification experience such as design space mapping and process robustness studies
• PhD in Biotechnology, Biochemistry, Chemical Engineering or related discipline or master’s degree with a minimum of 4 years of relevant experience or a bachelor’s degree with a minimum of 6 years of relevant experience
• Technical experience in modern analytical techniques such as spectrophotometry, ELISA, DLS, Octet, QPCR/ddPCR, HPLC, and CE-SDS
• Significant experience, knowledge and understanding of purification technologies and operations such as:
• Filtration unit operations at various scales, including depth filtration, tangential flow filtration, etc.
• Protein purification chromatography
• Virus clearance and inactivation
• Familiarity with advanced purification technologies and process analytical technologies
• Familiarity with analytical method transfer, analytical method bridging across organizations
• Experience with process technology transfers and performing gap analyses and risk assessments
• Understanding of critical quality attributes and the principles of Quality by Design and ability to apply DOE to downstream development
• Expertise in technical report writing
• Experience in AAV and/or non-viral purification development
• Experience in writing CMC components of regulatory dossiers
• Knowledge of product comparability, target product profile and quality risk assessment activities
• Viral clearance study design and execution
• Late-stage purification experience such as design space mapping and process robustness studies
• Ability to work in Biosafety Level 2, follow safe lab procedures and maintain good laboratory practices (GLPs)
• Ability to work under minimal supervision and function within a collaborative, team-oriented environment
• Excellent organization and communication skills
• Innovative, critical and creative thinker, unafraid of proposing aggressive solutions to complex problems
• Experience with biophysical characterization
• Experience in continuous manufacturing and process analytical technology
• Experience in mentoring junior staff
• Ability to build and nurture cross-functional relationships
• Ability to communicate and represent group in diverse, multi-functional meetings

Our client is a leading Pharmaceuticals industry , and we are currently interviewing to fill this and other similar contract positions. If you are interested in this position, please apply online for immediate consideration

Pyramid Consulting, Inc. provides equal employment opportunities to all employees and applicants for employment and prohibits discrimination and harassment of any type without regard to race, colour, religion, age, sex, national origin, disability status, genetics, protected veteran status, sexual orientation, gender identity or expression, or any other characteristic protected by federal, state, or local laws.

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Experience you will need:

• Ability to read and interpret construction drawings and specifications.
• Understanding of construction methods and materials.
• Proficiency in Excel and spreadsheets.
• Familiarity with CAD software preferred.
• Strong written and verbal communication skills.
• Degree in Construction Management, Engineering, Architecture, or related field preferred.
• Prior construction or estimating experience required.
• 7+ years of experience in Commercial Construction Estimating preferred.
• Minimum 3+ years estimating experience considered.

Date Posted:

Country:

Location:

Position Role Type:

U.S. Citizen, U.S. Person, or Immigration Status Requirements:

Security Clearance:

At Raytheon, the foundation of everything we do is rooted in our values and a higher calling – to help our nation and allies defend freedoms and deter aggression. We bring the strength of more than 100 years of experience and renowned engineering expertise to meet the needs of today’s mission and stay ahead of tomorrow’s threat. Our team solves tough, meaningful problems that create a safer, more secure world.

The Systems Engineering, Integrated Systems Department is seeking a Systems Engineering Technical Lead for the NASAMS product line. This role requires strong technical expertise and engineering leadership skills to drive the design and development of world-class air and missile defense systems.

The Integrated Systems Department supports Raytheon by providing world-class weapon systems engineering. Domain expertise includes radar systems, effector systems, battle management, command and control, network design, battlespace integration, and interoperability for both domestic and international customers.

You will work alongside motivated engineers who are responsible for conducting systems engineering studies and trades; supporting system requirements definition and analysis; and contributing to algorithm development, integration, test, and evaluation.

What You Will Do

• Provide technical oversight and management for a variety of Systems Engineering efforts

• Concept and requirements development (including decomposition and flowdown) within a mature product-line

• Concept of Operations (CONOPS) development and design

• Algorithm optimization and development

• Multi-disciplinary development efforts across the kill-chain for an Air and Missile Defense System

• Collaboration with customer to bring new capabilities to the warfighter

• Functional analysis of real world and test data; trade studies to bring advanced features to fielded system

• Support and lead Internal and External Program and Design Reviews

• Collaborate with other IPT/CPT leads from the various functions and products

• Support and lead Internal Research and Development for future capability upgrades

• System integration and test support, including live fire test events

• Periods of travel up to 25% of time both domestically and internationally

Qualifications You Must Have

• Typically requires a degree in Science, Technology, Engineering or Mathematics (STEM) and a minimum of 8 years of prior relevant experience

• Experience with Air Defense Systems in systems engineering roles supporting development or production

• Experience with managing budget, scope and/or earned value

Qualifications We Prefer

• Experience interfacing with external customers and industry partners

• Excellent communication skills, written and verbal, with a variety of audiences

• Self-motivated, passionate leader

• 5+ years of experience in Air Defense Systems, Systems Engineering production or development

• Existing DoD Security Clearance

• Knowledge of Air Defense systems (examples – Patriot and NASAMS Systems)

• Experience managing competing programmatic priorities

• Experience making challenging technical decisions

• Familiarity with the Raytheon Integrated Product Development System (IPDS) or equivalent

• Experience with Earned Value Management (EVM) (plus, experience with Raytheon execution of EVM)

• Advanced degree in EE, CE, Physics, Math, ME, Aerospace\

What We Offer

• Our values drive our actions, behaviors, and performance with a vision for a safer, more connected world. At RTX we value: Safety, Trust, Respect, Accountability, Collaboration, and Innovation.

• Relocation assistance is available

Learn More & Apply Now!

Please consider the following role type definition as you apply for this role.

• Onsite: Employees who are working in Onsite roles will work primarily onsite. This includes all production and maintenance employees, as they are essential to the development of our products.

Clearance Information: This position requires a security clearance. DCSA Consolidated Adjudication Services (DCSA CAS), an agency of the Department of Defense, handles and adjudicates the security clearance process. More information about Security Clearances can be found on the US Department of State government website here: part of our commitment to maintaining a secure hiring process, candidates may be asked to attend select steps of the interview process in-person at one of our office locations, regardless of whether the role is designated as on-site, hybrid or remote.

RTX is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, age, disability or veteran status, or any other applicable state or federal protected class. RTX provides affirmative action in employment for qualified Individuals with a Disability and Protected Veterans in compliance with Section 503 of the Rehabilitation Act and the Vietnam Era Veterans’ Readjustment Assistance Act.

Privacy Policy and Terms:

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Location: New York, Boston, Chicago, Atlanta, Hoboken, Philadelphia, McLean, Seattle

At EY, we’re all in to shape your future with confidence.

We’ll help you succeed in a globally connected powerhouse of diverse teams and take your career wherever you want it to go. Join EY and help to build a better working world.

EY-Parthenon’s unique combination of transformative strategy, transactions and corporate finance delivers real-world value – solutions that work in practice, not just on paper. Benefiting from EY’s full spectrum of services, we’ve reimagined strategic consulting to work in a world of increasing complexity.

With deep functional and sector expertise, paired with innovative AI-powered technology and an investor mindset, we partner with CEOs, Boards, Private Equity and Governments every step of the way – enabling you to shape your future with confidence.

As a Director with EY-Parthenon's Strategy and Execution Commercial Strategy practice, you will be a vital member of the team leading and executing strategy development, transactions, and turn-arounds for our clients. You\'ll collaborate with our EY-Parthenon team members to realize improved returns for clients by identifying and unlocking value through improvements in corporate/BU strategy, go-to-market strategy (including digital), commercial operating model, and optimization of the commercial functions (sales, service, marketing, pricing), while minimizing customer disruption. You will identify, define, quantify, and realize sustainable value through revenue enhancement and cost and margin improvement tied to the commercial aspects of the clients’ business. You will also focus on business and practice development as well as developing team members to achieve their career goals.

• Project Management – manage project teams comprising of colleagues from across EY-Parthenon to successful project execution.

• Business and Commercially Driven – work effectively in a fast-paced, exciting environment with strong business acumen to drive value to our clients.

• Business Development - assist in aspects of pursuits, including presentations and client meetings. Contribute to our practice development initiatives, supporting the continued focus on our team as a great place to work.

• People Development – coach, mentor, and develop team members to enable achievement of their career goals.

• Building Relationships - Strong working relationships with clients, including influencing, advising, and supporting key decision makers.

• Innovation – Develop and support thought leadership and intellectual capital.

• A bachelor’s degree in Business, Accounting, Finance, Engineering, Computer Science, or Analytics and 5 years of related work experience; or a graduate degree and 3 years of related work experience.

• MBA is preferred.

• Significant transactions (buy and/or sell side) management consulting experience.

• Experience in the following:

• Corporate and/or BU strategy development.

• Commercial functions (e.g., sales, marketing, customer service, pricing).

• Go-to-market strategy and revenue synergy design/capture for traditional, digital and hybrid commercial models.

• Evaluation of market landscape including market size, competition, market trends and resulting commercial implications.

• Pre-deal strategy including growth assessments (e.g. profitability assessments, clean room, etc.).

• Experience leading and managing in complex business environments.

• Excellent negotiation and influencing skills, and the ability to develop long-lasting relationships both internally and externally.

• The ability and willingness to travel and work in excess of standard hours when necessary.

• A proven record of excellence in a transactions and/or commercial strategy role.

• Experience gained within another large professional services organization.

• Knowledge of how to leverage AI tools in a business setting, including Microsoft Copilot.

• Established networking skills in a relevant industry.

At EY, we’ll develop you with future-focused skills and equip you with world-class experiences. We’ll empower you in a flexible environment, and fuel you and your extraordinary talents in a diverse and inclusive culture of globally connected teams. Learn more .

• We offer a comprehensive compensation and benefits package where you’ll be rewarded based on your performance and recognized for the value you bring to the business. The base salary range for this job in all geographic locations in the US is $205,000 to $235,000. Individual salaries within those ranges are determined through a wide variety of factors including but not limited to education, experience, knowledge, skills and geography. In addition, our Total Rewards package includes medical and dental coverage, pension and 401(k) plans, and a wide range of paid time off options.

• Join us in our team-led and leader-enabled hybrid model. Our expectation is for most people in external, client serving roles to work together in person 40-60% of the time over the course of an engagement, project or year.

• Under our flexible vacation policy, you’ll decide how much vacation time you need based on your own personal circumstances. You’ll also be granted time off for designated EY Paid Holidays, Winter/Summer breaks, Personal/Family Care, and other leaves of absence when needed to support your physical, financial, and emotional well-being.

Are you ready to shape your future with confidence? Apply today.

EY accepts applications for this position on an on-going basis.

For those living in California, please click here for additional information.

EY focuses on high-ethical standards and integrity among its employees and expects all candidates to demonstrate these qualities.

EY | Building a better working world

EY is building a better working world by creating new value for clients, people, society and the planet, while building trust in capital markets.

Enabled by data, AI and advanced technology, EY teams help clients shape the future with confidence and develop answers for the most pressing issues of today and tomorrow.

EY teams work across a full spectrum of services in assurance, consulting, tax, strategy and transactions. Fueled by sector insights, a globally connected, multi-disciplinary network and diverse ecosystem partners, EY teams can provide services in more than 150 countries and territories.

EY provides equal employment opportunities to applicants and employees without regard to race, color, religion, age, sex, sexual orientation, gender identity/expression, pregnancy, genetic information, national origin, protected veteran status, disability status, or any other legally protected basis, including arrest and conviction records, in accordance with applicable law.

EY is committed to providing reasonable accommodation to qualified individuals with disabilities including veterans with disabilities. If you have a disability and either need assistance applying online or need to request an accommodation during any part of the application process, please call 1-800-EY-HELP3, select Option 2 for candidate related inquiries, then select Option 1 for candidate queries and finally select Option 2 for candidates with an inquiry which will route you to EY’s Talent Shared Services Team (TSS) or email the TSS at

Bioinformatics Scientist – Antibody Discovery

A growing global veterinary pharmaceuticals organisation is looking for a Bioinformatics Scientist to support antibody discovery programmes for companion animals (dogs, cats, horses).

Working closely with senior R&D leadership, this role will focus on applying bioinformatics, sequencing data analysis and protein modelling to identify and optimize therapeutic antibody targets.

Key Responsibilities

• Analyse genomic, DNA-seq and RNA-seq datasets to support antibody discovery
• Apply bioinformatics and modelling approaches to evaluate and optimize antibody candidates
• Contribute to protein modelling and in-silico antibody engineering (e.g. liability remediation, biophysical optimization)
• Curate and integrate genomic datasets for companion animal species
• Collaborate closely with discovery biology and R&D teams

Key Requirements

• At least 1 year of experience working with therapeutic antibodies (essential)
• Experience analyzing next generation sequencing datasets (DNA / RNA-seq)
• Background in bioinformatics, computational biology or structural biology
• Familiarity with protein modelling / antibody engineering tools (e.g. MOLE, Rosetta or similar)
• Strong communication skills and ability to work cross-functionally with scientific teams

This is an exciting opportunity to contribute to cutting-edge biologics discovery in animal health, helping develop next-generation therapies for companion animals.

If interested, please reach out for a confidential discussion.