Evolution Vs Evolutionary Biology Jobs in Usa

The Senior Scientist will play a key role in the development, optimization, transfer, qualification, monitoring, and execution of molecular analytical methods supporting gene therapy process development and/or Manufacturing. If you are looking to be part of a highly technical environment with opportunities for growth and new challenges, this role may be the perfect fit for you!

Responsibilities:

• Lead and execute molecular method development, optimization, transfer, qualification, monitoring, and lifecycle management to support gene therapy process development/manufacturing and transfer to GMP testing.
• Design, perform, and interpret complex experiments with minimal supervision to evaluate vector genomes and related molecular attributes using nucleic acid–based technologies (qPCR, dPCR, ddPCR).
• Provide robust in-process analytics and product characterization support for analytical assays that support Process Development and/or Manufacturing, including support of investigations and technical troubleshooting.
• Present data and project updates at cross-functional meetings and contribute to scientific discussions and decision-making.
• Support analytical method qualification activities, continuous improvement initiatives, and data review processes to ensure scientific rigor and regulatory alignment.
• Work with molecular assays as a primary responsibility and, as needed, support analytical testing across additional assay platforms

Education/ Qualifications:

• Bachelor’s or Master’s degree in Molecular Biology, Biochemistry, Cell Biology, Immunology, or related discipline with 6–10 years of relevant industry experience, or a PhD with 3–5 years of industry experience preferred.
• Demonstrated experience in development, optimization, transfer, and execution of molecular analytical methods, particularly PCR-based assays (qPCR, dPCR/ddPCR) for nucleic acid quantification and characterization.
• Experience supporting gene therapy programs, including molecular assays for vector genome titer, residual DNA analysis, and other nucleic acid–based characterization methods.
• Strong expertise in assay troubleshooting, experimental design, and data analysis to support process development, method qualification, and product characterization

Ray Therapeutics mission is to restore vision to people with retinal degenerations. RayTx is using a novel bioengineered optogenetic protein optimized for human vision delivered by AAV to restore visual function in a mutation agnostic approach and without the need for light enhancing eyewear. The company is developing its lead candidate RTx-015 in retinitis pigmentosa, a degenerative retinal disease with significant unmet medical need as well as a pipeline to treat both rare and large market indications.

We are currently seeking an exceptional team member to join our team as a CMC Technical Development Specialist. This role will report to the Senior Director, CMC Analytics, and will have an active role supporting the general CMC department as well as our process, product management, and MSAT teams. The position requires hands on support for AAV analytical development, transfer, and qualification through validation support for our lead candidates from Pre-IND to BLA. The role is based in the Berkeley, CA office with a hybrid work from home/in office requirement and may require travel to our external vendors at in the United States. If the lab is where your curiosity comes alive and breakthroughs spark your excitement, this position may be right for you.

The job duties and responsibilities include but is not limited to the following:

• Collaborate with analytical development and process development teams to develop, qualify and/or validate AAV gene therapy assays.
• Develop analytical methods and support method optimization/characterization.
• Independently execute analytical assays including molecular biology assays, chemical/biochemical assays, and cell-based biological potency assays, for internal CMC commitments, process monitoring, release and stability.
• Develop protocols for analytical transfer, qualification and /or validation studies and execute associated wetlab work.
• Present aasay methodology and principles to external partners and support method transfers.
• Execute routine assays with high presicion and provide data summaries and reports in a timely manner.
• Document all raw data, method plans, and summarize conclusions.
• Author and review Test Methods, Reports, and Protocols.
• Work in the lab independently and in a collaborative environment with minimal guidance.
• Support CMC outside of analytical teams to move programs forward, e.g. shelf-life determination, upstream characterization etc.

Qualifications and Experience:

• BA/BS in Biochemistry, Biology, bioengineering or a related fields and at least 10 years of Biotech/pharmaceutical industry experienced required.
• Experienced in compendial methods, CE-SDS, gel electrophoresis, HPLC, DLS, ddPCR or qPCR, ELISA, and cell based potency assays.
• Hands on experience in AAV gene therapy analytical methods and testing required.
• Experience in precision pipetting and cell culture (handling, aseptic techniques, maintenance), plate-based imaging, ELISAs, luminescence and fluorescence detection techniques.
• Curiosity and good scientific knowledge and acumen.

Compensation Range and Benefits:

• For this role, the anticipated base salary range: $145,000 to $160,000, based on the candidate's professional experience level. The final salary offered for this position may take into account a number of factors including, but not limited to skills, education, and experience.
• Ray Therapeutics also offers annual performance-based bonus, annual equity awards and a comprehensive benefits package.

At Ray Therapeutics, we celebrate diversity and are committed to creating an inclusive environment for all employees; providing an environment of mutual respect where equal employment opportunities are available to all applicants and teammates without regard to race, color, religion, sex, pregnancy, national origin, age, physical and mental disability, marital status, sexual orientation, gender identity, gender expression, genetic information, military and veteran status, and any other characteristic protected by applicable law.

All employment is decided on the basis of qualifications, merit, and business need.

Search Firm Representatives Please Read Carefully

Ray Therapeutics does not accept unsolicited assistance from search firms for employment opportunities. All CVs / resumes submitted by search firms to any employee at our company without a valid written search agreement in place for this position will be deemed the sole property of our company. No fee will be paid in the event a candidate is hired by our company as a result of an agency referral where no pre-existing agreement is in place. Please, no phone calls or emails.

Immediate need for a talented Scientist I. This is a 06+ Months Contract opportunity with long-term potential and is located in Waltham, MA (Onsite). Please review the job description below and contact me ASAP if you are interested.

Job ID:26-08585

Pay Range: $50 - $56/hour. Employee benefits include, but are not limited to, health insurance (medical, dental, vision), 401(k) plan, and paid sick leave (depending on work location).

Key Responsibilities:

• The successful candidate will participate in the development and validation of analytical methods involving cell-based assays, PCR-based assays, and other analytical techniques routinely used to support gene therapy development.
• A strong bioassay background is desired, with a minimum of 2-4 years’ experience in an industry setting performing cell-based assays.
• Molecular biology experience is also a benefit.
• This individual will conduct pre-clinical and clinical lot release and stability testing of viral and non-viral gene therapies.
• This role operates within a cGMP environment and requires excellent verbal and written communication skills, strong attention to detail, and the ability to collaborate effectively with cross-functional departments.
• We are an innovative global healthcare company with one purpose: to chase the miracles of science to improve people’s lives.
• We’re also a company where you can flourish and grow your career, with countless opportunities to explore, make connections with people, and stretch the limits of what you thought was possible. Ready to get started?

Key Requirements and Technology Experience:

• Must Have Skills- Hands-on cell-based assay experience Molecular biology expertise, including PCR Assay development experience
• Nice-to-Have Skills ELISA experience (Enzyme-Linked Immunosorbent Assay) Electronic Lab Notebook (ELN) familiarity Experience working in GxP environments Tools / Platforms ELN ELISA JMP or GraphPad Prism
• Education & Experience Bachelor’s degree + 2–4 years of relevant industry experience Master’s degree + ~2 years of relevant experience PhD not required, but candidates with a PhD will be considered
• Works well independently while possessing strong leadership & communication skills and a demonstrated history of building collaborative, lasting relationships that deliver business results
• Ability to work well in a fast-paced environment and handle multiple priorities successfully
• Ability to work closely with cross functional and other internal teams
• High level of energy, drive, enthusiasm, and commitment with a strong bias for action and prioritization
• Outstanding verbal and written communication skills, as well as demonstrated ability to work confidently and respectfully at all levels of an organization, both internally and externally
• Someone who is highly creative with the ability to think out of the box
• Comfortable working with numbers, metrics & spreadsheets
• Able to influence key partners with ideas that build value.

Our client is a leading Healthcare Industry and we are currently interviewing to fill this and other similar contract positions. If you are interested in this position, please apply online for immediate consideration.

Pyramid Consulting, Inc. provides equal employment opportunities to all employees and applicants for employment and prohibits discrimination and harassment of any type without regard to race, color, religion, age, sex, national origin, disability status, genetics, protected veteran status, sexual orientation, gender identity or expression, or any other characteristic protected by federal, state or local laws.

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Location: San Diego, CA 

Seniority Level: Research Associate (RA) / Senior Research Associate (Sr. RA) 

Employment Type: Full-time 

About OliX Pharmaceuticals 

OliX Pharmaceuticals is a clinical-stage biotechnology company developing next-generation RNA interference (RNAi) therapeutics. Our proprietary asymmetric siRNA (asiRNA) platform enables precise, durable gene silencing and supports delivery platforms such as GalNAc-asiRNA for liver-targeted therapies and cp-asiRNA for local delivery (skin, eye, lung). Active clinical programs and global partnerships (including Eli Lilly, L’Oréal, and Hansoh Pharmaceutical) provide a strong foundation for discovery and development. By joining OliX, you’ll help shape the next generation of RNA medicines. 

Role Summary 

We are seeking a hands-on Research Associate / Senior Research Associate to support the synthesis, deprotection, purification, and analysis of chemically modified oligonucleotides that enable OliX’s RNAi pipeline. You will operate and maintain key instrumentation (e.g., HPLC/UHPLC, preparative LC, TFF, UV–Vis), document work in SOPs, batch records, and reports, and collaborate closely with RNAi chemistry, medicinal chemistry, and biology teams to advance discovery and preclinical programs. 

Key Responsibilities 

• Execute (or Help) solid-phase oligonucleotide synthesis (SPS) and downstream processing (cleavage, deprotection, desalting). 
• Purify and polish oligonucleotides using OPC, analytical and preparative HPLC/UHPLC, and UPLC; perform buffer exchange and concentration via TFF. 
• Develop and optimize purification methods and in-process controls to improve yield, purity, and throughput. 
• Perform analytical characterization (UHPLC/LC–MS, UV–Vis); compile CoAs, batch records, and data summaries. 
• Operate, maintain, and troubleshoot lab instruments; coordinate vendor service when needed. 
• Author and revise SOPs, work instructions, and technical reports; ensure data integrity and traceability. 
• Work cross-functionally with medicinal chemistry and biology teams to align materials specifications and timelines. 
• Maintain safe, compliant laboratory operations and good housekeeping (5S); participate in EHS initiatives. 
• (Sr. RA) Mentor junior team members; lead small method-development or process-improvement projects. 

Qualifications 

Required (RA): 

• B.S. in Chemistry, Biochemistry, Chemical Engineering, or related field with 0–3+ years of relevant lab experience (industry or academic core facility). 
• Hands-on experience with oligonucleotide purification (e.g., OPC, HPLC/UHPLC, preparative HPLC in anion exchange and reverse phase chromatography) and basic analytical techniques (UV–Vis, KF, etc). 
• Familiarity with solid-phase synthesis of workflows and routine instrument maintenance. 
• Strong record-keeping and communication; proven ability to meet deadlines and work effectively in a team. 

Required (Sr. RA): 

• B.S./M.S. in a related field with 3–6+ years of relevant industry experience in oligonucleotide synthesis/purification. 
• Demonstrated proficiency in method development/optimization for oligo purification and in-process analytics. 
• Experience drafting SOPs/batch records and mentoring junior staff. 

Preferred (both levels): 

• Experience with LC–MS data acquisition/interpretation for oligonucleotides. 
• Exposure to nucleoside/nucleotide building blocks or bioconjugation workflows supporting RNAi platforms. 
• Familiarity with TFF operations and scale-up considerations. 

Why Join OliX 

• Contribute directly to an innovative RNAi pipeline with active clinical programs and world-class partnerships. 
• Collaborative, growth-focused environment with cross-functional exposure. 
• Competitive compensation and benefits package (medical, dental, vision, 401(k), equity eligibility, paid holidays/year-end shutdown, stock options). 
• Base salary range of $60,000 – $90,000 (depending on experience and qualifications) 

Work Environment 

• Onsite laboratory role with routine handling of chemicals and analytical instrumentation. 
• Some lifting (up to ~50 lb) and extended periods at the bench or operating instrumentation. 
• Occasional off-hours support during critical runs. 

OliX Pharmaceuticals is an equal opportunity employer. We celebrate diversity and are committed to creating an inclusive environment for all employees. 

Our large pharmaceutical client in Spring House, PA is seeking a passionate and talented lab-based Scientist to support the Immuno-Oncology (I-O) portfolio within the R&D organization. This position will be responsible for driving forward scientific research programs with novel assay implementation, generating translational data, and interrogating Immuno-Oncology assets in a dynamic research lab environment. The candidate will participate in a highly collaborative and interactive team atmosphere while executing experimental approaches to support preclinical biology and clinical assets. Primary responsibilities (include, but are not limited to):

• Design, perform, and interpret complex in vitro, ex vivo, and in vivo experiments
• Isolation and culture of primary cells from blood and tissue
• Execute multi-parameter flow cytometry (FACS) assays end-to-end including set-up and running of samples on the instrument & downstream analysis
• Design, develop, and perform robust in vitro cell assays that incorporate functional readouts, including activation, proliferation, cytokine production, and cytotoxicity
• Analyze and present data in professional 'publication ready' format
• Work independently and manage multiple experiments simultaneously
• Contribute to various projects outside of his/her own and collaborate with stakeholders from all relevant functions

Qualifications:

• Bachelor's or Master's Degree in Biology or related field of study
• 2+ years of tissue cell culture work experience
• Hands-on experience executing multicolor flow cytometry and western blot
• Background in oncology and/or immunology is strongly preferred

Salary: $78,000-$98,000 (flexible based on experience)

Hours: Monday-Friday, 8:00am-5:00pm

Hiring Method: 6 month-long contract with a high likelihood of extensions

PTO: 8 PTO Days & Paid Holidays

Benefits: Medical, Dental, Vision and 401K plans available

Exact compensation may vary based on several factors, including skills, experience, and education. Benefit packages for this role will start on the 31st day of employment and include medical, dental, and vision insurance, as well as HSA, FSA, and DCFSA account options, and 401k retirement account access with employer matching. Employees in this role are also entitled to paid sick leave and/or other paid time off as provided by applicable law.

100% ONSITE

Pay: $48-$52/hr

REQUIRED:

• Minimum: Master’s degree + 2‑5 years relevant experience
• Bachelor’s acceptable with 5 years strong hands‑on background
• Background in microbiology, immunology, cell/molecular biology, or biotech
• Hands‑on experience with NGS (Illumina MiSeq/iSeq) – must‑have
• Microfluidics: emulsion, droplet generation, custom or commercial systems
• B‑cell purification and handling
• Molecular biology: polymerase reactions, RNA/DNA purification, indexing
• Basic data analysis; familiarity with commercial sequencing software
• Scripting in Python or R for data processing (plus)
• Bioinformatics tools (IMGT, IgBLAST)
• Protein detection methods (ELISA, similar assays)
• Experience with other NGS platforms (Thermo Fisher, PacBio, ONT) – nice to have

Job Description:

B-Cell Sequencing is the focus of this group - downstream (Extracting antibodies from individual B cells and sequencing them to find new drug candidates)

The successful candidate will support the development of new paired antibody sequencing technologies from single B cells using droplet microfluidics. Responsibilities include experimental planning and execution, comprehensive B cells sequencing analysis and presentation, and detailed documentation to support multiple programs across our in vivo antibody discovery portfolio.

Responsibilities

- Experimental Design & Execution: Independently design, execute and interpret experiments utilizing microfluidics to amplify heavy and light chain genes and generate DNA libraries for deep sequencing of single B cells captured in droplet emulsions.

- Understand the broad objectives of the project as well as their role in achieving those objectives, and modify the experimental plan when required. Set and meet experimental timelines.

- Molecular Techniques: Demonstrate a high level of proficiency in conducting RNA isolation, and DNA purification, and related methods to amplify antibody heavy- and light-chain variable regions from single cells or lysates and submit DNA libraries for next generation sequencing (MiSeq/MiSeq i100).

- Bioinformatics Data Analysis: Perform comprehensive in silico antibody genetic analysis and data visualization using standard and custom antibody bioinformatic tools – to guide program decisions and deliver biotherapeutic candidates.

- Cross-Functional Collaboration: Collaborate with multidisciplinary teams to present/discuss experimental findings to ensure alignment with overall biotherapeutic development goals.

- Ability to work independently and as part of a team, managing multiple projects simultaneously.

Location: Wichita, KS

Facility: Ascension Via Christi St Joseph 

Department: Adult Psychiatry Nursing Unit

Schedule: Night-Shift | Full-Time

Sign on Bonus:  Up to $10,000

Via Christi associates are eligible for tuition discounts and priority placement in select healthcare programs through our academic partnership with Wichita State University.

Ascension is a leading nonprofit Catholic health system with a culture and associate experience grounded in service, growth, care and connection. We empower our 99,000+ associates to bring their skills and expertise every day to reimagining healthcare, together. Recognized as one of the Best 150+ Places to Work in Healthcare and a Military-Friendly Gold Employer, you’ll find an inclusive and supportive environment where your contributions truly matter.

• Comprehensive health coverage: medical, dental, vision, prescription coverage and HSA/FSA options
• Financial security & retirement: employer-matched 403(b), planning and hardship resources, disability and life insurance
• Time to recharge: pro-rated paid time off (PTO) and holidays
• Career growth: Ascension-paid tuition (Vocare), reimbursement, ongoing professional development and online learning
• Emotional well-being: Employee Assistance Program, counseling and peer support, spiritual care and stress management resources
• Family support: parental leave, adoption assistance and family benefits
• Other benefits: optional legal and pet insurance, transportation savings and more

Benefit options and eligibility vary by position, scheduled hours and location. Benefits are subject to change at any time. Your recruiter will provide the most up-to-date details during the hiring process.

• Direct holistic patient recovery by performing comprehensive bio-psychosocial assessments that capture the full picture of a patient's physical and mental well-being.
• Design individualized care pathways by developing and evolving nursing plans that align with the broader treatment team’s goals to ensure every patient has a clear road to stability.
• Facilitate therapeutic breakthroughs by leading group therapy sessions and implementing evidence-based interventions that empower patients to develop healthy coping mechanisms.
• Advocate as a clinical expert within multidisciplinary team conferences, ensuring that nursing insights directly influence the evolution of the patient’s treatment and safety.
• Monitor and pivot care strategies by continuously evaluating patient responses to treatment, allowing for real-time adjustments that reflect the patient’s current status and needs.

Licensure / Certification / Registration:

• BLS Provider obtained within 1 Month (30 days) of hire date or job transfer date required.  American Heart Association or American Red Cross accepted.
• Licensed Registered Nurse credentialed from the Kansas Board of Nursing required.

Education:

• Diploma from an accredited school/college of nursing OR professional licensure at time of hire required.

Equal employment opportunity employer

Ascension provides Equal Employment Opportunities (EEO) to all associates and applicants for employment without regard to race, color, religion, sex/gender, sexual orientation, gender identity or expression, pregnancy, childbirth, and related medical conditions, lactation, breastfeeding, national origin, citizenship, age, disability, genetic information, veteran status, marital status, all as defined by applicable law, and any other legally protected status or characteristic in accordance with applicable federal, state and local laws. For further information, view the EEO Know Your Rights (English) poster or EEO Know Your Rights (Spanish) poster.

Fraud prevention notice

Prospective applicants should be vigilant against fraudulent job offers and interview requests. Scammers may use sophisticated tactics to impersonate Ascension employees. To ensure your safety, please remember: Ascension will never ask for payment or to provide banking or financial information as part of the job application or hiring process. Our legitimate email communications will always come from an @ email address; do not trust other domains, and an official offer will only be extended to candidates who have completed a job application through our authorized applicant tracking system.

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Employer participates in the Electronic Employment Verification Program. Please click here for more information.

Summary:

Performs all lab assistant procedures (including, but not limited to, phlebotomy, client processing, and client services representative functions) and oversees such staff under the guidelines and supervision of the assigned Leader to assure appropriate patient care is met. Responsible for monitoring, rotating stock, or requesting general laboratory and phlebotomy supplies as needed. Assists in specimen processing/handling, collection, and designated testing functions in all areas of the lab.

Responsibilities:

• Meets expectations of the applicable OneCHRISTUS Competencies: Leader of Self, Leader of Others, or Leader of Leaders.
• Customer Service / AIDET / Standards of Behavior.
• Trains and performs competency checklist with all Phlebotomist/ laboratory assistant staff.
• Monitors the collection report;
  resolves problems;
  completes related paperwork and computer functions.
• Uses centrifuge, prepares and assures serum/blood specimens are acceptable;
  prepares specimen for referral to outside reference laboratories;
  dispenses blood products under supervision of medical technologist.
• Monitoring the collection area continuously during the shift to assure that all specimens are collected within a timely manner and assisting the phlebotomists in obtaining specimens, if necessary.
• Handling inquiries, questions and problems as they arise, both within the laboratory and between the lab and other departments in the hospital, maintaining a professional image and exhibiting excellent service. Greets all customers, clients, outpatients, and visitors physically or on the telephone;
  provides accurate, appropriate, and courteous response to technical questions and results inquiry as requested by physicians and nursing personnel.
• Communicating follow-up information regarding patient care issues or physician related complaints to the appropriate supervisor, manager, charge tech or director.
• Performs clerical office duties, client processing, and client service representative duties, as assigned/required.
• Enters orders and cancellations using Hospital LIS. Receives and processes specimens collected and/or add-on tests and distributes them to the appropriate departments.
• Processes and maintains laboratory records and reports;
  monitors chart print rounds for completion and processes reports for Health Information, faxes or mails reports as requested by physicians or clients, processes reference reports, resolves all pending transactions, and maintains printers, copier, and fax machine.
• Specimen collections are initiated within the appropriate response time. Monitors the collections pending. Reports and resolves problems, completes related paperwork and computer functions.
• Works as a team member to perform and complete all patient related testing/reporting regardless of individual assignments, to provide timely results on a daily basis. Completes tasks or special projects within the time frame, allowed per any guidelines established as assigned by laboratory supervisory personnel.
• Inventory control – monitors supply receiving area, distributes supplies, restocks, and processes packing slips;
  notifies appropriate supervisor/manager when instrument parts, reagents, or supplies are at reorder levels;
  dates reagents when received and opened according to laboratory policy, and notifies supervisor of expired reagents;
  completes supply orders, as assigned.
• Practices safety, infection control, and security as defined by the hospital department and section policy and procedure manuals;
  follows all safety and infection control procedures including wearing appropriate PPE for assigned job functions;
  disposes of biohazardous materials and hazardous chemicals as established by departmental policy;
  all patient information, including lab results, are maintained in the strictest of confidence, limited to health care professionals needing this information to perform patient care.
• Demonstrates work schedule flexibility by willingly rotating shifts and changing assignments, as required.

Job Requirements:

Education/Skills

• Associate of Science Degree preferred
• Basic knowledge in the areas of microbiology, immunology or molecular biology and biochemistry as related to infectious diseases required

Experience

• 2 years of experience as a Phlebotomist or Laboratory Assistant in a clinical laboratory setting required
• 5+ years of experience preferred

Licenses, Registrations, or Certifications

• Medical Laboratory Assistant Certification or Phlebotomist Certification - PBT (ASCP), RPT (AMT), CPT (NPA) or equivalent required
• Louisiana requires State Licensure

In accordance with the CHRISTUS Health License, Certification and Registration Verification Policy, all Associates are required to obtain the required certifications for their respective positions within the designated time frame.

Work Schedule:

MULTIPLE SHIFTS AVAILABLE

Work Type:

Full Time