Information Technology Jobs in Pacifica, CA

Amber Bio is a biotechnology company pioneering new gene editing modalities using multi-kilobase edits to reach previously undruggable patient populations. Founded by pioneers in the CRISPR field from leading institutions for gene editing research, the company is developing a first-of-its-kind RNA editing platform that can correct thousands of bases at once, thereby correcting genetic mutations safely and reversibly. If you are interested in building a new frontier in genetic medicine, we welcome you to apply.

Job Description: Research Associate III/ Senior Research Associate (Biodesigner), Assay Development / Bioanalytical Development

Position Overview: The Research Associate III/ Senior Research Associate in Assay Development and Bioanalytical Development will play a critical role in the development, qualification, and validation of bioanalytical methods to support our RNA editing programs. The successful candidate will work under the guidance of an assay development scientist to develop custom assays for the analysis of samples, including AAVs, cells, and tissues. This role also involves drafting key documents such as Standard Operating Procedures (SOPs) and method development reports.

Key Responsibilities:

• Method Development, Qualification, and Validation:
• Support the development, qualification, and validation of bioanalytical methods in accordance with regulatory guidelines.
• Develop, optimize, and execute robust bioanalytical methods for the characterization, release, and stability testing of Amber's gene therapy.
• Sample Analysis:
• Support drug absorption, distribution, metabolism, and excretion studies.
• Perform analysis of AAVs, cells, and tissues to support various stages of research and development.
• Lead efforts to streamline and optimize sample storage and processing, as well as establishing and maintaining critical reagent stocks and cell banks.
• Documentation Reporting:
• Draft and review key documents such as SOPs, method development, and sample analysis reports.
• Maintain accurate and detailed records of all experiments and analyses.
• Collaboration & Communication
• Collaborate with manufacturing and preclinical teams to support pipeline needs.
• Communicate and present findings clearly to internal stakeholders.

Qualifications:

• B.A./B.S. or M.S. in Molecular Biology, Biochemistry, Analytical Chemistry, or a related field.
• 3+ years of experience in bioanalytical and assay development in the biotechnology or pharmaceutical industry.
• Demonstrated strong proficiency in a wide range of molecular biology techniques such as molecular cloning, DNA/RNA extractions, RT-qPCR, ddPCR, and ELISA.
• Experience with cell-based assays and detection methods such as fluorescence, luminescence, and ECL.
• Hands-on experience using laboratory automated systems (e.g., liquid handlers, extraction robotics, etc.).
• Background in RNA-based therapies is highly desirable.
• Experience writing SOPs and reports supporting IND filings (e.g. development, qualification sample analysis reports, etc.)
• Knowledge of FDA and ICH guidelines for method development, qualification, and validation.
• Prior history in compiling and analyzing data and generating reports that are routinely presented to project teams.
• Ability to work effectively in a collaborative, fast-paced environment.

Preference will be given to those who display:

• High motivation, with a strong work ethic and dedication to generating impact.
• Attention to detail, with the ability to extract deep insights from data.
• Ability to go from ideation to data in an independent fashion.
• Long-term personal vision with defined career goals.
• Team-oriented thinking.
• Demonstrated excellence in small team environments, including a “no task is too small” attitude.

If you have a passion for advancing gene editing technologies and desire to be part of a pioneering biotech company, we encourage you to apply and join our ambitious team.

Please apply directly through LinkedIn.

Amber Bio is an equal-opportunity employer and encourages applications from candidates of diverse backgrounds. We value diversity and are committed to creating an inclusive and supportive work environment for all employees.

Local candidates only. You must be a W2 employee and we can not work with third party clients.

Software Engineer – Generative AI Applications |

Company’s Early Clinical Development (ECD) team is looking for a Software Engineer to design and build next‑generation applications that integrate generative AI into clinical development workflows. You’ll work with AI scientists, full‑stack engineers, and cross‑functional partners to deliver innovative, user‑centric tools that support Clinical Science, Operations, Medical Writing, Regulatory, and Quality teams.

What You’ll Do

• Develop and deploy software that integrates LLMs and AI‑driven capabilities
• Build intuitive front‑end interfaces and scalable backend services
• Design and maintain RESTful APIs and deployment pipelines
• Write clean, well‑documented, testable code; participate in code reviews
• Stay current on AI/ML advancements and evaluate new technologies
• Collaborate with data scientists, engineers, and product teams to embed AI into clinical development tools
• Monitor production systems and optimize performance

Who You Are

• Full‑stack engineer with strong experience building AI‑enabled applications
• Deep understanding of modern AI/LLM capabilities, limitations, and best practices
• Strong communicator who can work across scientific and technical teams

Minimum Requirements

• Bachelor’s or Master’s in CS, Engineering, Math, or related field
• 5+ years full‑stack development experience
• Expertise with Vue.js or React, plus backend frameworks (FastAPI, Django, Flask, Next.js)
• 2+ years building or deploying AI/ML applications
• Experience with REST APIs, prompt engineering, and containerized workflows (Docker, Kubernetes)
• Strong automated testing skills (unittest, jest, Playwright)
• Familiarity with Agile development
• Experience with AWS, Snowflake, and scalable system design
• Experience integrating LLMs, RAG systems, or chatbots

Preferred

• Experience with LLM fine‑tuning, AI agents, HuggingFace, LangChain, TensorFlow, or PyTorch
• Experience with Office.js add‑ins, WebSockets, JWT, or CRDTs (Yjs)
• Background using NLP/LLMs on clinical text or knowledge of clinical development

NIBBI SUMMARY

Nibbi Brothers has been a member of the Bay Area’s construction community since 1950. The Company is known for its integrity, innovation, quality and contributions to the communities in which it works. Nibbi’s safety program often exceeds federal and state requirements, demonstrating that the safety and wellbeing of everyone associated with our projects is the highest priority. Core markets include commercial, civic, seismic retrofits, historic restoration, waterfront structures, education, housing, hospitality, and community-based facilities. Nibbi self-performs production framing and structural concrete. Our projects range in size from $5 million to over $200 million.

Nibbi provides its people with comprehensive benefits and opportunities for career development. We encourage continuing education at all levels. We are proud of our friendly, family culture that is based on respect, collaboration and a strong work/life balance.

POSITION SUMMARY

The Project Manager’s primary responsibility is to manage, in collaboration with the Superintendent, the successful completion of assigned projects. The Project Manager is the lead for project financials, risk management, and client relations. Occasional travel is required. This position reports to the Project Executive.

ESSENTIAL FUNCTIONS

• Manage financials, risk management, and client relations of assigned projects from pre-construction to closeout.
• Ensure Nibbi’s standards of safety and quality are adhered to by assertively championing Nibbi’s safety culture to project team and subcontractors.
• Mentor and develop field team members while effectively managing the overall team.
• Work collaboratively with Superintendent, project team members, and field.
• Represent Nibbi in a professional manner.

RESPONSIBILITIES

• Manage the field and project team successfully and collaboratively.
• Establish and maintain positive and effective relationships with clients, Construction Managers, project team, consultants/architect/engineers, subcontractors, adjacent community, trade unions, and governmental agencies.
• Actively participate in project buy-out and formalizing subcontractors.
• Review all project documents, including project submittals, RFIs, and shop drawings, for completeness and accuracy.
• Collaborate with the Pre-Con department to write and ensure execution of all subcontracts and purchase orders.
• Assist Superintendent with initial project set-up including site logistics.
• Create and enforce a site-specific emergency action plan for assigned projects in collaboration with the Superintendent.
• Use project management and scheduling software consistently and accurately.
• Responsible for managing project financials, billings, and cost procedures.
• Responsible for the financial oversight of field labor.
• Conduct team meetings, owner/architect meetings, and safety audits.
• Produce project specific status job status review reports.
• Manage project closeout.
• Attend company and industry events including meetings, trainings, workshops, etc.
• Other related duties as assigned or needed.

QUALIFICATIONS

Degree in Construction Management, or related field, and 4-5 years of experience as an Assistant Project Manager, or equivalent role, in the construction industry. The ideal candidate will have experience with apartment complex construction rehabilitation projects. Candidates must have a solid understanding of the construction industry, job site safety requirements, contract management, planning and scheduling, budgets, building products, and relevant technology. This position requires a high level of fluency reading plans, specifications, and related project documents. Key competencies are leadership, initiative, communication, teamwork, managing for results, and coaching & mentoring.

Technical Skills: ProCore, Tekla, On-Screen Take-off, Primavera P6, MS Office Suite.

PHYSICAL DEMANDS

The physical demands described here are representative of those that must be met by an employee, with or without reasonable accommodation, to successfully perform the essential functions of this job. While performing the duties of this job the employee may be exposed to conditions that include weather such as heat and/or humidity and cold, fumes or airborne particles, exposure to dust and asphalt, and moving mechanical parts. There may be occasional exposure to toxic or caustic chemicals. Conditions can also include risk of electrical shock and risk of vibration. The noise level in the work environment can often be loud.

The Project Manager is regularly required to:

• Walk, climb stairs, sit, and stand.
• Talk and hear at normal levels.
• See with close vision, distance vision, color vision, peripheral vision, depth perception, and have the ability to adjust focus.
• Reach with hands and arms.
• Use hands and fingers to operate tools and other business machines.
• Lift and/or move up to 50 lbs.

COMPENSATION & BENEFITS

Comprehensive medical, dental, and vision

Flex plans

Life insurance

Supplemental insurance plans

401K with employer matching

Vehicle allowance

PTO

Holidays

Incentive compensation bonus

Educational reimbursement

Student loan repayment assistance

The expected salary range for this role is between $135,000 and $140,000 annually, depending on experience.

Nibbi Brothers is an Equal Opportunity Employer. We do not discriminate on the basis of race, religion, color, sex, gender identity, sexual orientation, age, disability, national origin, veteran status or any other personal characteristic protected by law. Employment decisions are made on the basis of qualifications, merit, and business need.

Must be authorized to work in the US now and in the future without employer sponsorship. Nibbi Brothers uses E-Verify.

Contractor’s License #757362

We’re looking for a highly intelligent, strategic, and driven individual with exceptional communication skills and organizational abilities to join our team as a deputy chief of staff / executive personal assistant to a busy tech founder with a young family. This role will report to and work closely with the Chief of Staff to serve as the right-hand of the Principal and his family across all facets of their domestic office and household affairs. In this capacity, the ideal candidate will be able to seamlessly balance and transition from critical strategic initiatives and projects that help the Principal and family scale to the various day-to-day tasks required to keep the household running smoothly. Searching for a high-performer that is looking for longevity and the ability to grow rapidly in a dynamic environment and be part of a tight-knit team.

Critical Requirements / Attributes:

• LOCAL CANDIDATES ONLY - can easily be on-site in Lafayette/Orinda area when needed
• 5+ years of experience supporting executives in a complex, high-paced environment, ideally having worked in a private/family office setting
• Bachelor's or advanced degree from a highly-rated institution with evidence of intellectual distinction
• Strategic operator with the ability to develop clear plans across near, medium and long term horizons and then develop a plan to execute on said strategy
• Extremely strong research, reasoning, and analytical skills demonstrated in a professional setting
• Impressive ability to communicate clearly and concisely, both verbally and in writing
• Very technically savvy; not just with standard productivity tools (e.g., Office/Excel) but modern AI apps and the aptitude to pick up new technologies as well
• Maniacal attention to detail, incredible organizational skills, and proactivity are absolutely paramount requirements for this role
• Wired with a "move fast and get it done" mindset for any task - big or small - that can come up with creative solutions on the spot to challenges that may arise
• High EQ with great interpersonal skills and ability to operate in a tight-knit team environment
• Excellent references with demonstrated longevity at previous roles

Responsibilities include (but are not limited to):

• Spearheading various strategic initiatives for Principal - including requirements specification, strategy design, and execution plan
• Assessing overall support needs of the Principal and family and putting in place workflows/processes to streamline and simplify operations
• Handling tasks of a highly confidential nature with the utmost discretion and professionalism
• Researching, organizing and arranging travel for the family, including flights, accommodations, transportation, activities, etc.
• Conducting research and executing on various topics related to lifestyle and philanthropic needs, children's activities, etc
• Overseeing Principal and family calendars, including scheduling appointments, meetings, and events
• Identifying need for various advisors / vendors, researching / screening options, and managing / hosting vendors as necessary
• Building and maintaining positive relationships with all stakeholders, including family members, staff, vendors, and contractors

Logistics:

• Full-time Monday-Friday but flexibility to occasionally work after hours / weekend
• Predominantly remote but with ability to be on-site at family home (Lafayette / Orinda area) when needed
• LOCAL CANDIDATES ONLY

Compensation:

• $100K+ per year | DOE
• Health benefits
• Paid vacation / sick days / holidays
• Annual performance and salary review
• Discretionary bonus

Commercial Legal Analyst | Leading AI Company| San Francisco, CA | Hybrid Contract — 6 Months | $55–$65/hr

About the Role

A fast-moving, high-profile AI company is hiring a Commercial Legal Analyst to support contract negotiations across the business, from NDAs and vendor agreements to complex strategic partnerships. You will work closely with teams across Sales, Finance, Marketing, and Research, gaining hands-on experience at the intersection of law, business, and technology.

This is an ideal role for someone seriously considering a career in law who is curious, highly organized, a strong writer, and eager to learn in a collaborative environment.

Responsibilities

• Support attorneys with drafting, reviewing, and processing commercial agreements
• Track negotiations, summarize issues, and keep contracts moving to completion
• Partner with internal teams to gather information and support day-to-day legal workflows
• Build, maintain, and improve legal templates, processes, and knowledge resources
• Escalate non-standard or judgment-heavy issues to attorneys as appropriate

Qualifications

• B.A. or B.S. completed
• Excellent attention to detail and strong organizational skills
• Strong writing, communication, and problem-solving ability
• Genuine interest in law, business, and technology
• Ability to manage multiple workstreams and exercise good judgment
• Collaborative, low-ego, team-first mindset

Why This Role

• Rare exposure to cutting-edge AI commercial contracts across IP, data, and research partnerships
• Work directly alongside experienced attorneys in a high-caliber legal environment
• Competitive hourly rate with full-time hours
• Strong resume asset for law school applicants and early-career legal professionals

Note: This position is engaged through a workforce solutions partner and is not a direct employee role. Employment logistics, benefits, and compensation are administered by the staffing partner.