Nuvalent Inc Jobs in Usa

WE ARE PDHGROUP

We are a values-driven company that strives to provide the best quality service and products for the construction industry. As a provider and installer of Division 8, Division 10, Division 27, and Division 28 products, our business is built on honesty, integrity, and the ability to get the job completed on-time and with complete customer satisfaction. Our team brings over 425 years of combined experience and includes some of the most knowledgeable people in the industry.

JOB SUMMARY:

As a Project Manager, you will be accountable for the overall direction, coordination, implementation, execution, control and completion of any given project. Additionally, the Project Manager ensures budget and deadlines are met and consistent with project standards.

DUTIES AND ESSENTIAL JOB FUNCTIONS:

• Create a Schedule of Values for our pay applications and submit to the General Contractor.
• Analyze the construction schedule and create a schedule for submittals, material ordering and estimated field labor durations & project completion.
• Create submittals for doors, frames and hardware from architectural plans and specification.
• Manage and respond to electronic contractual changes (RFI’s, PC’s, Etc.). Quote changes that affect our material and/or labor cost. Distribute Change Order Due letters to the contractor.
• Order materials (Purchase orders) from approved submittals for timely delivery according to the construction schedule or as agreed upon with the contractor for billed and stored material.
• Support the Performance Door project field supervisor for the timely delivery of materials according to the construction schedule. Send field use drawings periodically reflecting updated schedules incorporating project revisions.
• Provide monthly pay application to the accounting department including back up documentation for stored or FSC materials.
• Actively pursue contractual “Change Orders” from “price and proceed” CO Due letters. Take an active role in collecting money.
• Approve weekly vendor invoices for payment. Check vendor costs against our purchase order.
• Other job duties and responsibilities as needed.

The Company:
With deep expertise in chemistry, Nuvalent is working to create selective medicines designed with the goal to address the needs of patients with cancer. Nuvalent is an exciting early-stage company, bringing together experienced scientists and industry veterans with a proven track record in drug discovery, oncology drug development, and company building.

This role is field-based, and candidates should live within a reasonable distance from the primary city and state to effectively cover the assigned territory.

The major metro regions for this Southeast territory are Atlanta, Columbus, Valdosta, Gainesville, GA

The Role:

Reporting to the Senior Regional Business Director, the Senior Oncology Account Manager (Sr. OAM) will contribute to Nuvalent's overall sales objective by performing assigned sales-related activities. The Sr. OAM will provide physicians, pharmacists, nurses, and all healthcare professionals (HCPs) with products, services, and approved information that enable them to prescribe Nuvalent's product(s) appropriately.

The Sr. OAM will implement Nuvalent's marketing strategies and execute corresponding plans in a compliant and successful manner to achieve both short-term and long-term objectives. The ideal candidate will be capable of managing the territory and administrative requirements efficiently and effectively while maintaining full compliance with drug laws and regulations when representing Nuvalent and Nuvalent's products to Healthcare Providers.

Responsibilities:

Achieve the assigned sales objective for the territory

• 
  
• Attain the designated goals for calls on appropriate healthcare professionals to communicate balanced, accurate, and complete information on Nuvalent's FDA approved products
  
• Develop and implement a territory business plan to meet customer needs and achieve goals
  
• Navigate through complex external/customer organizational structures, including hospitals, integrated delivery networks (IDNs), group purchasing organizations (GPOs), and healthcare communities, while aligning with cross-functional commercial partners. Be passionate and motivated through headwinds, driving results in the face of adversity.
  
• Demonstrate adherence of administrative requirements, including budget management, expense reports management, CRM call reporting and synchronization, etc., within timelines and company guidelines.
  
• Demonstrate a deep understanding of healthcare professionals (HCP) and account needs, effectively utilizing this knowledge to strategically promote and expand the use of assigned products.
  
• Operate the territory within the assigned expense budget and demonstrate fiscal responsibility.
  
• Comply with all federal, state, and local laws, regulations, and guidelines, including but not limited to the PhRMA Code on Interactions with Healthcare Professionals, as well as complying with all Nuvalent standards and policies relating to all job activities.
  
• Successfully complete training and participation in ongoing updates, including but not limited to product knowledge, disease state, market, selling skills, and compliance.
  
• Assist in the identification and resolution of issues and opportunities while communicating proactively with marketing and sales management. Be disciplined but also willing to challenge norms and processes for continuous improvement. Develop and consistently demonstrate an expert understanding of HCP and Account needs to expand the use of the assigned product appropriately.
  
• Operate with a strong business owner mentality, taking full accountability for territory outcomes.
  
• Candidates must demonstrate rare / ultra rare experience and a willingness to navigate highly specialized, challenging markets. Partner seamlessly with Market Access, Medical Affairs (MSLs), Precision Engagement Managers, and Commercial leadership, collaborating cross-functionally, to deliver integrated customer support. Prioritize the collective success of the team and foster a team-oriented environment.
  
• Utilizing competitive intelligence, identifies and reports shifts in competitor activity, market trends, and customers' needs to inform strategy and use the data deliberately in all aspects of account and territory management.
  
• Show diversity of experience, including a range of skillsets and work at previous companies.
  

Competencies Include:

• 
  
• Customer Focus: Builds deep, trust-based relationships with oncologists, infusion centers, nurses, pharmacists, and other decision makers; consistently demonstrates a patient-first mindset.
  
• Territory Management: Analyzes market data, prioritizes accounts, and executes strategic call planning to maximize impact and coverage.
  
• Influence & Persuasion: Effectively communicates clinical and economic value propositions tailored to the Oncology Market Expertise: Demonstrates a strong understanding of oncology treatment pathways, disease biology, diagnostics/biomarkers, and competitive landscape.
  
• Clinical Fluency: Confidently engages in scientific discussions with HCPs, navigating trial data, MOAs, and real-world evidence.
  
• Compliance & Regulatory Adherence: Operates within promotional regulations (FDA, OIG, PhRMA) and company compliance boundaries while still driving results.
  
• Business Acumen: Understands access, reimbursement, specialty pharmacy distribution, and practice economics to address customer and patient barriers.
  
• Data-Driven Decision Making: Uses CRM, analytics, and market insights to adapt strategy and demonstrate ROI.
  
• Results Orientation: Consistently meets/exceeds sales goals while balancing short-term results with long-term relationship building.
  
• Resilience & Adaptability: Thrives in high-change, high-stakes oncology environment; adjusts rapidly to new clinical data, competitive shifts, or access hurdles.
  
• Problem Solving: Develops innovative solutions for customer challenges (e.g., access barriers, clinical adoption hesitations).
  
• Mentorship & Team Contribution: Coaches peers, shares best practices, and contributes to a high-performance team culture.
  
• Integrity & Credibility: Earns trust through ethical decision-making, transparency, and consistency with company values.
  

Qualifications:

• 
  
• Undergraduate degree is required, ideally in business, marketing, healthcare, life science areas of concentration
  
• 9+ years of successful pharmaceutical/biotech sales experience with 3+ in the oncology/hematology and/or rare disease markets, preferably with oral therapeutic selling experience
  
• Excellent written and oral communication skills
  
• Strong computer skills, notably MS Word, MS Excel, and MS PowerPoint
  
• Periodic overnight travel will be needed for the management of large territories
  
• Occasional evenings and weekend work may be needed for conferences
  

Nuvalent is committed to fair and equitable compensation practices, aiming to provide employees with market-competitive total rewards packages.

The targeted salary range below reflects what Nuvalent reasonably and in good faith expects to offer for this position at the time of posting, but the final salary determination may be within or outside this range based on various factors, including, but not limited to, experience, skills, education, and market factors. The range will be reviewed regularly and is subject to change.

Nuvalent also offers a comprehensive benefit package to support our employees at each stage of their career, financial, health, and well-being journey, including medical, dental, and vision insurance, 401 (k) retirement savings plan, generous paid time off (including a summer and winter company shutdown), and much more.

Nuvalent provides equal employment opportunities (EEO) to all employees and applicants for employment without regard to religion, race, creed, color, sex, sexual orientation, alienage or citizenship status, national origin, age, marital status, pregnancy, disability, veteran or military status, predisposing genetic characteristics or any other characteristic protected by applicable federal, state or local law.

Nuvalent is aware that many companies are dealing with fraudulent job postings on third-party employment search sites and/or individual(s) or entities claiming to be employees of such companies. Those involved are offering fraudulent employment opportunities to applicants, often asking for sensitive personal and financial information, and using such information for criminal activities.

Please be advised that all legitimate correspondence from a Nuvalent employee will come from "@ " email accounts. Automated system response emails from our Greenhouse applicant tracking system come from a " " email address. There are no variations of these email addresses and Nuvalent would not request personal and/or financial information via email. Job opportunities would only be extended after a completed job application is submitted by a candidate and a thorough interview process including 1:1 and/or group interviews via phone, video conferencing and/or in-person.

If you believe you have been contacted by anyone misrepresenting themselves as an employee of Nuvalent, please contact Nuvalent at 857-357-7000. Thank you.

The Company:
With deep expertise in chemistry, Nuvalent is working to create selective medicines designed with the goal to address the needs of patients with cancer. Nuvalent is an exciting early-stage company, bringing together experienced scientists and industry veterans with a proven track record in drug discovery, oncology drug development, and company building.

The Role:

Reporting to the SVP, Drug Safety and Pharmacovigilance, the Senior Director, is responsible for supporting the development and implementation of a risk management system for risk detection, risk assessment and risk minimization for investigational and marketed products. Will oversee risk management plan activities including signal tracking maintenance, ad hoc Health Authority requests and the planning and preparation for aggregate safety reports including DSURs, PADERs and PBRERs for Nuvalent's products.

Responsibilities:

Safety Signal Detection, Evaluation, and Management

• 
  
• Close collaboration with DSPV Safety Physicians to analyze potential safety issues, including signal detection, signal evaluation and signal management. Collaborates proactively with study teams, cross-functional team members, external business partners and vendors to apply knowledge and analytical skills to problems in specific therapeutic areas
  
• Contribute to signaling and data mining activities utilizing internal and external sources of data
  
• Assist in the evaluation of potential safety issues and quality risk assessment reports.
  

Risk Management and Safety Planning

• 
  
• Responsible for coordinating and developing Risk Management Plans for Nuvalent's products among multiple stakeholders
  
• Responsible for patient safety evaluation and development of Safety Management Plans.
  

Safety Governance, Meetings, and Reporting

• 
  
• Contribute to activities related to Nuvalent's safety (governance) meetings, including but not limited to, preparing reports, minutes and meeting documents; ensuring completion of action items; and participating in the discussion of patient safety issues
  
• Manage and support the authoring for aggregate safety reports (e.g., DSUR, PBRER, PADER) in close collaboration with clinical, medical writing and operational functions
  

Process, SOPs, and DSPV Ways of Working

• 
  
• Contributes to the development of SOPs, work practices and guidelines, forms and templates, and other communications related to risk management and product safety.
  
• Responsible for ensuring the global team can anticipate, develop and support improved/consistent scientific ways of working to implement effective PV processes
  

Analytics and Tools

• 
  
• Establish expertise with data visualization tools (e.g., Spotfire)
  
• Contribute as a member of the DSPV team to scenario planning, strategy analysis, portfolio prioritization, budget management and forecasting
  

Leadership and Training

• 
  
• Provide management/mentoring of existing Safety Scientists and training for new staff on PV practices and therapeutic area knowledge
  

Competencies:

• 
  
• Design global risk management frameworks for Nuvalent's medicines
  
• Translate safety data into clinical insights
  
• Adapt visualization tools for safety surveillance
  
• Influence multidisciplinary teams to prioritize patient safety.
  
• Strong ability to build relationships, collaborate and influence across disciplines within Nuvalent and with outside stakeholders
  

Qualifications:

• 
  
• Degree in a medical or healthcare related discipline like MD, PharmD, RN or PhD.
  
• 9+ years' experience in Drug Safety/Pharmacovigilance in a pharmaceutical, biotech company or regulatory agency in similar positions
  
• Excellent knowledge of US and EU drug safety regulations, CIOMS and ICH guidelines
  
• Experience with medical drug safety assessments, drug safety surveillance and monitoring activities
  
• Experience with safety data collection and interpretation from clinical trials, literature and post market
  
• Experience with preparation of responses to Regulatory Authorities and experience with IND/NDA submissions and negotiations with Regulatory Authorities as part of marketing approval
  
• Experience with the development and updates to Reference Safety Information, IB, Company Core Data Sheet and local labels
  
• Excellent verbal, written and presentation skills
  

Additional Information:

Nuvalent is committed to fair and equitable compensation practices, aiming to provide employees with competitive total rewards packages.

The targeted salary range below reflects what Nuvalent reasonably and in good faith expects to offer for this position at the time of posting, but the final salary determination may be within or outside this range based on various factors, including, but not limited to, experience, skills, education, and market factors. The range will be reviewed regularly and is subject to change.

Nuvalent also offers a comprehensive benefit package to support our employees at each stage of their career, financial, health, and well-being journey, including medical, dental, and vision insurance, 401(k) retirement savings plan, generous paid time off (including a summer and winter company shutdown), and much more.

Nuvalent provides equal employment opportunities (EEO) to all employees and applicants for employment without regard to religion, race, creed, color, sex, sexual orientation, alienage or citizenship status, national origin, age, marital status, pregnancy, disability, veteran or military status, predisposing genetic characteristics or any other characteristic protected by applicable federal, state or local law.

Nuvalent is aware that many companies are dealing with fraudulent job postings on third-party employment search sites and/or individual(s) or entities claiming to be employees of such companies. Those involved are offering fraudulent employment opportunities to applicants, often asking for sensitive personal and financial information, and using such information for criminal activities.

Please be advised that all legitimate correspondence from a Nuvalent employee will come from "@ " email accounts. Automated system response emails from our Greenhouse applicant tracking system come from a " " email address. There are no variations of these email addresses and Nuvalent would not request personal and/or financial information via email. Job opportunities would only be extended after a completed job application is submitted by a candidate and a thorough interview process including 1:1 and/or group interviews via phone, video conferencing and/or in-person.

If you believe you have been contacted by anyone misrepresenting themselves as an employee of Nuvalent, please contact Nuvalent at 857-357-7000. Thank you.

The Company:
With deep expertise in chemistry, Nuvalent is working to create selective medicines designed with the goal to address the needs of patients with cancer. Nuvalent is an exciting early-stage company, bringing together experienced scientists and industry veterans with a proven track record in drug discovery, oncology drug development, and company building.

The Role:

Reporting to the Chief Legal Officer, the VP, Compliance, will serve as the company's senior compliance leader, responsible for designing, implementing, and overseeing a comprehensive and effective global healthcare compliance program aligned with applicable laws, regulations, and industry standards. The role is both strategic and hands-on: ideal for a leader who can set vision while rolling up their sleeves to build processes from the ground up. The VP, Compliance will be a trusted advisor to Nuvalent leadership and a partner across business units.

Responsibilities:

• 
  
• Partner with the legal team and key stakeholders to build, implement, and maintain a robust and effective U.S. and global comprehensive healthcare compliance program that is right sized for Nuvalent as it transitions to a commercial organization
  
• Develop, refine and update policies and practices to facilitate global compliance and best practices.
  
• Advise on compliance matters including interpretation and application of Nuvalent's Code of Business Conduct, and Company policies.
  
• Lead implementation of our compliance training program.
  
• Lead implementation of our monitoring and auditing program, oversee audits and monitor the implementation of our compliance operations.
  
• Foster a strong internal compliance, ethics, and "speak-up" culture by creating an environment in which employees see Compliance as a strategic partner
  
• Lead the evaluation, investigation, and resolution of compliance issues/concerns within the organization
  
• Conduct periodic risk assessments and develop and implement a work plan to address risk.
  
• Develop process for and oversee compliance with applicable state and federal transparency and aggregate reporting laws (and non-US country laws, as appropriate) and regulations
  
• Lead and mentor compliance team and ensure appropriate and cooperative allocation of responsibilities.
  
• Serve as a well-respected, credible subject matter expert throughout the organization, with the ability to provide business-oriented, practical guidance
  
• Stay current on new laws, regulations, best practices, and enforcement trends.
  
• Such other responsibilities as assigned from time to time by Chief Legal Officer.
  

Competencies:

• 
  
• A professional leadership presence/demeanor, as well as a highly positive and responsible working attitude
  
• Comfortable working in a fast-paced, results-driven, highly accountable environment, with a demonstrated ability to parallel process multiple projects with competing timelines
  
• Ability to communicate effectively with personnel at all levels of the organization and to inspire confidence and support for compliance initiatives
  
• Demonstrated ability to think strategically and pay close attention to detail
  
• Ability to work collaboratively in teams with a practical, solution-oriented approach
  
• Strong project management skills and ability to handle multiple responsibilities simultaneously and still meet high quality and timeliness standards under pressure
  
• Self-motivated, able to work independently and be reliable, responsible, and accountable
  

Qualifications:

• 
  
• Minimum of 15 years of compliance experience in an organization subject to US pharmaceutical regulations; experience in oncology or rare disease business strongly preferred.
  
• Minimum of 5 years' experience in an ethics and compliance leadership role.
  
• Bachelor's degree required, law degree preferred but not required.
  
• Prior commercial launch experience is essential; experience guiding a company through its initial commercial launch is preferred.
  
• Willingness to travel up to 25% of time and conduct in-person training meetings.
  
• In-depth knowledge of compliance matters related to the launch and subsequent commercialization of branded pharmaceutical products, including a thorough understanding of healthcare laws and regulations and corporate governance issues related to development and commercialization of biopharmaceutical products, including without limitation US Federal healthcare program requirements under the Food, Drug and Cosmetic Act, the False Claims Act, the Anti-Kickback Statute, OIG guidelines and opinions, the Sunshine Act, FCPA. fraud and abuse, transparency, and other healthcare compliance matters
  
• Experience applying a risk-based analysis to compliance issues and demonstrated creativity in developing solutions that satisfy both our requirements and legal obligations.
  
• Ability to serve multiple client groups by recognizing and responding quickly and pragmatically to urgent situations.
  
• Appropriate judgment on when to collaborate with Legal and business colleagues or outside counsel.
  
• Excellent analytical, written, and verbal communication skills with a track record of preparing and delivering effective and engaging presentations and training programs to teams
  

Additional Information:

Nuvalent is committed to fair and equitable compensation practices, aiming to provide employees with competitive total rewards packages.

The targeted salary range below reflects what Nuvalent reasonably and in good faith expects to offer for this position at the time of posting, but the final salary determination may be within or outside this range based on various factors, including, but not limited to, experience, skills, education, and market factors. The range will be reviewed regularly and is subject to change.

Nuvalent also offers a comprehensive benefit package to support our employees at each stage of their career, financial, health, and well-being journey, including medical, dental, and vision insurance, 401(k) retirement savings plan, generous paid time off (including a summer and winter company shutdown), and much more.

Nuvalent provides equal employment opportunities (EEO) to all employees and applicants for employment without regard to religion, race, creed, color, sex, sexual orientation, alienage or citizenship status, national origin, age, marital status, pregnancy, disability, veteran or military status, predisposing genetic characteristics or any other characteristic protected by applicable federal, state or local law.

Nuvalent is aware that many companies are dealing with fraudulent job postings on third-party employment search sites and/or individual(s) or entities claiming to be employees of such companies. Those involved are offering fraudulent employment opportunities to applicants, often asking for sensitive personal and financial information, and using such information for criminal activities.

Please be advised that all legitimate correspondence from a Nuvalent employee will come from "@ " email accounts. Automated system response emails from our Greenhouse applicant tracking system come from a " " email address. There are no variations of these email addresses and Nuvalent would not request personal and/or financial information via email. Job opportunities would only be extended after a completed job application is submitted by a candidate and a thorough interview process including 1:1 and/or group interviews via phone, video conferencing and/or in-person.

If you believe you have been contacted by anyone misrepresenting themselves as an employee of Nuvalent, please contact Nuvalent at 857-357-7000. Thank you.

The Company:
With deep expertise in chemistry, Nuvalent is working to create selective medicines designed with the goal to address the needs of patients with cancer. Nuvalent is an exciting early-stage company, bringing together experienced scientists and industry veterans with a proven track record in drug discovery, oncology drug development, and company building.

The Role:

Reporting to the Associate Director, Corporate Strategy, the Senior Manager, Competitive Intelligence (CI), will support CI activities across Nuvalent's portfolio. CI is a key function within Nuvalent, and this role is a great opportunity to have broad visibility across the organization. The key focus for this role is driver mutated solid tumors, particularly ALK+, ROS1+, and HER2m NSCLC. The role also includes monitoring of the strategies, programs, and capabilities of competitors in research, development, and promotional areas, as well as overall industry trends.

Within this role, you will support decision making, foster a competitive mindset, and collaborate with a broad cross-functional group of therapeutic area partners (including Commercial, Medical Affairs, Clinical, Discovery, Regulatory, and Legal) as well as Senior Leadership. You will be responsible for collecting, synthesizing, and delivering key insights and implications to our business in the competitive environment, related to marketed products, pipeline assets, and external opportunities. These activities are structured around key strategic business questions that you will define in partnership with the Corporate Strategy team and relevant cross-functional stakeholders.

Responsibilities:

• 
  
• Utilizing systematic processes to gather and summarize competitive information that is relevant to Nuvalent's business needs
  
• Providing context and objective analysis of competitive (commercial, clinical, and scientific) information to enable actions and business decision-making
  
• Building and updating databases on competitive landscape
  
• Providing medical conference coverage, some travel may be required
  
• Evaluating and making recommendations on CI tools, processes, and services, and as needed, manage third party agencies/projects to source relevant CI
  
• Presenting key competitive information to teams and leadership throughout the organization through oral and written communication
  
• Participate in the formulation of product/franchise strategies based on data and insights derived from CI, market research, and forecasting analyses.
  

Competencies:

• 
  
• Knowledge regarding the drug development and commercialization process in order to assess and contextualize competitive efforts, particularly in oncology
  
• Ability to interpret and synthesize pre-clinical and clinical scientific data and identify broader implications for our programs and / or specific opportunities.
  
• Strong relationship management skills with internal stakeholders and external contacts and resources.
  
• Proven ability to present at and facilitate small-group and large-group meetings (with peers as well as superiors) to achieve pre-defined objectives.
  
• History of effective written communication skills (including both PowerPoint and Word/email mediums).
  
• Excellent task management skills (specifically project planning, prioritization, objective setting, meeting management and plan execution) are required.
  

Qualifications:

• 
  
• Bachelor's degree or related experience
  
• 3-5 years of experience in pharma/biotech/life sciences consulting
  
• Experience in use of online data sources and scientific/market databases (e.g., PubMed, , TrialTrove, AlphaSense, etc.)
  
• History of independence in researching, formulating, and delivering CI assessments (including basic information as well as strategic insights based on that information).
  

Additional Information:

Nuvalent is committed to fair and equitable compensation practices, aiming to provide employees with competitive total rewards packages.

The targeted salary range below reflects what Nuvalent reasonably and in good faith expects to offer for this position at the time of posting, but the final salary determination may be within or outside this range based on various factors, including, but not limited to, experience, skills, education, and market factors. The range will be reviewed regularly and is subject to change.

Nuvalent also offers a comprehensive benefit package to support our employees at each stage of their career, financial, health, and well-being journey, including medical, dental, and vision insurance, 401(k) retirement savings plan, generous paid time off (including a summer and winter company shutdown), and much more.

Nuvalent provides equal employment opportunities (EEO) to all employees and applicants for employment without regard to religion, race, creed, color, sex, sexual orientation, alienage or citizenship status, national origin, age, marital status, pregnancy, disability, veteran or military status, predisposing genetic characteristics or any other characteristic protected by applicable federal, state or local law.

Nuvalent is aware that many companies are dealing with fraudulent job postings on third-party employment search sites and/or individual(s) or entities claiming to be employees of such companies. Those involved are offering fraudulent employment opportunities to applicants, often asking for sensitive personal and financial information, and using such information for criminal activities.

Please be advised that all legitimate correspondence from a Nuvalent employee will come from "@ " email accounts. Automated system response emails from our Greenhouse applicant tracking system come from a " " email address. There are no variations of these email addresses and Nuvalent would not request personal and/or financial information via email. Job opportunities would only be extended after a completed job application is submitted by a candidate and a thorough interview process including 1:1 and/or group interviews via phone, video conferencing and/or in-person.

If you believe you have been contacted by anyone misrepresenting themselves as an employee of Nuvalent, please contact Nuvalent at 857-357-7000. Thank you.

The Company:
With deep expertise in chemistry, Nuvalent is working to create selective medicines designed with the goal to address the needs of patients with cancer. Nuvalent is an exciting early-stage company, bringing together experienced scientists and industry veterans with a proven track record in drug discovery, oncology drug development, and company building.

The Role:

Reporting to the Research Director, Chemical Development, Associate Director, Chemical Development will apply direct manufacturing experience and chemical engineering tools & principles to support process design, scale up, technology transfer, control strategy verification, and production of small molecule drug substances and related compounds.

The incumbent will provide actionable, technically sound recommendations that strengthen manufacturing robustness and ensure continuity of supply throughout the lifecycle of Nuvalent's products. The incumbent will work directly with the Chemical Development team, and cross-functionally with partners including Quality Assurance, Analytical Sciences and QC, CMC Project Management, Supply Chain, Formulations, and Regulatory Affairs - CMC.

Responsibilities:

• 
  
• Act as main point of contact for CDMOs during late-stage production of regulatory starting materials
  
• Champion deliberate, mindful execution of scale up and technology transfers
  
• Work within a cross-functional team on assigned projects to define or refine a phase-appropriate control strategy, including the identification and justification of critical material attributes, critical equipment attributes, and critical process parameters
  
• Use engineering principles and risk management methodologies to evaluate experimental data or manufacturing performance and identify opportunities for process optimization and improvement throughout the product lifecycle
  
• Troubleshoot production issues and work in cross functional teams to implement effective and persistent corrective/preventative measures
  
• Author, review, and/or edit key CMC and quality deliverables, including (but not limited to): campaign reports, PPQ protocols and reports, tech transfer reports, master batch records, deviation reports, control strategy summaries
  
• Support Reg CMC by reviewing or authoring drug substance sections of various filings, or by supporting Nuvalent responses to health authority questions
  
• Communicate effectively with technical and non-technical stakeholders as required to keep teams abreast of progress, deliveries, timelines, or potential risks thereto
  
• Commit to cGMP principles and Nuvalent's quality system, and maintain the utmost concern for the health of our patients
  

Competencies:

• 
  
• Exceptional interpersonal skills and experience building productive teams and cross functional relationships.
  
• Ability to think critically with strong attention to detail
  
• Demonstrated prioritization capabilities to manage multiple projects simultaneously
  

Qualifications:

• 
  
• Advanced degree in Chemical Engineering with at least 7 years of experience in small molecule drug substance production. Applicants with a bachelor's degree and more extensive experience are encouraged to apply
  
• Hands-on experience in process development (lab and pilot scales)
  
• Experience executing process validation studies
  
• Experience with coordination/management of CDMOs in a virtual paradigm
  
• Expertise in statistical methods, including orthogonal design of experiments, and associated software for data evaluation and decision making
  
• Strong understanding of regulatory guidelines as they pertain to small molecule drug substance manufacturing at an innovator company
  

Additional Information:

Nuvalent is committed to fair and equitable compensation practices, aiming to provide employees with competitive total rewards packages.

The targeted salary range below reflects what Nuvalent reasonably and in good faith expects to offer for this position at the time of posting, but the final salary determination may be within or outside this range based on various factors, including, but not limited to, experience, skills, education, and market factors. The range will be reviewed regularly and is subject to change.

Nuvalent also offers a comprehensive benefit package to support our employees at each stage of their career, financial, health, and well-being journey, including medical, dental, and vision insurance, 401(k) retirement savings plan, generous paid time off (including a summer and winter company shutdown), and much more.

Nuvalent provides equal employment opportunities (EEO) to all employees and applicants for employment without regard to religion, race, creed, color, sex, sexual orientation, alienage or citizenship status, national origin, age, marital status, pregnancy, disability, veteran or military status, predisposing genetic characteristics or any other characteristic protected by applicable federal, state or local law.

Nuvalent is aware that many companies are dealing with fraudulent job postings on third-party employment search sites and/or individual(s) or entities claiming to be employees of such companies. Those involved are offering fraudulent employment opportunities to applicants, often asking for sensitive personal and financial information, and using such information for criminal activities.

Please be advised that all legitimate correspondence from a Nuvalent employee will come from "@ " email accounts. Automated system response emails from our Greenhouse applicant tracking system come from a " " email address. There are no variations of these email addresses and Nuvalent would not request personal and/or financial information via email. Job opportunities would only be extended after a completed job application is submitted by a candidate and a thorough interview process including 1:1 and/or group interviews via phone, video conferencing and/or in-person.

If you believe you have been contacted by anyone misrepresenting themselves as an employee of Nuvalent, please contact Nuvalent at 857-357-7000. Thank you.

The Company:
With deep expertise in chemistry, Nuvalent is working to create selective medicines designed with the goal to address the needs of patients with cancer. Nuvalent is an exciting early-stage company, bringing together experienced scientists and industry veterans with a proven track record in drug discovery, oncology drug development, and company building.

The Role:

Reporting to the Senior Director, HEOR, the Director of Health Economics & Outcomes Research will lead U.S. and Global HEOR strategy for Nuvalent's portfolio, shaping value evidence to enable optimal patient access and inform coverage, reimbursement, and utilization decisions. You will design and deliver HEOR/RWE studies, develop payer-facing economic/decision tools, support pre-, peri-, and post-launch planning, and foster cross-functional collaboration across Medical Affairs, Market Access, Regulatory, Commercial, Clinical Development, and Biostatistics. You'll also play a visible role educating the organization on the evolving U.S. and Global HTA environment.

This is an ideal opportunity for a scientifically strong, execution-oriented leader who enjoys pairing strategic planning with hands-on delivery in a fast-paced setting.

Responsibilities:

Strategy, Governance & Planning

• 
  
• Lead the U.S. & Global HEOR strategy and integrated evidence planning for Nuvalent assets, aligned with Medical Affairs, Market Access, Regulatory, and Commercial priorities.
  
• Standardize and optimize data generation policies, processes, and SOPs to ensure quality, compliance, and scalability.
  
• Develop the annual HEOR tactical plan and budget; manage timelines, vendors, and scope to achieve defined objectives.
  
• Serve as the internal HEOR point of contact for evidence generation needs, services, and technologies; proactively represent payer/IDN evidence needs in cross-functional planning.
  
• Educate and upskill teams on HEOR, evidence-based medicine, U.S. reimbursement trends, and Global HTA dynamics.
  

Evidence Generation & Publications

• 
  
• Design, lead, and complete HEOR/RWE studies (e.g., observational studies, claims/EMR/registry analyses, PRO development/validation, burden of illness, unmet need).
  
• Own research plans, protocols, budgets, and timelines; oversee analyses and author abstracts, posters, manuscripts, and internal reports.
  
• Partner with Clinical Development and Biostatistics/Evidence Generation to optimize study design, endpoints, data sources, and analyses.
  
• Collaborate with Medical Information/Scientific Communications to inform U.S./Global publication plans and ensure consistent, compliant value messaging.
  

Economic & Decision-Support Tools

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• Lead development of AMCP/Global dossiers, Budget Impact Models (BIMs), Cost-Effectiveness Analyses (CEA), ITCs/NMAs, Systematic Literature Reviews (SLRs), and payer pull-through materials.
  
• Support ICER assessments and responses (as applicable) and monitor HTA implications (e.g., NICE, CADTH, etc.) for brand strategy.
  

External Engagement & Field Support

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• Identify and collaborate with KOLs/COEs on study design, authorship, and advisory boards; conduct payer advisory boards to track evolving evidence requirements.
  
• Engage payers, IDNs, PBMs, specialty pharmacies, and other decision makers via compliant scientific exchange to inform evidence needs and communicate value.
  
• Provide field-based scientific/HEOR support and tools to Market Access and medical field teams.
  

Cross-Functional Partnership & Launch Excellence

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• Partner with Brand/Commercial and Market Access to shape value narratives and pull-through while maintaining scientific integrity and compliance.
  
• Contribute to or lead high-priority medical initiatives, integrated evidence planning workshops, advisory boards, and cross-functional launch planning across U.S. and Global teams.
  
• Maintain in-depth knowledge of the evolving healthcare environment and HTA to anticipate evidence needs and inform strategy.
  

Competencies:

• 
  
• Strategic & hands-on: Equally comfortable setting strategy and rolling up sleeves to deliver.
  
• Collaboration & influence: Builds trust and productive relationships with internal leaders and external stakeholders.
  
• Innovation & problem solving: Encourages new ideas; integrates evidence from multiple sources to drive decisions.
  
• Operational excellence: Creates scalable capabilities, processes, and procedures; manages ambiguity and complexity.
  
• Results orientation: Performance-driven; proactively addresses risks, conflicts, and tradeoffs to deliver on time and on budget.
  
• Executive communication: Translates complex science and economics into clear, business-relevant insights.
  

Qualifications:

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• Doctoral degree (PhD, PharmD, MD/DO).
  
• 7-10+ years of relevant pharma/biotech HEOR/RWE experience.
  
• Oncology experience (3+ years), preferably NSCLC; U.S. and Global launch experience.
  
• Demonstrated expertise with U.S. and Global RWD (claims, EMR, registries) and payer landscapes.
  
• Hands-on experience with HEOR modeling (BIM/CEA), observational methods, and PROs; familiarity with statistics.
  
• Proven ability to work independently and collaboratively in fast-paced, cross-functional environments and manage multiple complex projects.
  
• Outstanding communication and presentation skills, including executive-level briefings and external thought leader engagement.
  
• U.S.-based remote role with periodic travel for internal meetings, congresses, advisory boards, and select payer/KOL engagements (~10-20% domestic; occasional international as needed).
  

Preferred

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• Experience supporting ICER and engaging with Global HTA bodies (e.g., NICE, CADTH).
  
• Track record building departmental capabilities, SOPs, and scalable vendor/operational frameworks.
  
• Established relationships across payers/IDNs/PBMs and oncology KOLs/COEs.
  
• Knowledge of medical communications trends and best practices.
  

Additional Information:

Nuvalent is committed to fair and equitable compensation practices, aiming to provide employees with competitive total rewards packages.

The targeted salary range below reflects what Nuvalent reasonably and in good faith expects to offer for this position at the time of posting, but the final salary determination may be within or outside this range based on various factors, including, but not limited to, experience, skills, education, and market factors. The range will be reviewed regularly and is subject to change.

Nuvalent also offers a comprehensive benefit package to support our employees at each stage of their career, financial, health, and well-being journey, including medical, dental, and vision insurance, 401(k) retirement savings plan, generous paid time off (including a summer and winter company shutdown), and much more.

Nuvalent provides equal employment opportunities (EEO) to all employees and applicants for employment without regard to religion, race, creed, color, sex, sexual orientation, alienage or citizenship status, national origin, age, marital status, pregnancy, disability, veteran or military status, predisposing genetic characteristics or any other characteristic protected by applicable federal, state or local law.

Nuvalent provides equal employment opportunities (EEO) to all employees and applicants for employment without regard to religion, race, creed, color, sex, sexual orientation, alienage or citizenship status, national origin, age, marital status, pregnancy, disability, veteran or military status, predisposing genetic characteristics or any other characteristic protected by applicable federal, state or local law.

Nuvalent is aware that many companies are dealing with fraudulent job postings on third-party employment search sites and/or individual(s) or entities claiming to be employees of such companies. Those involved are offering fraudulent employment opportunities to applicants, often asking for sensitive personal and financial information, and using such information for criminal activities.

Please be advised that all legitimate correspondence from a Nuvalent employee will come from "@ " email accounts. Automated system response emails from our Greenhouse applicant tracking system come from a " " email address. There are no variations of these email addresses and Nuvalent would not request personal and/or financial information via email. Job opportunities would only be extended after a completed job application is submitted by a candidate and a thorough interview process including 1:1 and/or group interviews via phone, video conferencing and/or in-person.

If you believe you have been contacted by anyone misrepresenting themselves as an employee of Nuvalent, please contact Nuvalent at 857-357-7000. Thank you.