Information Technology Jobs in Sonoma

Who We Are:

17A is a new type of management consulting firm. We come from places like McKinsey, Palantir, JP Morgan Philanthropies, and venture-backed Healthcare startups. We share a common goal: improving the quality of government and social services. 17A believes that trust in government is something to be continuously built and earned, through strong service delivery.

We have a dynamic core team, and partner with Consultants, known internally as Project-Based Team Members, to bring the best combination of expertise to what we do. Our team has varied skills from a range of industries and experiences, including management consulting, technology and analytics, and public service. If you've spent the early part of your career in consulting or a fast-paced analytical environment and you're ready to apply those skills to something with direct civic impact, 17A is for you.

The Opportunity:

17A is supporting a large Bay Area county agency on a technology and digital services transformation effort. This is a fully embedded, on-site role — not parachuting in. You'll work inside the agency's digital innovation team, sitting alongside Deputy-level leadership to help the county deliver on its mission to make government more human, more responsive, and more digital. This position is a contract role with the potential to convert to full-time after a few months.

This agency has taken a distinctive approach to transformation: rather than buying expensive new systems and hoping for the best, it's doing the hard, human-centered work of dismantling bureaucracy, redesigning how services are delivered, and building a digital culture from the inside. A core initiative — which brings departments through rapid, structured sprints to identify and address service delivery friction — will be a major focus of this role.

This is a chief-of-staff style position for a sharp, early-career operator ready to take on real ownership. You'll help senior leaders turn strategy into action — managing complex initiatives across departments, facilitating working sessions, and communicating progress clearly to executive and operational audiences.

What You'll Do

• Serve in a chief-of-staff capacity to Deputy-level leaders within the innovation team, helping translate priorities into structured plans and concrete next steps
• Support coordination and execution of digital transformation sprints, including logistics, stakeholder engagement, documentation, and follow-through on recommendations
• Facilitate working sessions with department staff and senior leaders to map current-state processes, identify friction points, and co-design improvements
• Lead and coordinate cross-functional workstreams, tracking progress, surfacing blockers, and keeping stakeholders aligned across a large, multi-department organization
• Prepare executive-level communications including briefings, memos, presentations, and decision documents for senior agency leadership
• Conduct rapid research and analysis to support emerging decisions and evolving priorities
• Help build the internal documentation, playbooks, and operational systems the innovation team needs to scale its impact countywide
• Operate as a collaborative, low-ego team member who is genuinely embedded in the agency's culture and mission

Who You Are

You're 1–2 years into your career and you're looking for a role where you can do meaningful work and see the results directly. You might be a current or former:

• Business Analyst or Associate at a management consulting firm
• Fellow or analyst at a public sector-focused organization (e.g., a government innovation lab, a civic tech organization, or a public agency)
• Analyst in a fast-paced, mission-driven environment where you built strong project management and communication muscles

The Skillset:

You'll thrive in this role if you:

• Are energized by the mission — you genuinely care about improving how government works and the people it serves
• Are comfortable operating with ambiguity and building structure where there isn't any yet
• Have strong project management instincts and can keep multiple workstreams moving simultaneously
• Can communicate clearly and credibly with both frontline staff and senior leaders
• Understand that real transformation requires engineering culture, not just deploying technology
• Are ready to be embedded — not just advisory — and want to see the direct impact of your work
• Are based in or willing to relocate to the Bay Area

Bonus if you have:

• Familiarity with local or county government operations
• Experience with digital services, human-centered design, or service delivery improvement
• Prior exposure to process redesign, organizational change, or operational improvement
• Interest in civic technology and the future of public service delivery

Location:

This position is based out of San Francisco, California and you must reside within the area. If you are interested in remote-only opportunities, please consider joining our Network for future roles.

Compensation:

Due to the nature of our business and the clients that we partner with, compensation for this position (and all of our opportunities) depends on the skillset, tenure, and experience that you possess. This specific position has a range of 90,000- 110,000 annually. Depending on the type of work you do with us, you may be eligible to receive medical benefits and other perks.

Accommodation Statement:

Improving public service delivery requires a team with diverse backgrounds and perspectives. We are an equal opportunity employer committed to diversity and inclusion. We prohibit discrimination and harassment of any kind based race, color, creed, religion, national origin, sex, gender identity, sexual orientation, disability, age, marital status, familial status, pregnancy or pregnancy-related conditions, domestic violence victim status, prior arrest or conviction record, military status, predisposing genetic characteristics, membership or activity in a local human rights commission, or status with regard to public assistance.

We encourage and welcome applicants who identify with groups traditionally underrepresented in government to apply.

Please contact , if you would like to request reasonable accommodation during the application or interview process.

Not interested in this specific opportunity but want to make an impact with the work you do? Join our Network for future consulting opportunities within the public service sector!

Key Responsibilities

Business & Revenue Growth

• Own P&L and revenue targets for the Hi-Tech vertical.
• Drive new business (hunting) with global technology, semiconductor, product engineering, and platform companies.
• Expand existing accounts through farming and cross-selling the companies capabilities.
• Identify and build pipeline for large transformation and ER&D deals.

Client & Stakeholder Management

• Act as senior client partner for strategic Hi-Tech accounts.
• Build CXO-level relationships across engineering, product, and digital leadership.
• Position the company as a strategic engineering and technology transformation partner.

Strategic Leadership

• Define go-to-market strategy for the Hi-Tech segment.
• Work closely with delivery, solutioning, and practice teams to create differentiated offerings.
• Drive market expansion in areas like Product Engineering, Digital Engineering, Cloud, AI, Embedded, and Platforms.

Deal & Governance

• Lead large deal pursuits, RFP responses, and commercial negotiations.
• Ensure governance, margin management, and account profitability.
• Track market trends, competitor landscape, and emerging technology opportunities.

Desired Candidate Profile

• 15+ years of experience in Hi-Tech / Product Engineering / Engineering Services.
• Proven track record of hunting + farming with global technology or semiconductor clients.
• Experience managing large strategic accounts and multi-million-dollar portfolios.
• Strong exposure to ER&D, Digital Engineering, Software Platforms, Embedded, Cloud, or AI.
• Demonstrated CXO engagement and large deal closure capability.

Who We Are:

17A is a new type of management consulting firm. We come from places like McKinsey, Palantir, JP Morgan Philanthropies, and venture-backed Healthcare startups. We share a common goal: improving the quality of government and social services. 17A believes that trust in government is something to be continuously built and earned, through strong service delivery.

We have a dynamic core team, and partner with Consultants, known internally as Project-Based Team Members, to bring the best combination of expertise to what we do. Our team has varied skills from a range of industries and experiences, including management consulting, technology and analytics, and public service. If you've spent the early part of your career in consulting or a fast-paced analytical environment and you're ready to apply those skills to something with direct civic impact, 17A is for you.

The Opportunity:

17A is supporting a large Bay Area county agency on a technology and digital services transformation effort. This is a fully embedded, on-site role — not parachuting in. You'll work inside the agency's innovation team, sitting alongside Deputy-level leadership to help the county deliver on its mission to make government more human, more responsive, and more digital. This position is a contract role with the potential to convert to full-time after a few months.

This agency has taken a distinctive approach to transformation: rather than buying expensive new systems and hoping for the best, it's doing the hard, human-centered work of dismantling bureaucracy, redesigning how services are delivered, and building a digital culture from the inside. A core initiative — which brings departments through rapid, structured sprints to identify and address service delivery friction — will be a major focus of this role.

This is a chief-of-staff style position for a sharp, early-career operator ready to take on real ownership. You'll help senior leaders turn strategy into action — managing complex initiatives across departments, facilitating working sessions, and communicating progress clearly to executive and operational audiences.

What You'll Do

• Serve in a chief-of-staff capacity to Deputy-level leaders within the innovation team, helping translate priorities into structured plans and concrete next steps
• Support coordination and execution of digital transformation sprints, including logistics, stakeholder engagement, documentation, and follow-through on recommendations
• Facilitate working sessions with department staff and senior leaders to map current-state processes, identify friction points, and co-design improvements
• Lead and coordinate cross-functional workstreams, tracking progress, surfacing blockers, and keeping stakeholders aligned across a large, multi-department organization
• Prepare executive-level communications including briefings, memos, presentations, and decision documents for senior agency leadership
• Conduct rapid research and analysis to support emerging decisions and evolving priorities
• Help build the internal documentation, playbooks, and operational systems the innovation team needs to scale its impact countywide
• Operate as a collaborative, low-ego team member who is genuinely embedded in the agency's culture and mission

Who You Are

You're 1–2 years into your career and you're looking for a role where you can do meaningful work and see the results directly. You might be a current or former:

• Business Analyst or Associate at a management consulting firm
• Fellow or analyst at a public sector-focused organization (e.g., a government innovation lab, a civic tech organization, or a public agency)
• Analyst in a fast-paced, mission-driven environment where you built strong project management and communication muscles

The Skillset:

You'll thrive in this role if you:

• Are energized by the mission — you genuinely care about improving how government works and the people it serves
• Are comfortable operating with ambiguity and building structure where there isn't any yet
• Have strong project management instincts and can keep multiple workstreams moving simultaneously
• Can communicate clearly and credibly with both frontline staff and senior leaders
• Understand that real transformation requires engineering culture, not just deploying technology
• Are ready to be embedded — not just advisory — and want to see the direct impact of your work
• Are based in or willing to relocate to the Bay Area

Bonus if you have:

• Familiarity with local or county government operations
• Experience with digital services, human-centered design, or service delivery improvement
• Prior exposure to process redesign, organizational change, or operational improvement
• Interest in civic technology and the future of public service delivery

Location:

This position is based out of San Francisco California and you must reside within the area. If you are interested in remote-only opportunities, please consider joining our Network for future roles.

Compensation:

Due to the nature of our business and the clients that we partner with, compensation for this position (and all of our opportunities) depends on the skillset, tenure, and experience that you possess. These specific positions have a range of 90,000- 120,000 annually. Depending on the type of work you do with us, you may be eligible to receive medical benefits and other perks.

Accommodation Statement:

Improving public service delivery requires a team with diverse backgrounds and perspectives. We are an equal opportunity employer committed to diversity and inclusion. We prohibit discrimination and harassment of any kind based race, color, creed, religion, national origin, sex, gender identity, sexual orientation, disability, age, marital status, familial status, pregnancy or pregnancy-related conditions, domestic violence victim status, prior arrest or conviction record, military status, predisposing genetic characteristics, membership or activity in a local human rights commission, or status with regard to public assistance.

We encourage and welcome applicants who identify with groups traditionally underrepresented in government to apply.

Please contact , if you would like to request reasonable accommodation during the application or interview process.

Not interested in this specific opportunity but want to make an impact with the work you do? Join our Network for future consulting opportunities within the public service sector!

Vice President, Regulatory Affairs & Quality

San Francisco Bay Area (Hybrid)

We are partnering with a venture-backed, early-stage medical device company in the San Francisco Bay Area developing a next-generation software-driven surgical platform leveraging AI to transform procedural care.

With strong early momentum and a clear path toward clinical and regulatory milestones, the team is looking to bring on a Vice President of Regulatory Affairs & Quality to build and lead the entire RA/QA function from the ground up.

The Opportunity

This is a true foundational leadership role, reporting directly to the executive team, where you will:

• Own and define the regulatory and quality strategy for a novel AI-enabled medical device platform
• Lead FDA interactions and act as the primary point of contact with the agency
• Drive 510(k) submissions from scratch (including strategy, authoring, and execution)
• Build and scale a fit-for-purpose Quality Management System (QMS) aligned with FDA and ISO 13485
• Partner closely with R&D, Software, Clinical, and Executive leadership to align regulatory pathways with product development
• Prepare the organization for key inflection points including submissions, audits, and early commercialization

What We’re Looking For

• 10–15+ years of experience in Regulatory Affairs / Quality within medical devices
• Proven track record leading 510(k) submissions from concept through clearance
• Strong experience with software-driven / SaMD / AI-enabled technologies
• Deep understanding of FDA regulations, design controls, and QMS implementation
• Prior experience in an early-stage or startup environment (highly preferred)
• Demonstrated ability to operate as a hands-on leader and strategic partner

Why This Role

• Opportunity to own and build the RA/QA function from zero
• Work directly with an experienced leadership team and investors
• Be part of a company tackling a high-impact clinical problem with differentiated technology
• Significant influence on regulatory strategy, product direction, and company trajectory

Role: Engagement Manager– Digital Health Experience

Location: Remote (U.S.)

Duration: 6-Month Contract

Working Time Zone: PST (Pacific Time Zone)

Position Overview

We are seeking a Engagement Manager– Digital Health Experience to lead the deployment, adoption, and engagement optimization of mobile digital health applications within the U.S. healthcare ecosystem. This role requires a hands-on professional with strong experience in launching digital health platforms, managing deployments, and driving sustained patient engagement through data-driven engagement strategies.

The ideal candidate will have experience deploying consumer-facing healthcare applications used by patients across providers and payer organizations, while leveraging engagement tools and analytics platforms to improve patient adoption, retention, and usage metrics such as DAU/MAU.

This role will work closely with product, engineering, digital marketing, and care management teams to ensure successful rollout of mobile applications and to design engagement loops that increase patient participation and long-term platform usage.

Key Responsibilities

• Lead deployment and rollout of mobile digital health applications across healthcare provider or payer environments.
• Manage end-to-end implementation and project management of digital health platforms, ensuring successful launches and smooth adoption by patient populations.
• Design and implement patient engagement strategies and engagement loops to drive consistent application usage and retention.
• Utilize engagement platforms such as , Intercom, Mixpanel, or similar tools to design communication workflows, patient messaging, and engagement campaigns.
• Monitor and optimize digital engagement metrics, including DAU, MAU, retention rates, and user engagement trends.
• Analyze user behavior data and analytics to improve patient onboarding, engagement journeys, and digital experience.
• Collaborate with product, analytics, and engineering teams to continuously enhance patient engagement features and workflows.
• Coordinate with healthcare stakeholders to ensure digital tools align with clinical workflows and patient care programs.

Required Qualifications

• Strong experience in deploying and managing digital health applications within healthcare provider or payer environments.
• Hands-on experience in project management and platform implementation for consumer-facing digital products.
• Experience driving user engagement, retention, and adoption for mobile or digital applications.
• Familiarity with engagement platforms such as , Intercom, Mixpanel, or similar customer engagement and analytics tools.
• Experience tracking and optimizing digital engagement metrics such as DAU, MAU, retention, and user lifecycle engagement.
• Strong analytical and problem-solving skills with the ability to translate data insights into engagement improvements.

Preferred Qualifications

• Experience working within digital health, healthcare technology, or healthcare consumer platforms.
• Familiarity with healthcare ecosystems including provider systems, payer platforms, and patient engagement solutions.
• Experience integrating engagement tools with mobile health applications or digital health platforms.
• Background working with health systems, health plans, digital health startups, or healthcare technology consulting firms.

Job Description:

Mandatory to have working experience as SRE manager especially in Retail domain application support ( NOT CLOUD /DevOps)

Must have working knowledge on SRE principles such as Logs, metrics, availability metrics, uptime, ticket tracking, e-com services, ITIL framework specifically on Alerts, Incident, change management, CAB, Production deployments, Risk and mitigation plan, SLA, SLI, SLO

Hands on experience in Monitoring, Logging, Alerting, Dashboarding, and report generation in any observability tools Prefer DataDog or other tools such as Splunk/Dynatrace/ELK/Grafana). This engagement is a customer using Dynatrace,Splunk, PagerDuty hence it is good to have this expertise

Mandatory to have work experience in leading Level 2/Level 3 application support team based out of IND who provide 24x7 coverage.

Should know how to gather & communicate SRE requirement from customers and define SRE roadmap.

Working experience on how to gather requirements on health of applications, services to monitor, setting service levels.

Must have good knowledge on eCommerce platforms in microservice architecture, Sterling OMS , Retail Applications like XStore.

Should be able to lead P1 calls, brief about the P1 to customer, proactive in gathering leads/ customers into the P1 calls till RCA, PIR etc.

Should have knowledge on building process , framework by following ITSM principles, SOP, runbooks, handling any ITSM platforms (JIRA/ServiceNow/BMC Remedy)

Must know how to work with the Dev team, cross functional teams.

Should be able to generate WSR/MSR by extracting the tickets from ITSM platforms, present to customers and client leaders.

Manage overall SRE delivery, customer focus mindset , closely work with customer leaderships.

Preferred:

Be a client face at customer site collaborating with client leadership.

Ability to clearly communicate and understand a technical idea/concept.

Ability to work in a professional environment while interacting with peers and stakeholders, collaborating with offshore teams.

Excellent written and verbal communications skills.

Motivated, goal driven, influential, innovative, curious, and open minded, fun to work with, collaborator.

Capability to work with people in different time zones.

Ability to operate in a fast-paced, evolving environment and appropriately prioritize tasks, and keep abreast of the latest technology.

Collaborate with cloud architecture, infrastructure team, project management team, and technology services, management team.

Create and maintain detailed documentation.

At Amazfit, design and technology move together.

We create smart wearables that blend elegant form, human-centered function, and cutting-edge innovation — from performance-driven sports watches to lifestyle products that express personal style.

Our mission is simple: help people live healthier, more connected lives through design that feels natural, looks beautiful, and works effortlessly.

Join our passionate design team, where creativity, craftsmanship, and technology come together to shape the future of wearables.

What You’ll Do:

As an Industrial Designer, you’ll take ideas from concept to production — shaping next-generation wearables that define Amazfit’s design identity. You’ll collaborate across disciplines including product management, UX, engineering, and marketing to bring bold, refined ideas to life.

• Create inspiring design concepts through sketching, 3D modeling, and visual storytelling
• Develop details across CMF, ergonomics, and manufacturability with precision and creativity
• Collaborate with mechanical and manufacturing partners to ensure design intent through production
• Explore new materials, finishes, and trends to keep Amazfit products ahead of the curve
• Present ideas clearly through visuals, mockups, and prototypes
• Contribute to the evolution of Amazfit’s design DNA and product strategy

What We’re Looking For:

• 4+ years of experience in industrial/product design (wearables, lifestyle, or consumer electronics preferred)
• A portfolio showcasing creative process, aesthetic sensitivity, and production-ready design
• Proficiency in SolidWorks, Creo or Rhino, KeyShot, and Adobe CC
• Strong understanding of CMF, DFM, and real-world manufacturing constraints
• Deep sense of aesthetics and style, able to contribute to female-oriented design such as rings or jewelry-related projects
• Experience or background in jewelry design is highly preferred
• Proactive, open-minded, and passionate about design and innovation
• Comfortable working in a collaborative, cross-functional environment
• Bachelor’s degree in Industrial Design or equivalent

Bonus Points:

• Experience designing wearable or sports-related products
• Skills in graphic, motion, or interaction design
• Understanding of UI/UX principles

Benefits of Working At Zepp Health:

• Competitive salary, Vacation day, sick day
• Health insurance, Vision insurance, Dental insurance, life insurance
• 401K & Matching
• Year-end Bonus pay
• Other Benefits

Zepp Health is an Equal Opportunity employer and welcomes everyone to our team. If you need reasonable accommodation at any point in the application or interview process, please let us know. In your application, please feel free to note which pronouns you use (for example: she/her/hers, he/him/his, they/them/theirs, etc).

About Straia

At Straia, we’re building the AI-native intelligence layer for colleges and universities.

Today, colleges run on dozens of disconnected systems, forcing staff to spend hundreds of hours manually reconciling data, compiling reports, and tracking down insights. Straia changes that. We unify institutional data and layer on AI agents that answer questions, generate insights/visualizations, and automate repetitive workflows, transforming how colleges operate.

Over time, Straia will evolve into the core intelligence layer for institutional operations, where every function, from student advising to admissions to budgeting and resource planning, is supported by collaborative AI agents that understand each institution’s unique data landscape.

We recently raised our pre-seed from a16z, Reach Capital, and JFF Ventures, and are now hiring a founding backend engineer to help build the technical backbone of how institutions interact with their data.

The Role

As a Founding Engineer at Straia, you’ll work directly with a small team including directly with our CEO (Ryan), CTO (Alan) and CPO (Nikki) to design, build, and scale the core infrastructure of our platform.

This is a 0 → 1 opportunity to shape not just the product, but the engineering culture, architecture, and trajectory of the company. You’ll ship fast, make key technical decisions, and help define how AI can power the next generation of enterprise data intelligence.

We’re specifically looking for someone who consistently raises the bar. The kind of engineer whose default speed and judgment increase the velocity of everyone around them. If you thrive when expectations are high and the pace is fast, you’ll feel right at home

What You'll Do

• Build the core platform — architect and implement services spanning data ingestion, query orchestration, and agentic AI workflows
• Ship end-to-end features across our React + Node.js + Postgres stack, integrating directly with LLMs like GPT, Gemini, and Claude
• Scale infrastructure on GCP for performance, reliability, and data security
• Collaborate with users (university data teams and administrators) to translate real problems into elegant, powerful solutions
• Lay the foundation for Straia’s engineering culture, best practices, and technical roadmap
• Prototype fast, iterate faster — your work will directly shape how education leaders experience AI in their daily decision-making

Who You Are

• 4–7 years of experience building and shipping full-stack applications, with a strong emphasis on backend systems (Node.js, TypeScript, Postgres).
• Deeply technical, with a track record of building scalable, high-quality software
• Startup-minded — you thrive in ambiguity, love building from scratch, and see constraints as creative fuel
• Mission-driven — excited to improve education through technology that makes institutions smarter, faster, and more equitable
• Collaborative and high-agency — you take initiative, value clear communication, and have the instincts of an owner, not an employee
• AI-curious or experienced — exposure to LLMs, vector databases, or prompt engineering is a plus

Our Stack

• Frontend: React + Vite
• Backend: Node.js + Express, orchestrating data and AI agent workflows
• Data Layer: Postgres + Caching for fast queries
• LLM Integration: GPT, Gemini, Claude via API
• Cloud & Infra: Hosted on GCP

Why Join Straia

• Be one of the first engineers at a venture-backed AI company redefining institutional intelligence in higher ed
• Shape the core architecture and engineering culture from day one
• Work directly with top-tier investors and advisors from a16z, Reach, and JFF Ventures
• Join a small, fast-moving team that works incredibly hard, ships fast, and still makes time for good food, laughs, and adventures — we take our work seriously, but not ourselves
• Build meaningful technology that directly impacts student success and equity across colleges nationwide

What We Offer

• Compensation: $160K–$225K + equity
• Location: San Francisco (in office 4 days a week)
• Benefits: Health (platinum insurance), dental, and vision

**We do not sponsor Visas**

Pacific International has been exclusively retained by a global leader in the development and production of consumer electronic components, enabling their customers to innovate and expand capabilities.

As they have sustained themselves as a global market leader, they are looking for an Account Director to further expand their reach in the consumer electronics industry. This is a highly visible position with the opportunity to build and deploy strategies for a global organization.

Key Responsibilities

• Lead customer strategy, serving as the primary point of contact and building strong cross‑functional relationships while overseeing commercial and technical initiatives.
• Identify new technology opportunities, expand engagement across business units, and pursue growth with additional OEMs by aligning solutions to customer roadmaps.
• Coordinate with global engineering, operations, and program teams to drive successful development from concept through mass production.
• Lead pricing negotiations, contract and agreement reviews, and annual planning to drive revenue growth while ensuring profitability and long‑term alignment.
• Monitor market trends, emerging technologies, and competitive activity to guide strategy.
• Maintain accurate forecasting, pipeline visibility, and account documentation using CRM and internal tools.

Ideal Candidate Profile

• Bachelor’s degree in engineering, Business, or a related field
• 7-10+ years of sales experience in the consumer electronics or electronic component industry.
• Direct experience managing relationships with consumer electronic OEMs is required.
• Experience managing global customers,
• Proven ability to manage multi-stakeholder accounts within the consumer electronics industry.

About Pacific International Executive Search:

Pacific International, a globally recognized retained executive search firm, is dedicated to empowering Fortune 500, FTSE 100, and high-growth enterprises in building exceptional C-suite, senior-level, and strategic leadership teams while championing diversity and inclusion. Our adaptability, agility, and forward-thinking ethos distinguish us in the ever-evolving business landscape.

Since 1997, we have been dedicated to building lasting client partnerships based on trust and reliability, and a proven track record of successful C-suite and mid- to senior-level leadership project delivery across many key industries globally.

Diversity Statement:

At Pacific International, diversity, equity, and inclusion are at the core of who we are and what we do. Our commitment to these values is unwavering and we proudly champion diversity on behalf of our clients in every Executive Search mandate we undertake. Employment decisions are made without regard to race, color, religion, national or ethnic origin, sex, sexual orientation, gender identity or expression, age, disability, protected veteran status, or other characteristics protected by law. In pursuit of these objectives, we actively encourage applications from individuals of all backgrounds and identities.

Amber Bio is a biotechnology company pioneering new gene editing modalities using multi-kilobase edits to reach previously undruggable patient populations. Founded by pioneers in the CRISPR field from leading institutions for gene editing research, the company is developing a first-of-its-kind RNA editing platform that can correct thousands of bases at once, thereby correcting genetic mutations safely and reversibly. If you are interested in building a new frontier in genetic medicine, we welcome you to apply.

Job Description: High-Throughput Screening Research Associate II, III (Biodesigner II, III)

Responsibilities:

• Perform massively parallel reporter assays and high-throughput screens across diverse cellular contexts using cellular and molecular readouts.
• Develop and execute molecular biology workflows such as vector design and cloning, DNA/RNA extraction, RT-PCR, qPCR, and next-generation sequencing.
• Support cell culture activities and experiments in multiple cell lines, at small and large scales.
• Design and execute cell-based assays (AAV/lentiviral transduction, transfection, flow cytometry, immunostaining, and other plate reader assays).
• Engineer and characterize cell-based systems using synthetic biology tools and techniques.
• Conduct and troubleshoot experiments, independently and in collaboration with colleagues, to optimize screening throughput, sensitivity, and specificity.
• Proactively troubleshoot technical issues and recommend potential corrective actions based on personal observations and literature searches.
• Prepare summaries of data and present internally to colleagues and management.
• Draft SOPs, follow protocols, diligently document experimental data in lab notebooks, and organize and maintain electronic work records.
• Author scientific reports and data summaries.
• Collaborate with cross-functional teams to meet project goals, bridging early discovery with high-throughput screens to nominate and optimize candidates for further characterization.

Qualifications:

• Bachelor’s or Master’s degree in Biology, Biochemistry, Chemical Engineering, Biological Engineering, or a related field.
• At least 2 years of industry wet lab experience.
• Mammalian cell culture experience (culturing, transfecting and transducing cells, and DNA/RNA purification from cells).
• Molecular biology expertise (vector design and cloning, qPCR, primer and probe design, DNA/RNA extraction workflows)
• Critical thinker with excellent communication skills who thrives in a multidisciplinary, fast-paced team environment.
• Strong written and verbal communication skills.

Preference will be given to those who display:

• High throughput screening assay development in an industry setting.
• High motivation, with a strong work ethic and dedication to generating impact.
• Attention to detail, with the ability to extract deep insights from data.
• First-principles thinking, and an ability to refine one’s intuition based on additional data.
• Ability to go from ideation to data in an independent fashion.
• Long-term personal vision with defined career goals.
• High EQ with team-oriented thinking.
• Experience with pooled, high-throughput screens using next-generation sequencing-based readouts, and/or preparing screening plasmid libraries from synthesized oligo arrays.
• Experience with CRISPR-Cas systems and/or gene editing and delivery technologies.
• Experience preparing next-generation sequencing libraries (Illumina, PacBio, and/or Nanopore platforms).

If you have a passion for advancing gene editing technologies and desire to be part of a pioneering biotech company, we encourage you to apply and join our ambitious team.

Please apply directly through LinkedIn.

Amber Bio is an equal-opportunity employer and encourages applications from candidates of diverse backgrounds. We value diversity and are committed to creating an inclusive and supportive work environment for all employees.