Engineering Journal Jobs in San Ysidro, CA

I work with growing restaurant groups here in San Diego. You are welcome to check out the list on my website , Since we are growing, we need strong leaders. There is a common trait amongst managers that grow and get promoted. They can rally a crew. They understand the basic fundamentals of proper service and the proper way to do things. They work hard and are dedicated to their craft. They are kind but clear. They are serious about the expectations they set and know how to deliver through accountability.

Currently I'm in search of a professional General Manager that has the ability and skill set to operate a high profile, very serious restaurant. Maybe, one of the most substantial spots in San Diego. It is a very dynamic operation with many moving parts and high expectations. You must have previous experience running as the leader of an operation with fine dining stylings with high volume.

To be clear, the base salary is $110,000 and the obtainable monthly incentive payment is up to $50,000 per year. In fact, there is a hope and expectation is that the right person will achieve their incentive every month.

We are looking for a person that builds community, hustles, drives the top and bottom line, continues to learn , sweats about the details and delivers real hospitality while rallying the team to execute on high standards. We currently have several long term brands. You would be responsible for leading three such units after an initial cultural adjustment period of 90 days or so. There is alot to cover and a tremendous learning opportunity.

This a unique opportunity, as you'll lean more about running the business that a typical corporate GM Job. You'll make more of an impact exercising your judgment and taking an ownership mentality. Leadership will work directly with you on a weekly basis and show you the systems required to run and own your own place. When you're really ready for your own place, I'll help you, with your business plan and fundraising if necessary.

The 5 Non-Negotiable Leadership Attributes:

1. Command of the Room

They carry calm, natural authority.

The dining room, bar, and back-of-house feel more controlled and confident when they’re present. They anchor the operation without theatrics.

2. Relentless Standards Keeper

They notice drift early and correct it immediately.

Uniforms, pacing, language, lighting, cleanliness, and service details never “slide.”

They protect the brand even when it’s inconvenient.

3. Coach Who Builds Leaders

They teach judgment, not dependency.

Feedback is direct and timely. Praise is earned. Accountability is consistent.

People get better because of them.

4. Operationally Fluent Financial Thinker

They understand the P&L as a byproduct of daily decisions, not a report to review later.

5. Deep Hospitality Instinct

They understand symbols, ceremony, restraint, and intention.

They know when to touch a table, when to comp quietly, and when to let the room speak for itself.They create trust, not performance.

The 5 Outcomes of Hiring the Right General Manager:

1. Operational Consistency

The guest experience is dependable across shifts, days, and seasons.

Execution does not rely on heroics or constant oversight.

2. A Self-Sustaining Leadership Engine

Strong decisions are made without escalation.

Managers and captains are confident, aligned, and accountable.

The restaurant does not wobble when the GM steps away.A farm league is created growing line level into leaders and shipping leaders out to run other stores.

3. Financial Discipline Without Eroding Hospitality

Labor is intentional. Comps are strategic. Waste is controlled.

The room feels generous, but the business is never sloppy.

Margins improve because execution improves.

4. Credibility and Trust With the Team

Standards are enforced evenly.

Expectations are clear. Feedback is fair and consistent.

People trust leadership decisions — even when they don’t love them.

5. Guest Trust & Reputation Protection

Issues are resolved before they become reviews.

Regulars feel recognized. First-time guests feel taken seriously.

Mistakes strengthen trust because recovery is thoughtful and professional.

If you seriously see yourself having

Job Type: Full-time

Please do not apply if you're not sure or able to pull off these 10 requirements. You must come with General Manager experience. If you have these traits and these words and concepts really resonate with you, thoughtfully answers these questions in your message if you want to be considered:

• What happened to find yourself looking in Indeed for your next gig? What exactly happened ? What was your take away?
• What was the last time you missed a professional goal? What exactly happened ? What was your take away?
• What exact restaurant experience do you have that would help you be ready for this position?
• What would be the name of your autobiography?

Work Location: In person

JT Wimsatt Contracting Co, Inc., a building industry leader, founded in 1992, delivering projects with superior quality, on time and within budget for our clients. JT Wimsatt serves both public and private sector clients with a range of commercial, industrial, residential, government and specialty construction projects.

We are currently seeking a Project Manager for our San Diego location to provide overall management and assume full responsibility for assigned projects and interface with Client/Owner. Reports to Project Executive. Construction experience is a MUST, with a background in structural concrete highly preferred.

Our Benefits include:

• Medical, dental, vision and more
• Basic employee-only health plan and basic life insurance is free to employees
• Competitive salary
• Bonus opportunities
• 401k plan with company match
• Flexible spending and dependent care accounts
• Excellent PTO program, including 8 paid holidays

Duties and Responsibilities

• Works as a team with Project Superintendent.
• Manage assigned Project Engineers
• Ensures the project is planned and staffed according to the budget
• Regularly walk job sites to monitor production and constantly implement improvements.
• Hold weekly meetings with the Project Team to review project data and ensure successful completion
• Plans overall construction schedule
• Tracks project as-built schedule
• Implementation of JTW Project Control Systems.
• Establish project objectives, policies, procedures and performance standards within company policy.
• Manage and be responsible for financial aspects of contracts by ensuring that pricing is completed timely and collected timely from client.
• Monitor/control construction through administrative direction of site superintendents to ensure project is built on schedule and within budget; investigate & resolve risks to profitability.
• Provide strong leadership and guidance to field and site superintendents.
• Initiate and maintain liaison with client/owner and A/E contacts, to facilitate construction activities.
• Participate as requested in the marketing, estimating, bidding and contract negotiations phases of assigned projects.
• Prepares and submits monthly, weekly progress reports and cost reports.
• Represent company/project in meetings with client, subcontractors, etc. as required.
• Review and approve all purchases and ensure Purchase Order/Buy Out process is followed.
• Performs other tasks as directed by supervisor.

Position Requirements

• Structural concrete construction experience is a MUST
• B.S. degree in Civil Engineering, Construction Management, Urban Planning, or relative field
• 8+ years or more experience in managing projects
• Thorough knowledge of contract documents, materials, equipment utilization, scheduling systems/computer software, productivity analysis, construction operations, and cash flow procedures.
• Excellent communication and interpersonal (tact, diplomacy, influence, etc.) skills essential.
• Computer literate with Microsoft Word, Excel, Project, Vista Viewpoint and Primavera software.
• Periodically travel around Southern California.
• Upon hire all candidates must provide proof of legal right to work in the United States and pass a background check, drug screen and physical. No sponsorship available at this time.

About the Role

We are seeking a hands-on eyewear Product Developer to help design, develop, and refine new eyewear products from concept through launch. This role is execution focused but highly collaborative. The ideal candidate combines strong technical product development skills with commercial awareness and an understanding of market trends and customer needs. You will work cross-functionally with executive leadership, sales, marketing, and suppliers to bring high-quality, margin-conscious products to life.

Responsibilities

• Product Design and Development: Develop new products and improve existing ones based on customer insights, data, and company strategy. Translate design intent into manufacturable, scalable products.
• Research and Innovation: Identify emerging materials, technologies, and trends that can differentiate our products in the market.
• Prototyping and Testing: Create, source, and evaluate prototypes. Ensure functionality, fit, durability, and cost targets are met. Iterate quickly and thoughtfully.
• Supplier and Vendor Coordination: Partner with domestic and international suppliers. Evaluate samples, negotiate revisions, manage timelines, and maintain quality standards.
• Cross Functional Collaboration: Work closely with executive leadership, marketing, and sales to ensure product development aligns with go to market strategy.
• Project Management: Manage timelines, milestones, and development calendars to ensure successful launches.
• Documentation and Reporting: Maintain clear documentation of specifications, revisions, costing, and development status.

Qualifications

• Bachelor’s degree in Product Design, Industrial Design, Engineering, or related field.
• 3 to 6 years of experience in product development or consumer product design.
• Strong understanding of manufacturing processes and materials.
• Experience working with overseas suppliers.
• Proficiency in relevant design tools such as SolidWorks, Rhino, AutoCAD, or Adobe Creative Suite.
• Ability to manage multiple projects in a fast-paced environment.
• Optical experience is helpful but not required.

Work Environment

We are a mature but still growing company with strong margins and a collaborative culture. This is not an environment where internal politics, finger pointing, or corporate games are tolerated.

Our values are not posters on a wall. They are lived daily and guide how we interact with our customers, partners, and each other. We expect integrity in decision making, positivity in approach, innovation in thinking, and a spirit of service that extends to everyone we work with, including our own teammates.

We strive to create an environment that is both professional and human. That includes strong benefits and real quality of life. We offer comprehensive health coverage, retirement support, and a workplace that people genuinely enjoy being part of.

Our offices are dog friendly and designed to encourage connection and collaboration. You will find shared meals, great coffee, team events, friendly competition, and yes, the occasional ping pong match or Mario Kart showdown.

We believe people do their best work when they feel respected, supported, valued, and part of something meaningful.

Employees also have access to a fully equipped private onsite gym with showers.

Benefits:

• 401(k) matching
• Dental insurance
• Employee assistance program
• Employee discount
• Flexible spending account
• Health insurance
• Life insurance
• Paid time off
• Parental leave
• Referral program

Job Type: Full-time, Hybrid

Equal Opportunity Statement

We are committed to diversity and inclusivity.

Noon & Associates is an AV-Rated civil litigation firm based in Downtown San Diego, and we’re looking to add a motivated civil litigation attorney to our team. If you enjoy hands-on litigation work, client interaction, and taking real ownership of cases, this could be a great fit. Please submit your resume for consideration. All inquiries are kept strictly confidential.

What You’ll Do

• Manage and support all phases of civil litigation, from pre-trial through resolution
• Take and defend depositions, appear in court, and work directly with clients
• Collaborate closely with experienced attorneys in a fast-moving, team-oriented environment
• Develop strong advocacy skills while handling complex, high-stakes matters

What We’re Looking For

• 2+ years of civil litigation experience
• J.D. from an accredited law school and active California Bar membership
• Strong legal writing, research, and analytical skills
• Experience with depositions and court appearances
• Working knowledge of pretrial, trial, mediation, and arbitration procedures
• Confidence communicating with clients, colleagues, and opposing counsel

Why Noon & Associates

We offer meaningful litigation experience, early responsibility, and direct exposure to clients and strategy. You won’t be siloed—you’ll be involved in real decision-making and case development from the start.

Benefits & Perks

• Medical and dental insurance
• Paid vacation, sick time, and holidays
• Simple IRA with employer matching
• Supportive, collaborative team culture in a downtown San Diego office

About Us

Noon & Associates handles complex civil litigation, including business and commercial disputes, professional liability (legal, accounting, and financial), employment, personal injury, products liability, construction, and architect and engineer litigation. We’re known for our sharp analysis, attention to detail, and proactive approach—often achieving favorable results early in a case. Our clients range from individuals to local, regional, and national companies, including law firms, accounting firms, engineering firms, and insurers.

Frisella Neilson, APC, an established trust and estates law firm, is seeking to hire an experienced attorney. The attorney will be responsible for ensuring quality representation of clients in cases related to trust and estates disputes.

Duties & Responsibilities:

• Manage a caseload of trust and estates matters from intake to resolution.
• Manage deadlines, ensuring consistent and effective case progression.
• Provide accurate and practical advice to clients in and out of court.
• Conduct comprehensive legal research and analysis to develop effective case strategies.
• Effectively communicate with opposing counsel to negotiate matters and resolve disputes amicably.
• Draft legal briefs, correspondence, pleadings, and other legal documents.
• Draft written discovery and responses to written discovery.
• Meet with clients to review responses to written discovery requests, prepare for depositions, and prepare for trial testimony.
• Prepare for and attend client meetings, depositions, mediations, trials, and hearings.
• Document file in accordance with the Firm policies and procedures.
• Travel to courts in and around the State and handle all aspects of litigation of a case.
• Research and interpret laws and regulations and prepare legal opinions.
• Communicate with clients in a manner that develops and maintains client relationships.
• Attend continuing education classes, webinars, and seminars to remain up to date on changes in the law, rules of court or court procedures.
• Perform other duties as assigned.

Required Qualifications & Experience:

• Juris Doctor (J.D.) degree from an accredited law school.
• Active membership in the California State Bar in good standing.
• Experience in civil or probate litigation.
• Experience in the courtroom, taking depositions, drafting discovery, and drafting a variety of motions.
• Strong legal research and writing skills.
• Ability to use email, search engines, internet, Microsoft Products/Office365 and cloud-based products.
• Experience with tracking, recording, and billing time based on the billable hour.
• Communicate with a kind and friendly tone and demeanor.
• Speak clearly and professionally with others inside and outside the firm.
• Strong written, oral, and interpersonal communication skills.
• Generate accurate, clear, timely legal briefing.
• Ability to manage a caseload.
• Collaborate with team members.

Job Type: Full-time

Salary: Commensurate with experience.

Benefits:

• 401(k)
• Dental insurance
• Health insurance
• Paid time off

License/Certification:

• Membership in the California State Bar in good standing. (Required)

Job Summary:

The Cordia San Diego team is seeking a Plant Manager to be responsible for all aspects of the safe, reliable and sustainable operation and maintenance of the San Diego chilled water production plants and distribution systems on a 24/7/365 basis. Reporting to the Southwest General Manager, the Plant Manager will oversee safety, operational reliability and efficiency, maintenance and repair, environmental reporting, capital and expense budget execution, oversight of projects, record keeping and administration, personnel management, training and development, and adherence to corporate policies and regulatory agency requirements.

Principle Responsibilities/Key Results Areas:

• Safety - Leads all aspects of safety in operations pertaining to employees, contractors and visitors. Ensures all work is executed in accordance with Cordia safety policies. Performs periodic audits, reporting and other requirements of the safety program. Encourages a strong safety culture thru 2-minute drills and hazard and near miss reporting.
• Operations and Maintenance - Responsible for all aspects of plants and distribution system including equipment condition, maintenance, repair, operation, replacement, and modification. Develops and implements operating and maintenance strategies and procedures to meet or exceed reliability and efficiency goals while meeting safety, regulatory and customer contractual requirements.
• Continuous Improvement - Identifies and implements opportunities for safety, reliability, and efficiency improvements. Leads problem solving analysis while sharing lessons learned and best practices.
• Manage Personnel - Accomplishes organizational objectives by managing site personnel. Maintains staff by recruiting, selecting, orienting, training and coaching employees. Communicates job expectations, establishes goals, monitors, and appraises job results.
• Culture and Employee Engagement - Consistently communicates corporate culture and values to all employees.
• Technical Leadership - Directs and coaches technical teams in the day-to-day performance of maintenance and operations processes to ensure safe, reliable, and cost-effective operation and maintenance of all plant equipment and systems. Responsible for development, implementation and periodic updating of safety, environmental, operations and maintenance training programs.
• Customer Support - Supports customers and Business Development by providing plant tours, usage data, technical expertise, etc. Analyzes billing related customer data for accuracy and completeness.
• Project Management - Plans and executes major maintenance and capital replacement projects utilizing Cordia Project Management Policies. Provides coordination between contractors, consultants, and material suppliers.
• Budgeting, Forecasting and Variance Analysis - Provides input to and executes both expense and capital budgets. Provides monthly revenue and cost variance analysis and mitigates any cost exceedances or revenue shortfalls. Reviews and approves utility and vendor invoices. Assists with utility bill estimations for beginning of month accruals and budget development.
• Track and Report - Develops and reviews production reports, daily/weekly logs, electrical, water and fuel consumption and other key data to ensure key results are met. Investigates and resolves any discrepancies. Develops and manages tracking and reporting tools to evaluate personnel and equipment performance to identify paths for improvement for each.
• Regulatory Compliance - Implements and adheres to all applicable environmental regulations including air quality, hazardous material disposal and storage, wastewater discharge, employee training, and miscellaneous periodic inspections & certifications.
• Inventory Management - Responsible for ensuring adequate supply of chemicals, spare parts and other plant supplies.

Preferred Qualifications:

Experience & Education

• 4-year degree or equivalent in any field (engineering preferred) with (10) years of experience working in District Energy, power, oil & gas, military, or similar industries.
• Candidate should have at least 5 years of leadership experience with demonstrated strong analytic and presentation skills.
• Strong written and verbal skills are required in managing a diverse cultural workforce.
• Proven skills in leading and coaching company personnel and contractors.
• Detailed technical understanding related to thermal systems including startup, operations and maintenance. Ability to formulate appropriate technical plans and objectives and direct their effective accomplishment through company personnel and contractors.
• Hands on maintenance and troubleshooting experience with central cooling plants preferred.

Knowledge & Skills

• Should be generally versed in the operation and maintenance of chilled water production plants, distribution systems and related control systems, water treatment, instrumentation and metering devices, pumps, turbines, air systems, etc.
• Superior interpersonal skills and demonstrated ability to effectively communicate (written and verbal) at all levels of the organization.
• Demonstrated ability to establish and maintain a positive and professional working relationship with all individuals.
• Demonstrated ability to exercise sound judgment and objective reasoning and to identify problems and solutions without constant guidance.
• Proven planning and organizational skills.
• Ability to learn quickly and work under pressure with a high tolerance for stress.
• Displays good judgment and willingness to take responsibility and initiative to make decisions within scope of responsibility.
• High level of proficiency in Microsoft Excel, Word and Outlook and familiarity with PowerPoint.
• Experience and competency with Netsuite or similar enterprise financial and procurement system(s).
• Uses discretion concerning confidential and sensitive company information.

Working Conditions

• Extended and off-hours work required based on plant operational needs
• Work is performed in an administration office environment that requires physical mobility as well in a plant environment with large loud machinery
• Some business travel is required. This position is responsible for various plant locations within the city and therefore reliable personal transportation is required
• Must possess a valid Driver License at all times with a good driving record

We're seeking a Sr. Automation Engineer for our client's Manufacturing Technology & Transfer (MTT) team to lead liquid handling automation in consumables manufacturing environment.

The ideal candidate will own the full lifecycle — from proof-of-concept to validation — in a regulated GMP setting. Must have experience with Automated Liquid Handling Systems and Software integration with LIMS/MES.

• Type: W2 Contract
• Start Date: April 1, 2026
• End Date: December 31, 2026
• Pay Rate: $52.00 – $64.75/hr W2 plus benefits

What You'll Do

Automation & Development

• Owns the full implementation of liquid handling automation systems in regulated lab and manufacturing settings
• Develops complex scripts and recovery methods for new assays/workflows, including error handling, custom liquid classes, and simulation runs

Validation & Quality

• Validates automated applications to ensure accuracy, precision, and repeatability
• Applies structured problem-solving to overcome technical roadblocks in system deployment

Process Improvement

• Drives continuous improvement initiatives to enhance system performance and end-user experience
• Provides ongoing technical support and troubleshooting for protocols and instrumentation

Documentation & Training

• Develops and maintains comprehensive documentation, training materials, and internal process guides
• Delivers software and hardware training to internal customers at all skill levels

Strategy & Collaboration

• Influences project and program decisions at critical cross-functional interfaces
• Stays current on industry developments, emerging technologies, and regulatory expectations to guide long-term automation strategy

Requirements

• Hands-on expertise with liquid handling platforms (Hamilton, Tecan, Beckman, Agilent, Lynx, etc.) and peripheral integration
• Deep knowledge of method development, error recovery, liquid class optimization, and LIMS/MES integration
• Proficiency in C# and/or Python
• Strong troubleshooting skills with a track record of resolving production-critical issues
• Familiarity with SDLC and validation procedures in regulated environments
• Ability to manage vendors, contractors, and project timelines independently
• Clear communicator across technical and non-technical audiences

Qualifications

• Bachelor's degree in Life Sciences, Chemistry, Engineering, or Computer Science + 5 years of experience OR
• Master's degree + 3 years OR
• PhD (no experience required) OR
• Equivalent work experience considered

Please apply today!

TAB Consultancy Services LLC is a workforce development and technology training organization focused on preparing individuals for high-demand careers in IT, Cybersecurity, Cloud Computing, Networking, and AI-enabled technologies.

Our programs combine industry-recognized certifications, hands-on training, and structured apprenticeship pathways designed to connect trained candidates with real employment opportunities.

TAB partners with employers, workforce development organizations, and community partners to help businesses build sustainable talent pipelines while helping individuals launch careers in technology.

As we continue expanding our apprenticeship programs and employer partnerships, we are seeking a results-driven Account Executive – Apprenticeship Solutions to help grow our employer network and generate new hiring opportunities.

This is a hybrid role based in San Diego, California.

The position allows for a combination of remote work and in-person meetings, and will require occasional local travel for:

• Employer meetings
• Networking events
• Chamber of Commerce events
• Workforce development events
• Industry conferences

This is a 1099 independent contractor position designed for a self-motivated, entrepreneurial sales professional who can independently manage a full sales pipeline from lead generation through deal closure.

Many organizations struggle to find qualified entry-level technology talent.

TAB helps employers solve this challenge through structured apprenticeship programs that provide access to trained candidates in areas such as:

• Cybersecurity
• Cloud Computing
• Network Engineering
• IT Support
• AI & Automation

As an Account Executive – Apprenticeship Solutions, you will play a critical role in helping employers build future-ready teams while helping individuals launch careers in technology.

This role is ideal for a high-performing sales professional who enjoys building relationships, developing new business opportunities, and driving measurable results.

You will own the employer acquisition pipeline from start to finish, including:

• Lead generation
• Employer outreach
• Relationship building
• Proposal development
• Closing employer partnerships

You will act as the primary driver of new employer partnerships for TAB’s apprenticeship programs.

• Identify and engage small and mid-sized businesses, government contractors, and enterprise employers
• Generate employer leads through outreach, networking, and referrals
• Conduct outreach via LinkedIn, email campaigns, phone calls, and networking events
• Stay informed on local hiring trends and workforce needs

• Schedule and lead discovery meetings with employers
• Present TAB’s apprenticeship hiring model and talent solutions
• Build relationships with HR leaders, hiring managers, and IT leaders
• Attend industry and workforce development events to build employer connections

• Develop customized talent solutions based on employer hiring needs
• Guide employers through the apprenticeship partnership process
• Maintain consistent follow-up to move opportunities through the pipeline
• Collaborate with internal teams to ensure smooth onboarding after employer agreement

• Own and manage the employer sales pipeline from initial contact to signed partnership
• Track outreach activity, meetings, and pipeline progress
• Maintain CRM records and report performance metrics
• Forecast pipeline activity and employer partnerships

• Build relationships with workforce organizations, chambers of commerce, and industry groups
• Participate in workforce development initiatives and employer engagement events
• Identify opportunities for employer partnerships and long-term collaboration

Performance in this role will be measured based on monthly targets such as:

• 200 employer leads generated
• 40 employer meetings scheduled
• 10 new employer partners onboarded
• 10–20 candidate placements

Additional expectations include maintaining consistent outreach and pipeline activity to support these targets.

This role reports directly to the Director of Operations and works closely with internal teams including:

• Training & Instruction
• Candidate Success
• Workforce Partnerships
• Operations

You are a self-motivated, results-driven sales professional who thrives in an independent environment.

You are comfortable owning a full sales cycle and managing a high-volume pipeline of employer opportunities.

You enjoy building relationships and creating solutions that help employers solve real workforce challenges.

• Proven success in business development, sales, or employer partnerships
• Experience managing a full sales pipeline from prospecting to closing
• Strong ability to generate and convert employer leads
• Excellent relationship-building and communication skills
• Experience with B2B sales outreach and networking
• Strong organizational skills and ability to manage multiple opportunities
• Comfort working independently in a results-driven environment

Experience in one or more of the following areas is a plus:

• Workforce development programs
• Apprenticeship programs
• Tech recruiting or staffing
• EdTech, training, or talent development services
• IT, cybersecurity, or technology workforce sectors

Candidates should be comfortable using tools such as:

• LinkedIn Sales Navigator
• CRM platforms (HubSpot, GoHighLevel, Airtable, or similar)
• Email outreach tools (Hunter, Apollo, or similar)
• Zoom or webinar platforms
• Google Workspace or similar productivity tools

This role is offered as a 1099 Independent Contractor position.

Compensation structure will be discussed during the interview process.

If you are a driven sales professional who enjoys building partnerships and creating opportunities, we encourage you to apply and help us expand access to technology careers through apprenticeship pathways.

TAB Consultancy Services LLC is an Equal Opportunity Employer. We are committed to creating a diverse and inclusive environment and welcome applicants of all backgrounds.

All qualified applicants will receive consideration for opportunities without regard to race, color, religion, gender, gender identity, sexual orientation, national origin, age, disability status, veteran status, or any other characteristic protected by applicable law.

We believe diversity strengthens our mission and our ability to serve employers and communities.

Job Title: QA Consultant (GxP)

Location: San Diego, CA (On-site)

Position Type: Contract / Consultant

Department: Quality Assurance

Reports To: Site Quality Head / Director, QA

Hours requirement: 8 to 5; may need to have some flexibility to work earlier/late as needed

About Us

Based in San Diego, our site operates as a clinical-stage biopharmaceutical facility utilizing unique and proprietary genetic engineering platform technologies to create next-generation cell and gene therapies with the capacity to cure. We are passionate about making an impact on patients' lives with the development of our CAR-T therapies in various cancers and gene therapies for rare diseases. Our goal is to deliver potential single-treatment cures for patients in need.

Position Summary

The Quality organization is seeking an experienced QA Consultant (GxP) to join our team in San Diego, CA. In this on-site contracted role, you will lead the enhancement and maintenance of local Quality Systems, with a primary focus on the Quality Management System (QMS), Electronic Data Management System (EDMS), Document Control, and overall Quality Assurance functions.

You will ensure compliance with regulatory requirements while supporting site-specific needs. This role is integral to the overall GxP Quality system, including processes such as Change Control, Deviation, CAPA, Training, and Document Control, as well as tracking and reporting Quality System Metrics. You will collaborate closely with cross-functional GxP partners including QA, QC, Manufacturing, Validation, Supply Chain, Facilities, and Clinical teams.

Key Responsibilities

Support concurrent activities for legacy Quality systems during QMS integration and system migration phases.

Provide QA oversight for approximately 125 updated SOPs and manual/paper-based systems.

Monitor quality metrics and dashboards to reduce overdue records and maintain effective QMS controls.

Operate and support legacy Quality systems during the transition to new platforms.

Oversee and execute Document Control activities for GxP documents, including manufacturing, clinical, and product quality records.

Assist in managing the GxP Training Program and deliver training on Quality System topics (e.g., Annual GMP Training, Change Control, Deviation, CAPA).

Collaborate with Change Control, Deviation, MRB, and CAPA owners to ensure timely completion and compliance of quality records.

Perform operational functions within the ComplianceWire Learning Management System (LMS) and Qualio (EDMS).

Support continuous improvement efforts for events within EDMS and LMS.

Work with document owners to ensure timely periodic review of procedures.

Assist in the creation and revision of SOPs, policies, forms, templates, and reporting tools.

Generate and trend quality metrics, communicating findings to leadership.

Support internal and external audits, including regulatory agency or partner audits, and assist in executing corrective action plans.

Review and approve paper-based quality documentation and electronic quality records.

Promote a culture of quality, teamwork, and accountability with a patient-first mindset.

Align daily activities with department goals and company values.

Ability to lift up to 20 pounds as needed.

Qualifications

Education: Bachelor’s degree in Life Sciences or related discipline (an equivalent combination of education and experience may be considered).

Experience: Minimum of 8 years of experience in a GxP environment (pharmaceutical, biotech, or cell/gene therapy manufacturing preferred).

Technical Skills:

Strong knowledge of Quality Management Systems in a cGxP manufacturing environment.

Proficiency in core Quality systems: Change Control, Deviations, CAPA, Document Control, and Training.

Hands-on experience with Electronic Document Management Systems (EDMS) and Learning Management Systems (LMS) such as ComplianceWire or Qualio.

Advanced proficiency in Microsoft Office Suite (Excel, PowerPoint, Word).

Competencies:

Exceptional written and verbal communication skills.

Strong attention to detail and ability to manage multiple projects simultaneously.

Proven ability to work independently and collaboratively in a fast-paced, dynamic environment.

Experience developing training materials and delivering training to employees.

Demonstrated ability to write and revise SOPs, work instructions, and Quality System documents.

Location: San Diego, CA 

Seniority Level: Research Associate (RA) / Senior Research Associate (Sr. RA) 

Employment Type: Full-time 

About OliX Pharmaceuticals 

OliX Pharmaceuticals is a clinical-stage biotechnology company developing next-generation RNA interference (RNAi) therapeutics. Our proprietary asymmetric siRNA (asiRNA) platform enables precise, durable gene silencing and supports delivery platforms such as GalNAc-asiRNA for liver-targeted therapies and cp-asiRNA for local delivery (skin, eye, lung). Active clinical programs and global partnerships (including Eli Lilly, L’Oréal, and Hansoh Pharmaceutical) provide a strong foundation for discovery and development. By joining OliX, you’ll help shape the next generation of RNA medicines. 

Role Summary 

We are seeking a hands-on Research Associate / Senior Research Associate to support the synthesis, deprotection, purification, and analysis of chemically modified oligonucleotides that enable OliX’s RNAi pipeline. You will operate and maintain key instrumentation (e.g., HPLC/UHPLC, preparative LC, TFF, UV–Vis), document work in SOPs, batch records, and reports, and collaborate closely with RNAi chemistry, medicinal chemistry, and biology teams to advance discovery and preclinical programs. 

Key Responsibilities 

• Execute (or Help) solid-phase oligonucleotide synthesis (SPS) and downstream processing (cleavage, deprotection, desalting). 
• Purify and polish oligonucleotides using OPC, analytical and preparative HPLC/UHPLC, and UPLC; perform buffer exchange and concentration via TFF. 
• Develop and optimize purification methods and in-process controls to improve yield, purity, and throughput. 
• Perform analytical characterization (UHPLC/LC–MS, UV–Vis); compile CoAs, batch records, and data summaries. 
• Operate, maintain, and troubleshoot lab instruments; coordinate vendor service when needed. 
• Author and revise SOPs, work instructions, and technical reports; ensure data integrity and traceability. 
• Work cross-functionally with medicinal chemistry and biology teams to align materials specifications and timelines. 
• Maintain safe, compliant laboratory operations and good housekeeping (5S); participate in EHS initiatives. 
• (Sr. RA) Mentor junior team members; lead small method-development or process-improvement projects. 

Qualifications 

Required (RA): 

• B.S. in Chemistry, Biochemistry, Chemical Engineering, or related field with 0–3+ years of relevant lab experience (industry or academic core facility). 
• Hands-on experience with oligonucleotide purification (e.g., OPC, HPLC/UHPLC, preparative HPLC in anion exchange and reverse phase chromatography) and basic analytical techniques (UV–Vis, KF, etc). 
• Familiarity with solid-phase synthesis of workflows and routine instrument maintenance. 
• Strong record-keeping and communication; proven ability to meet deadlines and work effectively in a team. 

Required (Sr. RA): 

• B.S./M.S. in a related field with 3–6+ years of relevant industry experience in oligonucleotide synthesis/purification. 
• Demonstrated proficiency in method development/optimization for oligo purification and in-process analytics. 
• Experience drafting SOPs/batch records and mentoring junior staff. 

Preferred (both levels): 

• Experience with LC–MS data acquisition/interpretation for oligonucleotides. 
• Exposure to nucleoside/nucleotide building blocks or bioconjugation workflows supporting RNAi platforms. 
• Familiarity with TFF operations and scale-up considerations. 

Why Join OliX 

• Contribute directly to an innovative RNAi pipeline with active clinical programs and world-class partnerships. 
• Collaborative, growth-focused environment with cross-functional exposure. 
• Competitive compensation and benefits package (medical, dental, vision, 401(k), equity eligibility, paid holidays/year-end shutdown, stock options). 
• Base salary range of $60,000 – $90,000 (depending on experience and qualifications) 

Work Environment 

• Onsite laboratory role with routine handling of chemicals and analytical instrumentation. 
• Some lifting (up to ~50 lb) and extended periods at the bench or operating instrumentation. 
• Occasional off-hours support during critical runs. 

OliX Pharmaceuticals is an equal opportunity employer. We celebrate diversity and are committed to creating an inclusive environment for all employees.