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Open date: October 4, 2025

Next review date: Wednesday, Mar 18, 2026 at 11:59pm (Pacific Time)

Apply by this date to ensure full consideration by the committee.

Final date: Wednesday, Mar 18, 2026 at 11:59pm (Pacific Time)

Applications will continue to be accepted until this date.

The He lab is in the Molecular and Cell Biology department at UC-Berkeley, which encompasses a breadth of disciplines spanning all levels of organization and encompassing diverse organisms. The breath of training, combined with the unique location of Berkeley in the center of biomedical research, offer a nurturing environment for the next-generation scientist to launch on a successful career in biomedical research in academia and industry. The Principal Investigator, Dr. Lin He, was awarded the MacArthur Fellowship (the genius award), the Searle Scholar, a HHMI Faculty Scholar, and is currently a Thomas and Stacey Siebel distinguished chair professor at UC-Berkeley, and a biohub investigator with the Chan-Zuckerberg Initiative (CZI).

The developmental and physiological complexity of a given organism is not governed by the sheer number of protein-coding genes. In mammals, the numerous functional non-coding elements greatly expand gene regulatory modality and diversify functional reservoir. Using human genetics/genomics, mouse genetics/genomics, cell and molecular biology approaches, the He lab at UC-Berkeley has identified a variety of functional non-coding elements, including transposons and non-coding RNAs. Not only do non-coding elements offer important developmental/physiological functions, they also provide us with a unique angle to discover new biological/cellular processes in development and disease. Combining sophisticated genome engineering and innovative live cell imaging, we have pioneered in vivo studies to elucidate the new cellular functions and molecular mechanisms in development and aging. The discoveries of the He lab have been well recognized by publications in prestigious journals, including Nature, Science and Cell. Currently, there are postdoc openings in two projects.

Transposons in mammalian preimplantation development ~40% of mammalian genome originates from transposons, whose abundance greatly exceeds that of protein genes. While historically viewed as degenerated "parasitic" DNAs, transposons yield numerous functional elements for the host genome. These sequences resulted from ancient invasion confer new mechanisms of gene regulation, generate Neogene/ncRNA functions, and provide raw material for genome innovation. Mammalian preimplantation embryos constitute one of the best systems to study transposon-host interactions, as ~20% of their transcriptome results from transposon induction. We aim to characterize the role of specific transposons in preimplantation embryos.

Transposons in aging and disease While specific transposons are integral components of host biology, most mammalian transposons are potentially detrimental to the host genomes, thus inactivated via degenerative mutations and/or transcriptional/post-transcriptional silencing. Interestingly, aberrant transposon induction has been observed in a variety of pathological conditions, including aging, cancer and infection. We aim to investigate the mechanisms underlying transposon dysregulation during reproductive aging and cancer, and to elucidate the effects of transposon-host interactions that accelerate aging and promote cancer.

Postdoc responsibilities:

1) The postdoc will work with the PI to develop a project in one of the two research directions, to comprehensively read literature, to establish appropriate experimental systems, to learn important technologies, and to execute experiments to advance the project and perform data analyses.

2) The postdoc will meet with the PI on a weekly basis to discuss results, to development experimental plans.

2) The postdoc will work with junior lab members to mentor them on specific experimental techniques .

3) The postdoc will contribute to lab duties, which is evenly distributed among all lab members.

Lab:

PhD (or equivalent international degree) or enrolled in a PhD degree program (or equivalent international degree)

Ph.D. (or equivalent international degree) required by the appointment start date. No more than three years of post-degree research experience by the start date.

Ph.D. in developmental biology, Genetics, Genomics, Cell Biology, Molecular Biology, Biochemistry or related field are all welcome to apply. Prior research experiences in mammalian development and disease are preferred.

• Curriculum Vitae - Your most recently updated C.V.

  
  

• Cover Letter

  
  

• Research Statement - Please discuss research accomplishments and proposed plans. This can include, for example, your publication record, awards, presentations, inclusive research practices that promote the excellence of your research, and areas for future research.
  
  (Optional)

  
  

• 3-5 required (contact information only)

Help contact:

UC Berkeley is committed to diversity, equity, inclusion, and belonging in our public mission of research, teaching, and service, consistent with UC Regents Policy 4400 and University of California Academic Personnel policy (APM 210 1-d). These values are embedded in our Principles of Community, which reflect our passion for critical inquiry, debate, discovery and innovation, and our deep commitment to contributing to a better world. Every member of the UC Berkeley community has a role in sustaining a safe, caring and humane environment in which these values can thrive.

The University of California, Berkeley is an Equal Opportunity employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, age, or protected veteran status.

For more information, please refer to the University of California's Affirmative Action and Nondiscrimination in Employment Policy and the University of California's Anti-Discrimination Policy.

In searches when letters of reference are required all letters will be treated as confidential per University of California policy and California state law. Please refer potential referees, including when letters are provided via a third party (i.e., dossier service or career center), to the UC Berkeley statement of confidentiality prior to submitting their letter.

As a University employee, you will be required to comply with all applicable University policies and/or collective bargaining agreements, as may be amended from time to time. Federal, state, or local government directives may impose additional requirements.

Unless stated otherwise, unambiguously, in the position description, this position does not include sponsorship of a new consular H-1B visa petition that would require payment of the $100,000 supplemental fee.

As a condition of employment, the finalist will be required to disclose if they are subject to any final administrative or judicial decisions within the last seven years determining that they committed any misconduct.

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• "Misconduct" means any violation of the policies or laws governing conduct at the applicant's previous place of employment, including, but not limited to, violations of policies or laws prohibiting sexual harassment, sexual assault, or other forms of harassment or discrimination, as defined by the employer.
  
• UC Sexual Violence and Sexual Harassment Policy
  
• UC Anti-Discrimination Policy
  
• APM - 035: Affirmative Action and Nondiscrimination in Employment
  

We areseekingan experienced and forward-thinkingSolution Architect - Data Engineeringto lead the design and implementation of scalable, secure, and high-performance data solutions. The ideal candidate will have deep expertise withPython and SQL, experience with data warehouses (Snowflake or something similar), a strong command ofengineering best practices(includinglinters and code formatters, project organization, and managing environments), and practical experience buildingCI/CD pipelinesto ensure robust, automated delivery of data pipelines and services.

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• Architect Scalable Data Solutions
  Design and implement end-to-end data engineering architectures that are scalable, maintainable, and performant across batch and real-time processing systems.
  

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• Engineering Leadership
  Lead by example with high-quality Python code,utilizinglinters (e.g.,pylint,flake8,black) and enforcing code cleanliness, readability, and best practices across teams.
  

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• CI/CD Pipeline Development
  Build, manage, and optimize CI/CD pipelines using tools such asGitHub Actions,GitLab CI,CircleCI, orJenkinsto automate testing, code quality checks, and deployment of data engineering components.
  

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• Data Governance & Quality
  Establish data validation, logging, and monitoring strategies to ensure data integrity and reliability at scale.
  

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• Collaborate Cross-Functionally
  Work closely with data scientists, software engineers, DevOps, and business stakeholders to translate requirements into technical solutions and ensure alignment with overall enterprise architecture.
  

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• Mentorship & Code Reviews
  Provide guidance to junior developers, lead technical reviews, and enforce clean coding standards throughout the data engineering team.
  

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• 7+ years of experience in software or data engineering, with 3+ years in an architectural or technical leadership role.
  

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• Expert-levelproficiencyinPython and SQL, with a deep understanding of best practices, performance tuning, and maintainable code patterns.
  

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• Proven experience withlinters,formatters, and other static analysis tools to ensure code quality and compliance.
  

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• Hands-on experience designing and implementingCI/CD pipelinesfor data pipelines, APIs, and other backend services.
  

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• Solid knowledge of modern data platforms and technologies (e.g., Spark, Airflow,dbt, Kafka, Snowflake,BigQuery, etc.).
  

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• Strong understanding of software engineering practices such as version control, testing, and continuous integration.
  

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• Experience working in cloud environments (AWS, GCP, or Azure).
  
• Familiarity with Infrastructure as Code (IaC) tools like Terraform or CloudFormation.
  
• Understanding of security, compliance, and governance in data pipelines.
  
• Excellent communication and documentation skills.
  
• Strong leadership presence with the ability to mentor and influence teams.
  
• Problem-solver with a focus on delivering value and simplicity through technology.
  

We offer a Total Rewards package that includes medical and dental coverage, 401(k) plans, flex spending, life insurance, disability, employee discount program, employee stock purchase program and paid family benefits to support you and your family.The salary range for this position is posted below. Where an employee or prospective employee is paid within this range will depend on, among other factors, actual ranges for current/former employees in the subject position, market considerations, budgetary considerations, tenure and standing with the Company (applicable to current employees), as well as the employee's/applicant's skill set, level of experience, and qualifications.

It is the policy of our company to provide equal employment opportunities to all employees and applicants for employment without regard to race, color, ethnicity, gender, age, religion, creed, national origin, sexual orientation, gender identity, marital status, citizenship, genetic information, veteran status, disability, or any other basis prohibited by applicable federal, state, or local law.

Please note this job description is not designed to cover or contain a comprehensive listing of activities, duties, or responsibilities that are required of the employee for this job. Duties, responsibilities, and activities may change at any time with or without notice.

The employer will make reasonable accommodations in compliance with the American with Disabilities Act of 1990. The job description will be reviewed periodically as duties and responsibilities change with business necessity. Essential and other job functions are subject to modification. Reasonable accommodations may be provided to enable individuals with disabilities to perform the essential functions.

For applicants to jobs in the United States: In compliance with the current Americans with Disabilities Act and state and local laws, if you have a disability and would like to request an accommodation to apply for a position with our company, please email .

• Design and implement automated workflows and AI agents for supply chain tasks.
• Conduct iterative testing and user acceptance testing with supply chain teams.
• Configure workflow logic, decision trees, automation sequences, and integration points for AI functionality.
• Develop hybrid solutions integrating analytics dashboards with AI workflows for process automation.
• Document workflow configurations, prompt patterns, and decisions in detail for non-technical user maintenance.

• Expertise in prompt engineering and AI platform management
• Proficiency in no-code/low-code workflow automation tools
• Deep understanding of AI agent training, context windows, model limitations, and hallucination mitigation.
• Basic technical understanding (APIs, data structures, integrations)

This is a highly responsible position that supports the health, safety and welfare of Tribal members and the public. The incumbent in this position is responsible for managing the regulation and inspection of building construction, electrical, mechanical, and plumbing installations and directing compliance and enforcement of all related federal, state and local ordinances of the Seminole Tribe of Florida (STOF). Work involves technical review of all types of construction drawings, plans, and specifications to ensure compliance with applicable codes and ordinances. The incumbent provides general oversight, management, and leadership to building inspectors, plans examiners, and permit technicians as required and is responsible for the issuance of all permits and Certificates of Occupancy in accordance with the Florida Building Code and Tribal administrative policy. The person is also responsible for the administration of the Tribe’s elevator and commercial structure annual inspections programs.

The individual works closely with the Director of the Tribal Inspector’s Department to support all departmental programs and initiatives, including but not limited to the development of the departmental budget and strategic plans, development of building inspections processes and programs, evaluation and improvement of service delivery systems, and administration of the Tribe’s Unsafe Structures Ordinance Program. The incumbent may attend Tribal Council meetings or other community meetings and works with all necessary stakeholders to resolve complaints, address concerns, or solve problems as needed. Bachelor’s degree in Engineering, Building Construction, Civil Engineering, Architecture or related field is required. Master’s degree is preferred. A minimum of ten (10) years of experience as an Architect, Engineer, Building Inspector, Build Code Administrator, or Construction Superintendent with at least five (5) years being in a supervisory capacity is required; or, any equivalent combination of education, experience and training will be considered.

Prior experience with EnerGov software system is preferred. Possession and maintenance of a Building Code Administrator certification by the Florida Building Code Administrators and Inspector’s Board is required. Possession of a valid Florida Driver’s License is required. Must have excellent organizational and interpersonal skills including the ability to clearly communicate complex ideas in English both orally and in writing. Must be able to respond and commit to full duty operations during Hurricane or other emergency events. Demonstrate proficiency with Microsoft software programs. Demonstrate excellent organizational and interpersonal skills including English written and oral communication skills are required. Ability to travel and work a flexible schedule including evenings, weekends and holidays.