Engineering Jobs in Pacifica California
157 positions found — Page 5
Tool Room Manager – Medical Device Manufacturing (Bay Area, CA)
I’m supporting a leading medical device organization that is looking for a hands-on Tool Room Supervisor to lead the maintenance, repair, and optimization of 300+ complex injection molds — including hot runners, PEEK, and glass-filled materials.
This is a high-impact role overseeing a tool room team while driving mold performance, uptime, and continuous improvement across a fast-paced manufacturing environment.
What’s Offered:
• Competitive salary: $130K
• Relocation sign-on bonus for non–Bay Area candidates
• Medical, dental & vision (effective day 1)
• Company-paid life insurance & disability
• 401k with company match
• Generous PTO + 10 paid holidays
• Tuition reimbursement
• Additional perks: legal plan, pet insurance & home ownership program
If you have strong experience in injection mold repair, tooling, EDM, TIG welding, hot runners, or tool room leadership, I’d love to connect.
Interested? Send me your resume or best contact information or resume.
#injectionmolding #tooling #manufacturing #medicaldevices #hiring #toolroom #moldmaking #engineering #bayareajobs
ProcureAbility, a Jabil company, is the leading procurement services company, offering advisory, managed services, digital, staffing, and recruiting solutions. For 30 years, we have focused exclusively on helping clients elevate their procurement function. We combine leading methodologies, analytics, market intelligence, and industry benchmarks with our uniquely flexible and customizable service delivery model. Global organizations of all sizes trust ProcureAbility to transform their procurement operations, drive growth, and reimagine what’s possible.
Job Title: Sourcing and Contract Specialist
Our client, a leader in their industry, is hiring Sourcing and Contract Specialists. These are contract roles, currently scheduled through 12/31/26 with potential to convert to direct hire.
Hybrid Role: Training will be on-site for 2 weeks, and then the role will be hybrid. After the training period, the work is expected to be mainly remote with occasional on-site meetings.
Location: East San Francisco Bay area
Job Category: Procurement / Supply Chain
Job Level: Individual Contributor
Applicants must be authorized to work for ANY employer in the U.S. ProcureAbility is unable to sponsor or take over sponsorship of an employment Visa at this time.
What can you expect to do?
Responsibilities:
• Conducts negotiations with bidders, for non-routine, may support or work with Sourcing.
• Coordinates and assembles supporting documentation to support audits.
• Works with vendors and internal stakeholders to assemble, review, prepare, and route for vendor and management approval (using ARIBA and EDRS), necessary documents for these tasks.
• Works with vendors, Project Team to improve quality of supporting contract documents to reduce rework required by others.
• May assist in the creation and development of purchase requisitions.
• For Routine Contracts, reviews vendor proposals to ensure that rates and terms are consistent with outline agreements.
• May support / review vendor proposals to ensure that rates and terms are consistent with outline agreements.
• Ensures that Company standards are followed when executing contract documents.
• Tracks approval status of contracting documents from inception through approval and ensures that documents are routed expeditiously.
• For Routine Contracts, conducts negotiations with bidders, for non-routine, may support or work with Sourcing department.
• Reviews purchase orders and contracts as part of procurement approval process.
• Provides technical support and analysis in preparation of scope, cost, schedule, safety and environmental concerns pertinent to the contract specifications; and verify and process contract invoices.
What is needed to be successful in this role?
• Bachelor’s Degree in Construction Management, Engineering, Business Administration or related field
• Ability to work in cross-functional teams
• Ability to work in a team environment
• Ability to work on multiple issues and tasks
• Advanced in MS Excel, PowerPoint
• Demonstrated competencies on use of supply chain management tool (e.g. ARIBA) and other business systems tools (SAP, SharePoint, EDRS)
• Demonstrated knowledge of Company standards regarding contracting processes.
• Conflict resolution/negotiation skills
• Demonstrated ability to track contract costs, purchase order status, and other required information in SAP
• Demonstrated competencies on use of ARIBA and EDRS is a plus
• Process improvement experience
• Presentation Skills
• Verbal and Written Communication Skills
• Knowledge of Contractual Terms and Conditions
ProcureAbility, A Jabil Company, is proud to be an Equal Employment Opportunity and Affirmative Action Employer. We do not discriminate based on race, religion, color, national origin, gender, sexual orientation, gender identity, gender expression, age, status as a protected veteran, status as a person with a disability, or other legally protected characteristics.
If you are a Qualified Person with a Disability or a Disabled Veteran and require assistance making your application, please get in touch with HR at
Don’t meet every single requirement? Studies have shown that women and people of color are less likely to apply for jobs unless they meet every qualification. At ProcureAbility, we are dedicated to building a diverse, inclusive, and authentic workplace, so if you’re excited about this role but your experience doesn’t align perfectly with every qualification in the job description, we encourage you to apply anyway. You may be just the right candidate for this or other roles.
Technical Designer, Furniture
SAUSALITO, CA
Serena & Lily is seeking a Technical Furniture Designer to join our Design Team. The ideal candidate will be responsible for the technical development process of all furniture categories. This role involves ensuring that quality, accuracy and on time execution in a cost-effective manner of all furniture projects from concept to production, are met while maintaining brand integrity. This position reports directly to CDO.
RESPONSIBILITIES:
- Translate design direction from CDO into detailed technical specs with accurate renderings to illustrate concept ideals.
- Develop and implement product development strategies aligned with company goals and market trends.
- Identify opportunities for innovation in furniture production, materials, and production processes.
Project Management
- Translate design direction from CDO into detailed technical specs with accurate renderings to illustrate concept ideals.
- Oversee the product development lifecycle, from initial renderings to cads, to sample and swatch reviews.
- Clearly communicate to agents and vendors calls outs and comments in a timely manner.
- Develop new finishes and color panels and ensure consistency through production.
- Ensure projects are delivered on time, within budget, and meet quality standards.
- Own the sharing of information in weekly PD meetings.
- Keep all documents and shared tools current and up to date.
- Maintain and organize swatch libraries.
- Cad all cushions where applicable and all outdoor covers for outdoor collections.
- Confirm PI sheets are accurate.
- Review and comment on furniture renewal swatches in a timely manner.
Quality & Compliance
- Establish and maintain quality assurance protocols throughout the product development process.
- Ensure all products meet regulatory and safety standards for target markets.
- Address and resolve product issues promptly and effectively.
Key Personal Attributes
- Strategic thinking and ability to align product development with business goals.
- Strong problem-solving skills and adaptability in a dynamic environment.
- Attention to detail and commitment to quality.
- Collaborative mindset with the ability to develop strong cross functional and respectful relationships.
- Strong work ethic with an ability to turn on a dime.
- Be part of a small tight knit team with a desire to jump in where needed to assist in department projects.
QUALIFICATIONS:
- Bachelor’s degree in industrial design, Product Development, Engineering, or related field.
- 5+ years of experience in furniture product development.
- Strong knowledge of furniture design, materials, manufacturing processes, and industry standards.
- Proven track record of managing multiple complex product development projects.
- Excellent leadership, communication, and interpersonal skills.
- A high level of proficiency in design software (e.g., AutoCAD, SolidWorks) and project management tools.
- Experience with sustainability practices in furniture design is a plus.
COMPENSATION:
- $100-130k per year is the anticipated starting base pay for this role. This range represents the low and high end of the anticipated base salary range for this role. The actual base pay is dependent upon many factors, such as: experience, education, and skills.
- Employees (and their families) are covered by medical, dental, vision, and basic life insurance should they choose to participate in Serena & Lily’s benefits. Employees can enroll in our company’s 401k plan. During the first year of employment, full-time employees accrue twenty-one days of PTO and seven paid holidays throughout the year.
Manufacturing Technician - Machine Assembly & Test
Contract
Fremont, CA (Onsite)
This position pays around $28/hr - $32/hr on W2
Job Summary
The Manufacturing Technician will be responsible for the hands-on assembly, testing, and troubleshooting of their production systems. This role will involve working closely with engineers and other technicians to ensure the quality and performance of our machines. The ideal candidate possesses a strong mechanical aptitude, experience with assembly and testing processes, and a commitment to quality and safety.
Responsibilities
- Assemble complex mechanical and electromechanical systems according to work instructions and engineering drawings.
- Perform functional testing of assembled systems, including data collection and analysis.
- Troubleshoot and diagnose mechanical and electrical issues.
- Use hand tools, power tools, and precision measuring instruments to assemble and test equipment.
- Read and interpret schematics, wiring diagrams, and assembly drawings.
- Follow standard operating procedures (SOPs) and safety guidelines.
- Maintain a clean and organized work area.
- Collaborate with engineers and other technicians to improve assembly and test processes.
- Document assembly and test results accurately.
- Identify and report any quality issues or discrepancies.
- Assist with the installation and commissioning of new equipment.
- Contribute to a positive and collaborative team environment.
Qualifications
- High school diploma or equivalent; technical certification or associate's degree in a related field is a plus.
- 2+ years of relevant experience in manufacturing or a related field, preferably with experience in machine assembly and testing.
- Strong mechanical aptitude and hands-on skills.
- Experience with using hand tools, power tools, and precision measuring instruments (e.g., calipers, micrometers).
- Ability to read and interpret schematics, wiring diagrams, and assembly drawings.
- Familiarity with basic electrical and mechanical principles.
- Excellent problem-solving and troubleshooting skills.
- Ability to work independently and as part of a team.
- Strong attention to detail and commitment to quality.
- Good communication and interpersonal skills.
- Experience with data collection and analysis is a plus.
Senior Manufacturing Process Engineer
Meet has partnered with an exciting Stealth start-up in the Brain-Computer Interface (BCI) space based in the San Francisco Bay area. The company is developing cutting-edge medical devices and technology for the treatment of unmet neurological disorders. The Head of Operations is seeking an experienced Manufacturing Process Engineer to support NPI of electro-mechanical devices in collaboration with suppliers.
This role will focus on hands-on interaction with suppliers to develop manufacturing processes, tooling, and documentation, from design feasability through commercial release. This role will require real-time engagement and technical support of suppliers, and this individual will be expected to travel often to domestic supplier sites and occasionally to international suppliers.
Primary Responsibilities:
- Serve as the primary technical liaison to external manufacturing partners, ensuring successful delivery of components, assemblies, and finished devices
- Collaborate with product development teams to ensure designs are manufacturable and compliant with medical device quality system requirements
- Develop and maintain manufacturing documentation, including work instructions, process flows, and validation protocols
- Support supplier implementation of specifications, manufacturing processes, and quality requirements
- Lead and participate in process validation activities including IQ/OQ/PQ, PFMEA, and failure investigations
- Drive continuous improvement initiatives related to manufacturing efficiency, quality, cost, and scalability
- Support resolution of non-conformances and corrective actions with suppliers
- Ensure manufacturing activities comply with applicable regulatory requirements (FDA, ISO 13485, EU MDR, etc.)
- Provide hands-on technical support to suppliers, including travel as needed (domestic and international)
Role Requirements:
- B.S. in relevant engineering discipline, or equivalent experience.
- 10 or more years of medical device manufacturing experience, preferably in senior roles at start-up companies developing and manufacturing electro-mechanical devices.
- Experience with active implantable systems (Implant, Leads, Externals, etc.).
- Experience with medical device manufacturing including molding, laser welding, clean room assembly, packaging, labeling, and sterilization.
- Experience with electronic manufacturing and test including PCB fab, PCA assembly, microelectronics assembly, flip chip, in circuit test (ICT) and functional test.
- Experience with manufacturing automation.
- Experience in defining and executing process validation activities.
- Experience collaborating with internal customers and external partners.
- Understanding of and experience implementing validating manufacturing processes for medical devices in accordance with FDA and EU Requirements.
- Experience with Solidworks, Labview / manufacturing process and test automation software.
- Ability to travel to Domestic and International supplier sites frequently
Head of Operations and Manufacturing Ripple Medical | California (Hybrid or Remote) | Full-Time
ABOUT RIPPLE MEDICAL
Ripple Medical is a health tech company on a mission to revolutionize hypertension management with our cuffless blood pressure wearable. Once cleared by FDA, our product will enable patients to easily and accurately monitor blood pressure at home, empowering them and their providers with actionable data to improve outcomes. We're a collaborative, mission-driven team of 33 working in a medical device regulatory environment to bring this technology to the millions of patients who can benefit.
POSITION SUMMARY
The Head of Operations and Manufacturing will own the end-to-end operational infrastructure required to bring Ripple's FDA-regulated cuffless blood pressure monitor to market and scale production. This is a hands-on leadership role for someone who thrives building from zero to one in a regulated environment: selecting contract manufacturers, standing up supply chains compliant with FDA 21 CFR Part 820, establishing ISO 13485-certified quality management systems, and preparing for direct-to-patient fulfillment.
As a company preparing for 510(k) submission and commercial launch, this role is critical to ensuring we can reliably manufacture and deliver a high-quality, FDA-cleared medical device at scale. The ideal candidate brings deep experience in medical device manufacturing (particularly wearable or electro-optical devices), understands regulated hardware supply chains and design transfer, and can roll up their sleeves while building the team and processes for long-term growth.
This position reports directly to the CEO with high visibility to the leadership team and Board of Directors.
KEY RESPONSIBILITIES
Manufacturing & Production
- Lead selection and onboarding of contract manufacturing partners with Class II medical device experience, including RFQ, quality audits, contract negotiation, and ongoing management.
- Own design transfer and manufacturing transfer, working with engineering on DFM principles, Device Master Record (DMR) requirements, and production readiness.
- Establish production planning, forecasting, and capacity management for V&V builds, pilot production, and volume manufacturing.
- Drive continuous improvement in yield, quality, and cost while maintaining FDA and ISO compliance.
- Oversee pilot runs and scale-up, including process validation (IQ/OQ/PQ) and manufacturing controls.
Supply Chain & Procurement
- Build and manage the end-to-end supply chain, including component sourcing, supplier qualification, and inventory management per FDA purchasing controls.
- Develop supplier relationships and negotiate terms while ensuring supply continuity, traceability, and risk mitigation.
- Implement inventory planning to balance working capital with service levels, including buffer strategies for Year 1 launch.
- Monitor and mitigate supply chain risks: component shortages, single-source dependencies, geopolitical factors, and logistics disruptions.
Quality & Regulatory Compliance
- Maintain and improve the ISO 13485-certified QMS in partnership with the quality and regulatory team, ensuring FDA 21 CFR Part 820 compliance.
- Support 510(k) submission activities related to manufacturing, including process validation documentation, DMR development, and device history records (DHR).
- Define incoming inspection, in-process controls, and final product testing consistent with the risk management file.
- Manage product certifications for a Class II device, including FDA registration, UDI compliance, and applicable international requirements.
- Lead root cause analysis and CAPA for quality issues, ensuring post-market surveillance compliance.
Fulfillment & Logistics
- Design the direct-to-patient fulfillment strategy, including 3PL selection with FDA-cleared Class II device experience.
- Establish logistics and distribution for nationwide shipping of a regulated device with chain-of-custody and traceability.
- Develop returns, replacement, and warranty processes that balance patient experience, cost, and compliance.
Team & Organizational Development
- Start as an individual contributor who executes hands-on, then build and lead the operations team through 510(k) clearance and commercial launch.
- Establish operational metrics and dashboards for manufacturing, supply chain, and quality performance.
- Partner with finance on cost modeling, COGS optimization, and operational budgeting.
- Collaborate cross-functionally with engineering, software, regulatory, and commercial teams.
QUALIFICATIONS
- 7-12 years in manufacturing, operations, or supply chain, with 3-5+ years in medical devices (Class II preferred), wearables, or regulated hardware.
- Experience managing contract manufacturers for regulated medical devices, preferably in Asia and/or domestically.
- Experience at or with CMs/EMS providers (Flex, Jabil, Celestica, Plexus, Sanmina) in Class II medical device or wearable programs is a strong plus.
- Track record of design transfer and scaling production from pilot to volume for regulated products.
- ISO 13485 and FDA 21 CFR Part 820 experience required.
- Familiarity with the 510(k) process and manufacturing documentation (process validations, DMR/DHR) strongly preferred.
- Bachelor's in Engineering, Supply Chain, Operations, Biomedical Engineering, or related field; MBA or advanced degree a plus.
- Based in California or travel up to 25%.
COMPENSATION
- Base Salary: $160,000 - $210,000 USD
- Performance Bonus: Tied to company milestones and personal objectives
- Equity: Early-stage stock option grant with meaningful ownership
- 100% Employer-Paid Healthcare: Medical, dental, and vision
- Additional Benefits: 401(k) with company match, flexible PTO
Our client is looking for an IP Litigation Associate with 3 to 5 years of AMLAW 200 experience for their very sophisticated practice group. The firm is looking for those that have backgrounds in Electrical Engineering or Computer Science from top schools for this above market to market salary opportunity in any of their 3 locations: Washington D.C., New York or San Francisco. This is a fantastic opportunity to work with a close-knit group that offers no billable hour requirements and the ability to work on some of the most important intellectual property disputes in recent times. If you or someone you know meet these requirements, please message me today. I would LOVE to chat!
Sequoia Living – San Francisco High-Rise Community
Sequoia Living is seeking an experienced, mission-driven Director of Environmental Services to lead operations in our high-rise community. This is a highly visible leadership role responsible for creating a safe, clean, efficient, and beautifully maintained environment for the residents who call our community home.
If you are a hands-on, solutions oriented facilities professional who thrives in a dynamic environment and you are passionate about leading teams, elevating service standards, and improving the daily lived experience of residents this is a unique opportunity to make a meaningful impact.
Experience in a CCRC, senior living, healthcare, assisted living, or hospital setting is required.
Why This Role Matters
As the Director of Environmental Services, you are the operational backbone of the community. You ensure residents live in a well-maintained, safe, and welcoming environment while leading a diverse and dedicated team across plant operations, maintenance, housekeeping, laundry, landscaping, safety, and construction oversight. Your work directly impacts resident experience, staff satisfaction, regulatory compliance, and long-term asset preservation.
What You’ll Do (Key Responsibilities)
Leadership & Department Oversight
- Lead all Environmental Services functions, including plant operations, maintenance, housekeeping, laundry, landscaping, and safety programs.
- Recruit, hire, mentor, and develop supervisors and frontline staff; foster a culture aligned with Sequoia Living’s Mission, Vision, Values, and Commitment to Inclusion.
- Manage administrative operations, staff schedules, training, coaching, and performance review processes.
Facility Operations & Maintenance
- Oversee the community’s preventative and corrective maintenance programs, ensuring compliance with all Federal, State, and local regulations (EPA, ADA, OSHA/OSHPD, Titles 8, 19, 22 & 24).
- Review maintenance projects, repairs, and inventory needs; recommend improvement plans to community leadership and the Director of Design & Construction.
- Ensure the community’s safety programs (Fire, Disaster, Emergency Response, Hazardous Materials Plans) are up-to-date and fully implemented.
- Train staff in safe work practices, including asbestos and industrial chemical handling.
Construction, Capital Projects & Renovations
- Manage capital project planning and execution, including apartment renovations, building upgrades, and major infrastructure improvements.
- Maintain computerized capital budget tools, plan expenditures, and ensure timely project completion.
- Solicit and evaluate contractor bids; manage vendor relationships, permits, and certificates of insurance.
Budgeting & Resource Management
- Prepare and manage operating and capital budgets; track expenses and ensure cost control.
- Oversee energy conservation and utility monitoring to optimize efficiency.
Resident & Community Engagement
- Serve as a responsive partner to residents and committees on maintenance needs and special projects.
- Communicate professionally and collaboratively with department heads, staff, vendors, regulatory bodies, and Sequoia Living leadership.
Risk, Safety & Compliance
- Act as the community’s Safety Coordinator: oversee workplace safety programs, ensure incident reporting, support workers’ compensation processes, and lead safety initiatives.
- Identify and report resident concerns related to physical, mental, or emotional well-being.
- Participate in on-call rotation and support emergency response as needed.
What You Bring (Qualifications)
Experience
- 6+ years of hands-on experience in environmental services, facilities management, plant operations, or maintenance preferably in healthcare, senior living, or a residential community.
- 3+ years of supervisory or management experience leading diverse teams.
- Prior experience with building systems (HVAC, boilers, refrigeration, electrical/mechanical systems, automation, and life/safety equipment).
- CCRC or healthcare environment experience strongly preferred.
Education
- High school diploma required; 2+ years of college or trade school coursework in engineering, facilities management, or environmental services preferred.
- Bachelor’s degree in Engineering, Facilities Management, or related field strongly preferred.
Key Knowledge & Skills
- Regulatory & Compliance: Deep understanding of building codes, construction regulations, OSHA/OSHPD, Titles 8, 19, 22 & 24, ADA, and environmental compliance.
- Technical Proficiency: Ability to read blueprints, technical manuals, and schematics; strong understanding of HVAC, plumbing, electrical, carpentry, and mechanical systems.
- Safety & Risk Management: Expertise in workplace safety, hazardous materials handling, emergency response, and risk mitigation.
- Operational Excellence: Skilled in housekeeping, maintenance, landscaping, sanitation, and environmental cleaning standards.
- Project Management: Strong planning, scheduling, and vendor management experience.
- Technology Skills: Proficient with Microsoft Office and capable of learning maintenance, inventory, and HR systems.
- Communication & Leadership: Collaborative, calm under pressure, resident-centered, and able to lead with empathy and professionalism.
Why Work at Sequoia Living?
- A mission-driven organization devoted to enriching the lives of older adults.
- An opportunity to lead a critical operations team in an established and respected nonprofit community.
- A collaborative culture where your expertise directly shapes resident safety, comfort, and quality of life.
- A role with variety, challenge, and the ability to influence long-term building health and operational excellence.
Ready to Make an Impact?
If you are a proactive leader who finds purpose in maintaining exceptional environments, developing strong teams, and ensuring operational excellence we encourage you to apply. Join a community that values integrity, compassion, and innovation.
At Two Bear Capital we believe in partnering with our portfolio companies to build the best teams possible. We look forward to working with you and Rainfall Health on their new Director of Software Engineering role.
Director of Software Engineering (AWS Amplify & Digital Health)
*please note that this role requires willingness to travel to the Bay area and/or relocating to the Bay area
*please note that this position requires US citizenship/does not provide sponsorship
About Rainfall Health
Rainfall Health is an AI-powered compliance and workflow platform helping health systems succeed under CMS’s TEAM Model and other value-based care programs. We partner with hospitals, surgeons, and care teams to improve episode performance, streamline operations, and maximize reimbursement — all while supporting better patient outcomes.
Our platform sits at the intersection of clinical workflows, financial performance, and intelligent automation.
The Role
We are looking for a Director of Software Engineering with deep experience in AWS Amplify and modern cloud-native architectures to help build and scale our digital health platform. You’ll play a key role in designing secure, reliable systems that integrate with healthcare data sources and surface actionable insights to clinical and operational teams.
This role is ideal for someone who enjoys solving complex data and workflow challenges in a regulated healthcare environment.
What You’ll Do
Platform & Application Development
- Design, build, and maintain scalable web applications using AWS Amplify, serverless services, and modern frontend frameworks
- Develop robust APIs and backend services using AWS-native tools (e.g., AppSync, Lambda, DynamoDB, RDS)
- Ensure performance, reliability, and security across distributed cloud systems
Healthcare Data & Integrations
- Build and maintain integrations with Electronic Health Records (EHRs) and other healthcare systems
- Work with healthcare interoperability standards such as FHIR, HL7, and APIs from major EHR vendors
- Design data ingestion pipelines that normalize, validate, and securely store clinical and operational data
Data Visualization & Insights
- Develop interactive dashboards and data visualization tools for clinical and operational users
- Translate complex healthcare data into intuitive, actionable insights
- Collaborate with product and design teams to create user experiences tailored to care teams and administrators
Cross-Functional Collaboration
- Work closely with product managers, designers, and clinical stakeholders to deliver features aligned with real-world workflows
- Contribute to architectural decisions and technical roadmap planning
- Mentor other engineers and promote best practices in code quality, testing, and security
Security & Compliance
- Implement best practices for HIPAA-compliant infrastructure and data handling
- Ensure systems meet high standards for privacy, auditability, and reliability in a healthcare environment
What We’re Looking For
Required:
- 8+ years of software engineering experience building production-grade applications
- Hands-on experience with AWS Amplify and serverless AWS architectures
- Strong experience with modern JavaScript/TypeScript frameworks (e.g., React, Next.js, Vue)
- Experience building and consuming RESTful and/or GraphQL APIs
- Solid understanding of cloud security and best practices for handling sensitive data
Preferred:
- Experience in digital health, healthcare IT, or healthtech startups
- Experience integrating with EHR systems (Epic, Cerner, Meditech, etc.)
- Familiarity with FHIR, HL7, CCD, or other healthcare data standards
- Experience building data visualization tools (e.g., D3, Chart.js, Recharts, or BI tools)
- Knowledge of healthcare compliance frameworks (HIPAA, HITRUST, SOC 2)
Nice to Have
- Experience with real-time data pipelines or event-driven architectures
- Background in analytics, population health, or value-based care technology
- DevOps experience with CI/CD pipelines and infrastructure as code
What Success Looks Like
- Seamless, secure integrations with healthcare systems
- Intuitive dashboards that drive decision-making for clinical and operational teams
- A scalable, maintainable architecture that supports rapid product growth
- Strong engineering culture centered on reliability, security, and user impact
Amber Bio is a biotechnology company pioneering new gene editing modalities using multi-kilobase edits to reach previously undruggable patient populations. Founded by pioneers in the CRISPR field from leading institutions for gene editing research, the company is developing a first-of-its-kind RNA editing platform that can correct thousands of bases at once, thereby correcting genetic mutations safely and reversibly. If you are interested in building a new frontier in genetic medicine, we welcome you to apply.
Job Description: High-Throughput Screening Research Associate II, III (Biodesigner II, III)
Responsibilities:
- Perform massively parallel reporter assays and high-throughput screens across diverse cellular contexts using cellular and molecular readouts.
- Develop and execute molecular biology workflows such as vector design and cloning, DNA/RNA extraction, RT-PCR, qPCR, and next-generation sequencing.
- Support cell culture activities and experiments in multiple cell lines, at small and large scales.
- Design and execute cell-based assays (AAV/lentiviral transduction, transfection, flow cytometry, immunostaining, and other plate reader assays).
- Engineer and characterize cell-based systems using synthetic biology tools and techniques.
- Conduct and troubleshoot experiments, independently and in collaboration with colleagues, to optimize screening throughput, sensitivity, and specificity.
- Proactively troubleshoot technical issues and recommend potential corrective actions based on personal observations and literature searches.
- Prepare summaries of data and present internally to colleagues and management.
- Draft SOPs, follow protocols, diligently document experimental data in lab notebooks, and organize and maintain electronic work records.
- Author scientific reports and data summaries.
- Collaborate with cross-functional teams to meet project goals, bridging early discovery with high-throughput screens to nominate and optimize candidates for further characterization.
Qualifications:
- Bachelor’s or Master’s degree in Biology, Biochemistry, Chemical Engineering, Biological Engineering, or a related field.
- At least 2 years of industry wet lab experience.
- Mammalian cell culture experience (culturing, transfecting and transducing cells, and DNA/RNA purification from cells).
- Molecular biology expertise (vector design and cloning, qPCR, primer and probe design, DNA/RNA extraction workflows)
- Critical thinker with excellent communication skills who thrives in a multidisciplinary, fast-paced team environment.
- Strong written and verbal communication skills.
Preference will be given to those who display:
- High throughput screening assay development in an industry setting.
- High motivation, with a strong work ethic and dedication to generating impact.
- Attention to detail, with the ability to extract deep insights from data.
- First-principles thinking, and an ability to refine one’s intuition based on additional data.
- Ability to go from ideation to data in an independent fashion.
- Long-term personal vision with defined career goals.
- High EQ with team-oriented thinking.
- Experience with pooled, high-throughput screens using next-generation sequencing-based readouts, and/or preparing screening plasmid libraries from synthesized oligo arrays.
- Experience with CRISPR-Cas systems and/or gene editing and delivery technologies.
- Experience preparing next-generation sequencing libraries (Illumina, PacBio, and/or Nanopore platforms).
If you have a passion for advancing gene editing technologies and desire to be part of a pioneering biotech company, we encourage you to apply and join our ambitious team.
Please apply directly through LinkedIn.
Amber Bio is an equal-opportunity employer and encourages applications from candidates of diverse backgrounds. We value diversity and are committed to creating an inclusive and supportive work environment for all employees.