Jobs in Needham Massachusetts

The Opportunity: Contribute To The Growth Of Your Career

We’re passionate about delivering unmatched value—not only for our customers, but for our global talent community. As we continue to scale and evolve our hiring practices across markets, technologies, and business units, we are seeking a Principal Talent Acquisition Technology & Strategy Specialist to help shape the future of how talent finds, experiences, and joins our organization.

This is a high‑impact, highly visible, role for an individual contributor, strategic problem solver who thrives at the intersection of process optimization, TA technology, analytics, and global engagement. You will independently lead enterprise‑level initiatives designed to strengthen operational excellence, improve candidate and hiring‑manager experiences, and align TA processes with our long‑term business strategy. This is a hybrid position based in our Framingham, MA offices.

What You Will Do:

Drive Global Talent Acquisition Innovation

• Lead major process improvement initiatives across the global TA function, applying design thinking, lean methodologies, and market standards
• Develop future‑state TA practices by influencing the adoption of technology, analytics, and process enhancements that increase speed, quality, and scalability while improving the candidate, manager and recruiter experience

Partner Strategically Across the Organization

• Partner with Global TA leadership, TA Managers, HR, and cross‑functional business partners to understand emerging needs and translate them into actionable strategies
• Serve as a strategic advisor for TA initiatives that support enterprise priorities, including:

Talent attraction and top‑of‑funnel optimization

• Consistent and efficient use of TA technology
• Vendor management and organizational procedures

Lead Technology, Reporting, and Analytics Excellence

• Research best‑in‑class TA tools, processes, and metrics—evaluating return on investment and recommending improvements that align with the TA technology roadmap
• Coordinate and troubleshoot Workday, while supporting data and reporting needs across Workday, Phenom People, and Power BI
• Partner with IT and HRIS to prioritize and implement system enhancements

Champion Operational Excellence

• Support training, resource development, and adoption of standard processes across global TA teams.
• Partner with HR PMO to align project prioritization with business goals.
• Identify bottlenecks throughout the hiring funnel using data and analytics, recommending process improvements grounded in external benchmarks and market trends.
• Lead components of onboarding communications and coordinate related system workflows.

Who We Are Looking For:

The ideal candidate will bring a blend of technical proficiency, critical thinking, and operational rigor as well as the following:

• Strong proficiency in Microsoft Office and HR/Talent systems, including:
• Workday, Power BI, Phenom People, HireVue, Microsoft Bookings, SharePoint, Textio, First Advantage, and ServiceNow
• Experience using technology to build consistency, efficiencies, and actionable reporting across the hiring lifecycle
• Ability to analyze data to uncover trends, gaps, and opportunities—and use those insights to influence partners and inspire change
• Knowledge of external labor market trends, TA benchmarks, candidate behaviors, and recruitment innovations
• Independent decision‑making and ownership of high‑visibility, cross‑functional projects
• Ability to handle ambiguity and adapt to shifting business needs
• Strong interpersonal skills with the ability to facilitate training, guide user adoption, and build trust across global teams
• Dedication to maintaining up‑to‑date playbooks, resource guides, and process documentation
• Some travel required (including international travel)

This position has a starting salary range of $92,900.00 to $118,500.00 per year. Actual starting pay is determined by a number of factors, including relevant skills, qualifications, and experience. This position is eligible for an annual incentive as well as long-term incentives.

At TJX Companies, every day brings new opportunities for growth, exploration, and achievement. You’ll be part of our vibrant team that embraces diversity, fosters collaboration, and prioritizes your development. Whether you’re working in our four global Home Offices, Distribution Centers or Retail Stores—TJ Maxx, Marshalls, Homegoods, Homesense, Sierra, Winners, and TK Maxx, you’ll find abundant opportunities to learn, thrive, and make an impact. Come join our TJX family—a Fortune 100 company and the world’s leading off-price retailer.

Job Description:

Reporting into the Senior Vice President, Corporate Human Resources, the Assistant Vice President, HR Business Partner will provide thought leadership, strategic counsel, advisory and consultative services to business leaders across the corporate organizations, both domestically and internationally, as appropriate.

Responsibilities:

• Contributes to the business strategy by helping business leaders to identify, prioritize, and build organizational capabilities, behaviors, structures and processes
• Focused on identifying and implementing strategic talent solutions in support of evolving corporate organizations; ensuring the overall organization and culture are designed around strategic talent pipeline with a heavy focus on talent development, succession planning, and a culture of inclusion
• Model and build leadership capability at the team and individual level, inclusive of providing high level coaching and counsel to those leaders
• Reviews and benchmarks the internal and external environment to improve the HR practices and identify new opportunities where HR can add value to the business
• The AVP HRBP will collaborate with peers and team and leverage HR’s Centers of Expertise (COE’s) and the HR Operations Support Center for business solutions, guiding the acquisition, staffing, development, and retention of TJX Associates
• Manages and directs the work of more than three full-time Associates. Interviews and recommends the hiring of associates. Evaluates associate performance, recognizing Associates through reward and discipline. Recommends career development and termination of associates. Oversees ongoing functional training of Associates.

Requirements:

• Minimum of 10 to 15 years of related HR business and management experience with experience developing and implementing strategic talent initiatives
• Bachelor’s Degree or equivalent job experience
• Track record of solving complex organizational talent related challenges
• Experience with change management and leading organizational change
• Demonstrated agility in learning and adapting strategies to market realities
• Facilitates effective workforce planning to identify the capacity and capability of the organization to deliver its short and long-term objectives
• Accountable for assessing and developing talent across the department including building a diversified talent pool to fill key current and future positions and ensuring development plans that support Associate growth and development
• Mentors the team on relationship management and business sense and influences and generates innovative business ideas
• Act as a collaborative partner with leaders and positively influences management
• Strong demonstrated leadership presence
• Ability to use HR reporting and analytics to generate insights and present findings back to the business
• Demonstrated understanding of project management principles with experience in leading and/ or partnering on large-scale organization change efforts
• Basic knowledge and use of Microsoft; Word, Excel, PowerPoint, Teams
• Progressive knowledge of Human Resources
• Collaboration & Influencing skills
• Strategic prioritization & planning skills
• Ability to build and develop highly effective teams
• Ability to analyze and interpret financial reports
• Coaching, mentoring, providing counsel and guidance

Benefits include Associate discount; 401(k) match; medical/dental/vision; HSA; health care FSA; life insurance; short/long-term disability; paid holidays/vacation /sick/bereavement/parental leave; EAP; incentive programs for management; auto/home insurance discounts; tuition reimbursement; scholarship program; adoption/surrogacy assistance; smoking cessation; child care/cell phone discounts; pet/legal insurance; credit union; referral bonuses. All benefits are subject to applicable plan or program terms (including eligibility terms) and may change from time to time. Contact your TJX representative for more information.

In addition to our open door policy and supportive work environment, we also strive to provide a competitive salary and benefits package. TJX considers all applicants for employment without regard to race, color, religion, gender, sexual orientation, national origin, age, disability, gender identity and expression, marital or military status, or based on any individual's status in any group or class protected by applicable federal, state, or local law. TJX also provides reasonable accommodations to qualified individuals with disabilities in accordance with the Americans with Disabilities Act and applicable state and local law.

Company Description

Jammin With You is a dynamic and rapidly growing children's music education organization. We provide high-energy classes, private instrument lessons, school enrichment, and performance programs. Our mission is to combine expert music pedagogy with a fun and engaging approach, helping children build skills, confidence, and a lifelong love of music. We are passionate about fostering creativity and growth through music education.

Role Description

We are seeking a part-time Private Music Teacher. As a JWY teacher, you will be responsible for conducting one-on-one music lessons in students' homes, focusing on piano/voice/guitar/drum instruction and music theory. Your role will also include preparing students for performances, fostering their enthusiasm for music, adapting teaching methods to meet individual needs, and communicating progress with families and guardians.

Qualifications

• Strong proficiency in Music Theory and Music Education
• Skilled in Music Performance and instruction
• Passion for teaching and inspiring a love of music in children
• Strong communication skills to engage with students and their families
• Organizational skills and adaptability to tailor lessons to students' unique needs
• Bachelor's degree in Music, Music Education, or a related field
• Experience teaching music to children is highly desirable

Tax Manager

Want to make an impact?

The Tax Manager reports directly to the Assistant Vice President of Employment & Environmental Tax and manages 2 Analysts. The team supports TJX's global mobility finance and employment tax processes, ensuring compliance with local and international tax regulations while supporting associates on assignment. Acting as a key liaison across Tax, Payroll, Treasury, Finance Shared Services, HR, and Legal, the position provides technical expertise and guidance on global mobility, expatriate taxation, employment tax matters and reward & benefit programs.

What You'll Do:

Global Mobility:

• Ensure timely and accurate information for expatriate and localized associates’ tax returns.
• Oversee compensation reporting and local payroll tax withholdings.
• Manage corporate and individual obligations under the Global Mobility Program.
• Liaise with third-party providers to ensure accurate reporting and compliance.
• Review and approve tax equalization calculations and related payments/credits.
• Act as primary contact with tax authorities for expatriate-related issues.
• Develop annual expatriate budgets and update as needed.
• Provide robust and accurate accounting advice and solutions for all non-routine transactions to the local country legal entities
• Support payroll related expat GL accounts and balance sheet reconciliations.
• Prepare tax equalization accrual reconciliations.
• Act as finance SME for domestic relocation policies.

Employment Tax:

• Partner with and provide support to Legal and HR on reward and benefit programs.
• Advise on tax aspects of new associate benefits, programs, and policies, including Benefits in Kind.
• Collaborate with Finance and business partners on expense policy design and compliance.
• Support local accounting and payroll teams in accurate employment tax reporting.

What You'll Need:

• 5+ years of relevant income tax or global mobility tax experience in international environment
• Bachelor’s Degree in Accounting or related equivalent preferred
• CPA or Master’s in Taxation or Accounting preferred
• Strong interpersonal and managerial skills to lead professional staff
• Strong technical knowledge of global mobility and employment tax
• Excellent communication and influencing skills
• Deep understanding of internal and regional tax regulations and reporting requirements
• Ability to manage complex, cross-border processes
• Proactive, detail-oriented, and solution-focused
• Experience with influencing cross-functionally and globally to deliver excellent results
• Capable of working with the teams and associates across multiple geographies including, Europe and Australia

Benefits include Associate discount; 401(k) match; medical/dental/vision; HSA; health care FSA; life insurance; short/long-term disability; paid holidays/vacation /sick/bereavement/parental leave; EAP; incentive programs for management; auto/home insurance discounts; tuition reimbursement; scholarship program; adoption/surrogacy assistance; smoking cessation; child care/cell phone discounts; pet/legal insurance; credit union; referral bonuses. All benefits are subject to applicable plan or program terms (including eligibility terms) and may change from time to time. Contact your TJX representative for more information.

In addition to our open door policy and supportive work environment, we also strive to provide a competitive salary and benefits package. TJX considers all applicants for employment without regard to race, color, religion, gender, sexual orientation, national origin, age, disability, gender identity and expression, marital or military status, or based on any individual's status in any group or class protected by applicable federal, state, or local law. TJX also provides reasonable accommodations to qualified individuals with disabilities in accordance with the Americans with Disabilities Act and applicable state and local law.

Location:

USA Home Office Framingham MA 550 Cochituate Rd

This position has a starting salary range of $103,900.00 to $134,900.00 per year. Actual starting pay is determined by a number of factors, including relevant skills, qualifications, and experience. This position is eligible for an annual incentive as well as long-term incentives.

VWR is hiring! We are seeking a detail-oriented, team collaborator to join our team as a Lab Furniture Sales Specialist, supporting our New England territory.
The Furniture Specialist is a self-starter that works collaboratively with local sales representatives, under limited supervision, to work with existing and new customers across many segments (pharma, healthcare, commercial, electronics manufacturing, education, research, etc) to outfit their laboratory space with a myriad of laboratory furnishings. This is a highly active position that requires interacting with higher level decision makers, along with the architects, corporate real estate brokers, and general contractors.
If you are an energetic professional who is interested in joining a world class sales organization - let's talk!

The team

Avantor's Lab Furniture Sales team works within the matrix of general sales representatives, supply partners, operations, project managers, and customer service teams to deliver complete furniture solutions. This includes going from concept to installation of laboratory furnishings in renovations, expansions, tenant improvements, or similar projects. Other providers can deliver a lab, but delivering one that is versatile, flexible, and ready for science, takes a foundation and expertise that can be uniquely found here at Avantor and within your team.

What we're looking for

• Education: Bachelor's Degree, required
• Experience: 5+ years sales experience, preferably in laboratory, construction material sales, systems furniture, or other furnishings. Space planning and/or construction renovation experience preferred.

• Technical: Familiarity with products in CSI divisions 10, 11, 12
• Preferred Qualifications:

• Advanced Excel and analytical skills
• Experience working a complex/matrix environment
• Salesforce and SAP experience
• Project Management and ability to use AutoCAD/Revit
• Experience developing business relationships with owners and executive level decision makers, along with architects, engineers, general contractors, facilities managers, and EH&S personnel.
• Experience building a business case and delivering ROI to all levels within an organization (including C-suite)

How you will thrive and create an impact

• Be a self-starter that exhibits drive, judgement, and influence; is motivated, recognizes opportunities, communicates ideas and acts with little direction in a fluid and matrixed environment
• Understand customer needs through relationship building and interpersonal skills while asking clarifying questions to ensure accurate and timely delivery of solutions
• Build and lead our strategy deliver our strategic portfolio with customers across various markets.
• Pitch value proposition to potential customers using our Design Showroom, Revit tools, web platforms
• Screens potential business deals by analyzing market strategies, deal requirements and the impact to financials
• Maintain strong external partnerships with manufacturers and extended selling teams
• Exhibit curiosity both with customers and within the Avantor team
• Ability to travel 30% (customer sites, meetings, overnights, etc.)

The above statements are intended to describe the general nature and level of work being performed by employees assigned to this classification. They are not intended to be construed as an exhaustive list of all responsibilities, duties and skills required of employees assigned to this position. Avantor is proud to be an equal opportunity employer.

Why Avantor?

Dare to go further in your career. Join our global team of 14,000+ associates whose passion for discovery and determination to overcome challenges relentlessly advances life-changing science.

The work we do changes people's lives for the better. It brings new patient treatments and therapies to market, giving a cancer survivor the chance to walk his daughter down the aisle. It enables medical devices that help a little boy hear his mom's voice for the first time. Outcomes such as these create unlimited opportunities for you to contribute your talents, learn new skills and grow your career at Avantor.

We are committed to helping you on this journey through our diverse, equitable and inclusive culture which includes learning experiences to support your career growth and success. At Avantor, dare to go further and see how the impact of your contributions set science in motion to create a better world. Apply today!

Pay Transparency

The expected pre-tax pay for this position is,

This reflects base salary.

This position is subject to incentive compensation, where the expected pre-tax Target Cash Opportunity ("TCO") for this position is based on the achieved sales and in the amount/range of,

Actual pay may differ depending on relevant factors such as prior experience and eligible geographic location.

TCO is defined as Base Salary + Target Sales Incentive (Sales Incentive eligible role only).

EEO Statement:

We are an Equal Employment/Affirmative Action employer and VEVRAA Federal Contractor. We do not discriminate in hiring on the basis of sex, gender identity, sexual orientation, race, color, religious creed, national origin, physical or mental disability, protected Veteran status, or any other characteristic protected by federal, state/province, or local law.

If you need a reasonable accommodation for any part of the employment process, please contact us by email at let us know the nature of your request and your contact information. Requests for accommodation will be considered on a case-by-case basis. Please note that only inquiries concerning a request for reasonable accommodation will be responded to from this email address.

For more information about equal employment opportunity protections, please view the Know Your Rights poster.

3rd Party Non-Solicitation Policy:

By submitting candidates without having been formally assigned on and contracted for a specific job requisition by Avantor, or by failing to comply with the Avantor recruitment process, you forfeit any fee on the submitted candidates, regardless of your usual terms and conditions. Avantor works with a preferred supplier list and will take the initiative to engage with recruitment agencies based on its needs and will not be accepting any form of solicitation.

In this role, you will report to the Territory Area Manager and will work closely with the Avantor's Advanced Laboratory Services professionals to serve our customers by performing customized, mission-based lab work and research protocols that help return time back to science.

Location: Cambridge, MA

Shift: Monday - Friday 7:30 AM - 4:00 PM

Hourly pay range: $24 - $27

Benefits:

Health & Wellness

• Comprehensive Medical, Dental, and Vision coverage

• Wellness programs

• Eligible for medical coverage starting Day 1

Time Off

• Paid Time Off (PTO)

• Company-paid holidays

• Choice holidays

Financial Well-Being

• Flexible Spending Account (FSA) and Health Savings Account (HSA)

• Commuter benefits

• 401(k) retirement plan

• Tuition assistance

• Employee Stock Purchase Plan discount

What we're looking for

Education:

• High school diploma or GED required

• Bachelor's degree preferred

Experience:

• Minimum 2 years in customer service, inventory replenishment, or material handling

• 1-2 years of experience in a laboratory environment or familiarity with lab processes and procedures preferred

• 1-2 years of experience

Technical Skills:

• Proficient in Microsoft Office and comfortable using computers

• Experience with Microsoft Teams preferred

• Knowledge of SAP, Oracle, Power BI, and other inventory management systems

Additional Requirements:

• Ability to lift up to 25 lbs

• Previous experience in a GMP-regulated facility strongly desired

• Strong communication skills

How you will thrive and create an impact

Avantor's Advanced Laboratory Services team is a crucial part of the Avantor Services group serving over 500 customers in biopharma, pharmaceutical, educational, industrial, and high-tech industries with customizable, flexible solutions and end-to-end laboratory operations support. In this role you will:

Glassware Washing & Laboratory Support

• Perform routine washing, drying, and sterilization of laboratory glassware following established SOPs.

• Inspect glassware for cleanliness, damage, or wear and remove items that do not meet quality standards.

• Organize, label, and restock clean glassware to designated laboratory areas to ensure uninterrupted workflow.

• Maintain cleanliness of washing stations, autoclaves, drying ovens, and related equipment.

• Track inventory of glassware and notify appropriate personnel of low stock or replacement needs.

PPE Cleaning & Maintenance

• Collect, clean, and sanitize personal protective equipment (PPE) according to facility hygiene and safety requirements.

• Inspect PPE for damage, contamination, or wear and escalate issues requiring replacement.

• Ensure all cleaned PPE meets quality and safety standards prior to restocking or redistribution.

PPE Restocking & Inventory

• Monitor PPE inventory levels and restock gowns, gloves, eyewear, lab coats, and other protective items across designated labs or workstations.

• Maintain accurate inventory logs and communicate supply needs to procurement or site leads.

• Ensure PPE stations remain organized, labeled, and accessible to laboratory personnel.

Buffer Preparation

• Assist with preparing laboratory buffers and solutions following established formulations and SOPs.

• Measure, mix, and label chemical components clearly and accurately.

• Perform pH adjustments, verify concentrations, and maintain batch documentation.

• Ensure proper storage and handling of prepared buffers to maintain stability and compliance.

Chemical Management

• Support safe handling, storage, and organization of laboratory chemicals.

• Track chemical inventory and assist with ordering, receiving, and restocking materials.

• Maintain up-to-date SDS files and support chemical safety compliance.

• Assist with waste collection, labeling, and disposal following environmental and regulatory guidelines.

Disclaimer:
The above statements are intended to describe the general nature and level of work being performed by employees assigned to this classification. They are not intended to be construed as an exhaustive list of all responsibilities, duties and skills required of employees assigned to this position. Avantor is proud to be an equal opportunity employer.

Why Avantor?

Dare to go further in your career. Join our global team of 14,000+ associates whose passion for discovery and determination to overcome challenges relentlessly advances life-changing science.

The work we do changes people's lives for the better. It brings new patient treatments and therapies to market, giving a cancer survivor the chance to walk his daughter down the aisle. It enables medical devices that help a little boy hear his mom's voice for the first time. Outcomes such as these create unlimited opportunities for you to contribute your talents, learn new skills and grow your career at Avantor.

We are committed to helping you on this journey through our diverse, equitable and inclusive culture which includes learning experiences to support your career growth and success. At Avantor, dare to go further and see how the impact of your contributions set science in motion to create a better world. Apply today!

EEO Statement:

We are an Equal Employment/Affirmative Action employer and VEVRAA Federal Contractor. We do not discriminate in hiring on the basis of sex, gender identity, sexual orientation, race, color, religious creed, national origin, physical or mental disability, protected Veteran status, or any other characteristic protected by federal, state/province, or local law.

If you need a reasonable accommodation for any part of the employment process, please contact us by email at let us know the nature of your request and your contact information. Requests for accommodation will be considered on a case-by-case basis. Please note that only inquiries concerning a request for reasonable accommodation will be responded to from this email address.

For more information about equal employment opportunity protections, please view the Know Your Rights poster.

3rd Party Non-Solicitation Policy:

By submitting candidates without having been formally assigned on and contracted for a specific job requisition by Avantor, or by failing to comply with the Avantor recruitment process, you forfeit any fee on the submitted candidates, regardless of your usual terms and conditions. Avantor works with a preferred supplier list and will take the initiative to engage with recruitment agencies based on its needs and will not be accepting any form of solicitation.

Our Crew Members create a warm and friendly shopping experience in our stores. We answer questions, offer suggestions, and ensure our customers know they are welcomed and cared for. We entertain customers and make grocery shopping an exciting adventure.

Some responsibilities may include:

• Working on teams to accomplish goals
• Operating the cash register in a fun and efficient manner
• Bagging groceries with care
• Stocking shelves
• Creating signage to inform and delight customers
• Helping customers find their favorite products

You'll learn a lot. You're not stuck doing one task here. Each Crew Member contributes to creating a WOW customer experience by participating in all aspects of the job.

If you have experience in art including penmanship, working with chalk, and large signage, that's a plus.

If you have a passion for people and a fervor for food, we'd love to meet you. We can teach you the rest.

Stores have the greatest need for people that can work evenings and weekends.

Trader Joe's is an equal-opportunity employer and is committed to hiring a diverse Crew.

Location: Framingham, MA

Practice Area: Family Law

We are a small, established family law firm in Framingham, Massachusetts, seeking an experienced attorney to join our team.

Responsibilities

• Represent clients in Probate & Family Court matters including divorce, custody, child support, alimony, modifications, and contempt actions.
• Draft pleadings, discovery, and agreements; attend hearings and mediation/conciliation.
• Conduct legal research and prepare memoranda.
• Negotiate settlements and participate in mediation/conciliation sessions.
• Attend motion hearings, pretrial/status conferences, and trials.
• Provide compassionate, timely communication and support to clients.
• Collaborate with the firm's attorneys and paralegals on case strategy.

Job Requirements

• Juris Doctor (JD) and admission to the Massachusetts Bar in good standing.
• Minimum of 3 years of experience in Massachusetts family law litigation required.
• Strong drafting, research, and oral advocacy skills.
• Ability to manage cases independently while contributing to a team.
• Empathetic, client-focused approach.

Compensation

• $120,000+ commensurate with experience.
• Bonus Potential.
• Health, Dental, and Vision Insurance.
• Retirement plan with employer match.

Our client, a boutique real estate law firm in Framingham, is seeking a Residential Real Estate Paralegal to join their team.

In this role, you’ll be assisting attorneys and team with residential and commercial closings from start to finish—opening new files, ordering title exams and municipal documents, preparing title commitments, and ensuring every detail is in place for a smooth and timely closing. You’ll also manage post-closing tasks and maintain excellent communication with clients, lenders, and attorneys throughout the process.

The ideal candidate is organized, proactive, and thrives in a high-volume setting.

Excellent compensation and benefits.

Please apply to Bridgeline Solutions today!

*2nd shift, 3-11pm*

Job Summary

The Manufacturing Supervisor provides hands-on leadership of second shift GMP manufacturing operations for microbiome Live Biologic Products. This role supervises four contract associates and ensures safe, compliant, and efficient execution of fermentation, harvest, lyophilization, media/buffer preparation, packaging, and suite readiness activities. The Supervisor serves as the primary on-site manufacturing leader during second shift and actively supports floor operations.

Responsibilities

• Supervise second shift GMP manufacturing activities, including fermentation and downstream processing.
• Lead and support four contract manufacturing associates; assign tasks and provide coaching.
• Ensure production suites, equipment, and materials are ready and compliant.
• Enforce cGMP, safety, and quality standards.
• Review batch records and documentation for accuracy and completeness.
• Execute shift schedules to meet production timelines.
• Escalate and support resolution of manufacturing issues, deviations, CAPAs, and change controls.
• Support new processes, SOP implementation, and technology transfers.
• Provide clear shift handovers and communicate production status and risks.

Qualifications

• Bachelor’s degree in Biology, Biochemistry, Engineering, or related field preferred.
• 3–6 years of GMP manufacturing experience; prior supervisory or lead experience preferred.
• Experience with fermentation, microbial processing, aseptic techniques, or lyophilization preferred.
• Strong knowledge of cGMP regulations and documentation practices.
• Experience reviewing batch records and supporting deviation management.

Position Summary:

The Associate Director, Quality Control will be responsible for providing strategic, scientific, and operational leadership for the development, qualification, validation, and lifecycle management of analytical methods supporting Upstream Bio’s lead program verekitug. This role will manage and execute GMP quality control (QC) activities directly related to batch release for clinical trial material supply. The leader in this role must assure that quality controls for investigational new drugs (investigational medicinal products) meet all quality requirements, regulatory standards, and meet continuous clinical supply and delivery expectations. The Associate Director will report to Senior Director of Analytical and serve as a key partner to Quality, CMC, Regulatory, and cross-functional teams. This individual will provide technical guidance and business acumen to ensure execution of analytical activities for late-stage programs through BLA/MAA submission, approval, and commercial launch.

Key Responsibilities:

• Author, review and approve analytical method procedures/SOPs
• Author, review and approve analytical method transfer/qualification/validation protocols and reports
• Manage external CDMOs and CROs to execute Development and GMP release and stability testing of Drug Substance and Drug Product in a compliant-manner
• Establish and manage reference standard and critical reagent programs
• Participate in the laboratory quality system activities such as internal audits, writing standard operating procedures, and documentation review.
• Perform data verification and audits in order to ensure accuracy of data and analytical processes.
• Ensure compliance with company policies and SOPs as well as global health authority guidelines.
• Create, analyze, verify, and approve QC data such as method validation, release and stability, results, reports, and Certificates of Analysis (COAs).
• Generate, review, and revise specifications, SOPs, and other QC laboratory and testing documentation.
• Lead Out-of-Specification (OOS), Out-of-Trend (OOT), and Deviation investigations related to the QC laboratory and ensure effective corrective and preventive actions (CAPAs) are implemented.

Qualifications:

• Experience in stability study performance/evaluation and/or knowledge/familiarity with USP/compendial testing is helpful.
• Excellent verbal and written communication/interpersonal skills, problem-solving skills, organizational skills, and the ability to work in a diverse team environment are essential.
• Proficiency with Microsoft software (Word / EXCEL / PowerPoint), Stability software and statistical analysis/trending to support shelf life and labeling is expected.

Knowledge and skills (general and technical) preferred:

• Broad background, strong comprehension, and demonstrated skills in analytical methods development/validation/transfer/similar, reference standards characterization/structural elucidation, and unknown identification.

Education level and/or relevant experience required:

• Bachelor’s degree in a scientific or allied health field (or equivalent degree) and 10+ years of demonstrated success in leading cross-functional teams and managing projects along with 7+ years relevant analytical experience in a cGMP-compliant pharmaceutical laboratory environment. Any ASQ or other certifications is a plus.

About Upstream Bio:

Upstream Bio is a public company based in Waltham, MA. We are developing verekitug, the only known antagonist currently in development that targets the receptor for Thymic Stromal Lymphopoietin (TSLP). We have advanced this highly potent monoclonal antibody into separate Phase 2 trials for the treatment of severe asthma and chronic rhinosinusitis with nasal polyps (CRSwNP) and plan to initiate development in chronic obstructive pulmonary disease (COPD). Our experienced team is committed to maximizing verekitug’s unique attributes to address the substantial unmet needs for patients underserved by today’s standard of care. Learn more about us at .

Compensation

Target Salary Range: $176,400 - $215,600

*Base Compensation for this role will depend on a number of factors including a candidate’s qualifications, skills, competencies, and experience. Base pay is only one component of the company’s total rewards package. All regular employees are also eligible for the corporate bonus program or the incentive compensation program (if applicable), as well as equity. Additional benefits include health care, vision, dental, retirement, PTO, etc.

Medical Device Manufacturing Engineer Co-Op/Intern

On-site in Seaport, Massachusetts May-August (extension possible)

Amplitude Vascular Systems (AVS), an early-stage medical device company focused on safely and effectively treating severely calcified arterial disease, is seeking a Manufacturing Engineer-Co-Op to support our Operations team. This individual will work in a cross-functional role (Quality/Manufacturing/R&D) supporting the manufacturing of devices and associated instruments and technologies.

Key Responsibilities:

• Willing to work for cross functional teams (Operations, R&D and Quality & Regulatory.)
• Creating and modifying designs/drawings utilizing SolidWorks
• Testing prototype devices for functionality
• Supporting manufacturing with failure analysis
• Working in the lab, summarizing data, performing tests, and writing technical reports
• Participating and collaborating in team meetings and updates.
• Experience in Microsoft Word, Excel, and PowerPoint is essential
• Ability to work independently as well as take direction and complete tasks with or without help or supervision.

.Qualifications:

• In pursuit of Bachelor's degree in Mechanical, Industrial, Manufacturing, Electrical, or Biomedical Engineering. In Junior year or above.
• Self-motivated with an interest in medical devices
• 3-D modeling skills (NX Unigraphics & Solidworks Preferred)
• Experience using hand tools and performing mechanical testing
• Proven problem-solving capabilities
• Ability to communicate technical information
• Previous co-op completed in manufacturing at a medical device demonstrating skillsets listed above preferred.
• A minimum G.P.A. of 3.0
• Available to work full-time (40 hrs/week) May-August 2026
• This is an onsite position located in Waltham, MA.

AVS is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, age, national origin, or protected veteran status and will not be discriminated against on the basis of disability.