Ctcf Protein Jobs in Usa

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• Plan and execute assigned on-site experiments in support of Process Development activities and project goals.
  
• Select appropriate experimental methods and techniques based on project requirements.
  
• Analyze and interpret experimental data, evaluate data quality, and identify anomalous results.
  
• Recommend alternative approaches, research new methods and techniques, and proactively consult senior team members to resolve technical challenges.
  
• Participate in group meetings and present experimental results, data interpretation, and conclusions.
  
• Demonstrate strong verbal communication and interpersonal skills, including the ability to clearly explain experimental processes and outcomes.
  
• Work collaboratively with a team-oriented, problem-solving mindset.
  
• Consistently follow safety practices; ability to work with highly potent compounds upon appropriate training.
  

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• Bachelor's or higher degree in Chemical Engineering, Biochemical Engineering, Biochemistry, Chemistry, or a related scientific discipline.
  
• Prior experience in biologics purification, with emphasis on conjugation, tangential flow filtration (UF/DF), and filtration.
  
• Experience with analytical techniques such as SEC/HPLC, capillary electrophoresis (reducing/non-reducing), and HCP testing is beneficial but not required.
  
• Knowledge of cGMPs, technology transfer, and bioprocess scale-up.
  
• Strong technical writing skills.
  
• Ability to work effectively in cross-functional and multidisciplinary teams.
  
• Working knowledge of downstream process development, including centrifugation, normal and tangential flow filtration, chromatography operations, and virus clearance, with hands-on experience in several areas expected.
  
• Experience with multiple biologic modalities (e.g., monoclonal antibodies, bispecifics, fusion proteins, antibody-drug conjugates, virus particles) and expression systems (microbial and mammalian) is a plus.
  
• Ability to design and execute purification experiments with increasing independence to support process definition, optimization, and characterization.
  
• Collaborate with Technical Operations during technology transfer from process development to GMP manufacturing, including on-floor support, troubleshooting, and identification of process and equipment improvements.
  
• Contribute to regulatory filings, process validation, and characterization reports.
  
• Self-motivated, well-organized, and intellectually curious, with interest in scientific literature and conferences.
  

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• BS degree in a relevant scientific discipline with 2+ years of relevant experience, OR
  
• MS degree in a relevant scientific discipline with 0+ years of relevant experience
  

Creighton University in Omaha, NE is seeking to hire a Postdoctoral Research Fellow in the Translational Hearing Center in the Biomedical Sciences Department.

The laboratory focuses on two main lines of research. The first involves studying Usher proteins and their interactions with transmembrane receptors during inner ear development. This research includes developing genetically modified mouse models to analyze morphology, function, and transcript/protein profiles under both basal and stress conditions.

The second line of research aims to identify therapies for acquired hearing loss. We use zebrafish and mammalian models to study hearing loss caused by noise, cisplatin, and aminoglycosides.

Our lab offers an excellent research environment, fostering the exchange of new ideas and exploration of novel directions. Additionally, there are opportunities to apply for both intramural and extramural small grants.

This is a grant funded position.

Qualifications

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• Doctoral Degree in related area
  
• 1+ years of experience in the hearing field and the ability to learn essential techniques such as hearing/vestibular tests, microdissection, and imaging
  

How to Apply

Applicants are encouraged to apply with a cover letter and up to date resume attached to the online application. If you have any questions submitting your application or materials, please don't hesitate to contact

Open date: October 4, 2025

Next review date: Wednesday, Mar 18, 2026 at 11:59pm (Pacific Time)

Apply by this date to ensure full consideration by the committee.

Final date: Wednesday, Mar 18, 2026 at 11:59pm (Pacific Time)

Applications will continue to be accepted until this date.

The He lab is in the Molecular and Cell Biology department at UC-Berkeley, which encompasses a breadth of disciplines spanning all levels of organization and encompassing diverse organisms. The breath of training, combined with the unique location of Berkeley in the center of biomedical research, offer a nurturing environment for the next-generation scientist to launch on a successful career in biomedical research in academia and industry. The Principal Investigator, Dr. Lin He, was awarded the MacArthur Fellowship (the genius award), the Searle Scholar, a HHMI Faculty Scholar, and is currently a Thomas and Stacey Siebel distinguished chair professor at UC-Berkeley, and a biohub investigator with the Chan-Zuckerberg Initiative (CZI).

The developmental and physiological complexity of a given organism is not governed by the sheer number of protein-coding genes. In mammals, the numerous functional non-coding elements greatly expand gene regulatory modality and diversify functional reservoir. Using human genetics/genomics, mouse genetics/genomics, cell and molecular biology approaches, the He lab at UC-Berkeley has identified a variety of functional non-coding elements, including transposons and non-coding RNAs. Not only do non-coding elements offer important developmental/physiological functions, they also provide us with a unique angle to discover new biological/cellular processes in development and disease. Combining sophisticated genome engineering and innovative live cell imaging, we have pioneered in vivo studies to elucidate the new cellular functions and molecular mechanisms in development and aging. The discoveries of the He lab have been well recognized by publications in prestigious journals, including Nature, Science and Cell. Currently, there are postdoc openings in two projects.

Transposons in mammalian preimplantation development ~40% of mammalian genome originates from transposons, whose abundance greatly exceeds that of protein genes. While historically viewed as degenerated "parasitic" DNAs, transposons yield numerous functional elements for the host genome. These sequences resulted from ancient invasion confer new mechanisms of gene regulation, generate Neogene/ncRNA functions, and provide raw material for genome innovation. Mammalian preimplantation embryos constitute one of the best systems to study transposon-host interactions, as ~20% of their transcriptome results from transposon induction. We aim to characterize the role of specific transposons in preimplantation embryos.

Transposons in aging and disease While specific transposons are integral components of host biology, most mammalian transposons are potentially detrimental to the host genomes, thus inactivated via degenerative mutations and/or transcriptional/post-transcriptional silencing. Interestingly, aberrant transposon induction has been observed in a variety of pathological conditions, including aging, cancer and infection. We aim to investigate the mechanisms underlying transposon dysregulation during reproductive aging and cancer, and to elucidate the effects of transposon-host interactions that accelerate aging and promote cancer.

Postdoc responsibilities:

1) The postdoc will work with the PI to develop a project in one of the two research directions, to comprehensively read literature, to establish appropriate experimental systems, to learn important technologies, and to execute experiments to advance the project and perform data analyses.

2) The postdoc will meet with the PI on a weekly basis to discuss results, to development experimental plans.

2) The postdoc will work with junior lab members to mentor them on specific experimental techniques .

3) The postdoc will contribute to lab duties, which is evenly distributed among all lab members.

Lab:

PhD (or equivalent international degree) or enrolled in a PhD degree program (or equivalent international degree)

Ph.D. (or equivalent international degree) required by the appointment start date. No more than three years of post-degree research experience by the start date.

Ph.D. in developmental biology, Genetics, Genomics, Cell Biology, Molecular Biology, Biochemistry or related field are all welcome to apply. Prior research experiences in mammalian development and disease are preferred.

• Curriculum Vitae - Your most recently updated C.V.

  
  

• Cover Letter

  
  

• Research Statement - Please discuss research accomplishments and proposed plans. This can include, for example, your publication record, awards, presentations, inclusive research practices that promote the excellence of your research, and areas for future research.
  
  (Optional)

  
  

• 3-5 required (contact information only)

Help contact:

UC Berkeley is committed to diversity, equity, inclusion, and belonging in our public mission of research, teaching, and service, consistent with UC Regents Policy 4400 and University of California Academic Personnel policy (APM 210 1-d). These values are embedded in our Principles of Community, which reflect our passion for critical inquiry, debate, discovery and innovation, and our deep commitment to contributing to a better world. Every member of the UC Berkeley community has a role in sustaining a safe, caring and humane environment in which these values can thrive.

The University of California, Berkeley is an Equal Opportunity employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, age, or protected veteran status.

For more information, please refer to the University of California's Affirmative Action and Nondiscrimination in Employment Policy and the University of California's Anti-Discrimination Policy.

In searches when letters of reference are required all letters will be treated as confidential per University of California policy and California state law. Please refer potential referees, including when letters are provided via a third party (i.e., dossier service or career center), to the UC Berkeley statement of confidentiality prior to submitting their letter.

As a University employee, you will be required to comply with all applicable University policies and/or collective bargaining agreements, as may be amended from time to time. Federal, state, or local government directives may impose additional requirements.

Unless stated otherwise, unambiguously, in the position description, this position does not include sponsorship of a new consular H-1B visa petition that would require payment of the $100,000 supplemental fee.

As a condition of employment, the finalist will be required to disclose if they are subject to any final administrative or judicial decisions within the last seven years determining that they committed any misconduct.

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• "Misconduct" means any violation of the policies or laws governing conduct at the applicant's previous place of employment, including, but not limited to, violations of policies or laws prohibiting sexual harassment, sexual assault, or other forms of harassment or discrimination, as defined by the employer.
  
• UC Sexual Violence and Sexual Harassment Policy
  
• UC Anti-Discrimination Policy
  
• APM - 035: Affirmative Action and Nondiscrimination in Employment
  

Who We Are

Brami is democratizing the Italian “good life” by redefining Italian food for the modern pantry. 

Founded by Aaron Gatti, a first-generation Italian American inspired by family roots in Umbria and time in a Michelin-star kitchen, Brami centers its current product lineup on the ancient lupini bean—a Mediterranean superfood cherished for centuries. We offer two Made-in-Italy lines: Italian Protein Pasta (bronze-die extruded; just two ingredients—premium Italian durum semolina and whole-milled lupini flour; ~70% more protein, 25% fewer net carbs, and 3× the fiber vs. typical pasta) and snackable lupini beans cured in savory spices. Headquartered in the U.S., Brami is the #1 fastest-growing pasta brand in the country two years running, available online and in 5,000+ stores nationwide.

Responsibilities:

Supply Chain Execution

• Manage purchase orders, production schedules, and day-to-day communication with co-manufacturers and suppliers
• Track production timelines and escalate risks or delays proactively

Inventory & Fulfillment

• Maintain accurate inventory levels across 3PLs and warehouses
• Monitor inventory movement, aging, shortages, and discrepancies
• Coordinate inbound and outbound shipments to support retail, wholesale, and DTC fulfillment

Logistics & 3PL Management

• Serve as the primary operational contact for 3PLs
• Manage freight coordination, delivery tracking, and issue resolution
• Ensure SLAs, routing guides, and operational requirements are followed

Operational Reporting

• Prepare and maintain weekly operational reports (inventory, fill rates, OTIF, production status)
• Flag risks, constraints, and execution gaps with recommended actions
• Support month-end inventory and COGS reconciliation in partnership with finance

Process & Systems Support

• Document and maintain SOPs for core operational workflows
• Support ERP, inventory system, and EDI execution (transactions, accuracy, data hygiene)
• Identify inefficiencies and recommend process improvements

Cross-Functional Coordination

• Partner with Sales, Marketing, and Customer Experience to support promotions, launches, and customer needs
• Support new SKU launches from an execution and readiness standpoint
• Assist with audits, compliance documentation, and vendor setup

Qualifications

• 3–6+ years of operations, supply chain, or logistics experience (CPG required)
• Experience working with co-manufacturers, suppliers, and 3PLs
• Strong execution, follow-through, and attention to detail
• Comfortable operating within defined plans while managing day-to-day variability
• Strong Excel / Google Sheets skills; ERP experience required, Netsuite preferred
• Experience supporting EDI execution in a CPG or retail environment

Are you looking to work on cutting-edge science with real-world impact? This is a unique opportunity to join an innovative, fast-growing startup developing sustainable protein and next-generation biomaterials. You’ll work alongside passionate, forward-thinking leaders in a collaborative, high-energy environment—while gaining hands-on experience with advanced molecular biology and strain engineering techniques.

If you’re excited by breakthrough science, sustainability, and the chance to make a tangible impact early in your career, this role is for you.

What You’ll Do

• Design and execute molecular biology experiments to engineer fungal strains (gene knockouts, knock-ins, overexpression, gene editing)
• Perform RNA-based workflows including extraction, library prep, sequencing, and data analysis
• Conduct RT-PCR and qPCR for gene expression analysis
• Construct and validate plasmids for gene expression and transformation
• Lead fungal transformation efforts and optimize strain performance
• Characterize engineered strains (growth, metabolic output, stress tolerance, etc.)
• Support small-scale fermentation experiments and high-throughput screening
• Analyze experimental data using statistical and bioinformatics tools
• Maintain detailed documentation and present findings to internal teams

What We’re Looking For

Required:

• Bachelor’s degree in Microbiology, Molecular Biology, Biotechnology, Biochemistry, or related field
• 2+ years of hands-on lab experience in molecular biology (academic or industry)
• Strong experience with:
• RNA sequencing workflows (extraction, library prep, analysis, visualization)
• RT-PCR and qPCR techniques
• Designing and executing genetic modification experiments
• Proven ability to document experiments and communicate results clearly

Preferred:

• Master’s degree in a related scientific field
• Experience working with yeast or fungal systems

Why This Role Stands Out

• Work on groundbreaking applications in sustainable protein and biomaterials
• Be part of a startup environment—fast-paced, collaborative, and full of opportunity to learn
• Gain exposure to advanced molecular techniques and real product development
• Work with engaging, supportive leadership who are invested in your growth
• Contribute to innovative projects shaping industries from food to fashion

Details

• Schedule: Flexible (8:00–4:30 or 9:00–5:30)
• Compensation: $27–$30/hour
• Duration: 6-month contract with potential for extension

General Description:

Supervises staff and executes QC Biochemistry laboratory activities to support GMP manufacturing, testing and release of material, intermediates and finished products under FDA/EU regulations, applicable International Regulations, processes and procedures. Establishes and implements QC Biochemistry procedures and supports regulatory compliance inspections. Ensures efficient and effective day to day operations of the Biochemistry laboratory.

Essential Functions of the job:

• Lead the QC Biochemistry GMP laboratory through late phase activities.
• Oversee QC Biochemistry laboratory related quality systems to ensure conformance with regulations and quality standards.
• Supervise a highly efficient QC Biochemistry team. Identify and develop key talents.
• Manage QC Biochemistry laboratory routine operations, including but not limited to validation, SOP revisions, specification updates, testing records, personnel training and, scheduling, etc.
• Execute laboratory bench work for analytical methods such as Potency assays, Binding ELISA, Cell Culture, Residual Host Cell Protein(HCP), Residual DNA as required.
• Ensure Biochemistry laboratory compliance with Environmental Health and Safety (EHS) standards.
• Ensure timely completion of testing (e.g., in-process, DS release, DP release, and stability testing) to ensure timely generation and reporting of test results In support of manufacturing operations.
• Ensure appropriate investigation of OOS events, discrepancies, lab errors, and equipment failures.
• Implementation of effective corrective actions and preventive actions (CAPAs).
• Participate in internal and external GMP audits where possible.
• Manage QC Biochemistry method transfers and method validation activities, including transfer/validation strategy and approval of protocols and reports.
• Ensure that the QC Biochemistry laboratory meets or improves on budget, cost, volume, and efficiency targets (KPIs) in line with business objectives.
• Manage, motivate, coach and mentor direct reports.
• Undertake any other duties as required.

Core Competencies, Knowledge, and Skill Requirements:

• Scientific degree (ideally in Biochemistry, molecular biology, biotechnology or related).
• Minimum of 5-7 years working experience and 2 years managing laboratory analysts in an FDA-regulated biotechnology, pharmaceutical company with progressive levels of responsibility are required.
• Working knowledge and experience with Biochemistry analytical methods such as Potency assays, Binding ELISA, Cell Culture, Residual Host Cell Protein(HCP), Residual DNA as well as instruments such Incubators, Biosafety Cabinets, Plate Washers, and Microplate Readers, etc.
• Knowledgeable with USP/EP and cGMP/EU GMP regulations.
• Direct experience in a GMP quality control lab is a must.
• Familiar with instrument and equipment validation.
• Expert knowledge of quality control principles, practices, and standards for the biopharmaceutical industry.
• Impressive, demonstrable track record and skills/experience gained within a similar position(s), at a similar level.
• Credible and confident communicator (written and verbal) at all levels.
• Strong analytical and problem-solving ability.
• Excellent project management skills.
• Hands-on approach, with a ‘can do’ attitude.
• Ability to prioritize, demonstrating good time management skills.
• Excellent attention to detail, with the ability to work accurately in a busy and demanding environment.
• Self-motivated, with the ability to work proactively using own initiative.
• Committed to learning and development.

Supervisory Responsibilities:

• Supervise a highly efficient QC Biochemistry team. Identify and develop key talents.
• Manage QC Biochemistry laboratory routine operations, including but not limited to validation, SOP revisions, specification updates, testing records, personnel training and scheduling, etc.
• Manage QC Biochemistry method transfers and method validation activities, including transfer/validation strategy and approval of protocols and reports.
• Ensure that the QC Biochemistry laboratory meets or improves on budget, cost, volume, and efficiency targets (KPIs) in line with business objectives.
• Manage, motivate, coach and mentor direct reports.

Responsible for the dispensing of raw materials liquids and powders (hazardous and non-hazardous), acids/bases, under cGMP conditions to support the manufacture of therapeutic proteins (API)

Individual will be required to perform and monitor all dispensing processes and weighs, including liquid, powder (hazardous and non-hazardous), acids and bases. All processes will be completed per cGMP guidelines to support the manufacture of therapeutic proteins (API).

• Required to attain a basic understanding of cGMP compliance while training under close supervision, demonstrating aseptic technique and cross contamination awareness in handling of products and materials.

• Expected to follow and adhere to all written procedures (SOPs), monitor equipment and processes, perform basic laboratory tasks, including pH, conductivity, and sampling as required. All tasks will be completed while gowned and wearing required PPE while working in a Class C environment.

• Expected to execute process recipes.

• Ability to qualify for all assigned tasks and maintain individual training plan.

• Ability to qualify and perform required functions and scheduled cleans on all Dispensing equipment through routine cleaning and sanitization.

• Perform peer, First Level Reviews of completed eDispense orders/kits, upon completion of WBT and LQM/PM signoff by area trainer.

• Ability to report to production via written and electronic documents in accordance with current good manufacturing practice (cGMP) and good documentation practice (GDPs). Complete documentation reviews as appropriate.

• Prepare materials for transport and delivery to manufacturing suites. Perform material movements both physically and in software systems.

• Participate in Safety Inspections and submit safety observations to provide safer working conditions for self and others.

• Administrative tasks to include attendance at shift exchange and required meetings, sending/receiving of emails, and participation in assigned projects.

• Performs other duties as they are assigned to support Logistics Team.

Associates Degree and/or equivalent experience

Immediate need for a talented Scientist I. This is a 12+ Months contract opportunity with long-term potential and is located in Waltham, MA, USA(Onsite). Please review the job description below and contact me ASAP if you are interested.

Job Diva ID: 26-08545

Pay Range: $ 46-$56 /hour. Employee benefits include, but are not limited to, health insurance (medical, dental, vision), 401(k) plan, and paid sick leave (depending on work location).

Key Responsibilities:

• Develop and optimize robust viral/non-viral vector purification process using advanced knowledge of column chromatography, filtration, and other downstream purification technology
• Lead and conduct viral/non-viral vector purification process development and process analytics
• Develop and optimize robust viral/non-viral vector purification process using advanced knowledge of column chromatography, filtration, and other downstream purification technology
• Develop, conduct, maintain analytical assays such as ELISA, DLS, Octet, QPCR/ddPCR, HPLC, and CE-SDS etc. for in-process sample testing to support process development
• Provide scientific and technical expertise for in-process sample testing activities, including product quality and process impurity methodologies
• Perform troubleshooting experiments and communicate findings with appropriate working groups
• Maintain industry knowledge and keep abreast of new and relevant technologies
• Perform data analysis, contribute to technical reports, external publications, patent applications and internal/external presentations
• Lead scale-up activities to implement a manufacturing process based on DSP development knowledge
• Communicate effectively with internal and external teams, e.g. CDMOs for tech transfer activities
• Mentor and support junior staff and build a culture of support and collaboration

Key Requirements and Technology Experience:

• Key skills: - Purification experience/ Protein Purification Chromatography
• Technical experience in modern analytical techniques such as spectrophotometry, ELISA, DLS, - Late-stage purification experience such as design space mapping and process robustness studies
• PhD in Biotechnology, Biochemistry, Chemical Engineering or related discipline or master’s degree with a minimum of 4 years of relevant experience or a bachelor’s degree with a minimum of 6 years of relevant experience
• Technical experience in modern analytical techniques such as spectrophotometry, ELISA, DLS, Octet, QPCR/ddPCR, HPLC, and CE-SDS
• Significant experience, knowledge and understanding of purification technologies and operations such as:
• Filtration unit operations at various scales, including depth filtration, tangential flow filtration, etc.
• Protein purification chromatography
• Virus clearance and inactivation
• Familiarity with advanced purification technologies and process analytical technologies
• Familiarity with analytical method transfer, analytical method bridging across organizations
• Experience with process technology transfers and performing gap analyses and risk assessments
• Understanding of critical quality attributes and the principles of Quality by Design and ability to apply DOE to downstream development
• Expertise in technical report writing
• Experience in AAV and/or non-viral purification development
• Experience in writing CMC components of regulatory dossiers
• Knowledge of product comparability, target product profile and quality risk assessment activities
• Viral clearance study design and execution
• Late-stage purification experience such as design space mapping and process robustness studies
• Ability to work in Biosafety Level 2, follow safe lab procedures and maintain good laboratory practices (GLPs)
• Ability to work under minimal supervision and function within a collaborative, team-oriented environment
• Excellent organization and communication skills
• Innovative, critical and creative thinker, unafraid of proposing aggressive solutions to complex problems
• Experience with biophysical characterization
• Experience in continuous manufacturing and process analytical technology
• Experience in mentoring junior staff
• Ability to build and nurture cross-functional relationships
• Ability to communicate and represent group in diverse, multi-functional meetings

Our client is a leading Pharmaceuticals industry , and we are currently interviewing to fill this and other similar contract positions. If you are interested in this position, please apply online for immediate consideration

Pyramid Consulting, Inc. provides equal employment opportunities to all employees and applicants for employment and prohibits discrimination and harassment of any type without regard to race, colour, religion, age, sex, national origin, disability status, genetics, protected veteran status, sexual orientation, gender identity or expression, or any other characteristic protected by federal, state, or local laws.

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Ascendo Resources is currently partnering with a fast-growing, privately held food manufacturing company specializing in organic protein products.

Our partner is experiencing sustained double-digit growth and is investing in its supply chain and planning capabilities to support expansion.

We are seeking a hands-on Production Planner who thrives in highly manual planning environments, enjoys building schedules from the ground up, and can confidently manage complexity without relying on automated planning systems.

Role Overview

The Production Planner will own daily and weekly production schedules across refrigerated and frozen manufacturing operations. This role partners closely with inventory, operations, warehouse, quality, and logistics teams to align demand, capacity, raw materials, and execution — while constantly adjusting plans in real time.

Key Responsibilities

• Build and manage daily and weekly production schedules based on demand forecasts, inventory levels, and capacity
• Release and manage production work orders, including BOM accuracy, yields, and labor standards
• Adjust schedules in real time due to downtime, shortages, quality holds, or operational constraints
• Coordinate sequencing to optimize shelf life, freshness, and changeovers
• Ensure raw material, packaging, and consumable availability
• Track planned vs. actual yields; investigate variances and drive corrective actions
• Maintain accurate inventory across raw, WIP, and finished goods with full traceability
• Enforce FIFO / FEFO, lot control, and regulatory requirements
• Build and maintain manual capacity models for labor, lines, and equipment
• Identify bottlenecks and re-plan around downtime and labor constraints
• Support customer fulfillment by validating available-to-ship inventory
• Produce planning, yield, and KPI reporting using Excel, Google Sheets, and BI tools

Systems & Tools

• Advanced Excel & Google Sheets (required – heavy modeling and trackers)
• ERP / MRP systems
• WMS platforms
• CRM and reporting tools (Salesforce, Tableau, Redzone, i3PL, or similar)

Qualifications

• 5+ years of production planning or scheduling experience in food manufacturing
• Meat, protein, or perishable goods experience strongly preferred
• Proven experience planning with and without automated scheduling systems
• Strong understanding of shelf life, yield management, and capacity constraints
• Excellent analytical, organizational, and cross-functional communication skills

Work Environment

• Full-time, on-site role in Pedricktown, NJ
• Exposure to cold or refrigerated production environments as needed
• Occasional schedule flexibility required to support production deadlines

Why Join?

• Competitive base salary + bonus
• Strong benefits and PTO package
• Stable, growth-oriented manufacturing environment
• High-impact role with visibility across operations