Upstream Bio Inc Jobs in Usa

Community hospital part of system looking to bring on Director Bio-Medical! Sign On Bonus! Full Relocation!

Provides leadership and is responsible for the implementation of the program and services. Participates in defining strategic direction of the Bio-Med program through short and long-term goal setting, technology assessment and planning, medical device integration, operations, risk analysis, security, vendor and contract management, fiduciary responsibilities, and required reporting. Assists leadership with developing and strengthening facility and vendor relationships. Ensures that facility program meets and exceeds regulatory requirements for healthcare technology management. Develops and executes KPI’s.

Education:

• Minimum of Tech School certification or Associate's Degree. Bachelor’s degree in preferred.

Experience:

• 5+ years of previous related experience.

Technical Skills

• Experience with healthcare technology management programs including leadership Medical equipment knowledge (manufacturers, models, modalities, capital planning, etc…)
• Understanding of regulatory requirements for medical devices (CMS, TJC, CLIA, AABB, NRC,State, Local)

The Department of Biomedical Sciences invites applications for the Dr. Richard J. Bellucci Postdoctoral Fellowship. This Fellowship is one of the most prestigious offered by Creighton University and is reserved for highly promising early-career scientists who are engaged in hearing research. A successful candidate will be expected to conduct leading research in hearing science, mentor junior trainees, and develop a strong publication and presentation record.

We offer:

• Exceptional faculty and mentorship
• Numerous internal funding opportunities
• A strong University benefits package

Qualifications:

• Terminal degree (PhD and/or MD) with extensive, demonstrated experience in any of the following fields: Neuroscience, Chemistry, Developmental Biology, Bioinformatics or other related fields
• A commitment to hearing research
• Excellent communication skills, oral and written
• Strong publication and conference record
• Enthusiasm to work in a highly diverse, collaborative environment

Applicants must provide:

1. A ONE-page essay demonstrating their commitment to hearing research and a project that merits this Fellowship. This essay should include:
   1. A preliminary research plan, hypothesis, or major question.
   2. A member of Center faculty whose lab is appropriate for their research interest.
      1. Applicants are strongly encouraged to contact their proposed mentor in advance of applying to discuss their proposal. Current Center Faculty: Drs. Peter Steyger, David He, Marisa Zallocchi, Litao Tao, Justine Renauld, Jemma Webber, Allison Coffin, Kelsey Anbul, and Hui Hong

2. A biosketch (e.g., NIH Biosketch) that includes tangible products that support your appointment. These may include but are not limited to: Publications, Grant applications submitted and grants received, Patents, Podium and poster presentations, Professional development and career preparation, Volunteer experience

3. Names and contact emails of three professional referees who can provide a confidential letter of recommendation that speaks to their ability to conduct exceptional postdoctoral hearing research at a leading auditory-vestibular neuroscience institution. At least one referee should be outside the applicant's current institution.

Incomplete applications will not be considered.

The Dr. Richard J. Bellucci Translational Hearing Center is based on a highly collaborative and multi-disciplinary research model. We therefore welcome applicants who bring a broad range of applicable skills and perspectives to the Center as they fuel our innovation.

Under general supervision, provides a wide variety of moderately complex laboratory testing and technical lab support for a research facility. Requires knowledge of the processes/procedures in testing, documenting experiments, maintaining laboratory notebook, analyzing data, and reporting using complex statistical computer software.

Qualifications:

Bachelor's degree in related field of Science required;
2-4 year's research lab experience

Knowledge, Skills, Abilities:

Understanding of research methods, laboratory techniques, and care of laboratory equipment;

Ability to interpret data, troubleshoot and resolve technical issues;

Proficiency in Microsoft Office Suite to include Word, Excel; PowerPoint and Outlook;

Detail oriented;

Analytical skills;

Strong work ethic, excellent written and communication skills, and the ability to work independently;

Ability to work evenings, weekends, and holidays depending upon research needs

Physical Requirements:

Seeing: 75 - 100%

Hearing: 50 - 74%

Standing/Climbing/Mobility: 50 - 74%

Lifting/Pulling/Pushing: 25 - 49 % (pound: 15 lbs.)

Fingering/Grasping/Feeling: 75-100%

Travel: No

Exposure to Blood Borne pathogens: No and Yes

AAP/EEO Statement:

Creighton University is committed to providing a safe and non-discriminatory educational and employment environment. The University admits qualified students, hires qualified employees and accepts patients for treatment without regard to race, color, religion, sex, marital status, national origin, age, disability, citizenship, sexual orientation, gender identity, gender expression, veteran status, or other status protected by law. Its education and employment policies, scholarship and loan programs, and other programs and activities, are administered without unlawful discrimination.

Disclosure Statement:

This description describes the general nature of work to be performed and does not include an exhaustive list of all duties, skills, or abilities required. Regular, reliable attendance is an essential function and all employees are required to follow any other job-related instructions and to perform any other job-related duties as requested by their supervisor. Employees may also be required to work in excess of normal working hours as workloads and seasonal activities necessitate. A complete description is available in the Human Resource office located at 3006 Webster Street Omaha, NE. Creighton University reserves the right to modify duties, responsibilities and activities at any time with or without notice.

WE ARE PDHGROUP

We are a values-driven company that strives to provide the best quality service and products for the construction industry. As a provider and installer of Division 8, Division 10, Division 27, and Division 28 products, our business is built on honesty, integrity, and the ability to get the job completed on-time and with complete customer satisfaction. Our team brings over 425 years of combined experience and includes some of the most knowledgeable people in the industry.

JOB SUMMARY:

As a Project Manager, you will be accountable for the overall direction, coordination, implementation, execution, control and completion of any given project. Additionally, the Project Manager ensures budget and deadlines are met and consistent with project standards.

DUTIES AND ESSENTIAL JOB FUNCTIONS:

• Create a Schedule of Values for our pay applications and submit to the General Contractor.
• Analyze the construction schedule and create a schedule for submittals, material ordering and estimated field labor durations & project completion.
• Create submittals for doors, frames and hardware from architectural plans and specification.
• Manage and respond to electronic contractual changes (RFI’s, PC’s, Etc.). Quote changes that affect our material and/or labor cost. Distribute Change Order Due letters to the contractor.
• Order materials (Purchase orders) from approved submittals for timely delivery according to the construction schedule or as agreed upon with the contractor for billed and stored material.
• Support the Performance Door project field supervisor for the timely delivery of materials according to the construction schedule. Send field use drawings periodically reflecting updated schedules incorporating project revisions.
• Provide monthly pay application to the accounting department including back up documentation for stored or FSC materials.
• Actively pursue contractual “Change Orders” from “price and proceed” CO Due letters. Take an active role in collecting money.
• Approve weekly vendor invoices for payment. Check vendor costs against our purchase order.
• Other job duties and responsibilities as needed.

Position Summary:

The Associate Director, Quality Control will be responsible for providing strategic, scientific, and operational leadership for the development, qualification, validation, and lifecycle management of analytical methods supporting Upstream Bio’s lead program verekitug. This role will manage and execute GMP quality control (QC) activities directly related to batch release for clinical trial material supply. The leader in this role must assure that quality controls for investigational new drugs (investigational medicinal products) meet all quality requirements, regulatory standards, and meet continuous clinical supply and delivery expectations. The Associate Director will report to Senior Director of Analytical and serve as a key partner to Quality, CMC, Regulatory, and cross-functional teams. This individual will provide technical guidance and business acumen to ensure execution of analytical activities for late-stage programs through BLA/MAA submission, approval, and commercial launch.

Key Responsibilities:

• Author, review and approve analytical method procedures/SOPs
• Author, review and approve analytical method transfer/qualification/validation protocols and reports
• Manage external CDMOs and CROs to execute Development and GMP release and stability testing of Drug Substance and Drug Product in a compliant-manner
• Establish and manage reference standard and critical reagent programs
• Participate in the laboratory quality system activities such as internal audits, writing standard operating procedures, and documentation review.
• Perform data verification and audits in order to ensure accuracy of data and analytical processes.
• Ensure compliance with company policies and SOPs as well as global health authority guidelines.
• Create, analyze, verify, and approve QC data such as method validation, release and stability, results, reports, and Certificates of Analysis (COAs).
• Generate, review, and revise specifications, SOPs, and other QC laboratory and testing documentation.
• Lead Out-of-Specification (OOS), Out-of-Trend (OOT), and Deviation investigations related to the QC laboratory and ensure effective corrective and preventive actions (CAPAs) are implemented.

Qualifications:

• Experience in stability study performance/evaluation and/or knowledge/familiarity with USP/compendial testing is helpful.
• Excellent verbal and written communication/interpersonal skills, problem-solving skills, organizational skills, and the ability to work in a diverse team environment are essential.
• Proficiency with Microsoft software (Word / EXCEL / PowerPoint), Stability software and statistical analysis/trending to support shelf life and labeling is expected.

Knowledge and skills (general and technical) preferred:

• Broad background, strong comprehension, and demonstrated skills in analytical methods development/validation/transfer/similar, reference standards characterization/structural elucidation, and unknown identification.

Education level and/or relevant experience required:

• Bachelor’s degree in a scientific or allied health field (or equivalent degree) and 10+ years of demonstrated success in leading cross-functional teams and managing projects along with 7+ years relevant analytical experience in a cGMP-compliant pharmaceutical laboratory environment. Any ASQ or other certifications is a plus.

About Upstream Bio:

Upstream Bio is a public company based in Waltham, MA. We are developing verekitug, the only known antagonist currently in development that targets the receptor for Thymic Stromal Lymphopoietin (TSLP). We have advanced this highly potent monoclonal antibody into separate Phase 2 trials for the treatment of severe asthma and chronic rhinosinusitis with nasal polyps (CRSwNP) and plan to initiate development in chronic obstructive pulmonary disease (COPD). Our experienced team is committed to maximizing verekitug’s unique attributes to address the substantial unmet needs for patients underserved by today’s standard of care. Learn more about us at .

Compensation

Target Salary Range: $176,400 - $215,600

*Base Compensation for this role will depend on a number of factors including a candidate’s qualifications, skills, competencies, and experience. Base pay is only one component of the company’s total rewards package. All regular employees are also eligible for the corporate bonus program or the incentive compensation program (if applicable), as well as equity. Additional benefits include health care, vision, dental, retirement, PTO, etc.

This is a six month assignment in Vacaville

This potsition is for local candidates as there is no travel and living expenses

This is a W2 Position.

Process Engineer I

Summary:

This position is located at Lonza’s production facility in Vacaville, California. The production facility makes pharmaceutical proteins from mammalian cells using large-scale production techniques. This temporary contract position provides hands-on technical support for Process Analytical Technology (PAT) systems deployed on the manufacturing floor at a large-scale biopharmaceutical facility. PAT systems play a critical role in monitoring mammalian cell culture processes by measuring key parameters such as cell density, viability, and metabolite concentrations. Maintaining these systems in a reliable, ready-to-use state is essential for ensuring consistent manufacturing performance.

In this role, you will support day-to-day operation, maintenance, and troubleshooting and repair of PAT instruments used in GMP manufacturing. You will work closely with the Frontline Upstream (FLUS) System Owner, Manufacturing, and Instrumentation staff to assess system issues, perform equipment health checks, execute planned improvements, and assist with investigations into unplanned events. This position supports the increased workload associated with the deployment of several new PAT systems in parallel with existing instruments. This position offers the opportunity to gain hands-on experience with advanced PAT used to support mammalian cell culture and purification operations. The FLUS and Instrumentation groups provide technical support for a wide range of analytical instruments used to monitor cell growth, metabolite profiles, and process performance throughout the manufacturing lifecycle.

Job Duties:

Responsibilities/activities may include, but not limited to:

• Performing routine maintenance, calibration checks, and system readiness activities for PAT instruments such as cell counters and metabolic analyzers (e.g., Cedex Bio, Cedex HiRes, Cedex Cobas).

• Supporting manufacturing operations by responding to system-related issues, troubleshooting instrument performance, and documenting observed problems.

• Assisting in the investigation of unplanned equipment events using structured problem-solving tools and contributing to root cause assessments.

• Conducting equipment health monitoring and contributing to reliability improvement activities to increase system uptime.

• Executing planned equipment changes, minor upgrades, and configuration updates under the direction of the PAT System Owner.

• Reviewing and interpreting instrument data to identify basic trends or abnormalities.

• Supporting adherence to data integrity principles and helping maintain data consistency within systems such as Smartline Data Cockpit.

• Collaborating with Manufacturing, FLUS, Automation, QA, and vendors to ensure systems are functioning as intended.

• Assisting with documentation updates, tracking of work activities, and preparing technical summaries as needed.

• Working independently to accomplish assigned tasks while keeping stakeholders informed of progress.

Education and Experience:

• B.S., M.S., or Ph.D in an engineering or analytical/scientific discipline.

• Prior hands-on experience with analytical systems is required.

• Experience using cell counters and metabolite analyzers (Cedex Bio, Cedex HiRes, Cedex Cobas) in GMP Manufacturing or QC Labs preferred.

Knowledge/Skills/Competencies:

• Working knowledge of current Good Manufacturing Practices (cGMPs) as applied to biopharmaceutical manufacturing or similar regulated industries.

• General understanding of biotech analytical methods and laboratory practices.

• Experience troubleshooting analytical instruments and interpreting equipment performance data.

• Flexibility in problem solving and work hours to meet business objectives.

• Familiarity with data management systems; experience with Smartline Data Cockpit is highly desirable.

• Strong interpersonal and communication skills; able to work effectively with operators, engineers, scientists, and external vendors.

• Ability to work independently and manage assigned tasks with limited supervision.

• Demonstrated ability to evaluate technical situations, propose solutions, and execute corrective actions.

• Strong verbal and written communication skills, including documentation, reporting, and stakeholder updates.

• Ability to build productive working relationships with end users and equipment vendors.

• Strategic thinking mindset with the ability to convert system needs into actionable activities.

• Builds productive relationships with partners; focuses on customer needs.

Class of 2026 welcome to apply!

Backed by global venture capital investors, Harba Solutions is a high-growth consultancy specializing in talent solutions for the Life Sciences industry. We partner with leading Pharmaceutical and Biotechnology organizations nationwide to build high-impact teams that drive innovation and deliver results.

As a sales-driven organization, we provide a comprehensive range of workforce solutions, including Project Consulting and Delivery, Advisory Solutions, Contractor Engagement, Direct Hire, Contract-to-Hire, and Embedded & On-Demand Project RPO services.

For ambitious graduates and early-career professionals, Harba Solutions offers clear pathways into Sales Management, Account Management, and Professional Recruiting. Joining our team means becoming part of a fast-paced, performance-oriented environment with significant opportunities for career advancement in a hyper-growth company.

Job Description

Within this position, you will be responsible for the full life cycle of our scientific recruitment operations. You will be partnering with various Bio Pharma & Bio Tech companies across the country, to deliver our tailored strategies and best solutions to our clients. It is your responsibility to recruit and build relationships with the top talent in our carefully selected markets. This is a pathway to sales management, account management, or professional recruitment roles within a growing organization.

Job Requirements

• Bachelor’s degree
• Have a genuine passion for entrepreneurship, recruiting, and sales
• High level of business acumen
• Embrace learning and staying curious
• Having excellent interpersonal skills and the ability to empathize
• Competition driven
• Ability to work in an office within a team environment

Compensation Package

• Salary + Commission
• Top-tier competitive commission structure
• Detailed Promotion Planning resulting in higher salaries and title changes
• Health, vision, and dental benefits
• Paid time-off
• Holiday pay