Jobs in Bedford, MA

Position Summary:

The Associate Director, Quality Control will be responsible for providing strategic, scientific, and operational leadership for the development, qualification, validation, and lifecycle management of analytical methods supporting Upstream Bio’s lead program verekitug. This role will manage and execute GMP quality control (QC) activities directly related to batch release for clinical trial material supply. The leader in this role must assure that quality controls for investigational new drugs (investigational medicinal products) meet all quality requirements, regulatory standards, and meet continuous clinical supply and delivery expectations. The Associate Director will report to Senior Director of Analytical and serve as a key partner to Quality, CMC, Regulatory, and cross-functional teams. This individual will provide technical guidance and business acumen to ensure execution of analytical activities for late-stage programs through BLA/MAA submission, approval, and commercial launch.

Key Responsibilities:

• Author, review and approve analytical method procedures/SOPs
• Author, review and approve analytical method transfer/qualification/validation protocols and reports
• Manage external CDMOs and CROs to execute Development and GMP release and stability testing of Drug Substance and Drug Product in a compliant-manner
• Establish and manage reference standard and critical reagent programs
• Participate in the laboratory quality system activities such as internal audits, writing standard operating procedures, and documentation review.
• Perform data verification and audits in order to ensure accuracy of data and analytical processes.
• Ensure compliance with company policies and SOPs as well as global health authority guidelines.
• Create, analyze, verify, and approve QC data such as method validation, release and stability, results, reports, and Certificates of Analysis (COAs).
• Generate, review, and revise specifications, SOPs, and other QC laboratory and testing documentation.
• Lead Out-of-Specification (OOS), Out-of-Trend (OOT), and Deviation investigations related to the QC laboratory and ensure effective corrective and preventive actions (CAPAs) are implemented.

Qualifications:

• Experience in stability study performance/evaluation and/or knowledge/familiarity with USP/compendial testing is helpful.
• Excellent verbal and written communication/interpersonal skills, problem-solving skills, organizational skills, and the ability to work in a diverse team environment are essential.
• Proficiency with Microsoft software (Word / EXCEL / PowerPoint), Stability software and statistical analysis/trending to support shelf life and labeling is expected.

Knowledge and skills (general and technical) preferred:

• Broad background, strong comprehension, and demonstrated skills in analytical methods development/validation/transfer/similar, reference standards characterization/structural elucidation, and unknown identification.

Education level and/or relevant experience required:

• Bachelor’s degree in a scientific or allied health field (or equivalent degree) and 10+ years of demonstrated success in leading cross-functional teams and managing projects along with 7+ years relevant analytical experience in a cGMP-compliant pharmaceutical laboratory environment. Any ASQ or other certifications is a plus.

About Upstream Bio:

Upstream Bio is a public company based in Waltham, MA. We are developing verekitug, the only known antagonist currently in development that targets the receptor for Thymic Stromal Lymphopoietin (TSLP). We have advanced this highly potent monoclonal antibody into separate Phase 2 trials for the treatment of severe asthma and chronic rhinosinusitis with nasal polyps (CRSwNP) and plan to initiate development in chronic obstructive pulmonary disease (COPD). Our experienced team is committed to maximizing verekitug’s unique attributes to address the substantial unmet needs for patients underserved by today’s standard of care. Learn more about us at .

Compensation

Target Salary Range: $176,400 - $215,600

*Base Compensation for this role will depend on a number of factors including a candidate’s qualifications, skills, competencies, and experience. Base pay is only one component of the company’s total rewards package. All regular employees are also eligible for the corporate bonus program or the incentive compensation program (if applicable), as well as equity. Additional benefits include health care, vision, dental, retirement, PTO, etc.

Sr. Quality Control & Sample Management Specialist

Our client is looking for an experienced QC and sample management professional to support high‑quality data generation within our Translational DMPK and Clinical Pharmacology team. This role ensures accuracy, compliance, and smooth sample lifecycle management across internal and external studies.

Responsibilities

• QC review of bioanalytical data (LC‑MS/MS, ELISA, qPCR) and study documentation from internal teams and CROs
• Manage and review scientific documents in SharePoint
• Format internal reports and provide templates to CROs
• QC review of packing slips, manifests, and critical reagent documentation
• Contribute to drafting and editing bioanalytical lab guidelines
• Routine QC of Electronic Lab Notebooks
• Audit finalized reports and maintain errata
• Use LIMS (LabVantage) for sample receipt, tracking, aliquoting, storage, shipping, and disposal

Requirements

• Bachelor’s degree in a scientific or healthcare field
• 5+ years QC experience in pharma, biotech, or CRO environments
• Proficiency with LIMS (LabVantage preferred) and electronic notebooks
• Strong understanding of GxP regulations
• Excellent attention to detail, communication, and organizational skills
• Proficiency in Microsoft Word, Excel, and PowerPoint
• Familiarity with bioanalytical assays is a plus

Medical Device Manufacturing Engineer Co-Op/Intern

On-site in Seaport, Massachusetts May-August (extension possible)

Amplitude Vascular Systems (AVS), an early-stage medical device company focused on safely and effectively treating severely calcified arterial disease, is seeking a Manufacturing Engineer-Co-Op to support our Operations team. This individual will work in a cross-functional role (Quality/Manufacturing/R&D) supporting the manufacturing of devices and associated instruments and technologies.

Key Responsibilities:

• Willing to work for cross functional teams (Operations, R&D and Quality & Regulatory.)
• Creating and modifying designs/drawings utilizing SolidWorks
• Testing prototype devices for functionality
• Supporting manufacturing with failure analysis
• Working in the lab, summarizing data, performing tests, and writing technical reports
• Participating and collaborating in team meetings and updates.
• Experience in Microsoft Word, Excel, and PowerPoint is essential
• Ability to work independently as well as take direction and complete tasks with or without help or supervision.

.Qualifications:

• In pursuit of Bachelor's degree in Mechanical, Industrial, Manufacturing, Electrical, or Biomedical Engineering. In Junior year or above.
• Self-motivated with an interest in medical devices
• 3-D modeling skills (NX Unigraphics & Solidworks Preferred)
• Experience using hand tools and performing mechanical testing
• Proven problem-solving capabilities
• Ability to communicate technical information
• Previous co-op completed in manufacturing at a medical device demonstrating skillsets listed above preferred.
• A minimum G.P.A. of 3.0
• Available to work full-time (40 hrs/week) May-August 2026
• This is an onsite position located in Waltham, MA.

AVS is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, age, national origin, or protected veteran status and will not be discriminated against on the basis of disability.

Join a leading pharmaceutical company’s Data Science team, where you’ll drive and lead advanced analytics across Marketing, Sales, and Access. As Associate Director (Or Sr Manager), A HIGH LEVEL INDIVIDUAL CONTRIBUTOR, you’ll lead strategic initiatives from predictive modeling and personalization to field force optimization, delivering scalable solutions that inform commercial decisions and enhance patient engagement. Deep experience in pharmaceutical marketing analytics is essential to translate brand strategy into actionable insights.

Keywords: MMM, Next Best Action, NLP, Data Science, HCP, GenAI

Location: Onsite 3 days a week in Cambridge, MA

Key Responsibilities

• Lead development and deployment of predictive models, segmentation, NLP, and GenAI tools to solve complex commercial challenges
• Translate pharmaceutical brand objectives into analytics frameworks across marketing, sales, and access
• Design and operationalize Next Best Action strategies to boost omnichannel engagement and HCP ROI
• Build and scale Patient 360 models and targeting algorithms for AI-driven lead generation
• Guide stakeholders through insight activation and integration into workflows
• Champion model governance, experimentation, and analytical rigor
• Collaborate with IT to develop ML Ops environments and productized solutions
• Manage external analytics partners and ensure alignment across data engineering, insights, and compliance

Who You Are

A strategic data scientist with strong business acumen, leadership presence, and deep experience in pharmaceutical marketing analytics. You thrive at the intersection of data and action, delivering measurable impact.

Qualifications

• 5+ years in analytics role within pharmaceutical industry
• Proven experience in pharmaceutical marketing analytics, including brand strategy, HCP engagement, and omnichannel optimization
• Expertise in NBA, MMM, supervised/unsupervised learning, A/B testing, time-series forecasting
• Success in marketing mix modeling, decision engines, and GenAI product design
• Proficient in Python, R, SQL, Snowflake; skilled in Power BI or Tableau
• Familiarity with APLD, PlanTrak, claims, and specialty pharmacy datasets
• Strong communicator with executive presence and cross-functional influence

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About Goodpath

Goodpath delivers integrative, AI-powered care for chronic conditions - blending 22 medical

disciplines into one personalized experience. We partner with employers, payors, and platforms

to reach members with industry-leading engagement and outcomes. We doubled ARR last year

and recently closed an $18M Series A to accelerate our next phase of growth.

The Role

We’re looking for a Chief of Staff to serve as the CEO’s right hand and keep the company

operating at its best. This is a high-leverage, cross-functional role: you’ll own the operating

rhythm of the company and step into whatever the business needs most – whether that’s

finance, hiring, investor relations, or special projects. The scope will evolve as Goodpath grows,

and so will you.

This is the right role for someone who thrives in ambiguity, moves fast, and takes pride in

making everyone around them more effective. You’ll report directly to CEO Bill Gianoukos.

What You’ll Do

• Own board and investor communications: prepare quarterly board materials, draft monthly investor updates, and manage investor relations
• Drive the company's operating cadence: keep the team aligned through goal-setting, accountability, and cross-functional coordination
• Lead core business functions as needed – this could include finance, operations, hiring, or other areas depending on where priorities lie at any given time
• Drive recruiting and people operations: oversee hiring pipelines, coordinate with hiring managers, and ensure a high-quality candidate experience
• Act as the CEO’s strategic partner: prep for key meetings, manage priorities, and serve as a trusted thought partner across the business
• Build team culture: plan offsites, all-hands meetings, and other touchpoints that keep a remote-first team connected
• Take on high-impact special projects that don’t fit neatly into any one function but are crucial in helping the business move forward

What You Bring to the Table

• 3–5 years of experience in operations, strategy, consulting, venture capital, or a similar high-output generalist role
• Financial fluency: you’re comfortable building financial models, managing a budget, and presenting to a board
• Extreme organizational skills and attention to detail – nothing falls through the cracks on your watch
• Strong written and verbal communication – you can draft an investor update or run a team meeting with confidence
• Comfort with ambiguity and unstructured environments – you don’t need a playbook to be effective
• Tech-savvy and eager to use AI and automation to work faster and smarter
• Healthcare or healthtech experience is a plus, but not required
• (Bonus points if you speak Greek…we have a team based in Greece)

You’ll Be Successful Here If You…

• Are a self-starter who takes ownership and doesn’t wait to be told what to do
• Get energy from wearing many hats and context-switching across finance, ops, people, and strategy in the same day
• Are not afraid to get your hands dirty – no task is beneath you if it moves the company forward
• Communicate with clarity and can distill complexity into action
• Want to build something meaningful at a company helping lead the future of GLP-1s and weight management

Compensation

• Base salary range: $100,000–$130,000 (dependent on experience)
• Meaningful equity in a hyper-growth Series A company
• Medical, dental, and vision insurance
• 401(k)
• Free Goodpath programs for you and your family

Why Join Us

• Join a mission-driven company at a clear inflection point
• Work directly with the CEO as his most trusted partner
• Shape the operating backbone of a rapidly scaling company
• Be part of a humble, high-performing team driven by meaningful impact
• Dynamic environment with room to learn, grow, and shape the company’s future

Vaxess is developing a pipeline of next-generation therapeutics on our novel micro-array patch platform. With only five minutes of wear-time on the skin, the Vaxess’ patch combines room temperature stability with simplified application to dramatically alter the way that drugs are delivered. Vaxess is committed to enabling products that are not only more effective, but also more accessible to patients around the world.

The Role

We are seeking a motivated and detail-oriented Research Associate with strong hands-on experience in chromatographic analysis to support QC release and stability testing. The successful candidate will perform routine cGMP QC testing using HPLC methods (RP-HPLC, SEC, IEX), Agilent HPLC systems, and additional supporting assays in a fast-paced, collaborative environment. This is a unique opportunity to be part of an emerging early-phase clinical company bringing innovative technology to the global market.

Key Responsibilities

• Perform routine QC release and stability testing using HPLC methods including RP-HPLC, SEC, and IEX.
• Prepare samples, operate Agilent HPLC systems, verify system suitability, and ensure analyses meet method and specification requirements.
• Execute complementary analytical assays such as UV-Vis, pH, surface tension, and mechanical tests.
• Maintain complete, accurate documentation in compliance with cGMP, ALCOA+, and data integrity requirements.
• Conduct routine instrument care (solvent flushes, column care, daily checks) and assist troubleshooting under supervision.
• Process and review chromatographic data in Agilent OpenLab CDS.
• Support method qualification, validation, and transfer activities by executing protocols and recording observations.
• Maintain calibration, maintenance, and service records for analytical instrumentation.
• Independently author method SOPs, analytical protocols, technical reports, and contribute to regulatory submissions.
• Collaborate cross-functionally with QC, Analytical Development, Process Development, Manufacturing, and Regulatory teams to enable program success.
• Maintain rigorous laboratory documentation and complete, audit-ready analytical records.
• Thrive in a fast-paced, cross-functional environment with excellent communication and organizational skills.

Qualifications

• Bachelor’s degree in Chemistry, Biochemistry, Chemical Engineering, or related field with 1–3 years of experience; or a master’s degree with relevant laboratory experience.
• Hands-on experience operating HPLC systems; Agilent systems and OpenLab CDS experience strongly preferred.
• Practical experience with chromatographic techniques including RP-HPLC, SEC, and IEX.
• Experience supporting QC release or stability testing in a GMP/GLP environment.
• Strong attention to detail and ability to follow SOPs precisely.
• Excellent documentation practices and understanding of data integrity.
• Strong organizational skills with the ability to manage multiple workflows and prioritize effectively in a fast-paced environment.
• Excellent verbal and written communication skills and comfort working within interdisciplinary teams.
• Commitment to collaborative work within interdisciplinary project teams.

At Vaxess, we’re bringing together exceptional talent to drive our product development forward. We value collaboration, curiosity, and a dynamic work environment. To apply, please submit your CV/resume to

Industry: Pharmaceuticals

Title: Senior Associate Scientist

Job ID: CAMB000127

Location: Cambridge MA

Duration: 09 months contract (+Possibility of extension)

Overview

The experienced Research Associate Scientist II, with a background in in vitro screening, will be part of our dynamic, fast-paced and interdisciplinary lead development team. Our mission is to advance Client RNAi therapeutic programs from target discovery through lead candidate selection. The Associate Scientist II will be technically skilled in molecular and/ or cell biology, and bring a rigorous, analytical approach to research.

This position is onsite and will be primarily located in Cambridge, MA.

Key Responsibilities

• Perform cell culture (iPSCs, primary cells, immortalized cell lines) to support the research needs of the group and high-throughput screening of siRNAs using qPCR and a variety of cell-based assays
• Execute day to day operations for RNASeq sample preparation, including: library preparation, QC and sequencing. Maintain sample tracking & records.
• Conduct assays that support in vivo studies (e.g. qPCR, ELISA) for the quantitative analysis of biomarkers or siRNA activity
• Support lab maintenance including equipment operation & maintenance , reagent inventory and reagent preparation
• Troubleshoot technical problems and participate in the continuing development and optimization of existing and new protocols.
• Utilize instrumentation and robotics to aid in high throughput (384-well) screening.
• Adapts well to the changing platform needs, in workflow, projects and other tasks as required by the platform.

Qualifications

• A BS in a biological science with at least 2 years of hands-on laboratory experience in cell or molecular biology are required
• Experience in cell culture and purification/quantification of nucleic acids/protein, including qPCR
• Experience with NGS workflow is desired
• Experienced with laboratory automation including liquid handling systems such as Perkin Elmer JANUS, Beckman i7 or other systems.
• The candidate should be intensely detail oriented, highly motivated, capable of managing multiple projects simultaneously, desire to drive innovation, and willingness to learn
• We particularly seek someone who is detail oriented and who will flourish in a goal-driven team environment under tight deadlines.
• Excellent interpersonal skills with the ability to work well with others in a dynamic and highly collaborative environment.

Comment Must-Have Skills/Experience

• Cell culture (including iPSCs, primary cells, immortalized lines)
• Experience with qPCR and other cell-based assays
• At least 2 years of hands-on lab experience Nice-to-Have Skills
• Experience with RNA sequencing (RNASeq) – library prep, QC, and sequencing
• Familiarity with liquid handling systems/automation (e.g., PerkinElmer JANUS, Beckman i7)
• Exposure to NGS workflows
• Minimum Education Bachelor's degree in biology or related field Master's degree preferred, but not required Work Experience
• At least 2 years of lab experience (no fresh graduates)
• Needs to be comfortable working independently and multitasking in a fast-paced lab environment Soft Skills / Culture Fit - Proactive and dependable
• Able to work independently and figure things out without constant direction
• Easygoing but motivated and ambitious
• Strong communication and collaboration skills

Must-Have Technical Skills:

• Complex in vitro experience
• iPSC experience
• 3D models
• Mammalian cell culture
• CRISPR
• qPCR
• RNA work
• Transfection

Company Description

Boston Hand to Shoulder is a leading orthopaedic practice specializing in upper extremity conditions—from hand to shoulder—as well as sports-related injuries, including the lower extremity. Serving over 1,500 patients across the Greater Boston area and New England, we provide expert care to individuals of all ages and activity levels, including professional athletes. Our team of nationally recognized orthopaedic specialists is dedicated to delivering holistic and compassionate care, prioritizing prompt appointments within 48 hours. Known for our clinical expertise, teaching, and research, we take pride in being a trusted provider of specialized care and second opinions.

Role Description

This is a part-time, on-site role for a Practice Assistant located in Newton, MA. The Practice Assistant will provide administrative and clerical support to ensure smooth day-to-day operations within the orthopaedic practice. Responsibilities include managing patient appointments, maintaining records, handling phone communications, providing customer service, and assisting with general office duties. Interaction with patients, physicians, and staff will be a key aspect of this role, requiring professionalism and excellent interpersonal skills.

Qualifications

• Strong clerical skills, including data entry, filing, and managing records
• Experience in administrative assistance to support daily operational needs
• Excellent phone etiquette and communication abilities
• Outstanding customer service skills with a patient-focused attitude
• Familiarity with medical terminology and healthcare operations is a plus
• Proficiency in scheduling systems and office software
• High school diploma or equivalent; additional education or certifications are a plus
• Ability to work effectively in a collaborative, team-oriented environment

Patient Service Coordinator/Administrative Coordinator (Surgical Specialties)

Location: Newton, MA (Fully On-site)

Type: Temp-to-Perm (6-month initial contract)

Schedule: Monday – Friday, 8:00 AM – 4:30 PM (40 hours/week)

Pay Rate: $20.00 – $25.00 per hour (commensurate with experience).

About the Role

We are is seeking a professional, high-energy Administrative Coordinator to serve as the face of our Surgical Specialties department. Operating at the front desk, you will be the primary point of contact for patients, ensuring a seamless experience from check-in to clinical scheduling.

As a member of the network, you will play a vital role in a community-focused environment backed by the resources of world-class medical institutions.

Key Responsibilities

• Patient Coordination: Act as the department "gatekeeper," managing front-desk check-ins and welcoming patients with empathy and professionalism.
• Clinical Scheduling: Manage complex appointment scheduling for surgeons and specialists using Epic.
• Communication: Handle high-volume phone lines, screen inquiries, manage voicemails, and relay urgent messages to clinical staff.
• Administrative Support: Manage referrals, verify health insurance coverage, and collect patient co-payments.
• Records Management: Organize and maintain accurate, confidential patient records and departmental logs.

Qualifications

• Education: High School Diploma or equivalent required; Associate’s degree preferred.
• Experience: * Minimum of 2 years in a medical office environment preferred.
• Must Have: Previous front-desk or customer service experience in a healthcare setting.
• Preferred: Experience specifically supporting surgeons or clinical scheduling.
• Technical Skills: * Epic EMR experience is highly preferred (specifically for scheduling and co-pay collection).
• Proficiency in Microsoft Office Suite (Word, Excel, Outlook).
• Soft Skills: Ability to multi-task in a high-volume outpatient setting, strong organizational skills, and a "patient-first" attitude.

Compensation & Benefits

• Pay Rate: $20.00 – $25.00 per hour (commensurate with experience).
• Permanent Conversion: Potential for permanent placement with a salary range of $51,000 – $60,000 upon conversion.
• Perks: On-site parking available (one-time $15 registration fee).

Equal Opportunity Employer: Race, Color, Religion, Sex, Sexual Orientation, Gender Identity, National Origin, Age, Genetic Information, Disability, Protected Veteran Status, or any other legally protected group status.

At Randstad, we welcome people of all abilities and want to ensure that our hiring and interview process meets the needs of all applicants. If you require a reasonable accommodation to make your application or interview experience a great one, please contact

Pay offered to a successful candidate will be based on several factors including the candidate's education, work experience, work location, specific job duties, certifications, etc. In addition, Randstad offers a comprehensive benefits package, including: medical, prescription, dental, vision, AD&D, and life insurance offerings, short-term disability, and a 401K plan (all benefits are based on eligibility).

This posting is open for thirty (30) days.

It is unlawful in Massachusetts to require or administer a lie detector test as a condition of employment or continued employment. An employer who violates this law shall be subject to criminal penalties and civil liability.

Vaxess is developing a pipeline of next-generation therapeutics on our novel micro-array patch platform. With only five minutes of wear-time on the skin, the Vaxess’ patch combines room temperature stability with simplified application to dramatically alter the way that drugs are delivered. Vaxess is committed to enabling products that are not only more effective, but also more accessible to patients around the world.

The Role

We are seeking a talented, collaborative, and highly motivated individual with expertise analytical methods highly focused on HPLC and QC operations to join our core team of scientists and engineers. The Senior Scientist will execute Quality Control testing, and associated operations and contribute to analytical testing to ensure compliance with cGMP requirements. This is a unique opportunity to be part of an emerging early-phase clinical company bringing innovative technology to the global market.

Key Responsibilities

• Lead the design, development, optimization, and execution of HPLC-based analytical methods (e.g., RP-HPLC, SEC, IEX) to support in-process, release, and stability testing.
• Develop, qualify, validate, and characterize GMP-compliant purity, SEC, and content methods for intermediates and drug products, with a strong emphasis on chromatographic workflows.
• Author and execute cGMP method qualification and validation protocols, prepare reports, and perform/oversee routine QC testing.
• Serve as Subject Matter Expert for chromatography methods during investigations of deviations, OOS/OOT events, assay failures, and other non-conformance issues.
• Provide technical leadership in HPLC troubleshooting, instrument maintenance coordination, data integrity practices, and chromatographic data review.
• Independently author method SOPs, analytical protocols, technical reports, and contribute to regulatory submissions.
• Maintain rigorous laboratory documentation and complete, audit-ready analytical records.
• Collaborate effectively with QC, Manufacturing, Process Development, and Regulatory teams to enable program success across phases.
• Thrive in a fast-paced, cross-functional environment with excellent communication and organizational skills.

Qualifications

• Ph.D. in Analytical Chemistry, Biochemistry, or related field with a minimum of 4 years (10 years for Senior Scientist) in the biotech/pharmaceutical industry; or M.S. with commensurate experience.
• Demonstrated in-depth expertise in HPLC, including method development, troubleshooting, system suitability design, chromatographic theory, and data interpretation.
• Hands-on experience with multiple chromatographic techniques (RP-HPLC, SEC, IEX, affinity, gradient optimization, detector setup/maintenance).
• Proven success developing and validating GMP analytical methods and supporting GMP operations.
• Experience with complementary analytical techniques such as UV-Vis, LC-MS, CE, ELISA, or other functional assays is beneficial.
• Experience working in a QC or cGMP laboratory environment with strong understanding of data integrity requirements (ALCOA+).
• Strong organizational skills, precision in documentation, and ability to manage multiple analytical workflows simultaneously.
• Excellent oral and written communication skills.
• Commitment to collaborative work within interdisciplinary project teams.

At Vaxess, we’re bringing together exceptional talent to drive our product development forward. We value collaboration, curiosity, and a dynamic work environment. To apply, please submit your CV/resume to .