Jobs in Natick Massachusetts

Company Description

Variantyx is a technology-driven precision medicine company providing state-of-the-art diagnostic solutions for the rare genetic disorders and reproductive genetics markets, and treatment optimization in oncology. Our proprietary whole genome analysis platform allows us to better understand a person’s genetic makeup, leading to unmatched diagnostic capabilities and improved personalized treatment recommendations.

visit our website: Description

We are seeking an entry-level Specimen Processing Assistant to support our diagnostic laboratory team at our on-site facility in Framingham, MA. This full-time role involves receiving, processing, and organizing biological specimens, ensuring adherence to laboratory protocols and quality standards. Additional responsibilities include maintaining accurate records, utilizing laboratory tools and software, and collaborating with colleagues to streamline workflows and uphold compliance.

Saturday shift coverage needed.

Position Duties & Responsibilities:

• Receive and triage all patient specimens for testing.
• Accession and manage patient information within the LIMS.
• Collaborates with clinical Coordinators to verify missing patient/sample information.
• Biobanking: sorts samples and distributes them to the appropriate storage.
• Maintains designated laboratory equipment.
• Prepares samples for processing.
• Uses various laboratory computer systems for labeling, inquiry, results as needed.
• Disposes of bio-hazardous and chemical waste in the accessioning room.
• Assists with department quality and process improvement projects.
• Sets up supplies for the assigned work area
• Discards specimens as needed.
• Upholds all CLIA, CAP, NYS and other state regulations, as required.
• Call patients to verify and confirm personal information to identify samples
• Ensure accuracy of patient details in the lab's database, and update any discrepancies or changes.
• Update and document patient records in the Salesforce system
• Follow all HIPAA guidelines and confidentiality protocols to protect patient information at all times.

Education & Skills:

• High School degree
• Great organizational skills
• Clear and effective Communication skills
• Multitasking skills
• Must be able to speak/read/write in English
• Detail Oriented

Immediate need for a talented Scientist I. This is a 06+ Months Contract opportunity with long-term potential and is located in Waltham, MA (Onsite). Please review the job description below and contact me ASAP if you are interested.

Job ID:26-08585

Pay Range: $50 - $56/hour. Employee benefits include, but are not limited to, health insurance (medical, dental, vision), 401(k) plan, and paid sick leave (depending on work location).

Key Responsibilities:

• The successful candidate will participate in the development and validation of analytical methods involving cell-based assays, PCR-based assays, and other analytical techniques routinely used to support gene therapy development.
• A strong bioassay background is desired, with a minimum of 2-4 years’ experience in an industry setting performing cell-based assays.
• Molecular biology experience is also a benefit.
• This individual will conduct pre-clinical and clinical lot release and stability testing of viral and non-viral gene therapies.
• This role operates within a cGMP environment and requires excellent verbal and written communication skills, strong attention to detail, and the ability to collaborate effectively with cross-functional departments.
• We are an innovative global healthcare company with one purpose: to chase the miracles of science to improve people’s lives.
• We’re also a company where you can flourish and grow your career, with countless opportunities to explore, make connections with people, and stretch the limits of what you thought was possible. Ready to get started?

Key Requirements and Technology Experience:

• Must Have Skills- Hands-on cell-based assay experience Molecular biology expertise, including PCR Assay development experience
• Nice-to-Have Skills ELISA experience (Enzyme-Linked Immunosorbent Assay) Electronic Lab Notebook (ELN) familiarity Experience working in GxP environments Tools / Platforms ELN ELISA JMP or GraphPad Prism
• Education & Experience Bachelor’s degree + 2–4 years of relevant industry experience Master’s degree + ~2 years of relevant experience PhD not required, but candidates with a PhD will be considered
• Works well independently while possessing strong leadership & communication skills and a demonstrated history of building collaborative, lasting relationships that deliver business results
• Ability to work well in a fast-paced environment and handle multiple priorities successfully
• Ability to work closely with cross functional and other internal teams
• High level of energy, drive, enthusiasm, and commitment with a strong bias for action and prioritization
• Outstanding verbal and written communication skills, as well as demonstrated ability to work confidently and respectfully at all levels of an organization, both internally and externally
• Someone who is highly creative with the ability to think out of the box
• Comfortable working with numbers, metrics & spreadsheets
• Able to influence key partners with ideas that build value.

Our client is a leading Healthcare Industry and we are currently interviewing to fill this and other similar contract positions. If you are interested in this position, please apply online for immediate consideration.

Pyramid Consulting, Inc. provides equal employment opportunities to all employees and applicants for employment and prohibits discrimination and harassment of any type without regard to race, color, religion, age, sex, national origin, disability status, genetics, protected veteran status, sexual orientation, gender identity or expression, or any other characteristic protected by federal, state or local laws.

By applying to our jobs you agree to receive calls, AI-generated calls, text messages, or emails from Pyramid Consulting, Inc. and its affiliates, and contracted partners. Frequency varies for text messages. Message and data rates may apply. Carriers are not liable for delayed or undelivered messages. You can reply STOP to cancel and HELP for help. You can access our privacy policy here.

We want you to help us shape the future of shopping experiences and deliver on our purpose of connecting people with the products and experiences that enrich their lives. Joining SAS Retail Services, an Advantage Solutions company, means joining a network of 65,000 teammates serving 4,000+ brands and retail customers across 40+ countries. All the while, being provided the opportunities, support, and enrichment you need to grow your career.

In this role, you will provide in-store merchandising support to Retailers to meet shoppers' needs. This includes building displays and end caps, resetting shelves with product rotation, and tracking inventory to ensure that stores and suppliers maximize sales opportunities. Are you ready to shape the future of shopping and get it done with us?

What we offer:

• Competitive wages; $ 16.00 per hour
• Growth opportunities abound - We promote from within
• No prior experience is required as we provide training and team support to help you succeed
• Additional hours may be available upon request
• We offer benefits that can be customized to meet your family's needs, including medical, dental, vision, life insurance, supplemental voluntary plans, wellness programs, and access to discounts through Associate Perks

Now, about you:

• Are comfortable interacting with customers and management in a friendly, enthusiastic, and outgoing manner
• You're 18 years or older
• Can perform physical work of moving, bending, standing and can lift up to 50 lbs.
• Have reliable transportation to and from work location
• Demonstrate excellent customer service and interpersonal skills with our clients, customers and team members
• Are a motivated self-starter with a strong bias for action and results
• Work independently, but also possess successful team building skills
• Have the ability to perform job duties with a safety-first mentality in a retail environment

If this sounds like you, we can't wait to learn more about you. Apply Now!

We want you to help us shape the future of shopping experiences and deliver on our purpose of connecting people with the products and experiences that enrich their lives. Joining SAS Retail Services, an Advantage Solutions company, means joining a network of 65,000 teammates serving 4,000+ brands and retail customers across 40+ countries. All the while, being provided the opportunities, support, and enrichment you need to grow your career.

In this role, you will provide in-store merchandising support to Retailers to meet shoppers' needs. This includes building displays and end caps, resetting shelves with product rotation, and tracking inventory to ensure that stores and suppliers maximize sales opportunities. This is a traveling position that requires regular travel as a primary requirement of the role. Travel roles may require various degrees of travel up to 50% or more of the time. Are you ready to shape the future of shopping and get it done with us?

What we offer:

• Competitive wages; $ 18.00 per hour
• Growth opportunities abound - We promote from within
• Paid travel with overnight stays
• No prior experience is required as we provide training and team support to help you succeed
• Additional hours may be available upon request
• We offer benefits that can be customized to meet your family's needs, including medical, dental, vision, life insurance, supplemental voluntary plans, wellness programs, and access to discounts through Associate Perks

Now, about you:

• Are comfortable interacting with customers and management in a friendly, enthusiastic, and outgoing manner
• You're 18 years or older
• Can perform physical work of moving, bending, standing and can lift up to 50 lbs.
• Have reliable transportation to and from work location
• Demonstrate excellent customer service and interpersonal skills with our clients, customers and team members
• Interested in traveling within and outside of your home state, with overnight hotel stays
• Are a motivated self-starter with a strong bias for action and results
• Work independently, but also possess successful team building skills
• Have the ability to perform job duties with a safety-first mentality in a retail environment

If this sounds like you, we can't wait to learn more about you. Apply Now!

A MISSION WORTHY OF A CAREER! If you're looking for "just a job," then stop reading right now.

But, if you're looking for a long-term federal law enforcement career, one that makes a difference every day to our country and its citizens, then the U.S.

Border Patrol (USBP) would like you to take the first step to becoming an entry level Border Patrol Agent.

USBP is hiring immediately to fill full-time, entry-level, career positions in federal law enforcement where your prior experience in public safety, security, military police or law enforcement may qualify.

Train and work with an elite team of professionals whose camaraderie, pride, and sense of purpose are hallmarks of their daily mission of protecting America.

Now is the time to make your move because, along with excellent base pay, exceptional benefits, and job stability, USBP is offering up to $60,000 in additional incentives (see details below) .

Salary and Benefits Annual base salary for newly appointed BPAs varies per grade, as follows: GL-5/GL-7 $51,632
- $92,219 per year.

Border Patrol Agents are eligible to select from an array of federal employment benefits that include health, dental and other insurance plans, a generous annual and sick leave program, and participation in the Thrift Savings Plan, a retirement plan akin to a traditional ROTH 401(k) offering.
*Recruitment Incentive
* Newly appointed Border Patrol Agents (as defined in 5 CFR 575.102 ) will be eligible for up to $20,000 in incentives.

The first $10,000 will be paid upon successful completion of the Border Patrol Academy, with the remaining $10,000 awarded for accepting a prioritized location such as Sierra Blanca, Presidio, Sanderson, Comstock, Freer or Hebbronville, TX; Lordsburg, NM; or Ajo, AZ.
*Retention Incentive
* Newly appointed Border Patrol Agents may also qualify for up to $40,000 in additional incentives distributed over their first four years.

Duty Locations IMPORTANT NOTICE: Duty assignments available at the time of offer may include the Southwest Border, including prioritized locations.

U.S.

Border Patrol determines duty assignments at the time of offer based on operational needs, which may or may not align with candidates' first-choice preferences.

Relocation may be required.

Duty location impacts pay rates; locality pay for federal law enforcement is higher in some locations than others.

A fully trained BPA may be eligible for up to an additional 25% of base pay per the BPA Pay Reform Act of 2014.

This is a career ladder position with a grade level progression of GL-5, GL-7, GL-9, GS-11, and GS-12.

You will be eligible for a promotion to the next higher grade level (without reapplying) once you successfully complete 52 weeks in each grade level.

Duty Locations: You will be asked to select your preferred location for one of the following mission critical locations: Big Bend Sector Stations
-
*Presidio, Van Horn,
*Sanderson, Alpine,
*Sierra Blanca, Marfa Buffalo Sector Stations
- Wellesley Island Del Rio Sector Stations
- Del Rio, Brackettville,
*Comstock, Eagle Pass North, Eagle Pass South, Carrizo Springs, Uvalde El Paso Sector Stations
- Alamogordo, Clint, Deming, El Paso, Fort Hancock, Las Cruces,
*Lordsburg, Santa Teresa, Ysleta El Centro Sector Stations
- El Centro, Indio, Calexico Grand Forks Sector Stations
- Pembina Havre Sector Stations
- Havre, Malta, Plentywood, Scobey, Sweetgrass Houlton Sector Stations
- Calais, Fort Fairfield, Jackman, Rangeley, Van Buren Laredo Sector Stations
- Laredo South, Cotulla,
*Hebbronville, Laredo West,
*Freer, Laredo North, Zapata Rio Grande Valley Sector Stations
- Rio Grande City, Fort Brown, McAllen, Brownsville, Falfurrias, Weslaco, Kingsville, Harlingen San Diego Sector Stations
- Boulevard, Brownfield, Campo, Chula Vista, Imperial Beach, Murrieta, San Clemente Spokane Sector Stations
- Colville, Curlew, Metaline Falls, Oroville Swanton Sector Stations
- Beecher Falls, Burke, Champlain, Newport, Richford Tucson Sector Stations
-
*Ajo, Tucson, Nogales, Douglas, Brian A Terry, Sonoita, Casa Grande, Three Points Substation, Willcox Yuma Sector Stations
- Blythe, Yuma, Wellton Duties and Responsibilities As a BPA, you will be part of our 60,000 workforce that strives to protect the American people by safeguarding our borders, deterring illicit activity, and enhancing the nation's economic prosperity.

Being a BPA makes you a valuable member of the Federal Law Enforcement Officer (LEO) profession.

Typical assignments include: Detecting and questioning people suspected of violating immigration and custom laws and inspecting documents and possessions to determine citizenship or violations Preventing and apprehending undocumented noncitizens and smugglers of noncitizens at or near the borders by maintaining surveillance from covert positions to include using infrared scopes during night operations Interpreting and following tracks, marks, and other physical evidence of illegal entry of persons or contraband Performing farm checks, building checks, traffic checks, city patrols, and transportation checks Patrolling the international boundary and coastal waterways using a variety of government assets such as vehicles, horses, vessels, watercraft, off-road vehicles, ATVs, snowmobiles, and motorcycles for the accomplishment of the USBP Mission.

Qualifications You qualify for the GL-5 grade level if you possess one of the following: Experience: One (1) year of general work experience that demonstrates the ability to take charge, make sound decisions, and maintain composure in stressful situations; to learn regulations, methods, and techniques through classroom training and/or on-the-job instruction; and the ability to gather concise information through questioning, observation, and examination of documents and records; OR Education Substitution: A bachelor's degree or successful completion of a full four-year course of study in any field leading to a bachelor's degree from an accredited college or university; OR Combination of Experience and Education: A combination of general work experience AND successfully completed college education.

This will be calculated using your resume and official or unofficial transcripts submitted with your application.

You qualify for the GL-7 grade level if you possess one of the following: Experience: One year of specialized work experience that shows you have the skills necessary to: Make sound judgments and decisions in the use of firearms.

Deal effectively with people in a courteous and tactful manner in connection with law enforcement matters.

Analyze information rapidly and make prompt decisions where you will be expected to make arrests after the completion of required training and apply these skills in a law enforcement capacity such as criminal code enforcement, determining violations of laws, correctional or rehabilitation work involving criminal offenders, security, military, etc.

The above experience will be applied in connection with the following: Make arrests and exercise sound judgment in the use of firearms; deal effectively with people in a courteous manner in connection with law enforcement matters; analyze information rapidly and make prompt decisions; or develop and maintain contact with a network of informants.

Education Substitution for the GL-7 grade level: A bachelor's degree with superior academic achievement, which is based on (1) class standing, (2) grade-point average (i.e., GPA of 3.0 or higher out of a possible 4.0), or (3) honor society membership.

Or will receive a bachelor's degree with Superior Academic Achievement.

Or one full year of graduate-level education in a field of study related to law enforcement (e.g., criminal justice, homeland security, justice studies, law enforcement, courts and judicial systems, forensic technology, forensic psychology, or corrections and rehabilitation) from an accredited college or university; OR A Combination of Experience and Education: This will be calculated using your resume and official or unofficial transcripts submitted with your application.

Note: If you have previous or current law enforcement or military law enforcement experience, you may qualify at the GL-9 and or GS-11 grade level.

Please refer to the BPA GL-9
- 11 announcement.

Other Requirements Citizenship : You must be a U.S.

Citizen to apply for this position.

Residency : You must have had primary U.S.

residency (includes protectorates as declared under international law) for at least three of the last five years.

Age Restriction : In accordance with Public Law 100-238, this position is covered under law enforcement retirement provisions.

Candidates must be referred for selection to the Border Patrol Agent position before reaching their 40th birthday in accordance with Department of Homeland Security Directive 251-03.

The age restriction may not apply if you are currently serving or have previously served in a federal civilian law enforcement (non-military) position covered by Title 5 U.S.C.

8336(c) or Title 5 U.S.C.

8412(d).

Veterans' Preference : You may also be eligible for an excepted service Veterans Recruitment Appointment (VRA).

The age restriction does not apply if you are Veterans' Preference eligible.

Formal Training : After you are hired, you will be detailed to the U.S.

Border Patrol Academy in Artesia, New Mexico, for approximately six (6) months of intensive instruction in immigration and nationality laws, law enforcement and USBP-specific operations, driver training, physical techniques, firearms, and other courses.

Border Patrol work requires the ability to speak and read Spanish, as well as English.

Border Patrol Agents will be provided training to become proficient with the Spanish language at the Academy.

How to Apply: Click the Apply button on this site.

You will be linked to the CBP Talent Network registration page.

For Position of Interest, select Border Patrol Agent, then complete the pre-screening questions.

You'll then receive a link(s) to the BPA Job Opening Announcements (JOAs) on USAJOBS, the federal government's official employment site, to complete your application.

Be certain to review ALL details of the job opportunity announcement and follow all instructions in the application process, including items (resume, transcripts, etc.) to submit.

You will be evaluated based on your resume, supporting documents, and the BPA Entrance Exam .

If you have questions about the application process, contact a recruiter through the U.S.

Border Patrol page: /s/usbp .

As a subscriber to the CBP Talent Network, you'll receive monthly emails with information about webinars, career expos, and future opportunities with CBP.

At TJX Companies, every day brings new opportunities for growth, exploration, and achievement. You’ll be part of our vibrant team that embraces diversity, fosters collaboration, and prioritizes your development. Whether you’re working in our four global Home Offices, Distribution Centers or Retail Stores—TJ Maxx, Marshalls, Homegoods, Homesense, Sierra, Winners, and TK Maxx, you’ll find abundant opportunities to learn, thrive, and make an impact. Come join our TJX family—a Fortune 100 company and the world’s leading off-price retailer.

Job Description:

Reporting into the Senior Vice President, Corporate Human Resources, the Assistant Vice President, HR Business Partner will provide thought leadership, strategic counsel, advisory and consultative services to business leaders across the corporate organizations, both domestically and internationally, as appropriate.

Responsibilities:

• Contributes to the business strategy by helping business leaders to identify, prioritize, and build organizational capabilities, behaviors, structures and processes
• Focused on identifying and implementing strategic talent solutions in support of evolving corporate organizations; ensuring the overall organization and culture are designed around strategic talent pipeline with a heavy focus on talent development, succession planning, and a culture of inclusion
• Model and build leadership capability at the team and individual level, inclusive of providing high level coaching and counsel to those leaders
• Reviews and benchmarks the internal and external environment to improve the HR practices and identify new opportunities where HR can add value to the business
• The AVP HRBP will collaborate with peers and team and leverage HR’s Centers of Expertise (COE’s) and the HR Operations Support Center for business solutions, guiding the acquisition, staffing, development, and retention of TJX Associates
• Manages and directs the work of more than three full-time Associates. Interviews and recommends the hiring of associates. Evaluates associate performance, recognizing Associates through reward and discipline. Recommends career development and termination of associates. Oversees ongoing functional training of Associates.

Requirements:

• Minimum of 10 to 15 years of related HR business and management experience with experience developing and implementing strategic talent initiatives
• Bachelor’s Degree or equivalent job experience
• Track record of solving complex organizational talent related challenges
• Experience with change management and leading organizational change
• Demonstrated agility in learning and adapting strategies to market realities
• Facilitates effective workforce planning to identify the capacity and capability of the organization to deliver its short and long-term objectives
• Accountable for assessing and developing talent across the department including building a diversified talent pool to fill key current and future positions and ensuring development plans that support Associate growth and development
• Mentors the team on relationship management and business sense and influences and generates innovative business ideas
• Act as a collaborative partner with leaders and positively influences management
• Strong demonstrated leadership presence
• Ability to use HR reporting and analytics to generate insights and present findings back to the business
• Demonstrated understanding of project management principles with experience in leading and/ or partnering on large-scale organization change efforts
• Basic knowledge and use of Microsoft; Word, Excel, PowerPoint, Teams
• Progressive knowledge of Human Resources
• Collaboration & Influencing skills
• Strategic prioritization & planning skills
• Ability to build and develop highly effective teams
• Ability to analyze and interpret financial reports
• Coaching, mentoring, providing counsel and guidance

Benefits include Associate discount; 401(k) match; medical/dental/vision; HSA; health care FSA; life insurance; short/long-term disability; paid holidays/vacation /sick/bereavement/parental leave; EAP; incentive programs for management; auto/home insurance discounts; tuition reimbursement; scholarship program; adoption/surrogacy assistance; smoking cessation; child care/cell phone discounts; pet/legal insurance; credit union; referral bonuses. All benefits are subject to applicable plan or program terms (including eligibility terms) and may change from time to time. Contact your TJX representative for more information.

In addition to our open door policy and supportive work environment, we also strive to provide a competitive salary and benefits package. TJX considers all applicants for employment without regard to race, color, religion, gender, sexual orientation, national origin, age, disability, gender identity and expression, marital or military status, or based on any individual's status in any group or class protected by applicable federal, state, or local law. TJX also provides reasonable accommodations to qualified individuals with disabilities in accordance with the Americans with Disabilities Act and applicable state and local law.

Company Description

Jammin With You is a dynamic and rapidly growing children's music education organization. We provide high-energy classes, private instrument lessons, school enrichment, and performance programs. Our mission is to combine expert music pedagogy with a fun and engaging approach, helping children build skills, confidence, and a lifelong love of music. We are passionate about fostering creativity and growth through music education.

Role Description

We are seeking a part-time Private Music Teacher. As a JWY teacher, you will be responsible for conducting one-on-one music lessons in students' homes, focusing on piano/voice/guitar/drum instruction and music theory. Your role will also include preparing students for performances, fostering their enthusiasm for music, adapting teaching methods to meet individual needs, and communicating progress with families and guardians.

Qualifications

• Strong proficiency in Music Theory and Music Education
• Skilled in Music Performance and instruction
• Passion for teaching and inspiring a love of music in children
• Strong communication skills to engage with students and their families
• Organizational skills and adaptability to tailor lessons to students' unique needs
• Bachelor's degree in Music, Music Education, or a related field
• Experience teaching music to children is highly desirable

Tax Manager

Want to make an impact?

The Tax Manager reports directly to the Assistant Vice President of Employment & Environmental Tax and manages 2 Analysts. The team supports TJX's global mobility finance and employment tax processes, ensuring compliance with local and international tax regulations while supporting associates on assignment. Acting as a key liaison across Tax, Payroll, Treasury, Finance Shared Services, HR, and Legal, the position provides technical expertise and guidance on global mobility, expatriate taxation, employment tax matters and reward & benefit programs.

What You'll Do:

Global Mobility:

• Ensure timely and accurate information for expatriate and localized associates’ tax returns.
• Oversee compensation reporting and local payroll tax withholdings.
• Manage corporate and individual obligations under the Global Mobility Program.
• Liaise with third-party providers to ensure accurate reporting and compliance.
• Review and approve tax equalization calculations and related payments/credits.
• Act as primary contact with tax authorities for expatriate-related issues.
• Develop annual expatriate budgets and update as needed.
• Provide robust and accurate accounting advice and solutions for all non-routine transactions to the local country legal entities
• Support payroll related expat GL accounts and balance sheet reconciliations.
• Prepare tax equalization accrual reconciliations.
• Act as finance SME for domestic relocation policies.

Employment Tax:

• Partner with and provide support to Legal and HR on reward and benefit programs.
• Advise on tax aspects of new associate benefits, programs, and policies, including Benefits in Kind.
• Collaborate with Finance and business partners on expense policy design and compliance.
• Support local accounting and payroll teams in accurate employment tax reporting.

What You'll Need:

• 5+ years of relevant income tax or global mobility tax experience in international environment
• Bachelor’s Degree in Accounting or related equivalent preferred
• CPA or Master’s in Taxation or Accounting preferred
• Strong interpersonal and managerial skills to lead professional staff
• Strong technical knowledge of global mobility and employment tax
• Excellent communication and influencing skills
• Deep understanding of internal and regional tax regulations and reporting requirements
• Ability to manage complex, cross-border processes
• Proactive, detail-oriented, and solution-focused
• Experience with influencing cross-functionally and globally to deliver excellent results
• Capable of working with the teams and associates across multiple geographies including, Europe and Australia

Benefits include Associate discount; 401(k) match; medical/dental/vision; HSA; health care FSA; life insurance; short/long-term disability; paid holidays/vacation /sick/bereavement/parental leave; EAP; incentive programs for management; auto/home insurance discounts; tuition reimbursement; scholarship program; adoption/surrogacy assistance; smoking cessation; child care/cell phone discounts; pet/legal insurance; credit union; referral bonuses. All benefits are subject to applicable plan or program terms (including eligibility terms) and may change from time to time. Contact your TJX representative for more information.

In addition to our open door policy and supportive work environment, we also strive to provide a competitive salary and benefits package. TJX considers all applicants for employment without regard to race, color, religion, gender, sexual orientation, national origin, age, disability, gender identity and expression, marital or military status, or based on any individual's status in any group or class protected by applicable federal, state, or local law. TJX also provides reasonable accommodations to qualified individuals with disabilities in accordance with the Americans with Disabilities Act and applicable state and local law.

Location:

USA Home Office Framingham MA 550 Cochituate Rd

This position has a starting salary range of $103,900.00 to $134,900.00 per year. Actual starting pay is determined by a number of factors, including relevant skills, qualifications, and experience. This position is eligible for an annual incentive as well as long-term incentives.

Position Summary:

The Associate Director, Quality Control will be responsible for providing strategic, scientific, and operational leadership for the development, qualification, validation, and lifecycle management of analytical methods supporting Upstream Bio’s lead program verekitug. This role will manage and execute GMP quality control (QC) activities directly related to batch release for clinical trial material supply. The leader in this role must assure that quality controls for investigational new drugs (investigational medicinal products) meet all quality requirements, regulatory standards, and meet continuous clinical supply and delivery expectations. The Associate Director will report to Senior Director of Analytical and serve as a key partner to Quality, CMC, Regulatory, and cross-functional teams. This individual will provide technical guidance and business acumen to ensure execution of analytical activities for late-stage programs through BLA/MAA submission, approval, and commercial launch.

Key Responsibilities:

• Author, review and approve analytical method procedures/SOPs
• Author, review and approve analytical method transfer/qualification/validation protocols and reports
• Manage external CDMOs and CROs to execute Development and GMP release and stability testing of Drug Substance and Drug Product in a compliant-manner
• Establish and manage reference standard and critical reagent programs
• Participate in the laboratory quality system activities such as internal audits, writing standard operating procedures, and documentation review.
• Perform data verification and audits in order to ensure accuracy of data and analytical processes.
• Ensure compliance with company policies and SOPs as well as global health authority guidelines.
• Create, analyze, verify, and approve QC data such as method validation, release and stability, results, reports, and Certificates of Analysis (COAs).
• Generate, review, and revise specifications, SOPs, and other QC laboratory and testing documentation.
• Lead Out-of-Specification (OOS), Out-of-Trend (OOT), and Deviation investigations related to the QC laboratory and ensure effective corrective and preventive actions (CAPAs) are implemented.

Qualifications:

• Experience in stability study performance/evaluation and/or knowledge/familiarity with USP/compendial testing is helpful.
• Excellent verbal and written communication/interpersonal skills, problem-solving skills, organizational skills, and the ability to work in a diverse team environment are essential.
• Proficiency with Microsoft software (Word / EXCEL / PowerPoint), Stability software and statistical analysis/trending to support shelf life and labeling is expected.

Knowledge and skills (general and technical) preferred:

• Broad background, strong comprehension, and demonstrated skills in analytical methods development/validation/transfer/similar, reference standards characterization/structural elucidation, and unknown identification.

Education level and/or relevant experience required:

• Bachelor’s degree in a scientific or allied health field (or equivalent degree) and 10+ years of demonstrated success in leading cross-functional teams and managing projects along with 7+ years relevant analytical experience in a cGMP-compliant pharmaceutical laboratory environment. Any ASQ or other certifications is a plus.

About Upstream Bio:

Upstream Bio is a public company based in Waltham, MA. We are developing verekitug, the only known antagonist currently in development that targets the receptor for Thymic Stromal Lymphopoietin (TSLP). We have advanced this highly potent monoclonal antibody into separate Phase 2 trials for the treatment of severe asthma and chronic rhinosinusitis with nasal polyps (CRSwNP) and plan to initiate development in chronic obstructive pulmonary disease (COPD). Our experienced team is committed to maximizing verekitug’s unique attributes to address the substantial unmet needs for patients underserved by today’s standard of care. Learn more about us at .

Compensation

Target Salary Range: $176,400 - $215,600

*Base Compensation for this role will depend on a number of factors including a candidate’s qualifications, skills, competencies, and experience. Base pay is only one component of the company’s total rewards package. All regular employees are also eligible for the corporate bonus program or the incentive compensation program (if applicable), as well as equity. Additional benefits include health care, vision, dental, retirement, PTO, etc.

Medical Device Manufacturing Engineer Co-Op/Intern

On-site in Seaport, Massachusetts May-August (extension possible)

Amplitude Vascular Systems (AVS), an early-stage medical device company focused on safely and effectively treating severely calcified arterial disease, is seeking a Manufacturing Engineer-Co-Op to support our Operations team. This individual will work in a cross-functional role (Quality/Manufacturing/R&D) supporting the manufacturing of devices and associated instruments and technologies.

Key Responsibilities:

• Willing to work for cross functional teams (Operations, R&D and Quality & Regulatory.)
• Creating and modifying designs/drawings utilizing SolidWorks
• Testing prototype devices for functionality
• Supporting manufacturing with failure analysis
• Working in the lab, summarizing data, performing tests, and writing technical reports
• Participating and collaborating in team meetings and updates.
• Experience in Microsoft Word, Excel, and PowerPoint is essential
• Ability to work independently as well as take direction and complete tasks with or without help or supervision.

.Qualifications:

• In pursuit of Bachelor's degree in Mechanical, Industrial, Manufacturing, Electrical, or Biomedical Engineering. In Junior year or above.
• Self-motivated with an interest in medical devices
• 3-D modeling skills (NX Unigraphics & Solidworks Preferred)
• Experience using hand tools and performing mechanical testing
• Proven problem-solving capabilities
• Ability to communicate technical information
• Previous co-op completed in manufacturing at a medical device demonstrating skillsets listed above preferred.
• A minimum G.P.A. of 3.0
• Available to work full-time (40 hrs/week) May-August 2026
• This is an onsite position located in Waltham, MA.

AVS is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, age, national origin, or protected veteran status and will not be discriminated against on the basis of disability.