Oncology Nurse Practitioner & Sub-Investigator

Nurse Practitioner & Sub-Investigator – Oncology Clinical Research

Location: Los Angeles, CA (various locations)

Employment Type: Full-Time, On-Site

Salary: $200k-300k base salary + bonuses

Overview

We are representing a rapidly expanding, research-focused oncology organization seeking an experienced Nurse Practitioner (NP) to join its high-performing early-phase clinical research team.

This is a full-time role supporting complex oncology trials within a fast-growing, data-driven environment dedicated to cancer therapeutics.

The position is ideal for a Nurse Practitioner with oncology experience who thrives in a hands-on, patient-facing setting and wants to play a key role in advancing early-phase and next-generation immunotherapy programs.

Key Responsibilities

• Deliver comprehensive patient care for oncology clinical trial participants under physician supervision.
• Conduct exams, assess adverse events, manage toxicities, and provide ongoing medical support throughout study participation.
• Participate in subject recruitment, eligibility assessment, and informed consent discussions.
• Serve as a Sub-Investigator on assigned studies, ensuring protocol adherence and safety reporting accuracy.
• Collaborate with physicians, clinical coordinators, and pharmacy teams across multiple early-phase protocols.
• Support long-observation and overnight study patients as required.
• Maintain complete and audit-ready documentation aligned with GCP and sponsor expectations.
• Contribute to continuous improvement in clinical and operational processes as the organization expands.

Ideal Candidate

• Licensed Nurse Practitioner (NP) in California.
• 2+ years of oncology NP experience, ideally with prior RN experience in a hospital or acute-care setting.
• Strong understanding of oncology treatment side effects and supportive care management.
• Clinical research experience is advantageous but not required — full training and mentorship provided.
• Excellent patient management, communication, and teamwork skills.
• Comfortable working in a fast-paced, research-intensive environment.
• Must be committed to a full-time, on-site role.

Why This Opportunity

• Focus on Research — deliver cutting-edge care in a research setting.
• Exposure to Advanced Therapies — including CAR-T, NK cell, bispecific antibody, and targeted oncology programs.
• Collaborative, Mentored Environment — work directly with senior investigators and experienced research leaders.
• Competitive Compensation — strong base salary, performance bonus, and retention incentives.

This search is being managed confidentially by Plexus Partners.

Interested candidates may submit a CV or express interest in confidence to: