Engineering Structures Login Jobs in Pasadena, CA

140 positions found — Page 9

Continuous Improvement Plant Director
Salary not disclosed

About the Organization:

We are in the middle of a true operational transformation — moving from tribal knowledge and reactive processes to a disciplined, data-driven, standardized manufacturing environment. This is not “check-the-box Lean.” We are building systems, accountability, and a sustainable culture of continuous improvement. If you are hands-on, execution-focused, and motivated by measurable results, this is an opportunity to drive real change.


Position Overview:

The Continuous Improvement Plant Director will lead high-impact operational improvement initiatives across manufacturing. This role goes beyond analysis — you will implement solutions, train teams, standardize processes, and ensure improvements are sustained. High visibility role working cross-functionally with Production, Quality, Engineering, and Supply Chain, with direct visibility to senior leadership.


Responsibilities:

  • Lead continuous improvement and lean manufacturing initiatives
  • Identify and eliminate operational bottlenecks (quality escapes, rework, prep time, inefficient assembly, material flow issues, etc.)
  • Lead Lean and Six Sigma (DMAIC) projects delivering measurable improvements in cost, quality, and cycle time
  • Drive root cause analysis and implement sustainable corrective actions
  • Convert tribal knowledge into Standard Work, SOPs, and clear work instructions and help move the operation toward a paperless, analytics-driven environment
  • Support development of scalable, repeatable processes
  • Develop and track KPIs (scrap, rework, downtime, OTD, cycle time)
  • Analyze shop floor data and present actionable insights to leadership
  • Measure and report savings in dollars, hours reduced, and risk mitigation
  • Support ERP improvements, system integrations and implement visual management tools and structured shop floor controls
  • Implement digital tools (Power BI, Excel, Power Automate, digital checklists)
  • Deliver hands-on Lean/CI training to operators, leads, and supervisors
  • Lead Kaizen events, Gemba walks, and cross-functional improvement workshops
  • Reinforce accountability and continuous improvement mindset at all levels


Requirements:

  • Bachelor’s degree in Industrial, Manufacturing, Mechanical Engineering, or related field
  • 7+ years of hands-on manufacturing engineering or continuous improvement experience
  • Strong knowledge of Lean Manufacturing (5S, VSM, SMED, Poka-Yoke, Visual Management) and Six Sigma (DMAIC, root cause analysis)
  • Experience developing standard work, driving real improvements, measurable cost savings, cycle time reductions and shop floor digital tools
  • Bilingual English/Spanish Required


Nice to Have:

  • Six Sigma Black/Green Belt or Lean certification
  • Background in Aerospace, heavy fabrication, or complex assembly preferred
  • Experience leading ERP transitions, implementing MES and digital work instruction systems
  • Knowledge of ISO 9001 or AS9100 a Huge Plus
  • Demonstrated track record of measurable operational improvements
  • Self-starter who takes ownership, stands behind data-driven decisions, and thrives in a hands-on environment
Not Specified
Occupational Therapist Per Diem 777001
Salary not disclosed
Pasadena, CA 1 week ago
When you join the Huntington Hospital team, you are aligning yourself with an organization whose values drive our philosophy of compassionate community care. Over the past 129 years, we’ve grown from a small 16-bed hospital to a nationally recognized healthcare leader with 619 beds. As part of our commitment to providing equitable, high-quality care to all members of our community, we embrace differences and work hard to create a place of belonging for our patients and our employees. When you join the Huntington family, you’ll be empowered to enact change that continuously improves our ability to deliver world-class care, with kindness and dignity, to all who need it.

** Internal Workers – Please log into your Workday account to apply **

Huntington Hospital Employee Login

Expectations:

Evaluates, plans and administers treatment for disabilities, injuries and diseases in accordance with a physician's order. Responsible for coordination of care to meet identified Occupational Therapy needs of the patient/family; participates in the management of patient care to include identification of needs of Occupational Therapy intervention, discharge planning, resource identification, linking and scheduling patients with required services, monitoring care delivery, advocating for the patient, and evaluating outcomes, facilitating patient care across the health care continuum, and assists other team members with meeting patient needs. Is preceptor for related staff and students. Requires California State Occupational Therapist License.
This is a per diem position which may require flexibility of hours and is eligible for overtime pay.

EDUCATION:
Graduate of an educational program for occupational therapists approved by the California Board of Occupational Therapy and accredited by the American Occupational Therapy Association’s Accreditation Council for Occupational Therapy Education (ACOTE).

EXPERIENCE/TRAINING:
Determined by patient care area. Minimum of one year related practice experience preferred.

LICENSES/CERTIFICATIONS:
Required:
Current unrestricted Occupational Therapist License issued by California Board of Occupational Therapy (CBOT)
Current Occupational Therapist Registered (OTR) issued by National Board for Certification in Occupational Therapy (NBCOT)
Current Physical Agent Modalities (PAM) Certification issued by State of California for working with modalities: specialized hand diagnoses patients, pediatrics, dysphagia
Current Basic Life Support Provider (BLS) issued by American Heart Association

SKILLS:
Successful completion of orientation.

Job Title: Occupational Therapist Per Diem_O/P Rehab

Department: O/P Rehab

Shift Duration: 8

Primary Shift: Days

Time Type: Part time

Location: 100 W California Blvd, Pasadena, CA 91105

Pay Range: The estimated base rate for this position is $49.54 - $70.75.

Additional individual compensation may be available for this role through differentials, extra shift incentives, bonuses, etc. Base pay is only a portion of the total rewards package, and a comprehensive benefits program is available for qualifying positions.

Not Specified
Occupational Therapist Per Diem - Certified Hand Therapist
🏢 Huntington Hospital
Salary not disclosed
Pasadena, CA 1 week ago
When you join the Huntington Hospital team, you are aligning yourself with an organization whose values drive our philosophy of compassionate community care. Over the past 129 years, we’ve grown from a small 16-bed hospital to a nationally recognized healthcare leader with 619 beds. As part of our commitment to providing equitable, high-quality care to all members of our community, we embrace differences and work hard to create a place of belonging for our patients and our employees. When you join the Huntington family, you’ll be empowered to enact change that continuously improves our ability to deliver world-class care, with kindness and dignity, to all who need it.

** Internal Workers – Please log into your Workday account to apply **

Huntington Hospital Employee Login

Expectations:

Evaluates, plans and administers treatment for disabilities, injuries and diseases in accordance with a physician's order. Responsible for coordination of care to meet identified Occupational Therapy needs of the patient/family; participates in the management of patient care to include identification of needs of Occupational Therapy intervention, discharge planning, resource identification, linking and scheduling patients with required services, monitoring care delivery, advocating for the patient, and evaluating outcomes, facilitating patient care across the health care continuum, and assists other team members with meeting patient needs. Is preceptor for related staff and students. Requires California State Occupational Therapist License.
This is a per diem position which may require flexibility of hours and is eligible for overtime pay.

EDUCATION:
Graduate of an educational program for occupational therapists approved by the California Board of Occupational Therapy and accredited by the American Occupational Therapy Association’s Accreditation Council for Occupational Therapy Education (ACOTE).

EXPERIENCE/TRAINING:
Determined by patient care area. Minimum of one year related practice experience preferred.

LICENSES/CERTIFICATIONS:
Required:
Current unrestricted Occupational Therapist License issued by California Board of Occupational Therapy (CBOT)
Current Occupational Therapist Registered (OTR) issued by National Board for Certification in Occupational Therapy (NBCOT)
Current Physical Agent Modalities (PAM) Certification issued by State of California for working with modalities: specialized hand diagnoses patients, pediatrics, dysphagia
Current Basic Life Support Provider (BLS) issued by American Heart Association

SKILLS:
Successful completion of orientation.

Job Title: Occupational Therapist Per Diem_O/P Rehab

Department: O/P Rehab

Shift Duration: 8

Primary Shift: Days

Time Type: Part time

Location: 100 W California Blvd, Pasadena, CA 91105

Pay Range: The estimated base rate for this position is $49.54 - $70.75.

Additional individual compensation may be available for this role through differentials, extra shift incentives, bonuses, etc. Base pay is only a portion of the total rewards package, and a comprehensive benefits program is available for qualifying positions.

Not Specified
CT Technologist
🏢 Huntington Hospital
Salary not disclosed
Pasadena, CA 1 week ago
When you join the Huntington Hospital team, you are aligning yourself with an organization whose values drive our philosophy of compassionate community care. Over the past 129 years, we’ve grown from a small 16-bed hospital to a nationally recognized healthcare leader with 619 beds. As part of our commitment to providing equitable, high-quality care to all members of our community, we embrace differences and work hard to create a place of belonging for our patients and our employees. When you join the Huntington family, you’ll be empowered to enact change that continuously improves our ability to deliver world-class care, with kindness and dignity, to all who need it.

** Internal Workers – Please log into your Workday account to apply **

Huntington Hospital Employee Login

Expectations:

Under limited supervision and as assigned by Area Coordinator to produce radiographs/scans for medical diagnosis. Involves positioning patients and adjusting equipment for proper exposure and for film development. Records pertinent information pertaining to the production of the radiograph/scan. Assists in the supervision of Radiology students. Maintains assigned work area in a neat and orderly condition. Use of the computer.
This position requires the ability to take on-call for patients requiring emergency procedures.
This position may require flexibility of hours.

EXPERIENCE/TRAINING:
One year experience as a Radiologic Technologist working in the area to be assigned (i.e. CT, MRI, Emergency/Portable/Surgery).

LICENSES/CERTIFICATIONS:
Required:
Current Certified Radiologic Technologist (CRT) issued by California Department of Public Health (CDPH)
Current Certified Radiologic Technologist (CRT) Fluoroscopy Permit issued by California Department of Public Health (CDPH)
Current American Registry of Radiologic Technologists (ARRT) certification issued by The American Registry of Radiologic Technologists
Current Venipuncture Certification issued by California Society of Radiologic Technologists (CSRT)
Current Basic Life Support Provider (BLS) issued by American Heart Association

SKILLS:
Knowledge of computers, anatomy, physiology, radiographic equipment, safety hazards common to Radiology equipment used, body mechanics, isolation procedures and body fluid precautions.

Job Title: CT Technologist

Department: CT Scanner

Shift Duration: 8

Primary Shift: Nights

Time Type: Full time

Location: 100 W California Blvd, Pasadena, CA 91105

Pay Range: The estimated base rate for this position is $44.94 - $68.54.

Additional individual compensation may be available for this role through differentials, extra shift incentives, bonuses, etc. Base pay is only a portion of the total rewards package, and a comprehensive benefits program is available for qualifying positions.

Not Specified
Pharmacist, Night Schedule
🏢 Huntington Hospital
Salary not disclosed
Pasadena, CA 1 week ago
When you join the Huntington Hospital team, you are aligning yourself with an organization whose values drive our philosophy of compassionate community care. Over the past 129 years, we’ve grown from a small 16-bed hospital to a nationally recognized healthcare leader with 619 beds. As part of our commitment to providing equitable, high-quality care to all members of our community, we embrace differences and work hard to create a place of belonging for our patients and our employees. When you join the Huntington family, you’ll be empowered to enact change that continuously improves our ability to deliver world-class care, with kindness and dignity, to all who need it.

** Internal Workers – Please log into your Workday account to apply **

Huntington Hospital Employee Login

Expectations:

Supervises and coordinates the delivery of pharmaceutical care to patients of the hospital. Pharmaceutical care is the evaluation, distribution, and monitoring of prescribed therapy which provide positive patient outcomes. Maintains current California Pharmacist license. This position may require flexibility of hours.

EDUCATION:
Doctor of Pharmacy degree from an accredited school of pharmacy preferred. Diploma or transcripts on highest degree earned required.

EXPERIENCE/TRAINING:
Two years of experience in a progressive hospital pharmacy practice is preferred.

LICENSES/CERTIFICATIONS:
Required:
Current unrestricted Registered Pharmacist license (RPH) issued by California State Board of Pharmacy
Current Basic Life Support Provider (BLS) issued by American Heart Association

SKILLS:
Requires mobility to be able to respond quickly to Code Rapid Response and Code Blue situations and to be able to transport the emergency pharmacy medication box.

Job Title: Pharmacist, Night Schedule

Department: Pharmacy

Shift Duration: 10

Primary Shift: Nights

Time Type: Full time

Location: 100 W California Blvd, Pasadena, CA 91105

Pay Range: The estimated base rate for this position is $76.27 - $116.31.

Additional individual compensation may be available for this role through differentials, extra shift incentives, bonuses, etc. Base pay is only a portion of the total rewards package, and a comprehensive benefits program is available for qualifying positions.

Not Specified
Senior Director of Operations
Salary not disclosed
South El Monte, CA 2 weeks ago

A leading Space and Defense manufacturer in Los Angeles is seeking a Director of Operations to lead a technically complex production environment specializing in large, lightweight metallic structures and assemblies serving aerospace, missile, and hypersonic markets.


This facility focuses on metallic forming, precision forming, advanced spin forming, CNC machining, fabrication, and assembly integration. The Director of Operations will own full site-level operational performance and P&L accountability, driving production discipline across multi-step manufacturing routings involving machining, forming, welding coordination, heat treat, finishing, and final assembly.


This is a hands-on manufacturing leadership role for an operator who understands large-part CNC machining, tight-tolerance metallic components (aluminum highly desired), and the execution rigor required to scale throughput while improving margin performance.


Responsibilities:

  • Lead all production operations across CNC machining, metallic forming, spin forming, fabrication, finishing, and assembly.
  • Establish structured daily production management cadence to improve schedule adherence, throughput, and flow.
  • Drive performance across large gantry milling, 3-axis and 5-axis machining environments.
  • Optimize complex manufacturing routings spanning machining, deburring, forming, welding coordination, heat treat, and integration.
  • Own site-level P&L performance, improving labor efficiency, equipment utilization, and cost control.
  • Implement and sustain Lean manufacturing systems including 5S, SMED, TPM, and OEE-based performance management.
  • Improve spindle utilization, setup reduction, preventative maintenance discipline, and machining efficiency.
  • Partner cross-functionally with Engineering, Quality, and Program Management to ensure production readiness and operational scalability.
  • Build and lead high-performance manufacturing teams with strong shop-floor engagement.


Qualifications:

Required

  • 10+ years of progressive leadership experience in aerospace or advanced CNC manufacturing environments.
  • 5+ years leading a machining-intensive manufacturing operation with full production accountability.
  • Experience producing large, tight-tolerance metallic components (aluminum strongly preferred).
  • Demonstrated oversight of 3-axis, 5-axis, and large gantry milling environments.
  • Proven P&L ownership within a manufacturing facility.
  • Experience managing complex multi-step production flows and downstream processes.
  • Strong working knowledge of Lean manufacturing systems and operational metrics (OEE, labor efficiency, cycle time, TPM).
  • ERP/MRP production planning proficiency.


Preferred

  • Experience in metallic forming, spin forming, or structural fabrication environments.
  • Background supporting aerospace, missile, or space-related programs.
  • Lean Six Sigma certification or formal continuous improvement leadership experience.


Salary: $180,000 - $220,000

Not Specified
Business Analyst / Product Manager (Healthcare Focus)
Salary not disclosed
Los Angeles County, CA 2 weeks ago
About the Role

We are seeking a Business Analyst / Product Manager to help translate business needs into well-designed, scalable products—primarily within the healthcare domain. This is a hybrid role ideal for someone who is analytically strong, curious, and eager to grow into broader product ownership and leadership responsibilities over time.

The ideal candidate is smart, adaptable, and motivated to learn, with enough healthcare exposure to understand industry context (e.g., payers, providers, data, compliance), but not necessarily a long tenure in product management. This role offers significant opportunity for growth.

Key ResponsibilitiesBusiness Analysis
  • Gather, analyze, and document business requirements from stakeholders
  • Translate business needs into clear functional requirements, user stories, and acceptance criteria
  • Analyze workflows, data models, and system interactions to identify gaps and improvements
  • Support solution design by working closely with engineering, data, and architecture teams
Product Management
  • Assist in defining product vision, roadmap, and priorities
  • Collaborate with stakeholders to balance business value, technical feasibility, and timelines
  • Own and refine product backlogs; participate in sprint planning and reviews
  • Support go-to-market planning, release coordination, and post-launch evaluation
  • Continuously identify opportunities to improve user experience and product outcomes
Cross-Functional Collaboration
  • Act as a bridge between business, technical teams, and leadership
  • Communicate clearly across technical and non-technical audiences
  • Support decision-making with data, analysis, and structured thinking
Required Qualifications
  • 2–5 years of experience in business analysis, product management, or a related role
  • Some experience or exposure to healthcare (payer, provider, health IT, analytics, compliance, or adjacent domains)
  • Strong analytical and problem-solving skills
  • Excellent written and verbal communication skills
  • Ability to learn quickly and adapt in a fast-moving environment
  • Comfortable working remotely and collaborating with distributed teams
Preferred Qualifications
  • Experience with healthcare data models, workflows, or standards (e.g., claims, eligibility, clinical data, FHIR, HL7)
  • Experience working with Agile/Scrum teams
  • Familiarity with product tools (Jira, Confluence, Azure DevOps, Productboard, etc.)
  • Technical curiosity (APIs, data platforms, analytics, or cloud systems)
What We’re Looking For
  • Someone intellectually curious who wants to grow into a senior product role
  • A self-starter who takes ownership and asks thoughtful questions
  • A team player who values clarity, structure, and impact
  • Someone who can evolve with the role as the product and organization scale


Not Specified
Business Systems Analyst / Strategist - Palantir Foundry
Salary not disclosed
Monrovia, CA 1 week ago

I hope you're doing well! We have an interesting, brand new Business Systems Analyst / Strategist working for a well-known company in Monrovia, CA. This role works in the company's IT Applications and Development group and will be playing a critical role in translating challenges into data-driven products.


In this role, the individual will be partnering closely with SMEs, business stakeholders, and Engineering teams to design, implement, and operate scalable data products for internal use using the Palantir Foundry platform. Palantir Foundry experience is highly preferred, but we will also consider individuals who have worked in other platforms including Databricks, DataWalk, Snowflake, Alteryx, etc.


This individual will work to integrate Foundry into existing systems and workflows to maintain data integrity, workflows, etc. We are seeking someone with 2 - 5 years of experience in a similar role.


This is a full-time, salaried position working onsite in Monrovia. I look forward to working with you!


Essential Responsibilities

  • Partner with business stakeholders and Forward Deployed Engineering teams to build impactful data products
  • Is Admin for the platform and oversees the support of critical workflows operations
  • Oversee solution design, product implementation, and end-to-end program execution
  • Collaborate with IT and Forward Deployed Engineering teams to integrate Foundry into existing systems and workflows to maintain data integrity and workflows.
  • Design and build customized workflows that address specific business needs


Qualifications

  • Bachelor’s degree preferred
  • Minimum of 2-5 years of experience as a Palantir or in a comparable forward-deployed, client-facing technical role
  • Minimum 2-3 years building data products and workflows
  • Minimum 2-3 years Palantir Foundry experience, including use case design and implementation
  • Experience administering Palantir Foundry instance strongly preferred.
  • Strong proficiency in data engineering and data analysis tools such as Python, Spark, and SQL. Additional Data Science experience strongly preferred
  • Exceptional communication skills with a proven ability to manage and influence diverse stakeholders
  • Demonstrated ability to understand critical user questions, identify pain points, and optimize product usage
  • Proven track record of collaborating effectively with engineering teams to deliver complex, cross-functional projects
  • Exceptional problem-solving skills, with strong creativity, analytical thinking, and attention to detail
Not Specified
Project Manager, New Product Launches
🏢 Counter
Salary not disclosed

Company: G2G Ventures Inc, PBC

Job Title: Project Manager, New Product Launches

Location: Hybrid – Santa Monica, CA (3 days per week in office)

Department: Product Development

Reports to: Director of New Product Launches

About Us:

We are a startup revolutionizing beauty with a purpose: create the industry standard of "clean." Our premium skincare, makeup, and body care formulations combine uncompromising safety, efficacy, and environmental responsibility. And our vision transcends products.

We are committed to inspiring confident women (and others) to recognize their collective power to create meaningful change. Our innovative community-commerce ecosystem connects customers, beauty enthusiasts, and loyalists, allowing each person to align with our brand in ways that authentically reflect their values and aspirations.

From our formulas to our advocacy efforts to our community connection, we lead clean.

About the Role:

The Project Manager, New Product Launches will drive the end-to-end execution of new product development and go-to-market initiatives. Reporting to the Director of New Product Launches, this role serves as the operational engine behind cross-functional product launches — ensuring timelines are met, stakeholders are aligned, risks are mitigated, and deliverables are executed with excellence.

This individual will manage the detailed workstreams required to bring products from concept through commercialization — partnering closely with Product Development, Operations, Supply Chain, Marketing, Creative, Sales, Finance, and external vendors.

The ideal candidate thrives in a fast-paced startup environment, is highly organized, and excels at turning strategy into action.

What You'll Do:

1. End-to-End Launch Management

• Build and manage comprehensive project timelines from concept to launch

• Define key milestones, dependencies, and critical paths

• Lead weekly cross-functional launch meetings and drive accountability

• Track risks, escalate issues proactively, and propose mitigation plans

• Ensure launches are delivered on time and aligned with business objectives

2. Cross-Functional Coordination

• Partner with Product Development on formulation, packaging, and testing timelines

• Collaborate with Operations and Supply Chain on forecasting, production, and inventory readiness

• Align with Marketing and Creative on campaign assets, messaging, and launch calendars

• Coordinate with Sales on retailer readiness, education tools, and sell-in timelines

• Ensure Finance alignment on costing, margin targets, and launch forecasts

3. Process & Operational Excellence

• Create and maintain standardized launch playbooks, templates, and tracking tools

• Improve workflows to increase efficiency and reduce time-to-market

• Maintain documentation including briefs, timelines, status reports, and post-mortems

• Support capacity planning and resource allocation across launch calendar

4. Vendor & External Partner Management

• Coordinate timelines with packaging vendors, contract manufacturers, testing labs, and creative agencies

• Track deliverables and hold partners accountable to agreed deadlines

• Support contract and SOW execution in partnership with leadership

5. Post-Launch Review & Optimization

• Lead post-launch retrospectives to identify wins and improvement areas

• Track launch performance metrics in partnership with Analytics and Sales

• Implement process improvements based on learnings

You'll Excel in This Role If You Are...

• Highly organized. You naturally create structure in ambiguity.

• Detail-oriented. Nothing slips through the cracks.

• Proactive. You anticipate risks before they become problems.

• Clear communicator. You drive alignment across diverse teams.

• Execution-driven. You love bringing ideas to life.

• Comfortable with pace. You thrive in dynamic, evolving startup environments.

What You'll Bring:

• 3–5 years of experience in project management, product development, brand operations, or related fields (beauty, CPG, or retail preferred)

• Proven experience managing cross-functional product launches

• Strong proficiency in project management tools (Asana, Monday, Jira, or similar)

• Excellent organizational and documentation skills

• Ability to manage multiple projects simultaneously with competing deadlines

• Strong interpersonal skills and ability to influence without authority

• Experience in beauty, skincare, or consumer goods strongly preferred

• Bachelor's degree or equivalent experience

Why This Role Is Exciting:

You'll play a pivotal role in shaping the future of a mission-driven beauty brand at a foundational stage. Your work will directly impact innovation, speed-to-market, and revenue growth. This is an opportunity to build scalable processes, influence cross-functional collaboration, and help define how clean beauty evolves in the market.

Counter is a people-powered movement that starts with those behind it. We're building a team that reflects the diversity of the communities we serve, where every individual is respected, supported, and empowered to thrive.

We know that different backgrounds, identities, and perspectives make us stronger, more creative, and better equipped to drive change. That's why we're committed to fostering an inclusive culture where everyone belongs.

Counter is proud to be an Equal Opportunity Employer. We do not discriminate based on race, color, religion, sex, sexual orientation, gender identity or expression, age, national origin, disability, veteran status, or any other legally protected status. We encourage all individuals to apply and join us in shaping a cleaner, more inclusive future for all.

Not Specified
In Vivo Pharmacology (Senior Research Assistant - Senior Associate Scientist Level)
🏢 Caltech
Salary not disclosed
Pasadena, CA 1 week ago

In Vivo Pharmacology (Senior Research Assistant - Senior Associate Scientist Level)

California Institute of Technology & Howard Hughes Medical Institute | Elowitz Lab

Full-time | Pasadena, CA (onsite) | 1-year term (renewable) | Start: March-April 2026 (flexible)


Our team in the Elowitz Lab at Caltech/HHMI is engineering therapeutic protein circuits, a new cancer-treatment modality at the intersection of synthetic biology and oncology. We’re looking for an in vivo oncology scientist (Senior Research Assistant to Senior Associate Scientist) to help expand and run the program’s translational in vivo engine. The role starts in an academic setting, with the option to transition into an early-stage startup in 2027.


Why therapeutic circuits?

Cancer therapies face a fundamental trade-off between effectiveness and precision, driving off-target toxicity, recurrence, and resistance. Therapeutic protein circuits address this by directly rewiring oncogenic mutations to cell death. Delivered as mRNA in lipid nanoparticles, these engineered proteins can distinguish cancer from normal cells and have shown tumor suppression in vivo. By design, these circuits “sense and kill” rather than inhibit. This mechanism makes them independent of oncogene addiction and less susceptible to resistance than most targeted therapies, potentially enabling a new generation of highly potent and specific cancer medicines.


Why join us now?

Over the past decade, our team has built and de-risked the therapeutic circuit platform. As we move toward a spinout, this is a rare chance to join at the inflection point where cutting-edge research becomes an early commercial program. You’ll be part of a small, fast-moving, startup-minded team, helping build what could become a future cancer therapy.


What you’ll do:

  • Own and independently execute end-to-end in vivo oncology studies from tumor initiation through decision-grade analysis and reporting.
  • Partner with the team to design studies and translate study plans into executable protocols.
  • Execute and continuously refine a portfolio of in vivo models, including subcutaneous xenografts, orthotopic tumor models, and genetically induced models (including HTVi-initiated systems); establish and qualify new models.
  • Perform hands-on mouse work, including tumor engraftment/initiation, dosing (IV, PO, IP, IT), monitoring, tumor measurements, necropsy, and tissue collection with rigorous documentation.
  • Run longitudinal readouts such as IVIS bioluminescence imaging and blood sampling; perform terminal procedures, including terminal blood collection and perfusion.
  • Lead downstream sample analysis workflows: process tissues for flow cytometry, IHC/IF, or spatial readouts (e.g., seqFISH) and coordinate tasks with the team.
  • Conduct basic data and statistical analysis; build clear figures and concise summaries to inform study decisions and next steps.
  • Support IACUC protocols and amendments; uphold high standards for animal welfare and EH&S compliance.
  • Improve how we operate: upgrade our workflows/SOPs and support mentoring/training.


What qualifications are we looking for?

  • Bachelor’s degree in life sciences (or related) with 4-8 years relevant in vivo experience, or Master’s degree with 2-6 years relevant in vivo experience
  • Strong hands-on in vivo experience, including mouse handling, HTVi, common dosing routes (IV, PO, IT), and endpoint procedures (necropsy, tissue collection).
  • Demonstrated ability to build, own, and optimize workflows and SOPs.
  • High rigor, strong documentation habits, and attention to detail.
  • Familiarity with IACUC protocols and EH&S regulations; commitment to humane animal work.
  • Proactive communicator; ownership mindset; collaborative teammate.


Nice to Haves:

  • Experience across multiple tumor models (subcutaneous, orthotopic, genetically induced).
  • Prior experience in an early-stage startup (
Not Specified
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