Engineering Jobs in Cambridge Middlesex County Ma Remote

Salary Range: $90,000k- $115,000 (depending on experience)

Vaxess is developing a pipeline of next-generation therapeutics on our novel micro-array patch platform. With only five minutes of wear-time on the skin, the Vaxess’ patch combines room temperature stability with simplified application to dramatically alter the way that drugs are delivered. Vaxess is committed to enabling products that are not only more effective, but also more accessible to patients around the world.

Research & development at Vaxess is cross-disciplinary, integrating mechanical, industrial, biomedical, and chemical engineering with chemistry, biology, and human factors to address important unmet medical needs. We are seeking a talented, collaborative, and highly motivated engineer to join our growing team. This role offers a unique opportunity to build manufacturing capacity from the ground up to bring innovative technology to the global vaccine and therapeutic market.

Responsibilities:

• Characterize and improve manufacturing process unit operations by designing, executing, and analyzing process development experiments; communicate results via written reports and oral presentations to internal and project teams
• Support manufacturing scale-up by assessing novel equipment, work flows, analytical techniques/PAT, and process configurations
• Support manufacturing operations by incorporating equipment and process improvements within established processes and equipment trains, and by revising manufacturing batch records, SOPs, and other controlled documents to reflect changes; contribute to implementing and maintaining Vaxess’ Quality System.
• Supervise and mentor junior engineer(s) and technicians, including a direct report
• Collaborate closely with cross-functional teams to support product development and manufacturing activities

Qualifications:

• BS in Mechanical Engineering, Biomedical Engineering, or a related discipline
• 2 – 7 years of relevant direct R&D experience within the medical device or biopharmaceutical industries; experience working on combination products is highly desirable
• Demonstrated success using empirical and first-principles models to inform and analyze experiments; experience with statistical methodologies and working with large data sets (e.g. Six Sigma, DoEs, multivariate techniques) is a plus
• Excellent time and project management skills and proven ability to meet goals and deadlines
• Demonstrated abilities to learn new skills and fields, creatively solve challenging technical problems, think independently, and work collaboratively in diverse multidisciplinary teams
• Entrepreneurial spirit and drive to positively impact global human health

At Vaxess, we’re bringing together exceptional talent to drive our product development forward. We value collaboration, curiosity, and a dynamic work environment. To apply, please submit your CV/resume to

Immediate need for a talented Scientist I. This is a 12+ Months contract opportunity with long-term potential and is located in Waltham, MA, USA(Onsite). Please review the job description below and contact me ASAP if you are interested.

Job Diva ID: 26-08545

Pay Range: $ 46-$56 /hour. Employee benefits include, but are not limited to, health insurance (medical, dental, vision), 401(k) plan, and paid sick leave (depending on work location).

Key Responsibilities:

• Develop and optimize robust viral/non-viral vector purification process using advanced knowledge of column chromatography, filtration, and other downstream purification technology
• Lead and conduct viral/non-viral vector purification process development and process analytics
• Develop and optimize robust viral/non-viral vector purification process using advanced knowledge of column chromatography, filtration, and other downstream purification technology
• Develop, conduct, maintain analytical assays such as ELISA, DLS, Octet, QPCR/ddPCR, HPLC, and CE-SDS etc. for in-process sample testing to support process development
• Provide scientific and technical expertise for in-process sample testing activities, including product quality and process impurity methodologies
• Perform troubleshooting experiments and communicate findings with appropriate working groups
• Maintain industry knowledge and keep abreast of new and relevant technologies
• Perform data analysis, contribute to technical reports, external publications, patent applications and internal/external presentations
• Lead scale-up activities to implement a manufacturing process based on DSP development knowledge
• Communicate effectively with internal and external teams, e.g. CDMOs for tech transfer activities
• Mentor and support junior staff and build a culture of support and collaboration

Key Requirements and Technology Experience:

• Key skills: - Purification experience/ Protein Purification Chromatography
• Technical experience in modern analytical techniques such as spectrophotometry, ELISA, DLS, - Late-stage purification experience such as design space mapping and process robustness studies
• PhD in Biotechnology, Biochemistry, Chemical Engineering or related discipline or master’s degree with a minimum of 4 years of relevant experience or a bachelor’s degree with a minimum of 6 years of relevant experience
• Technical experience in modern analytical techniques such as spectrophotometry, ELISA, DLS, Octet, QPCR/ddPCR, HPLC, and CE-SDS
• Significant experience, knowledge and understanding of purification technologies and operations such as:
• Filtration unit operations at various scales, including depth filtration, tangential flow filtration, etc.
• Protein purification chromatography
• Virus clearance and inactivation
• Familiarity with advanced purification technologies and process analytical technologies
• Familiarity with analytical method transfer, analytical method bridging across organizations
• Experience with process technology transfers and performing gap analyses and risk assessments
• Understanding of critical quality attributes and the principles of Quality by Design and ability to apply DOE to downstream development
• Expertise in technical report writing
• Experience in AAV and/or non-viral purification development
• Experience in writing CMC components of regulatory dossiers
• Knowledge of product comparability, target product profile and quality risk assessment activities
• Viral clearance study design and execution
• Late-stage purification experience such as design space mapping and process robustness studies
• Ability to work in Biosafety Level 2, follow safe lab procedures and maintain good laboratory practices (GLPs)
• Ability to work under minimal supervision and function within a collaborative, team-oriented environment
• Excellent organization and communication skills
• Innovative, critical and creative thinker, unafraid of proposing aggressive solutions to complex problems
• Experience with biophysical characterization
• Experience in continuous manufacturing and process analytical technology
• Experience in mentoring junior staff
• Ability to build and nurture cross-functional relationships
• Ability to communicate and represent group in diverse, multi-functional meetings

Our client is a leading Pharmaceuticals industry , and we are currently interviewing to fill this and other similar contract positions. If you are interested in this position, please apply online for immediate consideration

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About the Role

The ideal candidate has hands-on experience in Cesium chloride (CsCl) density gradient ultracentrifugation, ion-exchange chromatography, affinity purification, and tangential flow filtration (TFF), with a strong understanding of purification principles and data analysis.

Responsibilities

• Execute purification processes including CsCl density gradient ultracentrifugation, affinity chromatography (e.g., AVB, CaptureSelect), ion-exchange chromatography (AEX, CEX), and other polishing steps.
• Operate AKTA systems (Avant, Pure, or Pilot) for small- to large-scale purification runs.
• Perform TFF operations for buffer exchange and concentration of intermediate or final products.
• Support experimental design, data collection, and documentation following established procedures and GMP/GLP best practices.
• Assist in troubleshooting and optimization of purification processes.
• Analyze in-process and purified samples using relevant analytical methods (e.g., UV, SDS-PAGE, ddPCR, ELISA, or HPLC).
• Collaborate cross-functionally with upstream, analytical, and manufacturing teams.
• Maintain lab equipment, manage buffers and column inventory, and ensure compliance with safety and documentation standards.

Qualifications

• Education: Master’s degree in biology, biochemistry, chemical engineering, biotechnology, or related field.
• Experience: Minimum 2 years of hands-on purification experience in an academic or industry setting.

Required Skills

• Strong knowledge and practical experience with CsCl density gradient ultracentrifugation, ion-exchange, and affinity chromatography.
• Familiarity with buffer preparation.
• Understanding of basic analytical methods for product characterization.

Preferred Skills

• Strong attention to detail and excellent documentation habits.
• Effective communication and teamwork skills.
• Ability to manage multiple tasks and meet project timelines.

Preferred Qualifications

• Experience in AAV or other viral vector CsCl density gradient and column purification.
• Experience with AKTA systems and Unicorn software.

Experience you will need:

• Ability to read and interpret construction drawings and specifications.
• Understanding of construction methods and materials.
• Proficiency in Excel and spreadsheets.
• Familiarity with CAD software preferred.
• Strong written and verbal communication skills.
• Degree in Construction Management, Engineering, Architecture, or related field preferred.
• Prior construction or estimating experience required.
• 7+ years of experience in Commercial Construction Estimating preferred.
• Minimum 3+ years estimating experience considered.

Company Description

Davis is a vertically integrated real estate investment, development and management firm that leverages five decades of experience, the strength of its leadership team and employees and a diversified portfolio to deliver maximum value for its investors and tenants. Headquartered in Boston and investing across the United States, Davis prides itself on taking a nimble, collaborative approach to delivering best-in-class results from complex opportunities. With $12.8 billion in gross asset value invested through real estate equity, debt and fixed-income securities, Davis today owns a real estate portfolio of approximately 15.2 million square feet of healthcare and life science, industrial, retail, office and hospitality properties and more than 5,800 residential units across the United States. For further information, visit & Responsibilities

Specific responsibilities will include, but are not limited to, the following:

• Ability to autonomously formulate a business plan in coordination with the Residential Vertical and execute all assigned investments involving development being performed directly and passively with oversight responsibilities.
• Strong leadership and people management skills with an ability to oversee team member(s) in the department; completion of tasks, meeting goals, and clear communication.
• Manage the deployment of internal personnel and outside consultants to ensure approved business plans are achieved.
• Improve and implement standard operating procedures relating to project management and reporting.
• Actively participate and contribute on acquisition decisions relating to projects that involve development components and provide support to the firm in assessing the feasibility of new project opportunities.
• Manage the development process from feasibility analysis to final completion including: site acquisition; planning, value engineering, design, and engineering; permitting; financing; marketing and leasing; and construction.
• Assemble, negotiate contracts, and coordinate the project team including: legal counsel; architects and engineers; consultants, general contractors; and other requisite development team members.
• Act as owner’s representative at all government and project related public meetings.
• Strong ability to coordinate programming and design of every aspect of the project including schematic, design development, and construction documents.
• Develop pro-formas, financial sensitivity analysis, budget projections, and critical path schedules.
• Communicate and consult with key internal team members in a regular and timely fashion on project progress, budget, and key issues in accordance with approved business plans.
• Oversee permitting and engineering for related off-site municipal improvements such as roadways and water/sewage improvement.
• Evaluate environmental issues and develop the proper solutions to address them.
• Maintain and cultivate relationships with JV partners and investors and lenders, including marketing development projects to financial partners.
• Represent the Company in the real estate community with respect to business development and other matters.
• Other related duties as assigned.

Skills & Qualifications

• Minimum of 7 years’ experience in real estate (including residential, retail, and/or hospitality), development and construction.
• Travel is expected to be minimal and will occur primarily on an as-needed basis for project or development activities outside of the Boston area.
• An advanced degree in real estate, engineering, construction, or related field.
• Strong experience in all aspects of the development process including planning, permitting, design, construction and finance.
• Proven ability to establish effective relationships with town officials, planning boards and neighborhood groups.
• Demonstrated development track record.
• Effective verbal, written and presentation skills.
• Knowledge of state and local politics and permitting procedures.
• Detail oriented with the ability to read, interpret, and modify plans.
• Prior experience in managing an external team.
• A team-oriented professional with creativity, initiative, and the breadth of real estate development experience.
• The ability to promote the organization to a variety of sophisticated audiences.
• Results-oriented attention to setting goals and getting things done – not merely delegating to others.
• Strategic, creative and analytically minded.
• Highly professional with strong interpersonal skills.
• Flexible, with the ability to work as a team player and relate well to colleagues at all levels of the organization.
• An individual who is organized, detail-oriented, has a sense of urgency
• Decisive, smart, and able to “think three-dimensionally”.
• Able to communicate effectively internally and externally.
• Honesty, integrity and maturity, and the ability to exercise discretion.
• A roll up your sleeves can-do attitude and strong work ethic.
• The ability to juggle multiple tasks, be a self-starter and maintain composure in a fast-paced work environment.
• The ability to be flexible in a dynamic, entrepreneurial environment with high level of energy, enthusiasm and positivity.

COMPENSATION

& BENEFITS:                   Base Salary Range: $210,000- $225,000

                                       Compensation will include a bonus and an attractive benefits package.

We are an equal opportunity employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex (including pregnancy), national origin, age (40 or older), marital status, sexual orientation, gender identity/expression, citizenship, real or perceived disability or handicap, genetic predisposition, veteran status, and/or any other protected category in accordance with applicable federal, state or local laws.