Jobs in Cambridge Massachusetts

1,981 positions found — Page 6

Pricing Actuary
✦ New
Salary not disclosed
Boston, MA 14 hours ago
General

Job Title: Pricing Actuary

Division: Finance - Actuarial

Reports To: Lead Pricing Actuary - Cyber & Executive Risks

Key Relationships: Underwriters and business managers, Beazley actuaries, Claims managers, Data Management and Ceded Reinsurance teams, regulators, external actuaries, brokers.

Job Summary: Actuarial pricing for the Cyber Risks Division and the Executive Risks classes (within the Specialty Risks Division) at Beazley

Key Responsibilities:

Technical

  • Provide pricing support to the Cyber & Executive Risks underwriting teams at Beazley; pricing support includes (as required):
  • Developing pricing tools that support the estimation of price adequacy and rate change
  • Performing portfolio and transactional pricing analyses
  • Performing segmental and trend analyses
  • Performance monitoring (e.g. rate change and price adequacy metrics)
  • Develop, maintain and review pricing models to the required standards
  • Contribute effectively to the production of the relevant reports required for any key committees where required.
  • Provide training to underwriters in pricing; this includes technical pricing and rate change requirements
  • Understand and support the underwriting controls related to pricing and relevant regulatory principles
  • Understand and apply the pricing quality assurance process
  • Assist in other projects undertaken by the actuarial team e.g. liability transfer valuations and business planning analyses
  • Operate as an effective team member by supporting colleagues and contributing in the delivery and achievement of overall team and business objectives
  • Build your technical pricing skills and experience
  • Provide support and mentoring to the junior members of the team
  • Keep abreast of industry best practice, new initiatives and changes in regulatory requirements
  • Build and maintain constructive working arrangements with those groups identified as being key to your role
  • Work with the underwriters, exposure management, claims managers, Data Management and Ceded Reinsurance to ensure the quality and appropriateness of the data used for pricing; ensure the necessary data is captured from pricing tools to enhance future pricing capabilities
  • Maintain pricing model documentation with required frequency, obtaining the appropriate managerial sign-offs
  • Identify opportunities and contribute to delivering improvements in the pricing processes and methodologies
  • Undertake professional, technical and career development training (delivered internally and externally); this includes pursuing the actuarial qualification where applicable

General

It is important that within all your interactions both internally and externally you adhere to Beazley's core values - Being Bold, Striving for Better, and Doing the Right Thing - as they contribute to an internal environment of teamwork and promote a positive brand image and experience to our external customers. We also expect Beazley employees to:

  • Comply with Beazley procedures, policies and regulations including the code of conduct which incorporates the PRA and FCA Conduct.
  • Undertake training on Beazley policies and procedures as delivered by your line manager, the People & Sustainability or assurance teams (compliance, risk, internal audit) either directly, via e-learning or the learning management system.
  • Display business ethics that uphold the interests of all our customers
  • Ensure all interactions with customers are focused on delivering a fair outcome, including having the right products for their needs.
  • Comply with any specific responsibilities necessary for your role as outlined by your line manager, the People & Sustainability or assurance teams (compliance, risk, internal audit) and ensure you keep up to date with developments in these areas. This may include, amongst others, Beazley's underwriting control standards, Beazley's claims control standards, other Beazley standards and customer relationship management.
  • Carry out additional responsibilities as individually notified, either through your objectives or through the learning management system. These may include membership of any Beazley committees or working groups.

Personal Specification:

Essential Criteria

  • Actuarial qualification
  • Pricing experience; with specialty (re)-insurance market knowledge desirable
  • Firm grasp of actuarial / statistical techniques used in pricing
  • Understanding of reinsurance and capital with application to pricing

Education and Qualifications

  • University degree in Mathematics or related field

Skills and Abilities

  • General commercial and financial knowledge
  • Competent user of MS Excel; VBA, Access, Python, SQL and R skills desirable
  • Strong analytical skills with attention to detail; accurate and numerate
  • Able to communicate effectively both verbally and in writing
  • Team worker as well as able to work on own initiative
  • Ability to manage time, meet deadlines and prioritise

Aptitude and Disposition

  • Outcome focused, self-motivated, flexible and enthusiastic
  • Professional approach to successfully interact with team members, internal and external stakeholders

Competencies

  • Achievement and solution focused
  • Analytical
  • Information seeking
  • Stakeholder focus
  • Using initiative
  • Having integrity
  • Taking responsibility
  • Attention to detail

Who We Are:

Beazley is a specialist insurance company with over 30 years' experience helping people, communities and businesses to manage risk all around the world. Our mission is to inspire our clients and people with the confidence and freedom to explore, create and build - to enable businesses to thrive. Our clients want to live and work freely and fully, knowing they are benefitting from the most advanced thinking in the insurance market. Our goal is to become the highest performing sustainable specialist insurer.

Our products are wide ranging, from cyber & tech insurance to marine, healthcare, financial institutions and contingency; covering risks such as the weather, film production or protection from deadly weapons.

Our Culture

We have a wonderful mix of cultures, experiences, and backgrounds at Beazley with over 2,000 of us working around the world.Employee's diversity,experience and passion allow us to keep innovating and moving forward, delivering the best. We are proud of our family-feel culture at Beazley that empowers our staff to work from when and where they want, in an adult environment that is big on collaboration, diversity of thought and personal accountability. Our three core values inspire the way we work and how we treat our people and customers.

  • Be bold
  • Strive for better
  • Do the right thing

Upholding these values every day has enabled us to become an innovative and responsive organization in touch with the changing world around us - our ambitious inclusion & diversity and sustainability targets are testament to this.

We are a flexible and innovative employer offering a friendly, collaborative, and inclusive working environment. We actively encourage and expect applications from all backgrounds. Our commitment to fostering a supportive and dynamic workplace ensures that every employee can thrive and contribute to our collective success.

Explore a variety of networks to assist with professional and/or personal development. Our Employee. Networks include:

  • Beazley RACE - Including, understanding and celebrating People of Colour
  • Beazley SHE - Successful, High potential, Empowered women in insurance
  • Beazley Proud - Our global LGBTQ+ community
  • Beazley Wellbeing - Supporting employees with their mental wellbeing
  • Beazley Families - Supporting families and parents-to-be

We encourage internal career progression at Beazley, giving you all the tools you need to drive your own career here, such as:

  • Internal Pathways (helping you grow into an underwriting role)
  • iLearn (our own learning & development platform)
  • LinkedIn Learning
  • Mentorship program
  • External qualification sponsorship
  • Continuing education and tuition reimbursement
  • Secondment assignments

The Rewards UK

  • The opportunity to connect and build long-lasting professional relationships while advancing your career with a growing, global organization.
  • Attractive base compensation and discretionary performance related annual bonus
  • Private medical insurance coverage for both you and your dependents
  • Company paid life assurance and long term disability insurance
  • Pension with 10% employer contribution, plus a further matched contribution up to 2.5%
  • 25 days of annual leave (prorated for 1st calendar year of employment), plus public holidays, with the ability to flex the religious bank holidays to suit your religious beliefs, subject to approval. Additional annual leave purchase is also available up to a maximum of five additional days per year.
  • Up to 2.5 days matched paid leave for volunteering at a charity of your choice and 5 days paid leave to provide or arrange care for a dependent with a long term care need annually
Not Specified
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Director, AI/ML Strategy and Technology Enablement
✦ New
Salary not disclosed
Boston, Massachusetts 14 hours ago

By clicking the "Apply" button, I understand that my employment application process with Takeda will commence and that the information I provide in my application will be processed in line with Takeda's Privacy Notice and Terms of Use. I further attest that all information I submit in my employment application is true to the best of my knowledge.

Job Description

Role Summary

Lead the strategy, platform build-out, and adoption of AI/ML across Research for global digital transformation effort, making AI agents, models, and tools a daily, accessible part of wet‐lab and dry‐lab scientists' workflows. Translate AF priorities into a practical, compliant AI services layer—data foundations, MLOps, agentic assistants, model governance, and change enablement—that shortens time from experiment to insight and elevates decision quality across discovery programs.

Objectives / Purpose

  • Define and execute a multi‐year AI/ML roadmap aligned to Research use cases and KPIs.
  • Establish an AI‐ready data foundation (FAIR-by-design) and scientist‐facing AI tools embedded in ELN/LIMS/instrument workflows.
  • Institutionalize Responsible AI & GxP-aware governance for production models.
  • Drive adoption through super-user networks, training, and change management to achieve measurable value and ROI.

Scope / Impact

Global Research scope with cross‐site collaboration (US/EU/JP). Direct impact on data-to-decision latency, assay/analysis reproducibility, and portfolio productivity. Partner with operations, Computational Sciences & Data Strategy, IT, function leads, and platform teams to deliver outcomes at scale.

Accountabilities

Strategy & Roadmap

  • Own Research's AI/ML strategy and sequencing (MVP → scale) across wet‐lab dry‐lab integration and self‐service tools.
  • Align priorities with Research's KPIs and portfolio goals; establish and monitor achievement of success criteria and milestones.

Platform, Data & Integration

  • Guide the development of AI‐ready data foundations (provenance, metadata/ontologies, harmonization) across ELN/LIMS, instruments, imaging, and omics.
  • Integrate platforms (e.g., ELN, SDMS & AI Cloud) to liberate, contextualize, and operationalize lab data for AI/ML.
  • Stand up modern MLOps (CI/CD, registries, experiment tracking, monitoring) and secure service/APIs embedded in workflows.

Agentic AI & Productization

  • Design self-service and user-friendly processes for deployment of AI agents for scientists (literature triage, protocol assist, data QC, analysis pipelines, code helpers).
  • Guide engineering efforts to deliver production models (e.g., sequence/structure prediction, assay QC, outlier detection, multimodal analytics).

Adoption & Change Enablement

  • Lead adoption via super‐user networks, training, and communications; co‐own readiness plans with NCSP.
  • Work with Change Management leads to publish playbooks and guardrails enabling self‐service AI workflows for scientists.

Governance, Risk & Compliance

  • Define and Implement Responsible AI and risk‐based governance (ALCOA+, validation mindset, audit trails, XAI, privacy/PII controls).

Impact & Reporting

  • Own measurable impact (adoption, latency, reproducibility, ROI) and provide transparent reporting to R&D leadership and key stakeholders.

Qualifications

Required

PhD degree in a scientific discipline with 10+ years experience , or

MS with 16+ years experience, or BS with 18+ years experience (preferably in Advanced degree in Computer Science, AI/ML, Computational Biology/Chemistry, Bioinformatics, or related; or equivalent industry experience.)

Proven MLOps platform build and delivery of scientist‐facing AI tools embedded in ELN/LIMS/instrument workflows.

Expertise in FAIR data, scientific data models/ontologies, and integration across wet‐lab instruments, imaging, and omics.

Experience with Responsible AI and GxP‐adjacent validation/governance in pharma/biotech R&D.

Strong stakeholder management; ability to translate complex science/data into usable AI for end users.

Preferred

  • Experience working in wet-labs and knowledge of Research and Development workflows and processes in either the biologics and/or small molecule fields
  • Agentic AI systems and LLMs for scientific contexts; multimodal ML (text/images/sequences/numerical).
  • Knowledge of Research/Pharma Sci common data models and cloud analytics/HPC integrations.

Takeda Compensation and Benefits Summary

We understand compensation is an important factor as you consider the next step in your career. We are committed to equitable pay for all employees, and we strive to be more transparent with our pay practices.

For Location:

Boston, MA

U.S. Base Salary Range:

$174,500.00 - $274,230.00
The estimated salary range reflects an anticipated range for this position. The actual base salary offered may depend on a variety of factors, including the qualifications of the individual applicant for the position, years of relevant experience, specific and unique skills, level of education attained, certifications or other professional licenses held, and the location in which the applicant lives and/or from which they will be performing the job. The actual base salary offered will be in accordance with state or local minimum wage requirements for the job location.

U.S. based employees may be eligible for short-term and/ or long-term incentives. U.S. based employees may be eligible to participate in medical, dental, vision insurance, a 401(k) plan and company match, short-term and long-term disability coverage, basic life insurance, a tuition reimbursement program, paid volunteer time off, company holidays, and well-being benefits, among others. U.S. based employees are also eligible to receive, per calendar year, up to 80 hours of sick time, and new hires are eligible to accrue up to 120 hours of paid vacation.

EEO Statement

Takeda is proud in its commitment to creating a diverse workforce and providing equal employment opportunities to all employees and applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, gender expression, parental status, national origin, age, disability, citizenship status, genetic information or characteristics, marital status, status as a Vietnam era veteran, special disabled veteran, or other protected veteran in accordance with applicable federal, state and local laws, and any other characteristic protected by law.

Locations

Boston, MA

Worker Type

Employee

Worker Sub-Type

Regular

Time Type

Full time

Job Exempt

Yes It is unlawful in Massachusetts to require or administer a lie detector test as a condition of employment or continued employment. An employer who violates this law shall be subject to criminal penalties and civil liability.
Not Specified
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Travel Nurse RN - Oncology - $3,143 per week in Needham, MA
✦ New
Salary not disclosed

Registered Nurse (RN) | Oncology Location: Needham, MA Agency: Prime Staffing Pay: $3,143 per week Shift Information: Days - 5 days x 8 hours Contract Duration: 13 Weeks Start Date: 4/6/2026

About the Position

TravelNurseSource is working with Prime Staffing to find a qualified Oncology RN in Needham, Massachusetts, 02492!

About the Position
Specialty: RN – Oncology
Experience: 1–2+ years in oncology or infusion preferred
License: Active State or Compact RN License
Certifications: BLS – AHA; ONS Chemotherapy/Biotherapy Certification preferred
Must-Have: Experience with central lines, chemotherapy administration, and symptom management


Description: The Oncology RN provides compassionate care to patients undergoing cancer treatment. Responsibilities include chemotherapy and medication administration, monitoring for adverse reactions, patient education, and emotional support. The RN collaborates with oncologists and multidisciplinary teams to deliver personalized care plans and manage complex symptoms.

Requirements

Required for Onboarding:

  • Active RN License
  • BLS

About Prime Staffing

At Prime Staffing, we understand the importance of finding the perfect fit for both our clients and candidates. Prime Staffing utilizes a unique matchmaking approach, providing the most qualified contingent staffing to our clients, and the most competitive contracts to our workforce. Our experienced team takes the time to get to know both our clients and candidates, their needs, and preferences, to ensure that each placement is a success.

We offer a wide range of staffing services including temporary, temp-to-perm, and direct hire placements. Our extensive network of qualified candidates includes nurses, allied healthcare professionals, corporate support professionals and executives.

Requirements

Required for Onboarding

  • BLS

29515697EXPPLAT

Not Specified
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Research Senior Scientist AI/ML Orchestration and Operationalization
✦ New
🏢 Takeda Pharmaceutical Company Ltd
Salary not disclosed
Boston, Massachusetts 14 hours ago

By clicking the "Apply" button, I understand that my employment application process with Takeda will commence and that the information I provide in my application will be processed in line with Takeda's Privacy Notice and Terms of Use. I further attest that all information I submit in my employment application is true to the best of my knowledge.

Job Description

At Takeda, we are a forward-looking, world-class R&D organization that unlocks innovation and delivers transformative therapies to patients. By focusing R&D efforts on three therapeutic areas and other targeted investments, we push the boundaries of what is possible to bring life-changing therapies to patients worldwide.

The AI/ML organization at Takeda is building a team to transform how medicines are discovered. Our goal is to apply AI and machine learning across the entire drug discovery process, not just isolated steps, but as an integrated approach from target identification through development. This requires discernment: knowing which models and methods fit each problem, and the creativity to adapt when they don't. We work with foundational models, generative approaches, and autonomous systems, but the tools only matter when paired with people who understand the science deeply enough to use them well. Our team brings together computational scientists, biologists, engineers, and drug hunters. If you want to contribute your expertise to hard problems alongside colleagues with different perspectives, and help shape how AI delivers real impact in drug discovery, we'd like to hear from you

We are seeking a Senior Scientist to lead the design and implementation of AI orchestration systems within the AI/ML Foundation team. This role combines expertise in agentic AI systems, data engineering, and software architecture to build the infrastructure that enables seamless coordination of AI capabilities across Computational Sciences and Global Research. You will be responsible for creating intelligent orchestration layers that connect diverse AI models, data pipelines, and computational resources to accelerate drug discovery across all therapeutic modalities. The ideal candidate brings strong engineering fundamentals with experience in distributed systems and a passion for building scalable AI platforms.

Accountabilities:

  • Design and implement AI orchestration frameworks that integrate agentic systems, data pipelines, and model serving infrastructure to enable coordinated multi-model workflows.
  • Build scalable orchestration layers connecting predictive models, generative models, and foundation models with experimental data sources for end-to-end workflow automation.
  • Develop data engineering solutions including data ingestion pipelines, transformation workflows, feature stores, and model serving infrastructure supporting discovery across modalities.
  • Create intelligent orchestration systems that coordinate agentic AI components for autonomous task decomposition, tool selection, and execution across scientific domains.
  • Establish monitoring, observability, and governance frameworks ensuring reliability, reproducibility, and transparent decision-making across AI systems.
  • Partner with computational scientists, data engineers, and research teams to ensure orchestration infrastructure meets the needs of diverse discovery workflows.
  • Stay current with advances in agentic AI, workflow orchestration, and distributed systems; evaluate and integrate emerging technologies.

Education & Requirements:

  • PhD in Computer Science, Data Engineering, Computational Science, or related field with 2+ years relevant experience, OR MS with 6+ years relevant experience.
  • Strong software engineering skills with proficiency in Python and experience with distributed systems and cloud infrastructure (AWS, GCP).
  • Experience with workflow orchestration frameworks (Airflow, Prefect, Dagster, or similar) and data pipeline development.
  • Familiarity with agentic AI frameworks (LangChain, AutoGen, or similar) and LLM integration patterns.
  • Experience with containerization (Docker, Kubernetes) and microservices architecture.
  • Strong problem-solving skills and ability to work across teams in a fast-paced R&D environment.

Preferred:

  • Experience building AI/ML platforms or infrastructure in pharmaceutical or life sciences settings.
  • Familiarity with scientific computing workflows and computational chemistry/biology tools.
  • Experience with model serving frameworks (TorchServe, Triton, BentoML) and feature stores.
  • Knowledge of monitoring and observability tools (Prometheus, Grafana, MLflow).
  • Experience with event-driven architectures

Additional Competencies Common in Strong Candidates

  • Ability to lead cross-functional initiatives and mentor junior scientists.
  • Experience in translating computational insights into experimental strategies.
  • Strong publication record or demonstrated thought leadership in AI for biology and molecular design.
  • Comfort working in fast-paced, innovation-driven environments with evolving priorities.

ADDITIONAL INFORMATION

  • The position will be based in Cambridge, MA

Takeda Compensation and Benefits Summary

We understand compensation is an important factor as you consider the next step in your career. We are committed to equitable pay for all employees, and we strive to be more transparent with our pay practices.

For Location:

Boston, MA

U.S. Base Salary Range:

$137,000.00 - $215,270.00
The estimated salary range reflects an anticipated range for this position. The actual base salary offered may depend on a variety of factors, including the qualifications of the individual applicant for the position, years of relevant experience, specific and unique skills, level of education attained, certifications or other professional licenses held, and the location in which the applicant lives and/or from which they will be performing the job. The actual base salary offered will be in accordance with state or local minimum wage requirements for the job location.

U.S. based employees may be eligible for short-term and/ or long-term incentives. U.S. based employees may be eligible to participate in medical, dental, vision insurance, a 401(k) plan and company match, short-term and long-term disability coverage, basic life insurance, a tuition reimbursement program, paid volunteer time off, company holidays, and well-being benefits, among others. U.S. based employees are also eligible to receive, per calendar year, up to 80 hours of sick time, and new hires are eligible to accrue up to 120 hours of paid vacation.

EEO Statement

Takeda is proud in its commitment to creating a diverse workforce and providing equal employment opportunities to all employees and applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, gender expression, parental status, national origin, age, disability, citizenship status, genetic information or characteristics, marital status, status as a Vietnam era veteran, special disabled veteran, or other protected veteran in accordance with applicable federal, state and local laws, and any other characteristic protected by law.

Locations

Boston, MA

Worker Type

Employee

Worker Sub-Type

Regular

Time Type

Full time

Job Exempt

Yes It is unlawful in Massachusetts to require or administer a lie detector test as a condition of employment or continued employment. An employer who violates this law shall be subject to criminal penalties and civil liability.
Not Specified
View & Apply
Research Senior Scientist AI/ML - Agentic Systems
✦ New
🏢 Takeda Pharmaceutical Company Ltd
Salary not disclosed
Boston, Massachusetts 14 hours ago

By clicking the "Apply" button, I understand that my employment application process with Takeda will commence and that the information I provide in my application will be processed in line with Takeda's Privacy Notice and Terms of Use. I further attest that all information I submit in my employment application is true to the best of my knowledge.

Job Description

At Takeda, we are a forward-looking, world-class R&D organization that unlocks innovation and delivers transformative therapies to patients. By focusing R&D efforts on three therapeutic areas and other targeted investments, we push the boundaries of what is possible to bring life-changing therapies to patients worldwide.

The AI/ML organization at Takeda is building a team to transform how medicines are discovered. Our goal is to apply AI and machine learning across the entire drug discovery process, not just isolated steps, but as an integrated approach from target identification through development. This requires discernment: knowing which models and methods fit each problem, and the creativity to adapt when they don't. We work with foundational models, generative approaches, and autonomous systems, but the tools only matter when paired with people who understand the science deeply enough to use them well. Our team brings together computational scientists, biologists, engineers, and drug hunters. If you want to contribute your expertise to hard problems alongside colleagues with different perspectives and help shape how AI delivers real impact in drug discovery, we'd like to hear from you.

Position Overview

We are seeking Senior Scientists to develop agentic AI systems that transform how drug discovery research is conducted. As part of the AI/ML Foundation team, you will build autonomous AI agents capable of reasoning, planning, and executing complex scientific workflows—from literature synthesis and target identification to experimental design and data analysis. This role requires a unique combination of expertise in large language models, agentic frameworks, and understanding of drug discovery processes. You will translate standard research workflows into agentic frameworks, develop new agent skills, and deploy systems that augment scientist productivity across Computational Sciences and Global Research.

Accountabilities:

  • Develop agentic AI systems for drug discovery applications including target-disease association, automated literature search and synthesis, hypothesis generation, and intelligent design of experiments.
  • Translate standard research workflows into agentic frameworks—decomposing complex scientific processes into autonomous agent tasks that can reason, plan, execute tools, and iterate based on results.
  • Design and implement new agent skills (tools, functions, APIs) that extend agentic capabilities to specialized scientific domains including molecular design, property prediction, assay planning, and data analysis.
  • Build agentic systems that integrate with foundation models and external knowledge sources for autonomous hypothesis generation, evidence retrieval, and scientific reasoning.
  • Develop retrieval-augmented generation (RAG) pipelines connecting agents to internal and external scientific literature, databases, and experimental results.
  • Partner with research scientists to understand workflow needs, validate agent outputs, and iterate on system design to ensure scientific rigor and utility.
  • Stay current with advances in agentic AI, LLM applications, and scientific automation; contribute to internal knowledge sharing and external publications.

Educational & Requirements:

  • PhD in Computer Science, Computational Biology, Bioinformatics, or related field with 2+ years relevant experience, OR MS with 6+ years relevant experience.
  • Strong experience with large language models (GPT, Claude, Llama) and their application to complex reasoning tasks.
  • Proficiency in Python and experience with agentic AI frameworks (LangChain, AutoGen, CrewAI, or similar).
  • Experience building RAG systems including vector databases, embedding models, and retrieval pipelines.
  • Understanding of drug discovery processes and scientific research workflows.
  • Strong problem-solving skills and ability to translate complex scientific processes into computational workflows.

Preferred:

  • Experience in pharmaceutical or biotech R&D environments.
  • Background in biology, chemistry, or disease biology.
  • Experience with reinforcement learning or planning algorithms for agent decision-making.
  • Familiarity with scientific databases (PubMed, UniProt, ChEMBL) and APIs.
  • Experience deploying AI systems in production environments.
  • Track record of publications or presentations on LLM ap

Additional Competencies Common in Strong Candidates

  • Ability to lead cross-functional initiatives and mentor junior scientists.
  • Experience in translating computational insights into experimental strategies.
  • Strong publication record or demonstrated thought leadership in AI for biology and molecular design.
  • Comfort working in fast-paced, innovation-driven environments with evolving priorities.

ADDITIONAL INFORMATION

  • The position will be based in Cambridge, MA

Takeda Compensation and Benefits Summary

We understand compensation is an important factor as you consider the next step in your career. We are committed to equitable pay for all employees, and we strive to be more transparent with our pay practices.

For Location:

Boston, MA

U.S. Base Salary Range:

$137,000.00 - $215,270.00
The estimated salary range reflects an anticipated range for this position. The actual base salary offered may depend on a variety of factors, including the qualifications of the individual applicant for the position, years of relevant experience, specific and unique skills, level of education attained, certifications or other professional licenses held, and the location in which the applicant lives and/or from which they will be performing the job. The actual base salary offered will be in accordance with state or local minimum wage requirements for the job location.

U.S. based employees may be eligible for short-term and/ or long-term incentives. U.S. based employees may be eligible to participate in medical, dental, vision insurance, a 401(k) plan and company match, short-term and long-term disability coverage, basic life insurance, a tuition reimbursement program, paid volunteer time off, company holidays, and well-being benefits, among others. U.S. based employees are also eligible to receive, per calendar year, up to 80 hours of sick time, and new hires are eligible to accrue up to 120 hours of paid vacation.

EEO Statement

Takeda is proud in its commitment to creating a diverse workforce and providing equal employment opportunities to all employees and applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, gender expression, parental status, national origin, age, disability, citizenship status, genetic information or characteristics, marital status, status as a Vietnam era veteran, special disabled veteran, or other protected veteran in accordance with applicable federal, state and local laws, and any other characteristic protected by law.

Locations

Boston, MA

Worker Type

Employee

Worker Sub-Type

Regular

Time Type

Job Exempt

Yes It is unlawful in Massachusetts to require or administer a lie detector test as a condition of employment or continued employment. An employer who violates this law shall be subject to criminal penalties and civil liability.
Not Specified
View & Apply
Director, Head of High-Throughput in vitro ADME
✦ New
🏢 Takeda Pharmaceutical Company Ltd
Salary not disclosed
Boston, Massachusetts 14 hours ago

By clicking the "Apply" button, I understand that my employment application process with Takeda will commence and that the information I provide in my application will be processed in line with Takeda's Privacy Notice and Terms of Use. I further attest that all information I submit in my employment application is true to the best of my knowledge.

Job Description

At Takeda, we are a forward-looking, world-class R&D organization that unlocks innovation and delivers transformative therapies to patients. By focusing R&D efforts on three therapeutic areas and other targeted investments, we push the boundaries of what is possible to bring life-changing therapies to patients worldwide.

Objective / Purpose:

The Director, High-Throughput In Vitro ADME is a senior scientific and operational leader responsible for building and directing Takeda's high-throughput in vitro ADME capabilities in support of small- and large-molecule discovery programs.

Reporting to the Head of Drug Discovery Lab Automation and Transformation, this Director will define strategy, oversee operations, and drive technology innovation at the interface of ADME science, laboratory automation, and robotics. The organization will operate as a service-oriented group, delivering robust, high-quality ADME data to enable rapid, high-confidence decision-making in Design–Make–Test–Analyze (DMTA) cycles across the portfolio.

Accountabilities:

  • Strategic Leadership & Vision
    • Define and execute the multi-year strategic roadmap for high-throughput in vitro ADME at Takeda, aligned with the broader vision of the Drug Discovery Lab Automation and Transformation organization.
    • Shape an enterprise-level, service-oriented operating model for ADME, ensuring capacity, capability, and flexibility to meet evolving project and portfolio needs.
    • Champion innovation in high throughput assay design, detection technologies, automation, and data workflows to enhance throughput, quality, and cost-effectiveness.
  • Team Leadership & People Development
    • Lead, mentor, and grow a team of scientists and research associates responsible for the routine delivery of a comprehensive suite of in vitro ADME assays.
    • Build a culture of scientific rigor, operational excellence, safety, and customer focus, supported by clear KPIs (e.g., cycle time, success rate, capacity utilization, cost-per-data point).
    • Drive talent development and performance management appropriate for a Director-level organization.
  • High-Throughput ADME Operations
    • Oversee design, execution, and continuous improvement of a broad high throughout in vitro ADME panel, including but not limited to:
    • Metabolic stability and clearance (microsomes, hepatocytes, S9)
      • CYP inhibition and induction
      • Permeability (e.g., Caco-2, MDCK, PAMPA)
      • Plasma protein and tissue binding
      • Transporter and other mechanistic assays
    • Ensure robust support for both small-molecule and large-molecule modalities, adapting methods for new modalities and platforms as the portfolio evolves.
    • Own and maintain fit-for-purpose validation, QC, and SOP frameworks, including root-cause analysis and corrective actions for assay or system deviations.
  • Laboratory Automation, Robotics & Miniaturization
    • Provide scientific and strategic leadership for laboratory automation and robotics within the in vitro ADME space, in close alignment with the Head of Drug Discovery Lab Automation and Transformation.
    • Lead assay miniaturization up to 1536-well formats, from feasibility and optimization through technology transfer into robust, routine operation.
    • Oversee integration of liquid handlers, plate handlers, robotic arms, incubators, readers, and scheduling software into end-to-end automated workflows.
    • Partner with internal automation/engineering and informatics teams to ensure seamless connectivity between instruments, LIMS/ELN, data pipelines, and analytical platforms.
  • Cross-Functional Collaboration
    • Serve as the primary ADME service leader interfacing with DMPK, medicinal chemistry, biology, pharmacology, translational sciences, and data science.
    • Translate portfolio and project needs into clear ADME assay strategies, capacity plans, and timelines; communicate priorities, risks, and trade-offs with transparency at project and governance levels.
    • Collaborate with external CROs, technology vendors, and academic partners when appropriate, ensuring consistent quality standards and strategic alignment with internal capabilities.
  • Quality, Compliance & Continuous Improvement
    • Ensure scientific quality, data integrity, and safety in all ADME operations, consistent with Takeda policies and relevant regulatory expectations.
    • Define and monitor KPIs for throughput, on-time delivery, reproducibility, and cost; apply data-driven methodologies (e.g., Lean, Six Sigma, DoE) to drive continuous improvement.
    • Oversee investigations and CAPA implementation related to assay performance, automation reliability, or data issues.
  • Education and Experience:
    • Expected: Ph.D. in Pharmaceutical Sciences, Drug Metabolism, Biochemistry, Pharmacology, or related field with 10+ years of relevant industry experience; or M.S. with 16+ years; or B.S. with 18+ years in pharmaceutical/biotech R&D.
    • Extensive expertise in in vitro ADME, including method development, validation, and deployment across core assay types.
    • Direct experience in an organization providing ADME services (e.g., CRO or internal ADME service group), with a strong service- and customer-oriented mindset.
    • Proven leadership experience at the Director level, managing scientific teams and complex operations in a high-throughput environment.
    • Demonstrated strategic and hands-on experience with laboratory automation and robotics, including selection, implementation, and lifecycle managemet.
    • Successful track record in miniaturizing ADME assays formats, including optimization for data quality, robustness, and throughput.
    • Experience supporting both small- and large-molecule discovery programs.
    • Familiarity with LIMS/ELN, instrument integration, and data analysis/visualization tools in a high-throughput setting.

Proven track record of:

  • Building or transforming high throughput ADME capabilities (e.g. establishing new platforms, scaling capacity, modernizing legacy workflows.
  • Understanding how ADME outputs integrate with DMPK, PK/PD and translational strategies and inform decision making
  • Experience with data science and process optimization approaches to support advanced analytics, and continuous improvement

ADDITIONAL INFORMATION

  • The position will be based in Cambridge, MA. This position is currently classified as "hybrid" by Takeda's Hybrid and Remote Work policy

Takeda Compensation and Benefits Summary

We understand compensation is an important factor as you consider the next step in your career. We are committed to equitable pay for all employees, and we strive to be more transparent with our pay practices.

For Location:

Boston, MA

U.S. Base Salary Range:

$174,500.00 - $274,230.00
The estimated salary range reflects an anticipated range for this position. The actual base salary offered may depend on a variety of factors, including the qualifications of the individual applicant for the position, years of relevant experience, specific and unique skills, level of education attained, certifications or other professional licenses held, and the location in which the applicant lives and/or from which they will be performing the job. The actual base salary offered will be in accordance with state or local minimum wage requirements for the job location.

U.S. based employees may be eligible for short-term and/ or long-term incentives. U.S. based employees may be eligible to participate in medical, dental, vision insurance, a 401(k) plan and company match, short-term and long-term disability coverage, basic life insurance, a tuition reimbursement program, paid volunteer time off, company holidays, and well-being benefits, among others. U.S. based employees are also eligible to receive, per calendar year, up to 80 hours of sick time, and new hires are eligible to accrue up to 120 hours of paid vacation.

EEO Statement

Takeda is proud in its commitment to creating a diverse workforce and providing equal employment opportunities to all employees and applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, gender expression, parental status, national origin, age, disability, citizenship status, genetic information or characteristics, marital status, status as a Vietnam era veteran, special disabled veteran, or other protected veteran in accordance with applicable federal, state and local laws, and any other characteristic protected by law.

Locations

Boston, MA

Worker Type

Employee

Worker Sub-Type

Regular

Time Type

Full time

Job Exempt

Yes It is unlawful in Massachusetts to require or administer a lie detector test as a condition of employment or continued employment. An employer who violates this law shall be subject to criminal penalties and civil liability.
Not Specified
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Research Senior Scientist, AI/ML (Biologics)
✦ New
🏢 Takeda Pharmaceutical Company Ltd
Salary not disclosed
Boston, Massachusetts 14 hours ago

By clicking the "Apply" button, I understand that my employment application process with Takeda will commence and that the information I provide in my application will be processed in line with Takeda's Privacy Notice and Terms of Use. I further attest that all information I submit in my employment application is true to the best of my knowledge.

Job Description

At Takeda, we are a forward-looking, world-class R&D organization that unlocks innovation and delivers transformative therapies to patients. By focusing R&D efforts on three therapeutic areas and other targeted investments, we push the boundaries of what is possible to bring life-changing therapies to patients worldwide.

The AI/ML organization at Takeda is building a team to transform how medicines are discovered. Our goal is to apply AI and machine learning across the entire drug discovery process, not just isolated steps, but as an integrated approach from target identification through development. This requires discernment: knowing which models and methods fit each problem, and the creativity to adapt when they don't. We work with foundational models, generative approaches, and autonomous systems, but the tools only matter when paired with people who understand the science deeply enough to use them well. Our team brings together computational scientists, biologists, engineers, and drug hunters. If you want to contribute your expertise to hard problems alongside colleagues with different perspectives, and help shape how AI delivers real impact in drug discovery, we'd like to hear from you.

Position Overview

We are seeking an innovative and dynamic AI/ML Research Senior Scientist with a passion for leveraging AI/ML in antibody discovery and design to join our Large Molecule AI/ML team. This role will be part of a multidisciplinary team focused on integrating advanced computational methods with cutting-edge experimental strategies to drive breakthrough discoveries in large molecule therapeutics and deepen our understanding of disease biology. The ideal candidate will have a strong background in computational biology, machine learning, and structural modeling and specifically with the application of AI/ML in biologics discovery.

Key Responsibilities

  • Develop and implement state-of-the-art AI/ML methodologies for de novo antibody design and discovery, including fine-tuning protein language models and generative protein design.
  • Develop, implement, and deploy advanced machine learning algorithms for the multi-objective optimization of antibodies, antigens, ADCs, and other biologics.
  • Build tools to incorporate data from integrated Design-Predict-Make-Confirm cycles with automated experimental platforms generating quality data at scale needed for project-specific and foundational models.
  • Innovate, develop, and apply predictive models for protein design and developability engineering, utilizing large-scale NGS, in vitro, in vivo and other proprietary in-house and external data sources.
  • Manage and process large-scale biological datasets for model training and evaluation
  • Stay abreast of advancements in NLP, ML, and generative AI to build novel tools that enhance therapeutic discovery and development.
  • Collaborate with internal experts to optimize the computational discovery infrastructure, offering both individual and team-based innovative solutions.
  • Communicate complex scientific ideas effectively to both technical and non-technical audiences, fostering collaboration across multidisciplinary teams.

Qualifications

  • PhD degree in a scientific discipline (or equivalent) with 2+ years relevant experience, or MS with 8+ years relevant experience, or BS with 10+ years relevant experience
  • Proven track record in developing machine learning models for chemical and biological data, including AI/ML-enabled molecular generation and affinity prediction.
  • Demonstrated experience in modeling antibody/ antigen sequence, structure and interaction.
  • Proficiency in programming languages such as Python and experience with cloud computing capabilities.
  • Strong analytical and problem-solving skills, with demonstrated creativity and the ability to contribute individually and collaboratively.
  • Versatile communicator who can elucidate complex ideas to non-specialists and commitment to continuous improvement and innovation.
  • Demonstrated learning agility, and scientific curiosity while maintaining focus on driving greater impact in the face of uncertainty and change.
  • Strong problem-solving aptitude and strategic thinking with an entrepreneurial mindset.

Preferred Qualifications & Skills:

  • Experience developing or applying modern ML architectures for antibody design models (LLMs, diffusion models, flow-matching, Bayesian Optimization, GNNs, etc.)
  • Experience designing de novo binders for specified targets and epitopes
  • Experience analyzing NGS-derived antibody repertoires for sequence- and structure-based design
  • Experience with molecular simulation and conformational analysis techniques

ADDITIONAL INFORMATION

  • The position will be based in Cambridge, MA

Takeda Compensation and Benefits Summary

We understand compensation is an important factor as you consider the next step in your career. We are committed to equitable pay for all employees, and we strive to be more transparent with our pay practices.

For Location:

Boston, MA

U.S. Base Salary Range:

$137,000.00 - $215,270.00
The estimated salary range reflects an anticipated range for this position. The actual base salary offered may depend on a variety of factors, including the qualifications of the individual applicant for the position, years of relevant experience, specific and unique skills, level of education attained, certifications or other professional licenses held, and the location in which the applicant lives and/or from which they will be performing the job. The actual base salary offered will be in accordance with state or local minimum wage requirements for the job location.

U.S. based employees may be eligible for short-term and/ or long-term incentives. U.S. based employees may be eligible to participate in medical, dental, vision insurance, a 401(k) plan and company match, short-term and long-term disability coverage, basic life insurance, a tuition reimbursement program, paid volunteer time off, company holidays, and well-being benefits, among others. U.S. based employees are also eligible to receive, per calendar year, up to 80 hours of sick time, and new hires are eligible to accrue up to 120 hours of paid vacation.

EEO Statement

Takeda is proud in its commitment to creating a diverse workforce and providing equal employment opportunities to all employees and applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, gender expression, parental status, national origin, age, disability, citizenship status, genetic information or characteristics, marital status, status as a Vietnam era veteran, special disabled veteran, or other protected veteran in accordance with applicable federal, state and local laws, and any other characteristic protected by law.

Locations

Boston, MA

Worker Type

Employee

Worker Sub-Type

Regular

Time Type

Full time

Job Exempt

Yes It is unlawful in Massachusetts to require or administer a lie detector test as a condition of employment or continued employment. An employer who violates this law shall be subject to criminal penalties and civil liability.
Not Specified
View & Apply
Senior Director, Medicinal Chemistry
✦ New
🏢 Takeda Pharmaceutical Company Ltd
Salary not disclosed
Boston, Massachusetts 14 hours ago

By clicking the "Apply" button, I understand that my employment application process with Takeda will commence and that the information I provide in my application will be processed in line with Takeda's Privacy Notice and Terms of Use. I further attest that all information I submit in my employment application is true to the best of my knowledge.

Job Description

We are seeking a seasoned and visionary Senior Director of Medicinal Chemistry to join our leadership team. This individual will play a pivotal role in shaping the future direction of our company by providing strategic guidance and oversight to our medicinal chemistry efforts. The ideal candidate will be instrumental in driving our drug discovery initiatives forward, ensuring their successful progression and alignment with our company's overall goals and objectives. By leveraging their expertise, they will significantly influence our strategic decisions and contribute to the advancement of our scientific and commercial endeavors. Additionally, this person will oversee external programs at CROs, managing the design, execution, and progression of medicinal chemistry projects conducted exclusively at these organizations

Accountabilities:

  • Create business development opportunities that meet the strategic scientific, therapeutic, and commercial needs of the organization or specific Therapeutic Area (TA).
  • Leadership and Strategy: Provide strategic leadership and oversight to the medicinal chemistry department, aligning with the company's overall goals and objectives.
  • Project Management: Oversee the design, execution, and management of medicinal chemistry projects conducted exclusively at CROs, ensuring timely progress and high-quality outcomes.
  • Team Development: Mentor and develop a team of internal chemists, fostering a collaborative and innovative work environment.
  • Collaboration: Work closely with cross-functional teams, including biology, pharmacology, and clinical development, to advance drug candidates from discovery through development.
  • Innovation: Drive innovation in medicinal chemistry through the integration of new technologies, methodologies, and best practices.
  • Regulatory Compliance: Ensure all activities comply with relevant regulatory requirements and industry standards.
  • External Partnerships: Build and maintain relationships with external partners, including academic institutions, industry collaborators, and contract research organizations.

Education & Competencies (Technical and Behavioral):

  • Expected education and experience: PhD degree in Chemistry, Medicinal Chemistry or related discipline with 15+ years experience in small molecule projects.
  • Proven track record of leading successful drug discovery programs, preferably in large pharma.
  • Leadership Skills: Strong leadership and managerial skills with experience leading and developing high-performing teams.
  • Technical Expertise: Deep understanding of medicinal chemistry principles, drug design, and optimization processes.
  • Communication: Excellent verbal and written communication skills, with the ability to effectively communicate complex scientific concepts to a broad audience.
  • Problem-Solving: Strong analytical and problem-solving skills, with a proactive and innovative approach to challenges.
  • Collaboration: Proven ability to work collaboratively in a cross-functional team environment.
  • Adaptability: Ability to adapt to changing priorities and work effectively in a fast-paced and dynamic environment.

Preferred Qualifications:

  • Experience: Experience in a leadership role within a large pharmaceutical or biotechnology company is highly desirable.
  • A proven track record of leading projects that are completely outsourced
  • Publications: A strong publication record in medicinal chemistry or related fields.
  • Patents: Experience with patent filings and intellectual property management.
  • Networking: Established network within the scientific and pharmaceutical community.
  • As part of our global R&D strategy, and unique to the Research organization's strong lab presence in Shonan, Japan, this role may include the opportunity for a temporary or long-term international assignment in Japan, subject to business needs and final candidate selection. Candidates interested in global exposure are encouraged to apply.

Takeda Compensation and Benefits Summary

We understand compensation is an important factor as you consider the next step in your career. We are committed to equitable pay for all employees, and we strive to be more transparent with our pay practices.

For Location:

Boston, MA

U.S. Base Salary Range:

$208,200.00 - $327,140.00
The estimated salary range reflects an anticipated range for this position. The actual base salary offered may depend on a variety of factors, including the qualifications of the individual applicant for the position, years of relevant experience, specific and unique skills, level of education attained, certifications or other professional licenses held, and the location in which the applicant lives and/or from which they will be performing the job. The actual base salary offered will be in accordance with state or local minimum wage requirements for the job location.

U.S. based employees may be eligible for short-term and/ or long-term incentives. U.S. based employees may be eligible to participate in medical, dental, vision insurance, a 401(k) plan and company match, short-term and long-term disability coverage, basic life insurance, a tuition reimbursement program, paid volunteer time off, company holidays, and well-being benefits, among others. U.S. based employees are also eligible to receive, per calendar year, up to 80 hours of sick time, and new hires are eligible to accrue up to 120 hours of paid vacation.

EEO Statement

Takeda is proud in its commitment to creating a diverse workforce and providing equal employment opportunities to all employees and applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, gender expression, parental status, national origin, age, disability, citizenship status, genetic information or characteristics, marital status, status as a Vietnam era veteran, special disabled veteran, or other protected veteran in accordance with applicable federal, state and local laws, and any other characteristic protected by law.

Locations

Boston, MA

Worker Type

Employee

Worker Sub-Type

Regular

Time Type

Full time

Job Exempt

Yes It is unlawful in Massachusetts to require or administer a lie detector test as a condition of employment or continued employment. An employer who violates this law shall be subject to criminal penalties and civil liability.
Not Specified
View & Apply
Executive Director, Head, Global Regulatory Information, Data & Systems
✦ New
🏢 Takeda Pharmaceutical Company Ltd
Salary not disclosed
Boston, Massachusetts 14 hours ago

By clicking the "Apply" button, I understand that my employment application process with Takeda will commence and that the information I provide in my application will be processed in line with Takeda's Privacy Notice and Terms of Use. I further attest that all information I submit in my employment application is true to the best of my knowledge.

Job Description

OBJECTIVES/PURPOSE:

Reporting to the Head, Global Regulatory Operations (GRO), the Head of Global Regulatory Information, Data and Systems (GRIDS) is responsible for developing and implementing a comprehensive GRIDS strategy. This pivotal role ensures Takeda's regulatory data integrity while driving the adoption and efficiency of Regulatory systems globally.

This role involves guiding and mentoring a team of experts, driving regulatory data quality confidence, ensuring global system reach and adoption, and enhancing efficiency through data connectivity across Global Regulatory Affairs (GRA), Research & Development (R&D), and the enterprise. Additionally, the role leads accurate and timely reporting for both common and ad hoc regulatory affairs questions.

ACCOUNTABILITIES:

Global GRIDS Strategy Development and Realization:

  • In partnership and collaboration with GRA and GRO leadership, Takeda IT functions, R&D cross-functional, and enterprise stakeholders, develop and align global GRIDS strategy and roadmap.
  • Execute and track GRIDS strategy through agreed to set of milestones, key deliverables, activities, and monitor progress through metrics. Proactively identify and manage risks and issues. Ensure ongoing stakeholder engagement and awareness throughout.
  • Align and structure internal GRIDS team to enable strategy realization and deliverables. Define team roles and responsibilities and ensure alignment across GRO and other functions to ensure clarity and synergy. Develop and implement team norms and ways of working, driving delivery focus and prioritization.
  • Actively mentor and guide direct reports in the execution of deliverables.
  • Ensure external vendor support for GRIDS activities is clearly defined and, in partnership with Business Operations team, is delivering to specified service level agreements. Actively provide vendor oversight and engage with vendor(s) to ensure process and ways-of-working clarity and adoption.

Data Governance and Sustainability:

  • Establish robust regulatory data governance and stewardship practices and ensure data quality assurance for authoritative regulatory data sources. Proactively drive data remediation efforts as needed to ensure high data quality.
  • Lead initiatives for regulatory information standards adoption and ensure organizational readiness to meet regulatory requirements, including eCTD4, SPOR/IDMP, and CTIS/EU CTR.
  • Oversee master data management for regulatory data and partner/ drive connectivity with RD and enterprise systems.

GRIDS Data Analytics:

  • Drive GRIDS business intelligence and data visualization capabilities to support data-driven decision making for Therapeutic Areas Units (TAUs), regulatory leadership, and other stakeholders for pipeline realization and post-approval lifecycle management.
  • Provide standard regulatory reports and dashboards and produce ad-hoc and custom regulatory reports as requested.

GRIDS System Business Ownership:

  • Partner with Takeda IT functions to drive the evolution, interoperability, data sharing, and integration of Takeda's global GRIDS systems.
  • Ensure business requirements are identified and adequately translated into system and supporting business process functionality.
  • Support system release management, data migration and validation activities.
  • Collaborate with GRA functions, regions, and local operating companies (LOCs) to drive system adoption and utilization.

CORE COMPETENCIES:

  • Strategy Development: Ability to create and implement long-term GRIDS strategies with a forward-thinking approach.
  • Influential Communicator: Exceptional communication skills to articulate complex regulatory data concepts effectively.
  • Collaborative Leader: Strong leadership qualities to guide cross-functional teams and drive organizational change.
  • Innovative Thinker: Proactive in embracing innovation and leveraging technology to enhance RIM processes.
  • Results-Oriented: Focused on achieving measurable outcomes and driving continuous improvement.
  • Analytical Skills: Strong analytical skills to interpret regulatory data and deliver insightful reports and visualizations.

QUALIFICATIONS:

  • Minimum Bachelor's Degree, MS preferred;
  • 15+ years of experience in the life sciences, particularly in Regulatory Affairs and Regulatory Information, Data and Systems.
  • Experience in leading global Regulatory Information, Data and Systems capabilities and teams.
  • Credibility and experience engaging at senior levels for the development and alignment of GRIDS strategy.
  • Ability to hold strategic conversations with Regulatory, R&D and enterprise stakeholders regarding global Information Management processes and systems and the regulatory applications and their use within Regulatory execution.
  • Demonstrated experience in designing and implementing RIM digital transformation with proven ability to innovate across business processes and technology solutions.
  • Experience with regulatory processes and technology for submission document authoring, submission publishing/validation/viewing, registration and commitment tracking, and regulatory document archiving.
  • Experience with regulatory data standards, such as xEVMPD and IDMP.
  • Deep understanding of the entire R&D value chain, particularly data taxonomies and domain integration.
  • Understanding of global drug development & regulatory processes.
  • Experience with Veeva RIM platform for health authority registration management.
  • Experience directly working with Registration Management, Submissions, Submissions Archive, and Publishing technologies, a plus.
  • Proven track record of thought leadership through industry presentations, publications, or other mechanisms, a plus.

This position is currently classified as "hybrid" by Takeda's Hybrid and Remote Work policy

Takeda Compensation and Benefits Summary

We understand compensation is an important factor as you consider the next step in your career. We are committed to equitable pay for all employees, and we strive to be more transparent with our pay practices.

For Location:

Boston, MA

U.S. Base Salary Range:

$208,200.00 - $327,140.00
The estimated salary range reflects an anticipated range for this position. The actual base salary offered may depend on a variety of factors, including the qualifications of the individual applicant for the position, years of relevant experience, specific and unique skills, level of education attained, certifications or other professional licenses held, and the location in which the applicant lives and/or from which they will be performing the job. The actual base salary offered will be in accordance with state or local minimum wage requirements for the job location.

U.S. based employees may be eligible for short-term and/ or long-term incentives. U.S. based employees may be eligible to participate in medical, dental, vision insurance, a 401(k) plan and company match, short-term and long-term disability coverage, basic life insurance, a tuition reimbursement program, paid volunteer time off, company holidays, and well-being benefits, among others. U.S. based employees are also eligible to receive, per calendar year, up to 80 hours of sick time, and new hires are eligible to accrue up to 120 hours of paid vacation.

EEO Statement

Takeda is proud in its commitment to creating a diverse workforce and providing equal employment opportunities to all employees and applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, gender expression, parental status, national origin, age, disability, citizenship status, genetic information or characteristics, marital status, status as a Vietnam era veteran, special disabled veteran, or other protected veteran in accordance with applicable federal, state and local laws, and any other characteristic protected by law.

Locations

Boston, MA

Worker Type

Employee

Worker Sub-Type

Regular

Time Type

Full time

Job Exempt

Yes It is unlawful in Massachusetts to require or administer a lie detector test as a condition of employment or continued employment. An employer who violates this law shall be subject to criminal penalties and civil liability.
Not Specified
View & Apply
Senior Field Vehicle Damage Assessor (BOSTON)
✦ New
🏢 Usaa
Salary not disclosed
Boston, Massachusetts 14 hours ago

Why USAA?

At USAA, our mission is to empower our members to achieve financial security through highly competitive products, exceptional service and trusted advice. We seek to be the #1 choice for the military community and their families.

Embrace a fulfilling career at USAA, where our core values – honesty, integrity, loyalty and service – define how we treat each other and our members. Be part of what truly makes us special and impactful.

The Opportunity

We are looking to hire a Sr. Field Auto Appraiser supporting the Boston Metro South, MA area.

As a dedicated Sr. Auto Appraiser, you will within defined guidelines and framework responsible for the investigation, negotiation, evaluation and appraisal of vehicle damage claims for both repairable and total loss vehicles to ensure estimate accuracy in compliance with state laws and regulations. Accountable for delivering exceptional member service through setting appropriate expectations, proactive communications, advice, and empathy.

What you'll do:

  • With the use of digital tools, evaluates and appraises highly complex auto physical damage claims in accordance with the terms and conditions of the contract, corporate guidelines and state laws and regulations.
  • Investigate claim damages including communicating with the insured, internal claims adjusters, and third parties/vendors. May require face-to-face interactions with members and third parties.
  • Review facts of loss and vehicle damage to determine if subrogation opportunities exist and ensures all supporting physical damage documentation is in the claim.
  • Demonstrate advanced knowledge of P&C insurance industry products, services, contracts, and internal processes/systems/procedures to ensure compliance with laws, regulations, and policy provisions.
  • Review claims/suppliers for fraud indicators and refers to Special Investigations Unit for handling, if applicable.
  • Maintain accurate and current claim file documentation throughout the claims process for complex claims.
  • Maintain high standards of productivity through effective desk management, timely follow ups, and accurate mapping of repair plan and timeline for repair in support of fast and accurate claims adjudication.
  • Responsible for reviewing additional damages received from repair facilities to either complete a supplement or triage to field provider method of inspection.
  • May serve as a subject matter expert representative for disputed claims or trials. Serves as a resource to team members on escalated issues of a routine nature.
  • Partner with vendors and internal business partners to facilitate highest complexity claims resolution. May also involve external regulatory coordination to ensure appropriate documentation and compliance.
  • Proactively provide policyholders with information regarding their coverage, repair estimate or total loss valuation, and claims/repair process while setting appropriate expectations.
  • Support workload surges and catastrophe (CAT) response operations as needed, including mandatory on-call dates and potential evening, weekend, and/or holiday work outside normal work hours.
  • May be assigned CAT deployment travel with minimal notice during designated CATs.
  • Work various types of claims, including ones of higher complexity, and may be assigned additional work outside normal duties as needed.
  • Ensure risks associated with business activities are effectively identified, measured, monitored, and controlled in accordance with risk and compliance policies and procedures.

What you have:

  • High School Diploma or General Equivalency Diploma.
  • 2 years of auto appraising experience.
  • Proficient knowledge of P&C insurance policy contracts and coverages, auto parts distribution process and claim appraisal process and procedures.
  • Advanced working knowledge of estimating losses using CCC or similar estimating platforms.
  • Demonstrated written and verbal skills to communicate with members, claimants, repair facilities, and other internal and external stakeholders.
  • Acquisition and maintenance of insurance adjuster license within 90 days and 3 attempts.

Physical Demand Requirements:

  • May require the ability to operate a company vehicle within assigned territory.
  • May require the ability to reach, handle, squat, bend, climb, and kneel as needed to complete inspections of damaged vehicles.
  • May require the ability to work outdoors in inclement weather conditions; May be exposed to working in body shop and/or salvage yard environments up to 25% of the time.
  • May be required to meet all USAA safe driving requirements including verification of driving record through MVR & possession of valid driver's license.

Compensation range: The salary range for this position is: $63,590 - $121,530.

USAA does not provide visa sponsorship for this role. Please do not apply for this role if at any time (now or in the future) you will need immigration support (i.e., H-1B, TN, STEM OPT Training Plans, etc.).

Compensation: USAA has an effective process for assessing market data and establishing ranges to ensure we remain competitive. You are paid within the salary range based on your experience and market data of the position. The actual salary for this role may vary by location.

Employees may be eligible for pay incentives based on overall corporate and individual performance and at the discretion of the USAA Board of Directors.

The above description reflects the details considered necessary to describe the principal functions of the job and should not be construed as a detailed description of all the work requirements that may be performed in the job.

Benefits: At USAA our employees enjoy best-in-class benefits to support their physical, financial, and emotional wellness. These benefits include comprehensive medical, dental and vision plans, 401(k), pension, life insurance, parental benefits, adoption assistance, paid time off program with paid holidays plus 16 paid volunteer hours, and various wellness programs. Additionally, our career path planning and continuing education assists employees with their professional goals.

For more details on our outstanding benefits, visit our benefits page on

Applications for this position are accepted on an ongoing basis, this posting will remain open until the position is filled. Thus, interested candidates are encouraged to apply the same day they view this posting.

USAA is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, or status as a protected veteran.

Not Specified
View & Apply
Senior Manager, Clinical Partner Outsourcing
✦ New
🏢 Takeda Pharmaceutical Company Ltd
Salary not disclosed
Boston, Massachusetts 14 hours ago

By clicking the "Apply" button, I understand that my employment application process with Takeda will commence and that the information I provide in my application will be processed in line with Takeda's Privacy Notice and Terms of Use. I further attest that all information I submit in my employment application is true to the best of my knowledge.

Job Description

At Takeda, we are a forward-looking, world-class R&D organization that unlocks innovation and delivers transformative therapies to patients. By focusing R&D efforts on three therapeutic areas and other targeted investments, we push the boundaries of what is possible to bring life-changing therapies to patients worldwide.

Objective / Purpose:

The Senior Manager, Clinical Partner Outsourcing (CPO) ensures seamless execution of clinical studies by developing robust supplier contracts through commercial negotiations and resolving commercial and operational challenges. This role is responsible for ensuring a high level of fiscal discipline as well as enhancing cross-functional collaboration, and ensuring studies start on time, aligned to business requirements and Takeda standards and with the right commercial structures in place.

Accountabilities:

  • Responsible for the development and finalization of study level contracts and change orders in partnership with key functions and aligned with Master Service Agreements, to ensure predictable delivery, quality and alignment to Takeda's requirements, values and policies.
  • Lead ballparking, contracting and commercial management of complex clinical studies, understanding study requirements and translating into robust supplier contracts across a broad category of suppliers supporting R&D activities for assigned therapeutic areas and studies
  • Apply appropriate commercial constructs, aligned to business requirements, to enable study start, even with evolving assumptions
  • Utilize cost models and workbooks to validate contract pricing and budget assumptions for complex agreements and develop enhancements to improve validation capabilities
  • Drive negotiations with CRO's and suppliers to secure optimal terms for Takeda
  • Manage contract amendments throughout the study lifecycle
  • Support study teams in completing final reconciliation at study closeout
  • Develop close collaborative working relationships with clinical operations and other key stakeholders to improve understanding and engagement
  • Generate preliminary cost estimates to support Study Execution Teams (SET) in budget planning
  • Collaborate with study teams to address commercial/contractual challenges, proactively identify potential issues, develop contingency plans and escalate to Clinical Partner Outsourcing/SPO leadership as necessary
  • Escalate issues through the appropriate channels when local resolution is not achievable
  • Drive operational support & issue resolution by supporting teams in addressing operational and performance-related supplier issues
  • Ensure consistency between contractual agreement and operational implementation
  • Serve as a SME and lead continuous improvement initiatives to enhance performance and efficiency, identify best practices through industry benchmarking.
  • As a member of the CPO team, anticipate and identify external industry trends impacting Takeda's operating/cost model
  • Ensure compliance with all applicable internal policies and procedures, regulations, support inspection readiness of all regulated activities.
  • Lead or participate in special projects and initiatives to support the business

Education & Competencies (Technical and Behavioral):

  • Bachelors degree required; advanced technical degree (e.g MBA) or certifications (e.g PMP, CPA) preferred
  • 7+ years of experience in the pharmaceutical industry or clinical research environment
  • Experience supporting a complex organization and demonstrated ability to work across functions and regions
  • Proven experience in clinical procurement, contract management, or supplier relationship management
  • Strong knowledge of clinical trial processes and regulatory requirements
  • Experience in contract negotiations, financial analysis and budget management.
  • Familiarity with CRO and clinical outsourcing models, including financial and commercial constructs
  • Sound understanding of GCP, ICH guidelines, and clinical trial regulations
  • Strong strategic thinking and project management skills
  • Excellent communicator with strong written and verbal presentation skills

ADDITIONAL INFORMATION:

  • The position will be based in Cambridge, MA. This position is currently classified as "remote" by Takeda's Hybrid and Remote Work policy.

Takeda Compensation and Benefits Summary

We understand compensation is an important factor as you consider the next step in your career. We are committed to equitable pay for all employees, and we strive to be more transparent with our pay practices.

For Location:

Boston, MA

U.S. Base Salary Range:

$137,000.00 - $215,270.00
The estimated salary range reflects an anticipated range for this position. The actual base salary offered may depend on a variety of factors, including the qualifications of the individual applicant for the position, years of relevant experience, specific and unique skills, level of education attained, certifications or other professional licenses held, and the location in which the applicant lives and/or from which they will be performing the job. The actual base salary offered will be in accordance with state or local minimum wage requirements for the job location.

U.S. based employees may be eligible for short-term and/ or long-term incentives. U.S. based employees may be eligible to participate in medical, dental, vision insurance, a 401(k) plan and company match, short-term and long-term disability coverage, basic life insurance, a tuition reimbursement program, paid volunteer time off, company holidays, and well-being benefits, among others. U.S. based employees are also eligible to receive, per calendar year, up to 80 hours of sick time, and new hires are eligible to accrue up to 120 hours of paid vacation.

EEO Statement

Takeda is proud in its commitment to creating a diverse workforce and providing equal employment opportunities to all employees and applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, gender expression, parental status, national origin, age, disability, citizenship status, genetic information or characteristics, marital status, status as a Vietnam era veteran, special disabled veteran, or other protected veteran in accordance with applicable federal, state and local laws, and any other characteristic protected by law.

Locations

Boston, MA

Worker Type

Employee

Worker Sub-Type

Regular

Time Type

Full time

Job Exempt

Yes It is unlawful in Massachusetts to require or administer a lie detector test as a condition of employment or continued employment. An employer who violates this law shall be subject to criminal penalties and civil liability.
Not Specified
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Lead Mobile Automotive Adjuster (BOSTON)
✦ New
🏢 Usaa
Salary not disclosed
Boston, Massachusetts 14 hours ago

Why USAA?

At USAA, our mission is to empower our members to achieve financial security through highly competitive products, exceptional service and trusted advice. We seek to be the #1 choice for the military community and their families.

Embrace a fulfilling career at USAA, where our core values – honesty, integrity, loyalty and service – define how we treat each other and our members. Be part of what truly makes us special and impactful.

The Opportunity

We are looking to hire a Sr. Field Auto Appraiser supporting the Boston Metro South, MA area.

As a dedicated Sr. Auto Appraiser, you will within defined guidelines and framework responsible for the investigation, negotiation, evaluation and appraisal of vehicle damage claims for both repairable and total loss vehicles to ensure estimate accuracy in compliance with state laws and regulations. Accountable for delivering exceptional member service through setting appropriate expectations, proactive communications, advice, and empathy.

What you'll do:

  • With the use of digital tools, evaluates and appraises highly complex auto physical damage claims in accordance with the terms and conditions of the contract, corporate guidelines and state laws and regulations.
  • Investigate claim damages including communicating with the insured, internal claims adjusters, and third parties/vendors. May require face-to-face interactions with members and third parties.
  • Review facts of loss and vehicle damage to determine if subrogation opportunities exist and ensures all supporting physical damage documentation is in the claim.
  • Demonstrate advanced knowledge of P&C insurance industry products, services, contracts, and internal processes/systems/procedures to ensure compliance with laws, regulations, and policy provisions.
  • Review claims/suppliers for fraud indicators and refers to Special Investigations Unit for handling, if applicable.
  • Maintain accurate and current claim file documentation throughout the claims process for complex claims.
  • Maintain high standards of productivity through effective desk management, timely follow ups, and accurate mapping of repair plan and timeline for repair in support of fast and accurate claims adjudication.
  • Responsible for reviewing additional damages received from repair facilities to either complete a supplement or triage to field provider method of inspection.
  • May serve as a subject matter expert representative for disputed claims or trials. Serves as a resource to team members on escalated issues of a routine nature.
  • Partner with vendors and internal business partners to facilitate highest complexity claims resolution. May also involve external regulatory coordination to ensure appropriate documentation and compliance.
  • Proactively provide policyholders with information regarding their coverage, repair estimate or total loss valuation, and claims/repair process while setting appropriate expectations.
  • Support workload surges and catastrophe (CAT) response operations as needed, including mandatory on-call dates and potential evening, weekend, and/or holiday work outside normal work hours.
  • May be assigned CAT deployment travel with minimal notice during designated CATs.
  • Work various types of claims, including ones of higher complexity, and may be assigned additional work outside normal duties as needed.
  • Ensure risks associated with business activities are effectively identified, measured, monitored, and controlled in accordance with risk and compliance policies and procedures.

What you have:

  • High School Diploma or General Equivalency Diploma.
  • 2 years of auto appraising experience.
  • Proficient knowledge of P&C insurance policy contracts and coverages, auto parts distribution process and claim appraisal process and procedures.
  • Advanced working knowledge of estimating losses using CCC or similar estimating platforms.
  • Demonstrated written and verbal skills to communicate with members, claimants, repair facilities, and other internal and external stakeholders.
  • Acquisition and maintenance of insurance adjuster license within 90 days and 3 attempts.

Physical Demand Requirements:

  • May require the ability to operate a company vehicle within assigned territory.
  • May require the ability to reach, handle, squat, bend, climb, and kneel as needed to complete inspections of damaged vehicles.
  • May require the ability to work outdoors in inclement weather conditions; May be exposed to working in body shop and/or salvage yard environments up to 25% of the time.
  • May be required to meet all USAA safe driving requirements including verification of driving record through MVR & possession of valid driver's license.

Compensation range: The salary range for this position is: $63,590 - $121,530.

USAA does not provide visa sponsorship for this role. Please do not apply for this role if at any time (now or in the future) you will need immigration support (i.e., H-1B, TN, STEM OPT Training Plans, etc.).

Compensation: USAA has an effective process for assessing market data and establishing ranges to ensure we remain competitive. You are paid within the salary range based on your experience and market data of the position. The actual salary for this role may vary by location.

Employees may be eligible for pay incentives based on overall corporate and individual performance and at the discretion of the USAA Board of Directors.

The above description reflects the details considered necessary to describe the principal functions of the job and should not be construed as a detailed description of all the work requirements that may be performed in the job.

Benefits: At USAA our employees enjoy best-in-class benefits to support their physical, financial, and emotional wellness. These benefits include comprehensive medical, dental and vision plans, 401(k), pension, life insurance, parental benefits, adoption assistance, paid time off program with paid holidays plus 16 paid volunteer hours, and various wellness programs. Additionally, our career path planning and continuing education assists employees with their professional goals.

For more details on our outstanding benefits, visit our benefits page on

Applications for this position are accepted on an ongoing basis, this posting will remain open until the position is filled. Thus, interested candidates are encouraged to apply the same day they view this posting.

USAA is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, or status as a protected veteran.

Not Specified
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Senior Director, Clinical Data Standards
✦ New
🏢 Takeda Pharmaceutical Company Ltd
Salary not disclosed
Boston, Massachusetts 14 hours ago

By clicking the "Apply" button, I understand that my employment application process with Takeda will commence and that the information I provide in my application will be processed in line with Takeda's Privacy Notice and Terms of Use. I further attest that all information I submit in my employment application is true to the best of my knowledge.

Job Description

Are you looking for a patient-focused, innovation-driven company to inspire you and empower you to shine? Join us as a Senior Director, Clinical Data Standards based remotely reporting to the Vice President, Clinical Data Operations & Standards.

At Takeda, we are transforming the pharmaceutical industry through our R&D-driven market leadership and being a values-led company. To do this, we empower our people to work towards their potential through life-changing work. Certified as a Global Top Employer, we offer stimulating careers, and work toward excellence in everything we do. We foster an inclusive, collaborative workplace, in which our global teams are united by an unwavering commitment to provide Better Health and a Brighter Future to people around the world.

Here, you will be a necessary contributor to our inspiring, bold mission.

GOALS:

  • In collaboration with the Clinical Data Strategy & Operations Leaders, and TAU Leaders, and other functional area leadership to develop, establishes and drives strategy of Takeda's global data standards, processes and technologies across the clinical data continuum for quality of deliverables and global data interoperability.
  • Responsible for establishing and managing a Standards vendor to support Standards Management vision.
  • Responsible for end-to-end Standards Governance to ensure proper utilization, adherence to standards governance and processes, and the ongoing, thorough assessment of library enhancements and deviations.
  • Build relationships across the global Takeda organization and with vendor partners in support of the standards vision and implementation.
  • Participates with and influences at industry standards forums in support of Takeda's therapeutic areas.
  • Serves as a resource to support questions raised by regulatory agencies.

ACCOUNTABILITIES:

  • Has advanced knowledge of all standard library components and metadata across data collection, analysis and reporting continuum.
  • Works with Clinical Data Strategy & Operations Leaders, TAU Leaders, and other functional area leadership to develop, and adhere to, Standards Management vision and overall metadata management strategy.
  • Leads cross-functional Standards initiatives internal or external to Takeda and helps to ensure coherence of standards initiatives across organization.
  • Provides strategic guidance toward execution of comprehensive data continuum to staff and vendors acting as project managers or leads on cross-functional initiatives.
  • Supervises staff and vendors developing standards library to ensure alignment to standards strategy.
  • Develops training strategy and ensures consistent training program for standards.
  • Provides senior oversight to vendor/CROs for utilization of Takeda standards.
  • Conducts ongoing review and development of metrics to assess standards utilization and development trends.
  • Oversees Standards Governance, managing deviations from standards content and processes.
  • Drives ongoing development and improvement of industry standards and provides leadership to external professional activities and organizations, such as CDISC, SCDM, EDC users group, SAS users group, Third Party Data Acquisition groups, etc.
  • Actively communicates submission standards and guidance documents, regulatory agency expectations and industry trends to Takeda organization.
  • Complies with all applicable regulatory expectations.

EDUCATION AND EXPERIENCE:

  • BS/BA or MS in a life science or analytical area.
  • 12 years data management and/or database or statistical programming experience in pharmaceutical industry or health related field.
  • 8+ years of experience supporting clinical trials across all phases of development.
  • 5+ years of progressive management experience.
  • Proven track record for development and management of a standards library.
  • In-depth knowledge of data management systems and processes, analysis and reporting principles.
  • Good knowledge of statistical programming languages (e.g. SAS).
  • Technical expertise (e.g. Windows NT and UNIX operating systems) and familiarity with common software products and technologies used in conjunction with SAS.
  • Expertise in the requirements and technology required to support electronic data capture and electronic submissions.
  • Proven track record in identifying and implementing organization-wide initiatives, standards, and processes.
  • Proven track record in managing global, cross-functional standards and processes.
  • Knowledge of medical and statistical terminology. Comprehensive understanding of pharmaceutical standard initiatives such as CDISC (ADaM, SDTM, CDASH and ODM), HL7, etc.)
  • Able to influence without authority.
  • Excellent teamwork, organizational, interpersonal, conflict resolution and problem-solving skills.
  • Entrepreneurial and innovative; takes measured risks; thinks outside the box; challenges the status quo.
  • Pragmatic and willing to drive and support change.
  • Is comfortable with ambiguity .
  • Support a culture of continual improvement and innovation; promote knowledge sharing.

Takeda Compensation and Benefits Summary

We understand compensation is an important factor as you consider the next step in your career. We are committed to equitable pay for all employees, and we strive to be more transparent with our pay practices.

For Location:

Massachusetts - Virtual

U.S. Base Salary Range:

$208,200.00 - $327,140.00
The estimated salary range reflects an anticipated range for this position. The actual base salary offered may depend on a variety of factors, including the qualifications of the individual applicant for the position, years of relevant experience, specific and unique skills, level of education attained, certifications or other professional licenses held, and the location in which the applicant lives and/or from which they will be performing the job. The actual base salary offered will be in accordance with state or local minimum wage requirements for the job location.

U.S. based employees may be eligible for short-term and/ or long-term incentives. U.S. based employees may be eligible to participate in medical, dental, vision insurance, a 401(k) plan and company match, short-term and long-term disability coverage, basic life insurance, a tuition reimbursement program, paid volunteer time off, company holidays, and well-being benefits, among others. U.S. based employees are also eligible to receive, per calendar year, up to 80 hours of sick time, and new hires are eligible to accrue up to 120 hours of paid vacation.

EEO Statement

Takeda is proud in its commitment to creating a diverse workforce and providing equal employment opportunities to all employees and applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, gender expression, parental status, national origin, age, disability, citizenship status, genetic information or characteristics, marital status, status as a Vietnam era veteran, special disabled veteran, or other protected veteran in accordance with applicable federal, state and local laws, and any other characteristic protected by law.

Locations

Massachusetts - Virtual

Worker Type

Employee

Worker Sub-Type

Regular

Time Type

Full time

Job Exempt

Yes It is unlawful in Massachusetts to require or administer a lie detector test as a condition of employment or continued employment. An employer who violates this law shall be subject to criminal penalties and civil liability.

#LI-Remote

Not Specified
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Research Scientist AI/ML Foundational Models
✦ New
🏢 Takeda Pharmaceutical Company Ltd
Salary not disclosed
Boston, Massachusetts 14 hours ago

By clicking the "Apply" button, I understand that my employment application process with Takeda will commence and that the information I provide in my application will be processed in line with Takeda's Privacy Notice and Terms of Use. I further attest that all information I submit in my employment application is true to the best of my knowledge.

Job Description

At Takeda, we are a forward-looking, world-class R&D organization that unlocks innovation and delivers transformative therapies to patients. By focusing R&D efforts on three therapeutic areas and other targeted investments, we push the boundaries of what is possible to bring life-changing therapies to patients worldwide.

The AI/ML organization at Takeda is building a team to transform how medicines are discovered. Our goal is to apply AI and machine learning across the entire drug discovery process, not just isolated steps, but as an integrated approach from target identification through development. This requires discernment: knowing which models and methods fit each problem, and the creativity to adapt when they don't. We work with foundational models, generative approaches, and autonomous systems, but the tools only matter when paired with people who understand the science deeply enough to use them well. Our team brings together computational scientists, biologists, engineers, and drug hunters. If you want to contribute your expertise to hard problems alongside colleagues with different perspectives and help shape how AI delivers real impact in drug discovery, we'd like to hear from you.

Position Overview:

We are seeking Scientists to develop and deploy foundational AI models that will transform drug discovery across Takeda. As part of the AI/ML Foundation team, you will build large-scale models including large language models (LLMs), diffusion models, and multimodal architectures that integrate diverse data types—omics, biomedical imaging, protein 3D structures, and molecular representations. This role requires deep expertise in modern deep learning architectures combined with foundational knowledge of biology, chemistry, and disease biology to ensure models are scientifically grounded and impactful. You will train models from scratch, fine-tune pre-trained models for Takeda-specific applications, and deploy foundation model capabilities that accelerate discovery across all therapeutic platforms.

Accountabilities:

  • Develop and train foundational AI models (LLMs, diffusion models, flow-matching architectures) for drug discovery applications, with capability to pre-train on large-scale scientific corpora and molecular datasets.
  • Fine-tune and adapt pre-trained foundation models (protein language models, chemical LLMs, vision transformers) for Takeda-specific applications in target identification, disease modeling, and molecular design and discovery.
  • Build multimodal foundation models integrating diverse data types including omics (genomics, transcriptomics, proteomics), biomedical imaging, protein 3D structures, and molecular representations.
  • Apply and extend state-of-the-art approaches including graph neural networks, transformer-based protein language models, and multimodal learning frameworks.
  • Apply domain expertise in biology, chemistry, and/or disease biology to guide model architecture decisions, training data curation, and evaluation strategies ensuring scientific validity.
  • Implement state-of-the-art generative architectures (diffusion, score-based models, autoregressive transformers) for molecular generation, protein design, and multi-objective optimization.
  • Collaborate with computational scientists across domains to deploy foundation models that address diverse discovery needs across small molecules, biologics, and emerging modalities.
  • Stay current with advances in foundation models, generative AI, and multimodal learning; contribute to internal knowledge sharing and external publications.

Education & Requirements:

  • PhD in Computer Science, Machine Learning, Computational Biology, Bioinformatics, or related field or MS with 6+ years relevant experience, or BS with 8+ years relevant experience
  • Deep expertise in modern deep learning architectures including transformers, diffusion models, and/or generative models.
  • Strong experience training large-scale models with proficiency in PyTorch and distributed training frameworks.
  • Foundational knowledge of biology, chemistry, or disease biology sufficient to guide scientifically meaningful model development.
  • Experience with at least one of: protein language models (ESM, ProtTrans), molecular generative models, or biomedical vision models.
  • Experience with cloud computing (AWS, GCP) and GPU cluster training at scale.

Preferred:

  • Experience building or fine-tuning foundation models in pharmaceutical or life sciences settings.
  • Expertise in multimodal learning integrating text, images, and structured molecular data.
  • Experience with omics data analysis (genomics, transcriptomics, proteomics) and knowledge graph
  • Familiarity with protein structure prediction and 3D molecular representations.
  • Publications in top-tier ML venues (NeurIPS, ICML, ICLR) or computational biology journals.
  • Experience with model compression, efficient inference, or production deployment of large models.
  • Strong background in large-scale data integration and multimodal modeling for biological systems.
  • Proficiency in Python and ML libraries (PyTorch, TensorFlow, scikit-learn); familiarity with Unix tools.
  • Excellent collaboration and communication skills.

ADDITIONAL INFORMATION

  • The position will be based in Cambridge, MA

Takeda Compensation and Benefits Summary

We understand compensation is an important factor as you consider the next step in your career. We are committed to equitable pay for all employees, and we strive to be more transparent with our pay practices.

For Location:

Boston, MA

U.S. Base Salary Range:

$111,800.00 - $175,670.00
The estimated salary range reflects an anticipated range for this position. The actual base salary offered may depend on a variety of factors, including the qualifications of the individual applicant for the position, years of relevant experience, specific and unique skills, level of education attained, certifications or other professional licenses held, and the location in which the applicant lives and/or from which they will be performing the job. The actual base salary offered will be in accordance with state or local minimum wage requirements for the job location.

U.S. based employees may be eligible for short-term and/ or long-term incentives. U.S. based employees may be eligible to participate in medical, dental, vision insurance, a 401(k) plan and company match, short-term and long-term disability coverage, basic life insurance, a tuition reimbursement program, paid volunteer time off, company holidays, and well-being benefits, among others. U.S. based employees are also eligible to receive, per calendar year, up to 80 hours of sick time, and new hires are eligible to accrue up to 120 hours of paid vacation.

EEO Statement

Takeda is proud in its commitment to creating a diverse workforce and providing equal employment opportunities to all employees and applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, gender expression, parental status, national origin, age, disability, citizenship status, genetic information or characteristics, marital status, status as a Vietnam era veteran, special disabled veteran, or other protected veteran in accordance with applicable federal, state and local laws, and any other characteristic protected by law.

Locations

Boston, MA

Worker Type

Employee

Worker Sub-Type

Regular

Time Type

Full time

Job Exempt

Yes It is unlawful in Massachusetts to require or administer a lie detector test as a condition of employment or continued employment. An employer who violates this law shall be subject to criminal penalties and civil liability.
Not Specified
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QC Scientist – Flow Cytometry (Cell Therapy)
✦ New
Salary not disclosed
Lexington, MA 14 hours ago

The role:

The Quality Control Scientist is responsible for execution and oversight of analytical, microbiological, and environmental testing to ensure the safety and quality of cell therapy products and manufacturing operations. The role includes performing GMP testing to support development, donor screening, in-process control, product release, stability, raw material release, and environmental monitoring in accordance with Standard Operating Procedures (SOPs). The QC Scientist serves as a technical resource for analytical methods such as flow cytometry and other cell-based assays, supports assay and equipment qualification, and ensures data integrity and regulatory compliance. Additional responsibilities include authoring or revising procedures, leading continuous improvement initiatives, supporting investigations, contributing to assay development efforts, and train staff as needed.


In the role you will:

  • Perform analytical, microbiological, and environmental testing in support of development, donor-screening, in-process control, product release, stability, and raw-material release in accordance with SOPs and GMP requirements.
  • Serve as a technical lead for flow-cytometry–based analytical assays, including instrument setup, compensation, gating strategy, data analysis, and troubleshooting.
  • Perform and review cell count assays and evaluate data.
  • Support method qualification, validation, and transfer for flow cytometry, cell counting, and other analytical assays; ensure accurate, reproducible data generation.
  • Conduct environmental and personnel monitoring of controlled areas, including viable air, non-viable particulates, surface, and gowning monitoring.
  • Oversee environmental data entry, review, and trend analysis; evaluate results against alert and action levels and support investigations for excursions or adverse trends.
  • Execute and review microbiological assays such as sterility, endotoxin (LAL), bioburden, gram staining, growth-promotion, and conductivity/TOC testing.
  • Participate in aseptic process simulation (media-fill) runs; provide on-floor QC support during execution and perform subsequent media incubation, inspection, and documentation.
  • Sample, test, and document raw-material results and manage disposition.
  • Establish and manage relationships with qualified contract laboratories; oversee external testing activities, ensure timely data delivery, review results, and verify accuracy for inclusion in release documentation.
  • Compile, verify, and review analytical and microbiological data to support generation of Certificates of Analysis (CoA) for raw materials, intermediates, and drug-product release.
  • Oversight of stability testing for intermediates and product to support shelf-life claims and IND submission.
  • Author and revise SOPs, test methods, and data records; contribute to laboratory continuous-improvement initiatives.
  • Author and revise technical reports and support IND submissions.
  • Support and provide technical input to deviation, OOS, and CAPA investigations, ensuring scientific rationale and data integrity.
  • Participate in equipment calibration, qualification, and maintenance programs, and assist in implementation of new or revised analytical methods.
  • Train staff in flow cytometry, microbiological methods, and GMP documentation practices.
  • Maintain compliance with GMP, data-integrity, and safety requirements, ensuring laboratory readiness for internal and regulatory inspections.
  • Provide input to QC metrics and data-trending reports for management review.
  • Maintain a flexible schedule to accommodate manufacturing and testing demands, including periodic weekend, holiday, or extended-hour work and off-shift coverage as needed.


Qualifications: About you

  • Minimum 4-6 years relevant QC experience in a GMP and cleanroom environment, supporting biologics or cell therapy products.
  • Demonstrated proficiency in analytical and microbiological testing, including flow cytometry, cell counting, endotoxin, sterility, and environmental monitoring.
  • Proven experience supporting method qualification, validation, and transfer activities.
  • Strong understanding of data review, good documentation practices, and data integrity.
  • Experience conducting and authoring investigations, CAPA development, and laboratory deviation documentation.
  • Experience collaborating cross-functionally with Manufacturing, QA, and Analytical Development teams to support GMP operations.
  • Requires Bachelor’s degree in a scientific discipline or equivalent combination of education and experience.
  • Expertise in flow cytometry, including instrument setup, compensation, gating, and data analysis.
  • Experience leading method qualification, transfer, and troubleshooting for analytical and microbiological assays.
  • Advanced understanding of aseptic technique and contamination control in GMP cleanroom operations.
  • Experience performing or reviewing microbiological assays, including endotoxin (LAL), sterility, bioburden, gram staining and growth-promotion testing.
  • Familiarity with environmental and personnel monitoring, including data trending and evaluation against alert/action levels.
  • Experience performing or reviewing in-process and release testing for cell-based products.
  • Strong knowledge of raw material testing programs, including identity, endotoxin, and bioburden verification.
  • Experience coordinating and reviewing external testing with qualified contract laboratories.
  • Proficiency in data review, trending, and reporting using paper or electronic based systems.
  • Strong understanding and ability for authoring f GMP documentation, investigations, and change controls.
  • Ability to train and qualify analysts in technical procedures and GMP compliance.
  • Proactive, self-motivated team player who is comfortable working in a dynamic, fast-paced manufacturing setting, working independently with minimal supervision and adapting to changing schedules.

The targeted salary range for this position is $95,000 - $129,600 per year. MiNK is making a good faith effort to be transparent and accurate around our hiring ranges. The salary offered is commensurate with MiNK's compensation philosophy and considers factors including, but not limited to, education, training, experience, external market conditions, critical needs of the role, and internal equity.

Not Specified
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Account Executive Sales Representative
✦ New
Salary not disclosed
Watertown, MA 14 hours ago

Account Executive

WORLDWIDE EXPRESS


The largest non-retail authorized UPS® partner and No. 1 largest privately held LTL broker in the country!


The Account Executive position at Worldwide Express is a unique and rewarding outside business-to-business(B2B) sales opportunity for the salesperson looking for unlimited growth potential and uncapped residual commission coupled with a healthy base salary and monthly allowances. This unique compensation plan allows top performers to earn an annual six-figure income within 18 to 24 months.


PERFORMANCE RESPONSIBILITIES:

Consult, educate and simplify supply chain practices through an innovative, web-based platform. Streamline in and outbound processes, providing customized solutions.

  • Lead presentations with executives/owners of businesses with frequent shipping volume
  • Partner with the operations and account management teams for optimal customer satisfaction
  • Solution selling; effectively present solutions through cost-benefit analysis
  • Present a streamlined technology solution developing a detailed analysis of customized needs in challenging areas and lanes
  • Take the lead in coordinating/developing/managing all aspects of the proposal process
  • Close, activate and train decision-makers on our exclusive shipping platform


WHAT WE EXPECT FROM YOU:

A competitive and motivated mindset and a passion for new business development.

  • Bachelor's Degree preferred
  • Proven success in generating/qualifying leads through prospecting new business with a ‘hunter’ mentality
  • High energy, with a passion for your personal brand and the ability to carry yourself like an executive
  • Comfortable in a fast-paced, quota-driven, results-oriented environment
  • Effective communicator with strong business acumen and intuition
  • Self-starter with strong organization & presentation skills
  • Attention to detail to drive profitability
  • Ability to think strategically about the personal impact to the client's long-term business strategy
  • Team-oriented peer, with a thirst to compete to be the most valuable player


WHAT WE COMMIT TO YOU:

Industry-leading compensation with aggressive residual, uncapped commissions. Unsurpassed training, nationally ranked growth opportunities and our insanely awesome culture.

  • Territory development with Targeted Company opportunities
  • Strategic, pre-screened lead generation supported by multiple internal/external parties
  • A competitive starting BASE SALARY with performance-based increases
  • Residual, uncapped monthly commission
  • Monthly/Quarterly/Regional contest with great reward$$$
  • Fast track bonuses for quality deals your first year while ramping up
  • The compensation plan allows top performers to earn an annual six-figure income within 18 - 24 months
  • Nationally recognized sales training
  • Ongoing sales & management support
  • Progressive Advancement opportunity and national career mobility
  • Monthly auto & cell phone allowances
  • A comprehensive benefits package with medical, dental, vision coverage and a 401(k) program


WHY WORLDWIDE EXPRESS?

  • No. 1 largest privately held LTL broker in the country!
  • The largest non-retail authorized UPS® partner
  • More than 90,000 customers nationwide
  • Ranked a Top 10 Freight Brokerage Firm by Transport Topics for the past 5 years
  • Ranked a Top 50 Logistics firm globally by Transport Topics for the past 5 years
  • Nationally ranked/known for culture, training and career growth


WHO ARE WE?

Quite simply, we make shipping simple. Worldwide Express offers customers a comprehensive solution for their shipping needs, whether it be small package, less-than-truckload or full truckload. We are a local partner for your global supply chain, providing consultative service from more than 125 offices across the nation. Through our relationship with UPS® and a highly selective carrier portfolio, we provide our customers with a breadth of shipping options unmatched in the 3PL field.


Worldwide Express has a strategic partnership with UPS for light package, domestic and international shipping to penetrate the small to medium size business sector. As UPS's largest business partner in North America our sales teams do what they do best, which is providing solutions to a C-Level executive while letting UPS do what they do best, deliver more packages on time than anyone else. In addition to our relationship with ups WWE has alliances with over 65 LTL, Domestic Air Freight, and International Air Freight carriers. WWE provides tailored services and individualized shipping solutions to fit the need of any small to medium sized business customers.


Worldwide Express is an Equal Opportunity Employer. Worldwide Express Operations, LLC and WWEX Franchise Holdings, LLC (collectively “Worldwide Express”) strives to make employment decisions on the basis of merit, seeking the most qualified individuals in every job. All qualified applicants will receive consideration for employment without regard to race, color, religion, gender, pregnancy, gender identity or expression, sexual orientation, marital status, national origin or ancestry, genetics, disability, age, veteran status, or other status protected by law. All employment decisions will be based on valid job requirements or other legitimate, non-discriminatory reasons. Worldwide Express offers reasonable accommodations for individuals with disabilities in the job application and hiring process. If you would like to request such an accommodation, please contact the Human Resources Director of Worldwide Express.

Not Specified
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2nd Shift Production Supervisor
✦ New
Salary not disclosed
Chelsea, MA 14 hours ago

Job Description

JOB TITLE: Production Supervisor

Reports to: Manufacturing Manager or Lead Supervisor


SUMMARY: Kayem’s production supervisor is responsible for managing and coordinating the work of production teams to ensure efficient manufacturing operations and quality food production in a safe and cost-effective way to achieve performance targets. The person in this key role is responsible for overseeing production schedules, maintaining compliance with safety, quality, policy and applicable laws and standards, and driving continuous improvement initiatives. The supervisor will provide leadership in hiring, training, performance management, and employee development, ensuring a positive and productive work environment. Creates and maintains a culture of safety.


ESSENTIAL DUTIES AND RESPONSIBILITIES:


Production Management and Operations Oversight

•Ensures compliance with product quality, safety, and regulatory requirements.

•Develops and executes operational schedules to meet production targets to ensure customer orders are produced on time and in full.

•Plans for and ensures appropriate staffing levels are met.

•Monitors workflow, machine utilization, and team performance to maximize operational efficiency.

•Reviews production reports, identifies gaps, and implements solutions to improve performance.

Leadership and Team Development

•Leads, motivates, and develops team members to achieve production goals.

•Serves as the primary resource for employee questions, concerns, and performance-related matters.

•Provides coaching, feedback, and training to enhance individual and team effectiveness and team engagement.

•Conducts regular team meetings to review past results, address issues, and drive continuous improvement.

•Ensures safety training is conducted and completed by all team members.

Compliance and Continuous Improvement

•Ensures adherence to company policies, food safety protocols, and industry regulations.

•Promotes a culture of continuous improvement, employee engagement, and team collaboration.

•Develops and enforces standard operating procedures (SOPs) to maintain consistency and efficiency.


Communication and Reporting


•Communicates effectively with production teams, management, and cross-functional departments including maintenance, quality assurance, and safety teams.

•Maintains accurate records of production data, compliance activities, and operational metrics.


SKILLS AND COMPETENCIES


•Leadership: Ability to influence and inspire teams to meet organizational goals

•High sense of urgency

•Employee Development and Coaching: Motivates, trains, and supports team members.

•Operational Effectiveness: Strong problem-solving skills to manage daily production activities and changing priorities. Ability to anticipate adverse scenarios and provide contingency plan recommendations.

•Strong ability to interpret safety guidelines, operating procedures, and compliance regulations.

•Proficient in data analysis and reporting to drive informed decision-making.

•Bilingual skills in English and Spanish, Portuguese or French are a plus.

•Basic proficiency in Microsoft Office and manufacturing software.

•Ability to present functional specifications to the IT department when needed.

•Ability to read, write, and perform mathematical calculations, such as machine speeds and production rates.


EDUCATION and/or EXPERIENCE:


•High school diploma or equivalent. College degree preferred.

•1-3 years of supervisory experience in a manufacturing environment, preferably in food production.

•Equivalent combinations of education and experience will be considered.


WORK ENVIRONMENT:


The work environment characteristics described here are representative of those an employee encounters while performing the essential functions of this job. While performing the duties of this job, the employee is regularly exposed to refrigerated and wet conditions.


The noise level in the plant is usually loud.


Physical requirements including standing and walking for extended periods, climbing stairs regularly and lifting moderate weights.


PHYSICAL DEMANDS:


The physical demands described here are representative of those that must be met by an employee to successfully perform the essential functions of this job. Reasonable accommodations may be made to enable individuals with disabilities to perform the essential functions.

While performing the duties of this job, the employee is regularly required to use hands to finger, handle, or feel objects, tools, or controls; reach with hands and arms; and talk or hear. The employee is occasionally required to stand, walk, sit climb or balance, and smell.

The employee must regularly lift and/ or move up to 25 pounds and occasionally lift up to 50 pounds.


Pay Range


The base pay range for this role is $70K-$80K USD/annually.


The listed salary range represents Kayem Foods’ good faith estimate for this position and represents the minimum and maximum for new hire pay ranges.


Ranges are reviewed on a regular basis. An employee’s rate of pay within the range is determined by their qualifications, relevant experience, and demonstrated performance over time. In addition to those factors, we believe in the importance of pay equity and consider internal equity of our current team members as a part of any final offer. Hiring at the maximum of the range would not be typical to allow for future and continued wage growth. This position is eligible for our comprehensive benefits package and is eligible for an annual wage review. Kayem Foods complies with all federal, state, and local minimum wage laws.

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Production Supervisor
✦ New
Salary not disclosed
Melrose, MA 14 hours ago

Production Supervisor – Aerospace


$45 - $48 per hour + Excellent Benefits Package


Melrose, MA


Are you a Production Supervisor or Foreman, from an Aerospace background, looking to step up in to a Production Managers position?


This is an excellent opportunity to receive on the job training to develop your leadership skills whilst putting your own stamp on the business and overseeing a wide range of manufacturing processes.


This is a great time to join this niche manufacturer as they continue to work on innovative projects for their loyal customer base.


On offer is a varied role where you will be responsible for managing the machining, welding, painting, assembly and shipping teams. This is a fast paced role where you will work closely with clients and have the autonomy to implement new processes.


This role would suit an experienced Assembler, who wants to receive on the job training to develop as a Production Manager with a highly successful company where you will lean a wide range of new manufacturing processes.


The Role:


*Production Manager

*Overseeing machining, welding, painting, assembly and shipping processes

*Working closely with customers and implementing new bespoke processes


The Candidate:


*Experienced Production Supervisor / Foreman

*Aerospace background

*Wants on the job training and to progress as a manager

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Senior Transportation Manager
✦ New
Salary not disclosed
Boston, MA 14 hours ago

About the Role


A well-established leader in the food distribution and logistics industry is seeking a Senior Transportation Manager to oversee daily transportation operations across the Greater Boston region. This role is responsible for ensuring the safe, efficient, and compliant delivery of goods to clients while managing a large commercial fleet and team of professional drivers.


The ideal candidate will bring strategic leadership, hands-on operational expertise, and a strong focus on safety, compliance, and continuous improvement.


Key Responsibilities


· Oversee end-to-end transportation operations, including routing, dispatch, compliance, and fleet maintenance.

· Lead and develop a team of 100+ commercial drivers and transportation support staff.

· Ensure adherence to DOT, state, and federal regulations, maintaining up-to-date driver qualification and safety records.

· Implement and maintain preventive maintenance programs and accident-reduction initiatives.

· Analyze transportation data to identify trends, optimize routes, and improve efficiency.

· Manage relationships with vendors and cross-dock locations to ensure service reliability and cost control.

· Conduct training, driver road tests, audits, and performance evaluations.

· Approve payroll, manage employee relations, and oversee personnel files.

· Lead safety meetings and report key operational and safety metrics to senior leadership.


Qualifications


· Minimum 7 years of transportation or logistics management experience, preferably within distribution or foodservice.

· Bachelor’s degree in Business, Supply Chain, or a related field.

· Strong knowledge of DOT regulations, IFTA, HUD tax laws, and driver hours of service.

· Proficient in routing and GPS tracking systems (experience with Ortec preferred).

· Skilled in data analytics, reporting, and use of Microsoft Office Suite.

· Excellent communication and interpersonal skills; bilingual in English and Spanish required.

· Demonstrated ability to manage large teams and promote a strong culture of safety and accountability.


Competencies


· Strategic leadership and decision-making.

· Strong sense of integrity, reliability, and professionalism.

· Ability to manage complex logistics in a fast-paced environment.

· Calm under pressure with a collaborative, solutions-driven mindset.


Work Environment & Schedule


· Requires the ability to lift 50+ lbs. and perform active duties as needed.

· Must be available for extended hours, weekends, and holidays as business needs dictate.


Why This Opportunity


This confidential employer offers a stable, growth-oriented environment with opportunities for professional advancement. The selected candidate will play a pivotal role in shaping transportation strategy, enhancing safety performance, and leading a high-performing team.


Competitive compensation and benefits package included.


Take the Wheel and Lead the Way


If you’re a proven transportation leader with a passion for operational excellence and safety, we invite you to apply confidentially today.

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Audio Visual Technician
✦ New
Salary not disclosed
Boston, MA 14 hours ago

2 - 6 months contract


Description

Maintains an inventory in order to ensure availability of audiovisual equipment and supplies. Operates and maintains audiovisual equipment, including lights, sets, and staging, television cameras, computerized slide projectors, and recording and editing machines.

The Media Technician will be responsible for the check-in and check-out transactions in the Production Equipment Room and oversee student workers whose primary responsibility is to aid in the equipment transactions.

Essential Function 1: 60% Maintain equipment inventory and facilitate the reservation process.

Essential Function 2: 20% Assist students and faculty with various audio-visual technology.

Essential Function 3: 20% Work with the Field Production Services Manager to continually improve the processes and procedures that patrons use.

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